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Papers authored by Oorschot V

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Efficient IgM assembly and secretion require the plasma cell induced endoplasmic reticulum protein pERp1.

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van Anken E, Pena F, Hafkemeijer N, Christis C, Romijn EP, Grauschopf U, Oorschot VM, Pertel T, Engels S, Ora A, Lástun V, Glockshuber R, Klumperman J, Heck AJ, Luban J, and Braakman I

Proceedings of the National Academy of Sciences of the United States of America 106(40):17019-24, 2009 Oct 6 - Who cited this? | PubMed ID: 19805154 | Fulltext

mTrs130 is a component of a mammalian TRAPPII complex, a Rab1 GEF that binds to COPI-coated vesicles.

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Yamasaki A, Menon S, Yu S, Barrowman J, Meerloo T, Oorschot V, Klumperman J, Satoh A, and Ferro-Novick S

Molecular biology of the cell 20(19):4205-15, 2009 Oct - Who cited this? | PubMed ID: 19656848 | Fulltext

Intracellular activation of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus by nonpeptide agonists.

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Robben JH, Kortenoeven ML, Sze M, Yae C, Milligan G, Oorschot VM, Klumperman J, Knoers NV, and Deen PM

Proceedings of the National Academy of Sciences of the United States of America 106(29):12195-200, 2009 Jul 21 - Who cited this? | PubMed ID: 19587238 | Fulltext

Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex.

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ten Klooster JP, Jansen M, Yuan J, Oorschot V, Begthel H, Di Giacomo V, Colland F, de Koning J, Maurice MM, Hornbeck P, and Clevers H

Developmental cell 16(4):551-62, 2009 Apr - Who cited this? | PubMed ID: 19386264 | Fulltext

Correlative light-electron microscopy (CLEM) combining live-cell imaging and immunolabeling of ultrathin cryosections.

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van Rijnsoever C, Oorschot V, and Klumperman J

Nature methods 5(11):973-80, 2008 Nov - Who cited this? | PubMed ID: 18974735 | Fulltext

Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation.

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Blanchet MH, Le Good JA, Mesnard D, Oorschot V, Baflast S, Minchiotti G, Klumperman J, and Constam DB

The EMBO journal 27(19):2580-91, 2008 Oct 8 - Who cited this? | PubMed ID: 18772886 | Fulltext

The RapGEF PDZ-GEF2 is required for maturation of cell-cell junctions.

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Dubé N, Kooistra MR, Pannekoek WJ, Vliem MJ, Oorschot V, Klumperman J, Rehmann H, and Bos JL

Cellular signalling, 2008 May 23 - Who cited this? | PubMed ID: 18585005 | Fulltext

PTRF-Cavin, a conserved cytoplasmic protein required for caveola formation and function.

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Hill MM, Bastiani M, Luetterforst R, Kirkham M, Kirkham A, Nixon SJ, Walser P, Abankwa D, Oorschot VM, Martin S, Hancock JF, and Parton RG

Cell 132(1):113, 2008 Jan 11 - Who cited this? | PubMed ID: 18191225 | Fulltext

Cripto localizes nodal at the limiting membrane of early endosomes.

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Blanchet MH, Le Good JA, Oorschot V, Baflast S, Minchiotti G, Klumperman J, and Constam DB

Science signaling 1(45):ra13, 2008 - Who cited this? | PubMed ID: 19001664 | Fulltext

Caveolin-1 is transported to multivesicular bodies after albumin-induced endocytosis of caveolae in HepG2 cells.

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Botos E, Klumperman J, Oorschot V, Igyártó B, Magyar A, Oláh M, and Kiss AL

Journal of cellular and molecular medicine, 2007 Dec 5 - Who cited this? | PubMed ID: 18053095 | Fulltext

S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover.

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Mieulet V, Roceri M, Espeillac C, Sotiropoulos A, Ohanna M, Oorschot V, Klumperman J, Sandri M, and Pende M

American journal of physiology. Cell physiology 293(2):C712-22, 2007 Aug - Who cited this? | PubMed ID: 17494629 | Fulltext

Rescue of a nephrogenic diabetes insipidus-causing vasopressin V2 receptor mutant by cell-penetrating peptides.

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Oueslati M, Hermosilla R, Schönenberger E, Oorschot V, Beyermann M, Wiesner B, Schmidt A, Klumperman J, Rosenthal W, and Schülein R

The Journal of biological chemistry 282(28):20676, 2007 Jul 13 - Who cited this? | PubMed ID: 17491025 | Fulltext

Involvement of a Golgi-resident GPI-anchored protein in maintenance of the Golgi structure.

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Li X, Kaloyanova D, van Eijk M, Eerland R, van der Goot G, Oorschot V, Klumperman J, Lottspeich F, Starkuviene V, Wieland FT, and Helms JB

Molecular biology of the cell 18(4):1261, 2007 Apr - Who cited this? | PubMed ID: 17251550 | Fulltext

Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel.

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Kamsteeg EJ, Hendriks G, Boone M, Konings IB, Oorschot V, van der Sluijs P, Klumperman J, and Deen PM

Proceedings of the National Academy of Sciences of the United States of America 103(48):18344-9, 2006 Nov 28 - Who cited this? | PubMed ID: 17101973 | Fulltext

A viral protein that blocks Arf1-mediated COP-I assembly by inhibiting the guanine nucleotide exchange factor GBF1.

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Wessels E, Duijsings D, Niu TK, Neumann S, Oorschot VM, de Lange F, Lanke KH, Klumperman J, Henke A, Jackson CL, Melchers WJ, and van Kuppeveld FJ

Developmental cell 11(2):191-201, 2006 Aug - Who cited this? | PubMed ID: 16890159 | Fulltext

Presenilin-1-mediated retention of APP derivatives in early biosynthetic compartments.

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Réchards M, Xia W, Oorschot V, van Dijk S, Annaert W, Selkoe DJ, and Klumperman J

Traffic (Copenhagen, Denmark) 7(3):354, 2006 Mar - Who cited this? | PubMed ID: 16497228 | Fulltext

Sorting nexin-2 is associated with tubular elements of the early endosome, but is not essential for retromer-mediated endosome-to-TGN transport.

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Carlton JG, Bujny MV, Peter BJ, Oorschot VM, Rutherford A, Arkell RS, Klumperman J, McMahon HT, and Cullen PJ

Journal of cell science 118(Pt 19):4527-39, 2005 Oct 1 - Who cited this? | PubMed ID: 16179610 | Fulltext

Sorting nexin 17 facilitates LRP recycling in the early endosome.

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van Kerkhof P, Lee J, McCormick L, Tetrault E, Lu W, Schoenfish M, Oorschot V, Strous GJ, Klumperman J, and Bu G

The EMBO journal 24(16):2851-61, 2005 Aug 17 - Who cited this? | PubMed ID: 16052210 | Fulltext

Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides.

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Carlton J, Bujny M, Peter BJ, Oorschot VM, Rutherford A, Mellor H, Klumperman J, McMahon HT, and Cullen PJ

Current biology : CB 14(20):1791, 2004 Oct 26 - Who cited this? | PubMed ID: 15498486 | Fulltext

Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway.

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Esselens C, Oorschot V, Baert V, Raemaekers T, Spittaels K, Serneels L, Zheng H, Saftig P, De Strooper B, Klumperman J, and Annaert W

The Journal of cell biology 166(7):1041-54, 2004 Sep 27 - Who cited this? | PubMed ID: 15452145 | Fulltext

Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins.

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Peden AA, Oorschot V, Hesser BA, Austin CD, Scheller RH, and Klumperman J

The Journal of cell biology 164(7):1065-76, 2004 Mar 29 - Who cited this? | PubMed ID: 15051738 | Fulltext

Glycosylation is important for cell surface expression of the water channel aquaporin-2 but is not essential for tetramerization in the endoplasmic reticulum.

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Hendriks G, Koudijs M, van Balkom BW, Oorschot V, Klumperman J, Deen PM, and van der Sluijs P

The Journal of biological chemistry 279(4):2975-83, 2004 Jan 23 - Who cited this? | PubMed ID: 14593099 | Fulltext

Overall major histocompatibility complex class I expression is not downregulated in cervix cancer, as detected by immunoelectron microscopy.

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van Eijkeren MA, Roovers JP, Oorschot V, and Geuze HJ

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 14(2):317-21, 2004 - Who cited this? | PubMed ID: 15086732 | Fulltext

Quantification of synapse formation and maintenance in vivo in the absence of synaptic release.

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Bouwman J, Maia AS, Camoletto PG, Posthuma G, Roubos EW, Oorschot VM, Klumperman J, and Verhage M

Neuroscience 126(1):115-26, 2004 - Who cited this? | PubMed ID: 15145078 | Fulltext

Presenilin-1 exists in both pre- and post-Golgi compartments and recycles via COPI-coated membranes.

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Réchards M, Xia W, Oorschot VM, Selkoe DJ, and Klumperman J

Traffic (Copenhagen, Denmark) 4(8):553-65, 2003 Aug - Who cited this? | PubMed ID: 12839498 | Fulltext

Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes.

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Deneka M, Neeft M, Popa I, van Oort M, Sprong H, Oorschot V, Klumperman J, Schu P, and van der Sluijs P

The EMBO journal 22(11):2645-57, 2003 Jun 2 - Who cited this? | PubMed ID: 12773381 | Fulltext

Rab4 function in membrane recycling from early endosomes depends on a membrane to cytoplasm cycle.

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Mohrmann K, Gerez L, Oorschot V, Klumperman J, and van der Sluijs P

The Journal of biological chemistry 277(35):32029-35, 2002 Aug 30 - Who cited this? | PubMed ID: 12036958 | Fulltext

A novel flat-embedding method to prepare ultrathin cryosections from cultured cells in their in situ orientation.

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Oorschot V, de Wit H, Annaert WG, and Klumperman J

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 50(8):1067-80, 2002 Aug - Who cited this? | PubMed ID: 12133910 | Fulltext

Bilayered clathrin coats on endosomal vacuoles are involved in protein sorting toward lysosomes.

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Sachse M, Urbé S, Oorschot V, Strous GJ, and Klumperman J

Molecular biology of the cell 13(4):1313-28, 2002 Apr - Who cited this? | PubMed ID: 11950941 | Fulltext

Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O.

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Möbius W, Ohno-Iwashita Y, van Donselaar EG, Oorschot VM, Shimada Y, Fujimoto T, Heijnen HF, Geuze HJ, and Slot JW

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 50(1):43-55, 2002 Jan - Who cited this? | PubMed ID: 11748293 | Fulltext

Peri-Golgi vesicles contain retrograde but not anterograde proteins consistent with the cisternal progression model of intra-Golgi transport.

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Martinez-Menárguez JA, Prekeris R, Oorschot VM, Scheller R, Slot JW, Geuze HJ, and Klumperman J

The Journal of cell biology 155(7):1213-24, 2001 Dec 24 - Who cited this? | PubMed ID: 11748250 | Fulltext

Glycosphingolipids are required for sorting melanosomal proteins in the Golgi complex.

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Sprong H, Degroote S, Claessens T, van Drunen J, Oorschot V, Westerink BH, Hirabayashi Y, Klumperman J, van der Sluijs P, and van Meer G

The Journal of cell biology 155(3):369-80, 2001 Oct 29 - Who cited this? | PubMed ID: 11673476 | Fulltext

Subdomain-specific localization of CLIMP-63 (p63) in the endoplasmic reticulum is mediated by its luminal alpha-helical segment.

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Klopfenstein DR, Klumperman J, Lustig A, Kammerer RA, Oorschot V, and Hauri HP

The Journal of cell biology 153(6):1287-300, 2001 Jun 11 - Who cited this? | PubMed ID: 11402071 | Fulltext

Syntaxin 17 is abundant in steroidogenic cells and implicated in smooth endoplasmic reticulum membrane dynamics.

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Steegmaier M, Oorschot V, Klumperman J, and Scheller RH

Molecular biology of the cell 11(8):2719-31, 2000 Aug - Who cited this? | PubMed ID: 10930465 | Fulltext

A phosphorylation site regulates sorting of the vesicular acetylcholine transporter to dense core vesicles.

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Krantz DE, Waites C, Oorschot V, Liu Y, Wilson RI, Tan PK, Klumperman J, and Edwards RH

The Journal of cell biology 149(2):379-96, 2000 Apr 17 - Who cited this? | PubMed ID: 10769030 | Fulltext

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.

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Pende M, Kozma SC, Jaquet M, Oorschot V, Burcelin R, Le Marchand-Brustel Y, Klumperman J, Thorens B, and Thomas G

Nature 408(6815):994-7, 2000 - Who cited this? | PubMed ID: 11140689 | Fulltext

Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking.

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Prekeris R, Yang B, Oorschot V, Klumperman J, and Scheller RH

Molecular biology of the cell 10(11):3891, 1999 Nov - Who cited this? | PubMed ID: 10564279 | Fulltext

The recycling pathway of protein ERGIC-53 and dynamics of the ER-Golgi intermediate compartment.

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Klumperman J, Schweizer A, Clausen H, Tang BL, Hong W, Oorschot V, and Hauri HP

Journal of cell science 111 ( Pt 22):3411-25, 1998 Nov - Who cited this? | PubMed ID: 9788882 | Fulltext

Generation and characterization of monoclonal antibodies to alveolar type II cell lamellar body membrane.

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Zen K, Notarfrancesco K, Oorschot V, Slot JW, Fisher AB, and Shuman H

The American journal of physiology 275(1 Pt 1):L172-83, 1998 Jul - Who cited this? | PubMed ID: 9688949 | Fulltext

Localization, dynamics, and protein interactions reveal distinct roles for ER and Golgi SNAREs.

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Hay JC, Klumperman J, Oorschot V, Steegmaier M, Kuo CS, and Scheller RH

The Journal of cell biology 141(7):1489-502, 1998 Jun 29 - Who cited this? | PubMed ID: 9647643 | Fulltext

Intracellular routes and selective retention of antigens in mildly acidic cathepsin D/lysosome-associated membrane protein-1/MHC class II-positive vesicles in immature dendritic cells.

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Lutz MB, Rovere P, Kleijmeer MJ, Rescigno M, Assmann CU, Oorschot VM, Geuze HJ, Trucy J, Demandolx D, Davoust J, and Ricciardi-Castagnoli P

Journal of immunology (Baltimore, Md. : 1950) 159(8):3707-16, 1997 Oct 15 - Who cited this? | PubMed ID: 9378956 | Fulltext

Thrombin stimulates glucose transport in human platelets via the translocation of the glucose transporter GLUT-3 from alpha-granules to the cell surface.

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Heijnen HF, Oorschot V, Sixma JJ, Slot JW, and James DE

The Journal of cell biology 138(2):323-30, 1997 Jul 28 - Who cited this? | PubMed ID: 9230074 | Fulltext

Glucose transporter (GLUT-4) is targeted to secretory granules in rat atrial cardiomyocytes.

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Slot JW, Garruti G, Martin S, Oorschot V, Posthuma G, Kraegen EW, Laybutt R, Thibault G, and James DE

The Journal of cell biology 137(6):1243-54, 1997 Jun 16 - Who cited this? | PubMed ID: 9182659 | Fulltext

A newly identified antigen retention compartment in the FSDC precursor dendritic cell line.

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Lutz MB, Rovere P, Kleijmeer MJ, Assmann CU, Oorschot VM, Rescigno M, Geuze HJ, Davoust J, and Ricciardi-Castagnoli P

Advances in experimental medicine and biology 417:167-9, 1997 - Who cited this? | PubMed ID: 9286355 | Fulltext

Targeting signal and subcellular compartments involved in the intracellular trafficking of HLA-DMB.

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Copier J, Kleijmeer MJ, Ponnambalam S, Oorschot V, Potter P, Trowsdale J, and Kelly A

Journal of immunology (Baltimore, Md. : 1950) 157(3):1017-27, 1996 Aug 1 - Who cited this? | PubMed ID: 8757605 | Fulltext

A novel class of clathrin-coated vesicles budding from endosomes.

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Stoorvogel W, Oorschot V, and Geuze HJ

The Journal of cell biology 132(1-2):21-33, 1996 Jan - Who cited this? | PubMed ID: 8567724 | Fulltext

Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes.

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Peters PJ, Raposo G, Neefjes JJ, Oorschot V, Leijendekker RL, Geuze HJ, and Ploegh HL

The Journal of experimental medicine 182(2):325-34, 1995 Aug 1 - Who cited this? | PubMed ID: 7629497 | Fulltext

Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells.

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Nijman HW, Kleijmeer MJ, Ossevoort MA, Oorschot VM, Vierboom MP, van de Keur M, Kenemans P, Kast WM, Geuze HJ, and Melief CJ

The Journal of experimental medicine 182(1):163-74, 1995 Jul 1 - Who cited this? | PubMed ID: 7790816 | Fulltext

Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments.

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Peters PJ, Hsu VW, Ooi CE, Finazzi D, Teal SB, Oorschot V, Donaldson JG, and Klausner RD

The Journal of cell biology 128(6):1003-17, 1995 Mar - Who cited this? | PubMed ID: 7896867 | Fulltext

The cytoplasmic tail of mouse hepatitis virus M protein is essential but not sufficient for its retention in the Golgi complex.

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Locker JK, Klumperman J, Oorschot V, Horzinek MC, Geuze HJ, and Rottier PJ

The Journal of biological chemistry 269(45):28263-9, 1994 Nov 11 - Who cited this? | PubMed ID: 7961764 | Fulltext

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