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Papers authored by Omura S

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Hydroruthenation triggered catalytic conversion of dialdehydes and keto aldehydes to lactones.

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Omura S, Fukuyama T, Murakami Y, Okamoto H, and Ryu I

Chemical communications (Cambridge, England)(44):6741-3, 2009 Nov 28 - Who cited this? | PubMed ID: 19885464 | Fulltext

Polymyxin B identified as an inhibitor of alternative NADH dehydrogenase and malate: quinone oxidoreductase from the Gram-positive bacterium Mycobacterium smegmatis.

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Mogi T, Murase Y, Mori M, Shiomi K, Omura S, Paranagama MP, and Kita K

Journal of biochemistry 146(4):491-9, 2009 Oct - Who cited this? | PubMed ID: 19564154 | Fulltext

Mechanism by which the lectin actinohivin blocks HIV infection of target cells.

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Tanaka H, Chiba H, Inokoshi J, Kuno A, Sugai T, Takahashi A, Ito Y, Tsunoda M, Suzuki K, Takénaka A, Sekiguchi T, Umeyama H, Hirabayashi J, and Omura S

Proceedings of the National Academy of Sciences of the United States of America 106(37):15633-8, 2009 Sep 15 - Who cited this? | PubMed ID: 19717426 | Fulltext

Human salivary gland stem/progenitor cells remain dormant even after irradiation.

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Tatsuishi Y, Hirota M, Kishi T, Adachi M, Fukui T, Mitsudo K, Aoki S, Matsui Y, Omura S, Taniguchi H, and Tohnai I

International journal of molecular medicine 24(3):361-6, 2009 Sep - Who cited this? | PubMed ID: 19639228 | Fulltext

Molecular modeling of human acidic mammalian chitinase in complex with the natural-product cyclopentapeptide chitinase inhibitor argifin.

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Gouda H, Terashima S, Iguchi K, Sugawara A, Saito Y, Yamamoto T, Hirose T, Shiomi K, Sunazuka T, Omura S, and Hirono S

Bioorganic & medicinal chemistry 17(17):6270-8, 2009 Sep 1 - Who cited this? | PubMed ID: 19666229 | Fulltext

Siccanin rediscovered as a species-selective succinate dehydrogenase inhibitor.

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Mogi T, Kawakami T, Arai H, Igarashi Y, Matsushita K, Mori M, Shiomi K, Omura S, Harada S, and Kita K

Journal of biochemistry 146(3):383-7, 2009 Sep - Who cited this? | PubMed ID: 19505951 | Fulltext

Rapid detection of vaginal Candida species by newly developed immunochromatography.

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Matsui H, Hanaki H, Takahashi K, Yokoyama A, Nakae T, Sunakawa K, and Omura S

Clinical and vaccine immunology : CVI 16(9):1366-8, 2009 Sep - Who cited this? | PubMed ID: 19656990 | Fulltext

Solid-phase total synthesis of the chitinase inhibitor Argadin using a supported acetal resin.

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Hirose T, Sunazuka T, Sugawara A, Noguchi Y, Tanaka T, Iguchi K, Yamamoto T, Gouda H, Shiomi K, and Omura S

The Journal of antibiotics 62(9):495-500, 2009 Sep - Who cited this? | PubMed ID: 19575041 | Fulltext

Biochemical and spectroscopic properties of cyanide-insensitive quinol oxidase from Gluconobacter oxydans.

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Mogi T, Ano Y, Nakatsuka T, Toyama H, Muroi A, Miyoshi H, Migita CT, Ui H, Shiomi K, Omura S, Kita K, and Matsushita K

Journal of biochemistry 146(2):263-71, 2009 Aug - Who cited this? | PubMed ID: 19416958 | Fulltext

Xanthoradones, new potentiators of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2 II. Structure elucidation.

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Yamazaki H, Omura S, and Tomoda H

The Journal of antibiotics 62(8):435-7, 2009 Aug - Who cited this? | PubMed ID: 19609292 | Fulltext

Xanthoradones, new potentiators of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2: I. Taxonomy, fermentation, isolation and biological properties.

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Yamazaki H, Nonaka K, Masuma R, Omura S, and Tomoda H

The Journal of antibiotics 62(8):431-4, 2009 Aug - Who cited this? | PubMed ID: 19629141 | Fulltext

Microarray analysis of gene expression in rat alveolar epithelial cells exposed to fractionated organic extracts of diesel exhaust particles.

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Omura S, Koike E, and Kobayashi T

Toxicology 262(1):65-72, 2009 Jul 28 - Who cited this? | PubMed ID: 19465080 | Fulltext

Merobatzelladines A and B, anti-infective tricyclic guanidines from a marine sponge Monanchora sp.

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Takishima S, Ishiyama A, Iwatsuki M, Otoguro K, Yamada H, Omura S, Kobayashi H, van Soest RW, and Matsunaga S

Organic letters 11(12):2655-8, 2009 Jun 18 - Who cited this? | PubMed ID: 19469518 | Fulltext

Antitrypanosomal activity of some pregnane glycosides isolated from Caralluma species.

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Abdel-Sattar E, Shehab NG, Ichino C, Kiyohara H, Ishiyama A, Otoguro K, Omura S, and Yamada H

Phytomedicine : international journal of phytotherapy and phytopharmacology 16(6-7):659-64, 2009 Jun - Who cited this? | PubMed ID: 19345077 | Fulltext

Enantioselective total synthesis of atpenin A5.

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Ohtawa M, Ogihara S, Sugiyama K, Shiomi K, Harigaya Y, Nagamitsu T, and Omura S

The Journal of antibiotics 62(6):289-94, 2009 Jun - Who cited this? | PubMed ID: 19373276 | Fulltext

In vitro and in vivo antitrypanosomal activities of three peptide antibiotics: leucinostatin A and B, alamethicin I and tsushimycin.

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Ishiyama A, Otoguro K, Iwatsuki M, Namatame M, Nishihara A, Nonaka K, Kinoshita Y, Takahashi Y, Masuma R, Shiomi K, Yamada H, and Omura S

The Journal of antibiotics 62(6):303-8, 2009 Jun - Who cited this? | PubMed ID: 19407848 | Fulltext

In vitro and in vivo antitrypanosomal activities of three peptide antibiotics: leucinostatin A and B, alamethicin I and tsushimycin.

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Ishiyama A, Otoguro K, Iwatsuki M, Namatame M, Nishihara A, Nonaka K, Kinoshita Y, Takahashi Y, Masuma R, Shiomi K, Yamada H, and Omura S

The Journal of antibiotics 62(6):343, 2009 Jun - Who cited this? | PubMed ID: 19557035 | Fulltext

Ilumatobacter fluminis gen. nov., sp. nov., a novel actinobacterium isolated from the sediment of an estuary.

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Matsumoto A, Kasai H, Matsuo Y, Omura S, Shizuri Y, and Takahashi Y

The Journal of general and applied microbiology 55(3):201-5, 2009 Jun - Who cited this? | PubMed ID: 19590147 | Fulltext

Lys17 in the 'lasso' peptide lariatin A is responsible for anti-mycobacterial activity.

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Iwatsuki M, Koizumi Y, Gouda H, Hirono S, Tomoda H, and Omura S

Bioorganic & medicinal chemistry letters 19(10):2888-90, 2009 May 15 - Who cited this? | PubMed ID: 19362475 | Fulltext

Computer-aided rational molecular design of argifin-derivatives with increased inhibitory activity against chitinase B from Serratia marcescens.

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Gouda H, Sunazuka T, Iguchi K, Sugawara A, Hirose T, Noguchi Y, Saito Y, Yanai Y, Yamamoto T, Watanabe T, Shiomi K, Omura S, and Hirono S

Bioorganic & medicinal chemistry letters 19(10):2630-3, 2009 May 15 - Who cited this? | PubMed ID: 19395258 | Fulltext

Chitinase inhibitors: extraction of the active framework from natural argifin and use of in situ click chemistry.

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Hirose T, Sunazuka T, Sugawara A, Endo A, Iguchi K, Yamamoto T, Ui H, Shiomi K, Watanabe T, Sharpless KB, and Omura S

The Journal of antibiotics 62(5):277-82, 2009 May - Who cited this? | PubMed ID: 19329983 | Fulltext

Antiplasmodial and antitrypanosomal activity of plants from the Kingdom of Saudi Arabia.

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Abdel-Sattar E, Harraz FM, Al-Ansari SM, El-Mekkawy S, Ichino C, Kiyohara H, Otoguro K, Omura S, and Yamada H

Natural medicines = Shoyakugaku zasshi / The Japanese Society of Pharmacognosy 63(2):232-9, 2009 Apr - Who cited this? | PubMed ID: 19067114 | Fulltext

Argifin; efficient solid phase total synthesis and evalution of analogues of acyclic peptide.

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Sunazuka T, Sugawara A, Iguchi K, Hirose T, Nagai K, Noguchi Y, Saito Y, Yamamoto T, Ui H, Gouda H, Shiomi K, Watanabe T, and Omura S

Bioorganic & medicinal chemistry 17(7):2751-8, 2009 Apr 1 - Who cited this? | PubMed ID: 19297173 | Fulltext

The Selectivity of Beauveriolide Derivatives in Inhibition toward the Two Isozymes of Acyl-CoA : cholesterol Acyltransferase.

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Ohshiro T, Matsuda D, Nagai K, Doi T, Sunazuka T, Takahashi T, Rudel LL, Omura S, and Tomoda H

Chemical & pharmaceutical bulletin 57(4):377-81, 2009 Apr - Who cited this? | PubMed ID: 19336931 | Fulltext

Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages, produced by Penicillium cecidicola FKI-3765-1: I. Taxonomy, fermentation, isolation and biological properties.

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Yamazaki H, Kobayashi K, Matsuda D, Nonaka K, Masuma R, Omura S, and Tomoda H

The Journal of antibiotics 62(4):195-200, 2009 Apr - Who cited this? | PubMed ID: 19300470 | Fulltext

Pentacecilides, new inhibitors of lipid droplet formation in mouse macrophages produced by Penicillium cecidicola FKI-3765-1: II. Structure elucidation.

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Yamazaki H, Omura S, and Tomoda H

The Journal of antibiotics 62(4):207-11, 2009 Apr - Who cited this? | PubMed ID: 19300471 | Fulltext

Novel Mitochondrial Complex II Isolated from Trypanosoma cruzi Is Composed of 12 Peptides Including a Heterodimeric Ip Subunit.

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Morales J, Mogi T, Mineki S, Takashima E, Mineki R, Hirawake H, Sakamoto K, Omura S, and Kita K

The Journal of biological chemistry 284(11):7255-63, 2009 Mar 13 - Who cited this? | PubMed ID: 19122194 | Fulltext

Identification of new inhibitors for alternative NADH dehydrogenase (NDH-II).

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Mogi T, Matsushita K, Murase Y, Kawahara K, Miyoshi H, Ui H, Shiomi K, Omura S, and Kita K

FEMS microbiology letters 291(2):157-61, 2009 Feb - Who cited this? | PubMed ID: 19076229 | Fulltext

Antibiotics LL-Z1272 identified as novel inhibitors discriminating bacterial and mitochondrial quinol oxidases.

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Mogi T, Ui H, Shiomi K, Omura S, Miyoshi H, and Kita K

Biochimica et biophysica acta 1787(2):129-33, 2009 Feb - Who cited this? | PubMed ID: 19111521 | Fulltext

Role of dexamethasone and oncostatin m on the formation of vacuoles in human fetal liver cells.

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Teramoto T, Matsunaga T, Toba M, Sunazuka T, Omura S, and Ohmori S

Biological & pharmaceutical bulletin 32(2):209-12, 2009 Feb - Who cited this? | PubMed ID: 19182377 | Fulltext

Total synthesis of amidepsine B and revision of its absolute configuration.

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Nagamitsu T, Marumoto K, Nagayasu A, Fukuda T, Arima S, Uchida R, Ohshiro T, Harigaya Y, Tomoda H, and Omura S

The Journal of antibiotics 62(2):69-74, 2009 Feb - Who cited this? | PubMed ID: 19198634 | Fulltext

Structure Determination and Total Synthesis of Bottromycin A(2): A Potent Antibiotic against MRSA and VRE.

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Shimamura H, Gouda H, Nagai K, Hirose T, Ichioka M, Furuya Y, Kobayashi Y, Hirono S, Sunazuka T, and Omura S

Angewandte Chemie (International ed. in English) 48(5):914-7, 2009 - Who cited this? | PubMed ID: 19115340 | Fulltext

Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine.

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Nakano H and Omura S

The Journal of antibiotics 62(1):17-26, 2009 Jan - Who cited this? | PubMed ID: 19132059 | Fulltext

Expression of two human acyl-CoA:diacylglycerol acyltransferase isozymes in yeast and selectivity of microbial inhibitors toward the isozymes.

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Inokoshi J, Kawamoto K, Takagi Y, Matsuhama M, Omura S, and Tomoda H

The Journal of antibiotics 62(1):51-4, 2009 Jan - Who cited this? | PubMed ID: 19132064 | Fulltext

Reaching for new heights: the Journal of Antibiotics and NPG.

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Omura S

The Journal of antibiotics 62(1):1, 2009 Jan - Who cited this? | PubMed ID: 19198640 | Fulltext

New lycorine-type alkaloid from Lycoris traubii and evaluation of antitrypanosomal and antimalarial activities of lycorine derivatives.

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Toriizuka Y, Kinoshita E, Kogure N, Kitajima M, Ishiyama A, Otoguro K, Yamada H, Omura S, and Takayama H

Bioorganic & medicinal chemistry 16(24):10182-9, 2008 Dec 15 - Who cited this? | PubMed ID: 19013823 | Fulltext

Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin.

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Dohi Y, Ikura T, Hoshikawa Y, Katoh Y, Ota K, Nakanome A, Muto A, Omura S, Ohta T, Ito A, Yoshida M, Noda T, and Igarashi K

Nature structural & molecular biology 15(12):1246-54, 2008 Dec - Who cited this? | PubMed ID: 19011633 | Fulltext

Actinomadura maheshkhaliensis sp. nov., a novel actinomycete isolated from mangrove rhizosphere soil of Maheshkhali, Bangladesh.

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Ara I, Matsumoto A, Abdul Bakir M, Kudo T, Omura S, and Takahashi Y

The Journal of general and applied microbiology 54(6):335-42, 2008 Dec - Who cited this? | PubMed ID: 19164876 | Fulltext

Upregulation of Heme Oxygenase-1 Combined with Increased Adiponectin Lowers Blood Pressure in Diabetic Spontaneously Hypertensive Rats through a Reduction in Endothelial Cell Dysfunction, Apoptosis and Oxidative Stress.

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Cao J, Drummond G, Inoue K, Sodhi K, Li XY, and Omura S

International journal of molecular sciences 9(12):2388-406, 2008 Dec - Who cited this? | PubMed ID: 19330083 | Fulltext

Relative and absolute stereochemistry of quinadoline B, an inhibitor of lipid droplet synthesis in macrophages.

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Koyama N, Inoue Y, Sekine M, Hayakawa Y, Homma H, Omura S, and Tomoda H

Organic letters 10(22):5273-6, 2008 Nov 20 - Who cited this? | PubMed ID: 18922003 | Fulltext

Ruthenium Hydride-Catalyzed Addition of Aldehydes to Dienes Leading to beta,gamma-Unsaturated Ketones.

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Omura S, Fukuyama T, Horiguchi J, Murakami Y, and Ryu I

Journal of the American Chemical Society 130(43):14094-5, 2008 Oct 29 - Who cited this? | PubMed ID: 18841894 | Fulltext

Total synthesis of salinosporamide A.

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Fukuda T, Sugiyama K, Arima S, Harigaya Y, Nagamitsu T, and Omura S

Organic letters 10(19):4239-42, 2008 Oct 2 - Who cited this? | PubMed ID: 18763797 | Fulltext

Marihabitans asiaticum gen. nov., sp. nov., a meso-diaminopimelic acid-containing member of the family Intrasporangiaceae.

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Kageyama A, Haga T, Kasai H, Shizuri Y, Omura S, and Takahashi Y

International journal of systematic and evolutionary microbiology 58(Pt 10):2429-32, 2008 Oct - Who cited this? | PubMed ID: 18842869 | Fulltext

In Vitro and in Vivo Antitrypanosomal Activitiy of Two Microbial Metabolites, KS-505a and Alazopeptin.

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Ishiyama A, Otoguro K, Namatame M, Nishihara A, Furusawa T, Masuma R, Shiomi K, Takahashi Y, Ichimura M, Yamada H, and Omura S

The Journal of antibiotics 61(10):627-32, 2008 Oct - Who cited this? | PubMed ID: 19168977 | Fulltext

Citrinamides, new potentiators of antifungal miconazole activity, produced by Penicillium sp. FKI-1938.

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Fukuda T, Hasegawa Y, Sakabe Y, Tomoda H, and Omura S

The Journal of antibiotics 61(9):550-5, 2008 Sep - Who cited this? | PubMed ID: 19160522 | Fulltext

Erythromycin derivatives inhibit HIV-1 replication in macrophages through modulation of MAPK activity to induce small isoforms of C/EBPbeta.

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Komuro I, Sunazuka T, Akagawa KS, Yokota Y, Iwamoto A, and Omura S

Proceedings of the National Academy of Sciences of the United States of America 105(34):12509, 2008 Aug 26 - Who cited this? | PubMed ID: 18719105 | Fulltext

EM703, A NEW DERIVATIVE OF ERYTHROMYCIN, INHIBITS TRANSFORMING GRWTH FACTOR-beta SIGNALING IN HUMAN LUNG FIBROBLASTS.

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Yu C, Azuma A, Li Y, Wang C, Abe S, Usuki J, Matsuda K, Kudoh S, Sunazuka T, and Omura S

Experimental lung research 34(6):343, 2008 Aug - Who cited this? | PubMed ID: 18600500 | Fulltext

Acylated pregnane glycosides from Caralluma tuberculata and their antiparasitic activity.

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Abdel-Sattar E, Harraz FM, Al-Ansari SM, El-Mekkawy S, Ichino C, Kiyohara H, Ishiyama A, Otoguro K, Omura S, and Yamada H

Phytochemistry 69(11):2180, 2008 Aug - Who cited this? | PubMed ID: 18614190 | Fulltext

Synthesis and biological evaluation of a focused library of beauveriolides.

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Nagai K, Doi T, Ohshiro T, Sunazuka T, Tomoda H, Takahashi T, and Omura S

Bioorganic & medicinal chemistry letters 18(15):4397-400, 2008 Aug 1 - Who cited this? | PubMed ID: 18620856 | Fulltext

Selectivity of Pyripyropene Derivatives in Inhibition toward Acyl-CoA:cholesterol Acyltransferase 2 Isozyme.

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Ohshiro T, Ohte S, Matsuda D, Ohtawa M, Nagamitsu T, Sunazuka T, Harigaya Y, Rudel LL, Omura S, and Tomoda H

The Journal of antibiotics 61(8):503-8, 2008 Aug - Who cited this? | PubMed ID: 18997389 | Fulltext

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