Papers authored by Nonoshita K

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Discovery of trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H),1'-cyclohexane]-4'-carboxamide, a potent and orally active neuropeptide Y Y5 receptor antagonist.
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Haga Y, Sakamoto T, Shibata T, Nonoshita K, Ishikawa M, Suga T, Takahashi H, Takahashi T, Takahashi H, Ando M, Murai T, Gomori A, Oda Z, Kitazawa H, Mitobe Y, Kanesaka M, 
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Bioorganic & medicinal chemistry 17(19):6971-82, 2009 Oct 1 - Who cited this? | PubMed ID: 19720539 | Fulltext
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Identification of positron emission tomography ligands for NPY Y5 receptors in the brain.
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Takahashi H, Haga Y, Shibata T, Nonoshita K, Sakamoto T, Moriya M, Ohe T, Chiba M, Mitobe Y, Kitazawa H, Iwaasa H, Ishihara A, Ishii Y, Kanatani A, and Fukami T
Bioorganic & medicinal chemistry letters 19(18):5436-9, 2009 Sep 15 - Who cited this? | PubMed ID: 19679469 | Fulltext
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Discovery of novel 2-(pyridine-2-yl)-1H-benzimidazole derivatives as potent glucokinase activators.
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Ishikawa M, Nonoshita K, Ogino Y, Nagae Y, Tsukahara D, Hosaka H, Maruki H, Ohyama S, Yoshimoto R, Sasaki K, Nagata Y, Eiki J, and Nishimura T
Bioorganic & medicinal chemistry letters 19(15):4450-4, 2009 Aug 1 - Who cited this? | PubMed ID: 19540111 | Fulltext
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Novel orally active NPY Y5 receptor antagonists: Synthesis and structure-activity relationship of spiroindoline class compounds.
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Sakamoto T, Moriya M, Tsuge H, Takahashi T, Haga Y, Nonoshita K, Okamoto O, Takahashi H, Sakuraba A, Hirohashi T, Shibata T, Kanno T, Ito J, Iwaasa H, Gomori A, Ishihara A, 
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Bioorganic & medicinal chemistry 17(14):5015-26, 2009 Jul 15 - Who cited this? | PubMed ID: 19525116 | Fulltext
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Aryl urea derivatives of spiropiperidines as NPY Y5 receptor antagonists.
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Takahashi T, Haga Y, Sakamoto T, Moriya M, Okamoto O, Nonoshita K, Shibata T, Suga T, Takahashi H, Hirohashi T, Sakuraba A, Gomori A, Iwaasa H, Ohe T, Ishihara A, Ishii Y, 
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Bioorganic & medicinal chemistry letters 19(13):3511-6, 2009 Jul 1 - Who cited this? | PubMed ID: 19464889 | Fulltext
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Identification of novel and orally active spiroindoline NPY Y5 receptor antagonists.
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Sakamoto T, Moriya M, Haga Y, Takahashi T, Shibata T, Okamoto O, Nonoshita K, Kitazawa H, Hidaka M, Gomori A, Iwaasa H, Ishihara A, Kanatani A, Fukami T, Gao YD, Macneil DJ, 
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Bioorganic & medicinal chemistry letters 19(6):1564-8, 2009 Mar 15 - Who cited this? | PubMed ID: 19243937 | Fulltext
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(9S)-9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one, a Selective and Orally Active Neuropeptide Y Y5 Receptor Antagonist.
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Sato N, Jitsuoka M, Shibata T, Hirohashi T, Nonoshita K, Moriya M, Haga Y, Sakuraba A, Ando M, Ohe T, Iwaasa H, Gomori A, Ishihara A, Kanatani A, and Fukami T
Journal of medicinal chemistry, 2008 Jul 19 - Who cited this? | PubMed ID: 18637668 | Fulltext
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Novel potent neuropeptide Y Y5 receptor antagonists: synthesis and structure-activity relationships of phenylpiperazine derivatives.
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Takahashi T, Sakuraba A, Hirohashi T, Shibata T, Hirose M, Haga Y, Nonoshita K, Kanno T, Ito J, Iwaasa H, Kanatani A, Fukami T, and Sato N
Bioorganic & medicinal chemistry 14(22):7501-11, 2006 Nov 15 - Who cited this? | PubMed ID: 16919461 | Fulltext
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Design and synthesis of the potent, orally available, brain-penetrable arylpyrazole class of neuropeptide Y5 receptor antagonists.
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Sato N, Takahashi T, Shibata T, Haga Y, Sakuraba A, Hirose M, Sato M, Nonoshita K, Koike Y, Kitazawa H, Fujino N, Ishii Y, Ishihara A, Kanatani A, and Fukami T
Journal of medicinal chemistry 46(5):666-9, 2003 Feb 27 - Who cited this? | PubMed ID: 12593644 | Fulltext
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A new class of highly potent farnesyl diphosphate-competitive inhibitors of farnesyltransferase.
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Aoyama T, Satoh T, Yonemoto M, Shibata J, Nonoshita K, Arai S, Kawakami K, Iwasawa Y, Sano H, Tanaka K, Monden Y, Kodera T, Arakawa H, Suzuki-Takahashi I, Kamei T, and Tomimoto K
Journal of medicinal chemistry 41(2):143-7, 1998 Jan 15 - Who cited this? | PubMed ID: 9457237 | Fulltext
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