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Papers authored by Nizet V

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Genetic and biochemical modulation of sialic acid O-acetylation on group B Streptococcus: phenotypic and functional impact.

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Weiman S, Dahesh S, Carlin AF, Varki A, Nizet V, and Lewis AL

Glycobiology 19(11):1204-13, 2009 Nov - Who cited this? | PubMed ID: 19643844 | Fulltext

Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin.

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Jann NJ, Schmaler M, Kristian SA, Radek KA, Gallo RL, Nizet V, Peschel A, and Landmann R

Journal of leukocyte biology 86(5):1159-69, 2009 Nov - Who cited this? | PubMed ID: 19638500 | Fulltext

Interdependence of hypoxic and innate immune responses.

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Nizet V and Johnson RS

Nature reviews. Immunology 9(9):609-17, 2009 Sep - Who cited this? | PubMed ID: 19704417 | Fulltext

Color me bad: microbial pigments as virulence factors.

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Liu GY and Nizet V

Trends in microbiology 17(9):406-13, 2009 Sep - Who cited this? | PubMed ID: 19726196 | Fulltext

The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion.

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Uchiyama S, Carlin AF, Khosravi A, Weiman S, Banerjee A, Quach D, Hightower G, Mitchell TJ, Doran KS, and Nizet V

The Journal of experimental medicine 206(9):1845-52, 2009 Aug 31 - Who cited this? | PubMed ID: 19687228 | Fulltext

Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure.

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Lewis AL, Desa N, Hansen EE, Knirel YA, Gordon JI, Gagneux P, Nizet V, and Varki A

Proceedings of the National Academy of Sciences of the United States of America 106(32):13552-7, 2009 Aug 11 - Who cited this? | PubMed ID: 19666579 | Fulltext

NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation.

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Hruz P, Zinkernagel AS, Jenikova G, Botwin GJ, Hugot JP, Karin M, Nizet V, and Eckmann L

Proceedings of the National Academy of Sciences of the United States of America 106(31):12873-8, 2009 Aug 4 - Who cited this? | PubMed ID: 19541630 | Fulltext

Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5.

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Carlin AF, Chang YC, Areschoug T, Lindahl G, Hurtado-Ziola N, King CC, Varki A, and Nizet V

The Journal of experimental medicine 206(8):1691-9, 2009 Aug 3 - Who cited this? | PubMed ID: 19596804 | Fulltext

Innate immunity turned inside-out: antimicrobial defense by phagocyte extracellular traps.

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von Köckritz-Blickwede M and Nizet V

Journal of molecular medicine (Berlin, Germany) 87(8):775-83, 2009 Aug - Who cited this? | PubMed ID: 19444424 | Fulltext

Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results.

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Song Y, Liu CI, Lin FY, No JH, Hensler M, Liu YL, Jeng WY, Low J, Liu GY, Nizet V, Wang AH, and Oldfield E

Journal of medicinal chemistry 52(13):3869-80, 2009 Jul 9 - Who cited this? | PubMed ID: 19456099 | Fulltext

The group B streptococcal serine-rich repeat 1 glycoprotein mediates penetration of the blood-brain barrier.

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van Sorge NM, Quach D, Gurney MA, Sullam PM, Nizet V, and Doran KS

The Journal of infectious diseases 199(10):1479-87, 2009 May 15 - Who cited this? | PubMed ID: 19392623 | Fulltext

Structural and functional dissection of the heterocyclic Peptide cytotoxin streptolysin s.

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Mitchell DA, Lee SW, Pence MA, Markley AL, Limm JD, Nizet V, and Dixon JE

The Journal of biological chemistry 284(19):13004-12, 2009 May 8 - Who cited this? | PubMed ID: 19286651 | Fulltext

From the Cover: Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections.

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Navarini AA, Lang KS, Verschoor A, Recher M, Zinkernagel AS, Nizet V, Odermatt B, Hengartner H, and Zinkernagel RM

Proceedings of the National Academy of Sciences of the United States of America 106(17):7107-12, 2009 Apr 28 - Who cited this? | PubMed ID: 19351895 | Fulltext

Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response.

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Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, and Varki A

Blood 113(14):3333-6, 2009 Apr 2 - Who cited this? | PubMed ID: 19196661 | Fulltext

Cell death during sepsis: integration of disintegration in the inflammatory response to overwhelming infection.

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Pinheiro da Silva F and Nizet V

Apoptosis : an international journal on programmed cell death 14(4):509-21, 2009 Apr - Who cited this? | PubMed ID: 19199035 | Fulltext

Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus.

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Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D, Nizet V, and Oldfield E

Journal of medicinal chemistry 52(4):976-88, 2009 Feb 26 - Who cited this? | PubMed ID: 19191557 | Fulltext

Bacterial phenotype variants in group B streptococcal toxic shock syndrome.

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Sendi P, Johansson L, Dahesh S, Van-Sorge NM, Darenberg J, Norgren M, Sjölin J, Nizet V, and Norrby-Teglund A

Emerging infectious diseases 15(2):223-32, 2009 Feb - Who cited this? | PubMed ID: 19193266 | Fulltext

Streptolysin o promotes group a streptococcus immune evasion by accelerated macrophage apoptosis.

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Timmer AM, Timmer JC, Pence MA, Hsu LC, Ghochani M, Frey TG, Karin M, Salvesen GS, and Nizet V

The Journal of biological chemistry 284(2):862-71, 2009 Jan 9 - Who cited this? | PubMed ID: 19001420 | Fulltext

Relationship between expression of the family of M proteins and lipoteichoic acid to hydrophobicity and biofilm formation in Streptococcus pyogenes.

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Courtney HS, Ofek I, Penfound T, Nizet V, Pence MA, Kreikemeyer B, Podbielbski A, Hasty DL, and Dale JB

PLoS ONE 4(1):e4166, 2009 - Who cited this? | PubMed ID: 19132104 | Fulltext

Erratum.

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Courtney HS, Ofek I, Penfound T, Nizet V, Pence MA, Kreikemeyer B, Podbielski A, Hasty DL, and Dale JB

PLoS ONE 4(1), 2009 - Who cited this? | PubMed ID: 19234625 | Fulltext

Erratum.

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Courtney HS, Ofek I, Penfound T, Nizet V, Pence MA, Kreikemeyer B, Podbielski A, Hasty DL, and Dale JB

PLoS ONE 4(1), 2009 - Who cited this? | PubMed ID: 19238229 | Fulltext

Inactivation of DltA modulates virulence factor expression in Streptococcus pyogenes.

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Cox KH, Ruiz-Bustos E, Courtney HS, Dale JB, Pence MA, Nizet V, Aziz RK, Gerling I, Price SM, and Hasty DL

PLoS ONE 4(4):e5366, 2009 - Who cited this? | PubMed ID: 19401780 | Fulltext

Staphylococcus aureus Panton-Valentine Leukocidin Contributes to Inflammation and Muscle Tissue Injury.

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Tseng CW, Kyme P, Low J, Rocha MA, Alsabeh R, Miller LG, Otto M, Arditi M, Diep BA, Nizet V, Doherty TM, Beenhouwer DO, and Liu GY

PLoS ONE 4(7):e6387, 2009 - Who cited this? | PubMed ID: 19633710 | Fulltext

Differing effects of exogenous or endogenous cathelicidin on macrophage toll-like receptor signaling.

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Pinheiro da Silva F, Gallo RL, and Nizet V

Immunology and cell biology 87(6):496-500, 2009 - Who cited this? | PubMed ID: 19350049 | Fulltext

Strain-associated virulence factors of Streptococcus iniae in hybrid-striped bass.

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Buchanan JT, Colvin KM, Vicknair MR, Patel SK, Timmer AM, and Nizet V

Veterinary microbiology 131(1-2):145, 2008 Sep 18 - Who cited this? | PubMed ID: 18406547 | Fulltext

Mitochondrial missile defense.

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Nizet V and Rothenberg ME

Nature medicine 14(9):910-2, 2008 Sep - Who cited this? | PubMed ID: 18776879 | Fulltext

The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing.

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Zinkernagel AS, Timmer AM, Pence MA, Locke JB, Buchanan JT, Turner CE, Mishalian I, Sriskandan S, Hanski E, and Nizet V

Cell host & microbe 4(2):170, 2008 Aug 14 - Who cited this? | PubMed ID: 18692776 | Fulltext

Point Mutation in the Group B Streptococcal pbp2x Gene Conferring Decreased Susceptibility to {beta}-Lactam Antibiotics.

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Dahesh S, Hensler ME, Van Sorge NM, Gertz RE, Schrag S, Nizet V, and Beall BW

Antimicrobial agents and chemotherapy 52(8):2915-8, 2008 Aug - Who cited this? | PubMed ID: 18541727 | Fulltext

IKKbeta/NF-kappaB and the miscreant macrophage.

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Timmer AM and Nizet V

The Journal of experimental medicine 205(6):1255, 2008 Jun 9 - Who cited this? | PubMed ID: 18519650 | Fulltext

A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide.

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Hsu LC, Ali SR, McGillivray S, Tseng PH, Mariathasan S, Humke EW, Eckmann L, Powell JJ, Nizet V, Dixit VM, and Karin M

Proceedings of the National Academy of Sciences of the United States of America 105(22):7803, 2008 Jun 3 - Who cited this? | PubMed ID: 18511561 | Fulltext

The Ashwell receptor mitigates the lethal coagulopathy of sepsis.

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Grewal PK, Uchiyama S, Ditto D, Varki N, Le DT, Nizet V, and Marth JD

Nature medicine 14(6):648, 2008 Jun - Who cited this? | PubMed ID: 18488037 | Fulltext

A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence.

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Maisey HC, Quach D, Hensler ME, Liu GY, Gallo RL, Nizet V, and Doran KS

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22(6):1715, 2008 Jun - Who cited this? | PubMed ID: 18198218 | Fulltext

Top-down mass spectrometry on low-resolution instruments: characterization of phosphopantetheinylated carrier domains in polyketide and non-ribosomal biosynthetic pathways.

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Meluzzi D, Zheng WH, Hensler M, Nizet V, and Dorrestein PC

Bioorganic & medicinal chemistry letters 18(10):3107-11, 2008 May 15 - Who cited this? | PubMed ID: 18006314 | Fulltext

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha.

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Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, and Karin M

Nature, 2008 Apr 23 - Who cited this? | PubMed ID: 18432192 | Fulltext

Discovery of a widely distributed toxin biosynthetic gene cluster.

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Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, and Dixon JE

Proceedings of the National Academy of Sciences of the United States of America 105(15):5879-84, 2008 Apr 15 - Who cited this? | PubMed ID: 18375757 | Fulltext

Role of Staphylococcus aureus catalase in niche competition against Streptococcus pneumoniae.

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Park B, Nizet V, and Liu GY

Journal of bacteriology 190(7):2275, 2008 Apr - Who cited this? | PubMed ID: 18223076 | Fulltext

A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence.

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Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, and Oldfield E

Science (New York, N.Y.) 319(5868):1391, 2008 Mar 7 - Who cited this? | PubMed ID: 18276850 | Fulltext

Opacity Factor Activity and Epithelial Cell Binding by the Serum Opacity Factor Protein of Streptococcus pyogenes Are Functionally Discrete.

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Gillen CM, Courtney HS, Schulze K, Rohde M, Wilson MR, Timmer AM, Guzman CA, Nizet V, Chhatwal GS, and Walker MJ

The Journal of biological chemistry 283(10):6359-66, 2008 Mar 7 - Who cited this? | PubMed ID: 18180300 | Fulltext

Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence.

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McNamara C, Zinkernagel AS, Macheboeuf P, Cunningham MW, Nizet V, and Ghosh P

Science (New York, N.Y.) 319(5868):1405-8, 2008 Mar 7 - Who cited this? | PubMed ID: 18323455 | Fulltext

Critical Role of HIF-1alpha in Keratinocyte Defense against Bacterial Infection.

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Peyssonnaux C, Boutin AT, Zinkernagel AS, Datta V, Nizet V, and Johnson RS

The Journal of investigative dermatology, 2008 Mar 6 - Who cited this? | PubMed ID: 18323789 | Fulltext

Skin microbiota: a source of disease or defence?.

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Cogen AL, Nizet V, and Gallo RL

The British journal of dermatology 158(3):442-55, 2008 Mar - Who cited this? | PubMed ID: 18275522 | Fulltext

Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes.

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Zinkernagel AS, Peyssonnaux C, Johnson RS, and Nizet V

The Journal of infectious diseases 197(2):214-7, 2008 Jan 15 - Who cited this? | PubMed ID: 18173364 | Fulltext

The GraRS regulatory system controls Staphylococcus aureus susceptibility to antimicrobial host defenses.

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Kraus D, Herbert S, Kristian SA, Khosravi A, Nizet V, Götz F, and Peschel A

BMC microbiology 8:85, 2008 - Who cited this? | PubMed ID: 18518949 | Fulltext

Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development.

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Locke JB, Aziz RK, Vicknair MR, Nizet V, and Buchanan JT

PLoS ONE 3(7), 2008 - Who cited this? | PubMed ID: 18665241 | Fulltext

Recent advances in understanding the molecular basis of group B Streptococcus virulence.

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Maisey HC, Doran KS, and Nizet V

Expert reviews in molecular medicine 10, 2008 - Who cited this? | PubMed ID: 18803886 | Fulltext

CAMP factor is not essential for systemic virulence of Group B Streptococcus.

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Hensler ME, Quach D, Hsieh CJ, Doran KS, and Nizet V

Microbial pathogenesis 44(1):84-8, 2008 Jan - Who cited this? | PubMed ID: 17870297 | Fulltext

Role of the hypoxia inducible factors HIF in iron metabolism.

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Peyssonnau C, Nizet V, and Johnson RS

Cell cycle (Georgetown, Tex.) 7(1):28-32, 2008 Jan - Who cited this? | PubMed ID: 18212530 | Fulltext

Group B Streptococcal beta-Hemolysin/Cytolysin Directly Impairs Cardiomyocyte Viability and Function.

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Hensler ME, Miyamoto S, and Nizet V

PLoS ONE 3(6):e2446, 2008 - Who cited this? | PubMed ID: 18560574 | Fulltext

A Naturally Occurring Mutation in ropB Suppresses SpeB Expression and Reduces M1T1 Group A Streptococcal Systemic Virulence.

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Hollands A, Aziz RK, Kansal R, Kotb M, Nizet V, and Walker MJ

PLoS ONE 3(12):e4102, 2008 - Who cited this? | PubMed ID: 19116661 | Fulltext

Role of group A Streptococcus HtrA in the maturation of SpeB protease.

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Cole JN, Aquilina JA, Hains PG, Henningham A, Sriprakash KS, Caparon MG, Nizet V, Kotb M, Cordwell SJ, Djordjevic SP, and Walker MJ

Proteomics 7(24):4488, 2007 Dec - Who cited this? | PubMed ID: 18072207 | Fulltext

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