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Papers authored by Ng IO

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Targeting cadherin-17 inactivates Wnt signaling and inhibits tumor growth in liver carcinoma.

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Liu LX, Lee NP, Chan VW, Xue W, Zender L, Zhang C, Mao M, Dai H, Wang XL, Xu MZ, Lee TK, Ng IO, Chen Y, Kung HF, Lowe SW, Poon RT,

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Hepatology (Baltimore, Md.) 50(5):1453-63, 2009 Nov - Who cited this? | PubMed ID: 19676131 | Fulltext

MicroRNA expression, survival, and response to interferon in liver cancer.

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Ji J, Shi J, Budhu A, Yu Z, Forgues M, Roessler S, Ambs S, Chen Y, Meltzer PS, Croce CM, Qin LX, Man K, Lo CM, Lee J, Ng IO, Fan J,

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The New England journal of medicine 361(15):1437-47, 2009 Oct 8 - Who cited this? | PubMed ID: 19812400 | Fulltext

Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma.

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Xu MZ, Yao TJ, Lee NP, Ng IO, Chan YT, Zender L, Lowe SW, Poon RT, and Luk JM

Cancer 115(19):4576-85, 2009 Oct 1 - Who cited this? | PubMed ID: 19551889 | Fulltext

Liver cancer stem cells: implications for a new therapeutic target.

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Lee TK, Castilho A, Ma S, and Ng IO

Liver international : official journal of the International Association for the Study of the Liver 29(7):955-65, 2009 Aug - Who cited this? | PubMed ID: 19490415 | Fulltext

Association of BANK1 and TNFSF4 with systemic lupus erythematosus in Hong Kong Chinese.

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Chang YK, Yang W, Zhao M, Mok CC, Chan TM, Wong RW, Lee KW, Mok MY, Wong SN, Ng IO, Lee TL, Ho MH, Lee PP, Wong WH, Lau CS, Sham PC,

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Genes and immunity 10(5):414-20, 2009 Jul - Who cited this? | PubMed ID: 19357697 | Fulltext

Is histological diagnosis of primary liver carcinomas with fibrous stroma reproducible among experts?.

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Malouf G, Falissard B, Azoulay D, Callea F, Ferrell LD, Goodman ZD, Hayashi Y, Hsu HC, Hubscher SG, Kojiro M, Ng IO, Paterson AC, Reynes M, Zafrani ES, and Emile JF

Journal of clinical pathology 62(6):519-24, 2009 Jun - Who cited this? | PubMed ID: 19155239 | Fulltext

Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion.

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Wong CC, Wong CM, Tung EK, Man K, and Ng IO

Hepatology (Baltimore, Md.) 49(5):1583-94, 2009 May - Who cited this? | PubMed ID: 19205033 | Fulltext

Protein-losing enteropathy due to T-cell large granular lymphocyte leukemia.

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Hwang YY, Leung AY, Ng IO, Chan GS, Chan KW, Tse E, and Kwong YL

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(12):2097-8, 2009 Apr 20 - Who cited this? | PubMed ID: 19307498 | Fulltext

HAI-2 is epigenetically downregulated in human hepatocellular carcinoma, and its Kunitz domain type 1 is critical for anti-invasive functions.

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Tung EK, Wong CM, Yau TO, Lee JM, Ching YP, and Ng IO

International journal of cancer. Journal international du cancer 124(8):1811-9, 2009 Apr 15 - Who cited this? | PubMed ID: 19107935 | Fulltext

Role and significance of focal adhesion proteins in hepatocellular carcinoma.

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Yam JW, Tse EY, and Ng IO

Journal of gastroenterology and hepatology 24(4):520-30, 2009 Apr - Who cited this? | PubMed ID: 19368632 | Fulltext

Deleted in Liver Cancer 1 (DLC1) Utilizes a Novel Binding Site for Tensin2 PTB Domain Interaction and Is Required for Tumor-Suppressive Function.

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Chan LK, Ko FC, Ng IO, and Yam JW

PLoS ONE 4(5):e5572, 2009 - Who cited this? | PubMed ID: 19440389 | Fulltext

Deleted in liver cancer 2 (DLC2) was dispensable for development and its deficiency did not aggravate hepatocarcinogenesis.

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Yau TO, Leung TH, Lam S, Cheung OF, Tung EK, Khong PL, Lam A, Chung S, and Ng IO

PLoS ONE 4(8):e6566, 2009 - Who cited this? | PubMed ID: 19668331 | Fulltext

Role of a Novel Splice Variant of Mitotic Arrest Deficient 1 (MAD1), MAD1{beta}, in Mitotic Checkpoint Control in Liver Cancer.

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Sze KM, Ching YP, Jin DY, and Ng IO

Cancer research 68(22):9194-201, 2008 Nov 15 - Who cited this? | PubMed ID: 19010891 | Fulltext

Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells.

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Chan DW, Lee JM, Chan PC, and Ng IO

International journal of cancer. Journal international du cancer 123(5):1043, 2008 Sep 1 - Who cited this? | PubMed ID: 18553387 | Fulltext

Hepatitis B virus-associated multistep hepatocarcinogenesis: a stepwise increase in allelic alterations.

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Lee JM, Wong CM, and Ng IO

Cancer research 68(14):5988, 2008 Jul 15 - Who cited this? | PubMed ID: 18632655 | Fulltext

The significance of acute phase small-for-size graft injury on tumor growth and invasiveness after liver transplantation.

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Man K, Lo CM, Xiao JW, Ng KT, Sun BS, Ng IO, Cheng Q, Sun CK, and Fan ST

Annals of surgery 247(6):1049-57, 2008 Jun - Who cited this? | PubMed ID: 18520234 | Fulltext

Imaging features of hepatic angiomyolipomas.

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Low SC, Peh WC, Muttarak M, Cheung HS, and Ng IO

Journal of medical imaging and radiation oncology 52(2):118, 2008 Apr - Who cited this? | PubMed ID: 18373801 | Fulltext

Molecular pathogenesis of hepatocellular carcinoma.

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Wong CM and Ng IO

Liver international : official journal of the International Association for the Study of the Liver 28(2):160-74, 2008 Feb - Who cited this? | PubMed ID: 18069974 | Fulltext

Albumin mRNA in plasma predicts post-transplant recurrence of patients with hepatocellular carcinoma.

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Cheung ST, Fan ST, Lee YT, Chow JP, Ng IO, Fong DY, and Lo CM

Transplantation 85(1):81-7, 2008 Jan 15 - Who cited this? | PubMed ID: 18192916 | Fulltext

Deleted in Liver Cancer 1 (DLC1) Negatively Regulates Rho/ROCK/MLC Pathway in Hepatocellular Carcinoma.

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Wong CC, Wong CM, Ko FC, Chan LK, Ching YP, Yam JW, and Ng IO

PLoS ONE 3(7), 2008 - Who cited this? | PubMed ID: 18648664 | Fulltext

Gene expression profiles of different stages of hepatocarcinogenesis.

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Wong CC and Ng IO

Journal of gastroenterology and hepatology 23(1):1, 2008 Jan - Who cited this? | PubMed ID: 18171335 | Fulltext

Down-regulation of retinol binding protein 5 is associated with aggressive tumor features in hepatocellular carcinoma.

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Ho JC, Cheung ST, Poon WS, Lee YT, Ng IO, and Fan ST

Journal of cancer research and clinical oncology 133(12):929, 2007 Dec - Who cited this? | PubMed ID: 17497168 | Fulltext

A crucial role for dendritic cell (DC) IL-10 in inhibiting successful DC-based immunotherapy: superior antitumor immunity against hepatocellular carcinoma evoked by DC devoid of IL-10.

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Chen YX, Man K, Ling GS, Chen Y, Sun BS, Cheng Q, Wong OH, Lo CK, Ng IO, Chan LC, Lau GK, Lin CL, Huang F, and Huang FP

Journal of immunology (Baltimore, Md. : 1950) 179(9):6009-15, 2007 Nov 1 - Who cited this? | PubMed ID: 17947674 | Fulltext

Solution structures, dynamics, and lipid-binding of the sterile alpha-motif domain of the deleted in liver cancer 2.

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Li H, Fung KL, Jin DY, Chung SS, Ching YP, Ng IO, Sze KH, Ko BC, and Sun H

Proteins 67(4):1154-66, 2007 Jun 1 - Who cited this? | PubMed ID: 17380510 | Fulltext

A randomized, controlled trial of postoperative adjuvant interferon therapy after resection of hepatocellular carcinoma.

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Lo CM, Liu CL, Chan SC, Lam CM, Poon RT, Ng IO, Fan ST, and Wong J

Annals of surgery 245(6):831-42, 2007 Jun - Who cited this? | PubMed ID: 17522506 | Fulltext

Identification and characterization of tumorigenic liver cancer stem/progenitor cells.

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Ma S, Chan KW, Hu L, Lee TK, Wo JY, Ng IO, Zheng BJ, and Guan XY

Gastroenterology 132(7):2542-56, 2007 Jun - Who cited this? | PubMed ID: 17570225 | Fulltext

Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma.

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Wong CM, Ng YL, Lee JM, Wong CC, Cheung OF, Chan CY, Tung EK, Ching YP, and Ng IO

Hepatology (Baltimore, Md.) 45(5):1129-38, 2007 May - Who cited this? | PubMed ID: 17464989 | Fulltext

P21-activated protein kinase is overexpressed in hepatocellular carcinoma and enhances cancer metastasis involving c-Jun NH2-terminal kinase activation and paxillin phosphorylation.

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Ching YP, Leong VY, Lee MF, Xu HT, Jin DY, and Ng IO

Cancer research 67(8):3601-8, 2007 Apr 15 - Who cited this? | PubMed ID: 17440071 | Fulltext

Liver transplantation for combined hepatocellular cholangiocarcinoma.

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Chan AC, Lo CM, Ng IO, and Fan ST

Asian journal of surgery / Asian Surgical Association 30(2):143-6, 2007 Apr - Who cited this? | PubMed ID: 17475587 | Fulltext

The role of pathology and pathologists in the detection and management of cancer.

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Ng IO

Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine 13(1):5-7, 2007 Feb - Who cited this? | PubMed ID: 17277384 | Fulltext

Living donor versus deceased donor liver transplantation for early irresectable hepatocellular carcinoma.

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Lo CM, Fan ST, Liu CL, Chan SC, Ng IO, and Wong J

The British journal of surgery 94(1):78-86, 2007 Jan - Who cited this? | PubMed ID: 17016793 | Fulltext

Identification of carboxypeptidase of glutamate like-B as a candidate suppressor in cell growth and metastasis in human hepatocellular carcinoma.

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Zhang P, Chan DW, Zhu Y, Li JJ, Ng IO, Wan D, and Gu J

Clinical cancer research : an official journal of the American Association for Cancer Research 12(22):6617-25, 2006 Nov 15 - Who cited this? | PubMed ID: 17121880 | Fulltext

Osteomyelitis with proliferative periostitis: an unusual case.

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Tong AC, Ng IO, and Yeung KM

Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 102(5):e14-9, 2006 Nov - Who cited this? | PubMed ID: 17052617 | Fulltext

Signal transducers and activators of transcription 5b activation enhances hepatocellular carcinoma aggressiveness through induction of epithelial-mesenchymal transition.

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Lee TK, Man K, Poon RT, Lo CM, Yuen AP, Ng IO, Ng KT, Leonard W, and Fan ST

Cancer research 66(20):9948-56, 2006 Oct 15 - Who cited this? | PubMed ID: 17047057 | Fulltext

Tensin2 variant 3 is associated with aggressive tumor behavior in human hepatocellular carcinoma.

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Yam JW, Ko FC, Chan CY, Yau TO, Tung EK, Leung TH, Jin DY, and Ng IO

Hepatology (Baltimore, Md.) 44(4):881-90, 2006 Oct - Who cited this? | PubMed ID: 17006924 | Fulltext

Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer.

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Chan DW, Chan CY, Yam JW, Ching YP, and Ng IO

Gastroenterology 131(4):1218-27, 2006 Oct - Who cited this? | PubMed ID: 17030191 | Fulltext

Interaction of deleted in liver cancer 1 with tensin2 in caveolae and implications in tumor suppression.

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Yam JW, Ko FC, Chan CY, Jin DY, and Ng IO

Cancer research 66(17):8367-72, 2006 Sep 1 - Who cited this? | PubMed ID: 16951145 | Fulltext

Anterior approach versus conventional approach right hepatic resection for large hepatocellular carcinoma: a prospective randomized controlled study.

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Liu CL, Fan ST, Cheung ST, Lo CM, Ng IO, and Wong J

Annals of surgery 244(2):194-203, 2006 Aug - Who cited this? | PubMed ID: 16858181 | Fulltext

Knock-down of hepatitis B virus X protein reduces the tumorigenicity of hepatocellular carcinoma cells.

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Chan DW and Ng IO

The Journal of pathology 208(3):372-80, 2006 Feb - Who cited this? | PubMed ID: 16353167 | Fulltext

Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values.

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Luk JM, Lam CT, Siu AF, Lam BY, Ng IO, Hu MY, Che CM, and Fan ST

Proteomics 6(3):1049-57, 2006 Feb - Who cited this? | PubMed ID: 16400691 | Fulltext

Mitochondrial targeting of growth suppressor protein DLC2 through the START domain.

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Ng DC, Chan SF, Kok KH, Yam JW, Ching YP, Ng IO, and Jin DY

FEBS letters 580(1):191-8, 2006 Jan 9 - Who cited this? | PubMed ID: 16364308 | Fulltext

A randomized controlled study evaluating the safety and efficacy of deferiprone treatment in thalassemia major patients from Hong Kong.

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Ha SY, Chik KW, Ling SC, Lee AC, Luk CW, Lam CW, Ng IO, and Chan GC

Hemoglobin 30(2):263-74, 2006 - Who cited this? | PubMed ID: 16798652 | Fulltext

FTY720: a promising agent for treatment of metastatic hepatocellular carcinoma.

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Lee TK, Man K, Ho JW, Wang XH, Poon RT, Xu Y, Ng KT, Chu AC, Sun CK, Ng IO, Sun HC, Tang ZY, Xu R, and Fan ST

Clinical cancer research : an official journal of the American Association for Cancer Research 11(23):8458-66, 2005 Dec 1 - Who cited this? | PubMed ID: 16322309 | Fulltext

Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity.

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Leung TH, Ching YP, Yam JW, Wong CM, Yau TO, Jin DY, and Ng IO

Proceedings of the National Academy of Sciences of the United States of America 102(42):15207-12, 2005 Oct 18 - Who cited this? | PubMed ID: 16217026 | Fulltext

Rho GTPase-activating protein deleted in liver cancer suppresses cell proliferation and invasion in hepatocellular carcinoma.

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Wong CM, Yam JW, Ching YP, Yau TO, Leung TH, Jin DY, and Ng IO

Cancer research 65(19):8861-8, 2005 Oct 1 - Who cited this? | PubMed ID: 16204057 | Fulltext

Hepatic necroinflammation and fibrosis in patients with genotypes Ba and C, core-promoter and precore mutations.

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Yuen MF, Tanaka Y, Ng IO, Mizokami M, Yuen JC, Wong DK, Yuan HJ, Sum SM, Chan AO, and Lai CL

Journal of viral hepatitis 12(5):513-8, 2005 Sep - Who cited this? | PubMed ID: 16108767 | Fulltext

Tumor size predicts vascular invasion and histologic grade: Implications for selection of surgical treatment for hepatocellular carcinoma.

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Pawlik TM, Delman KA, Vauthey JN, Nagorney DM, Ng IO, Ikai I, Yamaoka Y, Belghiti J, Lauwers GY, Poon RT, and Abdalla EK

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 11(9):1086-92, 2005 Sep - Who cited this? | PubMed ID: 16123959 | Fulltext

Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil plus lamivudine.

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Lo CM, Liu CL, Lau GK, Chan SC, Ng IO, and Fan ST

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 11(7):807-13, 2005 Jul - Who cited this? | PubMed ID: 15973721 | Fulltext

Chimerism in transplant allografts.

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Ng IO

The British journal of surgery 92(6):661-2, 2005 Jun - Who cited this? | PubMed ID: 15912489 | Fulltext

Critical appraisal of the clinical and pathologic predictors of survival after resection of large hepatocellular carcinoma.

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Pawlik TM, Poon RT, Abdalla EK, Zorzi D, Ikai I, Curley SA, Nagorney DM, Belghiti J, Ng IO, Yamaoka Y, Lauwers GY, Vauthey JN, and International Cooperative Study Group on Hepatocellular Carcinoma

Archives of surgery (Chicago, Ill. : 1960) 140(5):450-7; discussion 457-8, 2005 May - Who cited this? | PubMed ID: 15897440 | Fulltext

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