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Papers authored by Nagase T

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KAP1-independent transcriptional repression of SCAN-KRAB-containing zinc finger proteins.

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Itokawa Y, Yanagawa T, Yamakawa H, Watanabe N, Koga H, and Nagase T

Biochemical and biophysical research communications 388(4):689-94, 2009 Oct 30 - Who cited this? | PubMed ID: 19695231 | Fulltext

Discovery of a series of acrylic acids and their derivatives as chemical leads for selective EP3 receptor antagonists.

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Asada M, Obitsu T, Nagase T, Sugimoto I, Yamaura Y, Sato K, Narita M, Ohuchida S, Nakai H, and Toda M

Bioorganic & medicinal chemistry 17(18):6567-82, 2009 Sep 15 - Who cited this? | PubMed ID: 19700331 | Fulltext

Ultrasonographic and thermographic screening for latent inflammation in diabetic foot callus.

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Nishide K, Nagase T, Oba M, Oe M, Ohashi Y, Iizaka S, Nakagami G, Kadowaki T, and Sanada H

Diabetes research and clinical practice 85(3):304-9, 2009 Sep - Who cited this? | PubMed ID: 19586674 | Fulltext

Identification and characterization of a selective radioligand for ELOVL6.

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Shimamura K, Takahashi H, Kitazawa H, Miyamoto Y, Nagumo A, Tang C, Dean D, Nagase T, Sato N, and Tokita S

Journal of biochemistry 146(3):429-37, 2009 Sep - Who cited this? | PubMed ID: 19505953 | Fulltext

Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice.

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Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, and Kurihara H

American journal of respiratory and critical care medicine 180(4):326-38, 2009 Aug 15 - Who cited this? | PubMed ID: 19498055 | Fulltext

Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor.

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Ando M, Sato N, Nagase T, Nagai K, Ishikawa S, Takahashi H, Ohtake N, Ito J, Hirayama M, Mitobe Y, Iwaasa H, Gomori A, Matsushita H, Tadano K, Fujino N, Tanaka S,

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Bioorganic & medicinal chemistry 17(16):6106-22, 2009 Aug 15 - Who cited this? | PubMed ID: 19616955 | Fulltext

Hyperoxia exaggerates bacterial dissemination and lethality in Pseudomonas aeruginosa pneumonia.

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Kikuchi Y, Tateda K, Fuse ET, Matsumoto T, Gotoh N, Fukushima J, Takizawa H, Nagase T, Standiford TJ, and Yamaguchi K

Pulmonary pharmacology & therapeutics 22(4):333-9, 2009 Aug - Who cited this? | PubMed ID: 19162211 | Fulltext

Synthesis, structure-activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H(3) receptor inverse agonists.

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Sasaki T, Takahashi T, Nagase T, Mizutani T, Ito S, Mitobe Y, Miyamoto Y, Kanesaka M, Yoshimoto R, Tanaka T, Takenaga N, Tokita S, and Sato N

Bioorganic & medicinal chemistry letters 19(15):4232-6, 2009 Aug 1 - Who cited this? | PubMed ID: 19520574 | Fulltext

Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.

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Mitobe Y, Ito S, Mizutani T, Nagase T, Sato N, and Tokita S

Bioorganic & medicinal chemistry letters 19(15):4075-8, 2009 Aug 1 - Who cited this? | PubMed ID: 19553110 | Fulltext

Synthesis and evaluation of a novel 2-azabicyclo[2.2.2]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

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Sasaki T, Nagase T, Takahashi T, Nagumo A, Shimamura K, Miyamoto Y, Kitazawa H, Kanesaka M, Yoshimoto R, Aragane K, Tokita S, and Sato N

Bioorganic & medicinal chemistry 17(15):5639-47, 2009 Aug 1 - Who cited this? | PubMed ID: 19596583 | Fulltext

Ribavirin dose reduction raises relapse rate dose-dependently in genotype 1 patients with hepatitis C responding to pegylated interferon alpha-2b plus ribavirin.

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Hiramatsu N, Oze T, Yakushijin T, Inoue Y, Igura T, Mochizuki K, Imanaka K, Kaneko A, Oshita M, Hagiwara H, Mita E, Nagase T, Ito T, Inui Y, Hijioka T, Katayama K,

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Journal of viral hepatitis 16(8):586-94, 2009 Aug - Who cited this? | PubMed ID: 19552664 | Fulltext

Synthesis and biological evaluation of a novel 3-sulfonyl-8-azabicyclo[3.2.1]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

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Nagase T, Takahashi T, Sasaki T, Nagumo A, Shimamura K, Miyamoto Y, Kitazawa H, Kanesaka M, Yoshimoto R, Aragane K, Tokita S, and Sato N

Journal of medicinal chemistry 52(14):4111-4, 2009 Jul 23 - Who cited this? | PubMed ID: 19522500 | Fulltext

5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a Potent Inhibitor for Mammalian Elongase of Long-Chain Fatty Acids Family 6: Examination of Its Potential Utility as a Pharmacological Tool.

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Shimamura K, Kitazawa H, Miyamoto Y, Kanesaka M, Nagumo A, Yoshimoto R, Aragane K, Morita N, Ohe T, Takahashi T, Nagase T, Sato N, and Tokita S

The Journal of pharmacology and experimental therapeutics 330(1):249-56, 2009 Jul - Who cited this? | PubMed ID: 19359527 | Fulltext

A selective small molecule glucagon-like peptide-1 secretagogue acting via depolarization-coupled Ca(2+) influx.

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Eiki J, Saeki K, Nagano N, Iino T, Yonemoto M, Takayenoki-Iino Y, Ito S, Nishimura T, Sato Y, Bamba M, Watanabe H, Sasaki K, Ohyama S, Kanatani A, Nagase T, and Yada T

The Journal of endocrinology 201(3):361-7, 2009 Jun - Who cited this? | PubMed ID: 19332449 | Fulltext

Synthesis and evaluation of a novel indoledione class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

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Takahashi T, Nagase T, Sasaki T, Nagumo A, Shimamura K, Miyamoto Y, Kitazawa H, Kanesaka M, Yoshimoto R, Aragane K, Tokita S, and Sato N

Journal of medicinal chemistry 52(10):3142-5, 2009 May 28 - Who cited this? | PubMed ID: 19388647 | Fulltext

Pericellular matrix of decidua-derived mesenchymal cells: A potent human-derived substrate for the maintenance culture of human ES cells.

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Nagase T, Ueno M, Matsumura M, Muguruma K, Ohgushi M, Kondo N, Kanematsu D, Kanemura Y, and Sasai Y

Developmental dynamics : an official publication of the American Association of Anatomists 238(5):1118-30, 2009 May - Who cited this? | PubMed ID: 19384957 | Fulltext

Thyroid Transcription Factor-1 Inhibits Transforming Growth Factor-{beta}-Mediated Epithelial-to-Mesenchymal Transition in Lung Adenocarcinoma Cells.

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Saito RA, Watabe T, Horiguchi K, Kohyama T, Saitoh M, Nagase T, and Miyazono K

Cancer research 69(7):2783-91, 2009 Apr 1 - Who cited this? | PubMed ID: 19293183 | Fulltext

C-reactive protein modulates human lung fibroblast migration.

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Kikuchi K, Kohyama T, Yamauchi Y, Kato J, Takami K, Okazaki H, Desaki M, Nagase T, Rennard SI, and Takizawa H

Experimental lung research 35(1):48-58, 2009 Feb - Who cited this? | PubMed ID: 19191104 | Fulltext

Eicosapentaenoic acid inhibits voltage-gated sodium channels and invasiveness in prostate cancer cells.

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Nakajima T, Kubota N, Tsutsumi T, Oguri A, Imuta H, Jo T, Oonuma H, Soma M, Meguro K, Takano H, Nagase T, and Nagata T

British journal of pharmacology 156(3):420-31, 2009 Feb - Who cited this? | PubMed ID: 19154441 | Fulltext

The insulin ball.

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Nagase T, Katsura Y, Iwaki Y, Nemoto K, Sekine H, Miwa K, Oh-I T, Kou K, Iwaya K, Noritake M, and Matsuoka T

Lancet 373(9658):184, 2009 Jan 10 - Who cited this? | PubMed ID: 19135614 | Fulltext

Factors contributing to antiviral effect of adefovir dipivoxil therapy added to ongoing lamivudine treatment in patients with lamivudine-resistant chronic hepatitis B.

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Kurashige N, Hiramatsu N, Ohkawa K, Yakushijin T, Kiso S, Kanto T, Takehara T, Kasahara A, Doi Y, Yamada A, Oshita M, Mita E, Hagiwara H, Nagase T, Yoshihara H, Hayashi E,

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Journal of gastroenterology 44(6):601-7, 2009 - Who cited this? | PubMed ID: 19387534 | Fulltext

Lamivudine-to-entecavir switching treatment in type B chronic hepatitis patients without evidence of lamivudine resistance.

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Kurashige N, Ohkawa K, Hiramatsu N, Yakushijin T, Mochizuki K, Oze T, Kiso S, Kanto T, Takehara T, Kasahara A, Doi Y, Yamada A, Fukuda K, Oshita M, Mita E, Fukui H,

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Journal of gastroenterology 44(8):864-70, 2009 - Who cited this? | PubMed ID: 19475333 | Fulltext

Pulse-chase experiment for the analysis of protein stability in cultured Mammalian cells by covalent fluorescent labeling of fusion proteins.

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Yamaguchi K, Inoue S, Ohara O, and Nagase T

Methods in molecular biology (Clifton, N.J.) 577:121-31, 2009 - Who cited this? | PubMed ID: 19718513 | Fulltext

Development of novel 2-[4-(aminoalkoxy)phenyl]-4(3H)-quinazolinone derivatives as potent and selective histamine H(3) receptor inverse agonists.

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Mizutani T, Nagase T, Ito S, Miyamoto Y, Tanaka T, Takenaga N, Tokita S, and Sato N

Bioorganic & medicinal chemistry letters 18(23):6041-5, 2008 Dec 1 - Who cited this? | PubMed ID: 18952421 | Fulltext

Synthesis and evaluation of structurally constrained quinazolinone derivatives as potent and selective histamine h3 receptor inverse agonists.

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Nagase T, Mizutani T, Sekino E, Ishikawa S, Ito S, Mitobe Y, Miyamoto Y, Yoshimoto R, Tanaka T, Ishihara A, Takenaga N, Tokita S, and Sato N

Journal of medicinal chemistry 51(21):6889-901, 2008 Nov 13 - Who cited this? | PubMed ID: 18841880 | Fulltext

Chronic obstructive pulmonary disease (COPD).

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Nagase T

Nippon Ronen Igakkai zasshi. Japanese journal of geriatrics 45(5):479-81, 2008 Sep - Who cited this? | PubMed ID: 19057095 | Fulltext

Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine h3 receptor inverse agonists.

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Nagase T, Mizutani T, Ishikawa S, Sekino E, Sasaki T, Fujimura T, Ito S, Mitobe Y, Miyamoto Y, Yoshimoto R, Tanaka T, Ishihara A, Takenaga N, Tokita S, Fukami T, and Sato N

Journal of medicinal chemistry 51(15):4780-9, 2008 Aug 14 - Who cited this? | PubMed ID: 18598020 | Fulltext

Clarithromycin inhibits fibroblast migration.

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Kohyama T, Yamauchi Y, Takizawa H, Itakura S, Kamitani S, Kato J, and Nagase T

Respiratory medicine, 2008 Aug 11 - Who cited this? | PubMed ID: 18701271 | Fulltext

The Novel Protein Complex with SMARCAD1/KIAA1122 Binds to the Vicinity of TSS.

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Okazaki N, Ikeda S, Ohara R, Shimada K, Yanagawa T, Nagase T, Ohara O, and Koga H

Journal of molecular biology, 2008 Jul 17 - Who cited this? | PubMed ID: 18675275 | Fulltext

Sequential and quantitative analysis of a murine model of elastase-induced emphysema.

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Kawakami M, Matsuo Y, Yoshiura K, Nagase T, and Yamashita N

Biological & pharmaceutical bulletin 31(7):1434-8, 2008 Jul - Who cited this? | PubMed ID: 18591788 | Fulltext

Exploration of Human ORFeome: High-Throughput Preparation of ORF Clones and Efficient Characterization of Their Protein Products.

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Nagase T, Yamakawa H, Tadokoro S, Nakajima D, Inoue S, Yamaguchi K, Itokawa Y, Kikuno RF, Koga H, and Ohara O

DNA research : an international journal for rapid publication of reports on genes and genomes 15(3):137, 2008 Jun 30 - Who cited this? | PubMed ID: 18316326 | Fulltext

Evidence for fractional crystallization of wadsleyite and ringwoodite from olivine melts in chondrules entrained in shock-melt veins.

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Miyahara M, El Goresy A, Ohtani E, Nagase T, Nishijima M, Vashaei Z, Ferroir T, Gillet P, Dubrovinsky L, and Simionovici A

Proceedings of the National Academy of Sciences of the United States of America 105(25):8542, 2008 Jun 24 - Who cited this? | PubMed ID: 18562280 | Fulltext

Comparison of mesenchymal tissues-derived stem cells for in vivo chondrogenesis: suitable conditions for cell therapy of cartilage defects in rabbit.

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Koga H, Muneta T, Nagase T, Nimura A, Ju YJ, Mochizuki T, and Sekiya I

Cell and tissue research, 2008 Jun 17 - Who cited this? | PubMed ID: 18560897 | Fulltext

Effect of dexamethasone on voltage-gated Na(+) channel in cultured human bronchial smooth muscle cells.

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Nakajima T, Jo T, Meguro K, Oonuma H, Ma J, Kubota N, Imuta H, Takano H, Iida H, Nagase T, and Nagata T

Life sciences 82(23-24):1210-5, 2008 Jun 4 - Who cited this? | PubMed ID: 18485418 | Fulltext

Bridging the gap from frog research to human therapy: a tale of neural differentiation in Xenopus animal caps and human pluripotent cells.

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Sasai Y, Ogushi M, Nagase T, and Ando S

Development, growth & differentiation 50 Suppl 1:S47-55, 2008 Jun - Who cited this? | PubMed ID: 18494707 | Fulltext

Analysis of the chondrogenic potential of human synovial stem cells according to harvest site and culture parameters in knees with medial compartment osteoarthritis.

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Nagase T, Muneta T, Ju YJ, Hara K, Morito T, Koga H, Nimura A, Mochizuki T, and Sekiya I

Arthritis and rheumatism 58(5):1389-98, 2008 May - Who cited this? | PubMed ID: 18438859 | Fulltext

Smurf1 directly targets hPEM-2, a GEF for Cdc42, via a novel combination of protein interaction modules in the ubiquitin-proteasome pathway.

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Yamaguchi K, Ohara O, Ando A, and Nagase T

Biological chemistry 389(4):405, 2008 Apr - Who cited this? | PubMed ID: 18208356 | Fulltext

A genetic linkage map of the house musk shrew, Suncus murinus, Constructed with PCR-based and RFLP markers.

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Adjei S, Sato A, Nagase T, Matsubara K, Matsuda Y, Namikawa T, and Ishikawa A

Experimental animals / Japanese Association for Laboratory Animal Science 57(2):129, 2008 Apr - Who cited this? | PubMed ID: 18421175 | Fulltext

Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.

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Makita R, Uchijima Y, Nishiyama K, Amano T, Chen Q, Takeuchi T, Mitani A, Nagase T, Yatomi Y, Aburatani H, Nakagawa O, Small EV, Cobo-Stark P, Igarashi P, Murakami M, Tominaga J,

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American journal of physiology. Renal physiology 294(3):F542-53, 2008 Mar - Who cited this? | PubMed ID: 18172001 | Fulltext

Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42.

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Ueda H, Nagae R, Kozawa M, Morishita R, Kimura S, Nagase T, Ohara O, Yoshida S, and Asano T

The Journal of biological chemistry 283(4):1946, 2008 Jan 25 - Who cited this? | PubMed ID: 18045877 | Fulltext

Non-infectious bronchiolitis as an early pulmonary complication of hematopoietic stem cell transplantation.

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Kage H, Kohyama T, Kitagawa H, Takai D, Kanda Y, Ohishi N, and Nagase T

Internal medicine (Tokyo, Japan) 47(1):61, 2008 - Who cited this? | PubMed ID: 18176008 | Fulltext

Hedgehog signalling in vascular development.

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Nagase T, Nagase M, Machida M, and Fujita T

Angiogenesis 11(1):71, 2008 - Who cited this? | PubMed ID: 18301996 | Fulltext

Essential elements in the coding region of mRNA for translation of ColE2 Rep protein.

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Nagase T, Nishio S, and Itoh T

Plasmid 59(1):36-44, 2008 Jan - Who cited this? | PubMed ID: 18061669 | Fulltext

Rapid 3-dimensional imaging of embryonic craniofacial morphology using microscopic computed tomography.

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Nagase T, Sasazaki Y, Kikuchi T, and Machida M

Journal of computer assisted tomography 32(5):816-21, 2008 - Who cited this? | PubMed ID: 18830118 | Fulltext

Importance of the leader region of mRNA for translation initiation of ColE2 Rep protein.

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Nagase T, Nishio SY, and Itoh T

Plasmid 58(3):249-60, 2007 Nov - Who cited this? | PubMed ID: 17720244 | Fulltext

Calcitonin gene-related peptide mediates acid-induced lung injury in mice.

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Aoki-Nagase T, Nagase T, Oh-Hashi Y, Kurihara Y, Yamaguchi Y, Yamamoto H, Nagata T, Kurihara H, and Ouchi Y

Respirology (Carlton, Vic.) 12(6):807-13, 2007 Nov - Who cited this? | PubMed ID: 17986107 | Fulltext

A second-generation profiling system for quantitative methylation analysis of multiple gene promoters: application to lung cancer.

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Sano A, Kage H, Sugimoto K, Kitagawa H, Aki N, Goto A, Fukayama M, Nakajima J, Takamoto S, Nagase T, Yatomi Y, Ohishi N, and Takai D

Oncogene 26(45):6518-25, 2007 Oct 4 - Who cited this? | PubMed ID: 17452971 | Fulltext

Ultrasonographic evaluation of an unusual peri-anal induration: a possible case of deep tissue injury.

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Nagase T, Koshima I, Maekawa T, Kaneko J, Sugawara Y, Makuuchi M, Koyanagi H, Nakagami G, and Sanada H

Journal of wound care 16(8):365-7, 2007 Sep - Who cited this? | PubMed ID: 17927084 | Fulltext

[Clinical management of the aged patients with COPD].

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Nagase T

Nippon Ronen Igakkai zasshi. Japanese journal of geriatrics 44(5):585-6, 2007 Sep - Who cited this? | PubMed ID: 18049002 | Fulltext

The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus.

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Sugimoto K, Kage H, Aki N, Sano A, Kitagawa H, Nagase T, Yatomi Y, Ohishi N, and Takai D

Biochemical and biophysical research communications 359(3):497-502, 2007 Aug 3 - Who cited this? | PubMed ID: 17544373 | Fulltext

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