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Papers authored by Nagabhushan TL

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Enhancement of intravesical delivery with Syn3 potentiates interferon-alpha2b gene therapy for superficial bladder cancer.

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Nagabhushan TL, Maneval DC, Benedict WF, Wen SF, Ihnat PM, Engler H, and Connor RJ

Cytokine & growth factor reviews 18(5-6):389-94, 2007 - Who cited this? | PubMed ID: 17692556 | Fulltext

Inhibitors of farnesyl protein transferase and MEK1,2 induce apoptosis in fibroblasts transformed with farnesylated but not geranylgeranylated H-Ras.

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Brassard DL, English JM, Malkowski M, Kirschmeier P, Nagabhushan TL, and Bishop WR

Experimental cell research 273(2):138-46, 2002 Feb 15 - Who cited this? | PubMed ID: 11822869 | Fulltext

Interferon alpha2b gene delivery using adenoviral vector causes inhibition of tumor growth in xenograft models from a variety of cancers.

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Iqbal Ahmed CM, Johnson DE, Demers GW, Engler H, Howe JA, Wills KN, Wen SF, Shinoda J, Beltran J, Nodelman M, Machemer T, Maneval DC, Nagabhushan TL, and Sugarman BJ

Cancer gene therapy 8(10):788-95, 2001 Oct - Who cited this? | PubMed ID: 11687902 | Fulltext

Selective expression of nonsecreted interferon by an adenoviral vector confers antiproliferative and antiviral properties and causes reduction of tumor growth in nude mice.

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Ahmed CM, Wills KN, Sugarman BJ, Johnson DE, Ramachandra M, Nagabhushan TL, and Howe JA

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 21(6):399-408, 2001 Jun - Who cited this? | PubMed ID: 11440637 | Fulltext

Identification of polyamides that enhance adenovirus-mediated gene expression in the urothelium.

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Connor RJ, Engler H, Machemer T, Philopena JM, Horn MT, Sutjipto S, Maneval DC, Youngster S, Chan TM, Bausch J, McAuliffe JP, Hindsgaul O, and Nagabhushan TL

Gene therapy 8(1):41-8, 2001 Jan - Who cited this? | PubMed ID: 11402300 | Fulltext

Design, characterization, and structure of a biologically active single-chain mutant of human IFN-gamma.

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Landar A, Curry B, Parker MH, DiGiacomo R, Indelicato SR, Nagabhushan TL, Rizzi G, and Walter MR

Journal of molecular biology 299(1):169-79, 2000 May 26 - Who cited this? | PubMed ID: 10860730 | Fulltext

Design and analysis of an engineered human interleukin-10 monomer.

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Josephson K, DiGiacomo R, Indelicato SR, Iyo AH, Nagabhushan TL, Parker MH, and Walter MR

The Journal of biological chemistry 275(18):13552-7, 2000 May 5 - Who cited this? | PubMed ID: 10788470 | Fulltext

Extraction and characterization of adenovirus proteins from sodium dodecylsulfate polyacrylamide gel electrophoresis by matrix-assisted laser desorption/ionization mass spectrometry.

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Mirza UA, Liu YH, Tang JT, Porter F, Bondoc L, Chen G, Pramanik BN, and Nagabhushan TL

Journal of the American Society for Mass Spectrometry 11(4):356-61, 2000 Apr - Who cited this? | PubMed ID: 10757173 | Fulltext

Mass spectrometric mapping of disulfide bonds in recombinant human interleukin-13.

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Tsarbopoulos A, Varnerin J, Cannon-Carlson S, Wylie D, Pramanik B, Tang J, and Nagabhushan TL

Journal of mass spectrometry : JMS 35(3):446-53, 2000 Mar - Who cited this? | PubMed ID: 10767776 | Fulltext

Integrin alpha(v)beta(3)-mediated activation of apoptosis.

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Brassard DL, Maxwell E, Malkowski M, Nagabhushan TL, Kumar CC, and Armstrong L

Experimental cell research 251(1):33-45, 1999 Aug 25 - Who cited this? | PubMed ID: 10438569 | Fulltext

In vivo tumor suppression by adenovirus-mediated interferon alpha2b gene delivery.

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Ahmed CM, Sugarman BJ, Johnson DE, Bookstein RE, Saha DP, Nagabhushan TL, and Wills KN

Human gene therapy 10(1):77-84, 1999 Jan 1 - Who cited this? | PubMed ID: 10022532 | Fulltext

Biological properties of recombinant alpha-interferons: 40th anniversary of the discovery of interferons.

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Pfeffer LM, Dinarello CA, Herberman RB, Williams BR, Borden EC, Bordens R, Walter MR, Nagabhushan TL, Trotta PP, and Pestka S

Cancer research 58(12):2489-99, 1998 Jun 15 - Who cited this? | PubMed ID: 9635566 | Fulltext

Review of recent developments in the molecular characterization of recombinant alfa interferons on the 40th anniversary of the discovery of interferon.

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Walter MR, Bordens R, Nagabhushan TL, Williams BR, Herberman RB, Dinarello CA, Borden EC, Trotta PP, Pestka S, and Pfeffer LM

Cancer biotherapy & radiopharmaceuticals 13(3):143-54, 1998 Jun - Who cited this? | PubMed ID: 10850350 | Fulltext

Molecular and biologic characterization of recombinant interferon-alpha2b.

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Bordens R, Grossberg SE, Trotta PP, and Nagabhushan TL

Seminars in oncology 24(3 Suppl 9):S9-41-S9-51, 1997 Jun - Who cited this? | PubMed ID: 9208872 | Fulltext

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography.

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Radhakrishnan R, Walter LJ, Hruza A, Reichert P, Trotta PP, Nagabhushan TL, and Walter MR

Structure (London, England : 1993) 4(12):1453-63, 1996 Dec 15 - Who cited this? | PubMed ID: 8994971 | Fulltext

Purification and crystallization of a complex between human interferon gamma receptor (extracellular domain) and human interferon gamma.

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Windsor WT, Walter LJ, Syto R, Fossetta J, Cook WJ, Nagabhushan TL, and Walter MR

Proteins 26(1):108-14, 1996 Sep - Who cited this? | PubMed ID: 8880934 | Fulltext

Structure and humanization of a rat monoclonal Fab to human interleukin-5.

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Cook WJ, Walter LJ, Murgolo NJ, Chou CC, Petro M, Zavodny PJ, Narula SK, Ramanathan L, Trotta PP, and Nagabhushan TL

Protein engineering 9(7):623-8, 1996 Jul - Who cited this? | PubMed ID: 8844835 | Fulltext

Crystal structure of interleukin 10 reveals an interferon gamma-like fold.

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Walter MR and Nagabhushan TL

Biochemistry 34(38):12118-25, 1995 Sep 26 - Who cited this? | PubMed ID: 7547951 | Fulltext

Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor.

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Walter MR, Windsor WT, Nagabhushan TL, Lundell DJ, Lunn CA, Zauodny PJ, and Narula SK

Nature 376(6537):230-5, 1995 Jul 20 - Who cited this? | PubMed ID: 7617032 | Fulltext

Crystallization and preliminary X-ray investigation of recombinant human interleukin 10.

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Cook WJ, Windsor WT, Murgolo NJ, Tindall SH, Nagabhushan TL, and Walter MR

Proteins 22(2):187-90, 1995 Jun - Who cited this? | PubMed ID: 7567966 | Fulltext

Mass spectrometric identification of a naturally processed melanoma peptide recognized by CD8+ cytotoxic T lymphocytes.

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Castelli C, Storkus WJ, Maeurer MJ, Martin DM, Huang EC, Pramanik BN, Nagabhushan TL, Parmiani G, and Lotze MT

The Journal of experimental medicine 181(1):363-8, 1995 Jan 1 - Who cited this? | PubMed ID: 7807017 | Fulltext

Comparative mapping of recombinant proteins and glycoproteins by plasma desorption and matrix-assisted laser desorption/ionization mass spectrometry.

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Tsarbopoulos A, Karas M, Strupat K, Pramanik BN, Nagabhushan TL, and Hillenkamp F

Analytical chemistry 66(13):2062-70, 1994 Jul 1 - Who cited this? | PubMed ID: 8067523 | Fulltext

Isolation and characterization of a resistant core peptide of recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF); confirmation of the GM-CSF amino acid sequence by mass spectrometry.

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Tsarbopoulos A, Pramanik BN, Labdon JE, Reichert P, Gitlin G, Patel S, Sardana V, Nagabhushan TL, and Trotta PP

Protein science : a publication of the Protein Society 2(11):1948-58, 1993 Nov - Who cited this? | PubMed ID: 8268804 | Fulltext

Crystal structure of recombinant human interleukin-4.

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Walter MR, Cook WJ, Zhao BG, Cameron RP, Ealick SE, Walter RL, Reichert P, Nagabhushan TL, Trotta PP, and Bugg CE

The Journal of biological chemistry 267(28):20371-6, 1992 Oct 5 - Who cited this? | PubMed ID: 1400355 | Fulltext

Application of plasma desorption mass spectrometry to molecular weight determination of human interleukin-4 secreted by a Chinese hamster ovary line.

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Tsarbopoulos A, Her GR, Pramanik BN, Trotta PP, and Nagabhushan TL

Analytical chemistry 64(19):2303-5, 1992 Oct 1 - Who cited this? | PubMed ID: 1449214 | Fulltext

Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor.

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Walter MR, Cook WJ, Ealick SE, Nagabhushan TL, Trotta PP, and Bugg CE

Journal of molecular biology 224(4):1075-85, 1992 Apr 20 - Who cited this? | PubMed ID: 1569568 | Fulltext

Three-dimensional structure of recombinant human interferon-gamma.

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Ealick SE, Cook WJ, Vijay-Kumar S, Carson M, Nagabhushan TL, Trotta PP, and Bugg CE

Science (New York, N.Y.) 252(5006):698-702, 1991 May 3 - Who cited this? | PubMed ID: 1902591 | Fulltext

Crystallization and preliminary X-ray investigation of recombinant human interleukin 4.

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Cook WJ, Ealick SE, Reichert P, Hammond GS, Le HV, Nagabhushan TL, Trotta PP, and Bugg CE

Journal of molecular biology 218(4):675-8, 1991 Apr 20 - Who cited this? | PubMed ID: 2023241 | Fulltext

252Cf-plasma desorption and cesium-ion liquid secondary-ion mass spectrometric analysis of recombinant proteins.

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Tsarbopoulos A, Pramanik BN, Reichert P, Siegel MM, Nagabhushan TL, and Trotta PP

Rapid communications in mass spectrometry : RCM 5(2):81-5, 1991 Feb - Who cited this? | PubMed ID: 1804408 | Fulltext

Structural analysis of biologically active peptides and recombinant proteins and their modified counterparts by mass spectrometry.

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Pramanik BN, Tsarbopoulos A, Labdon JE, Trotta PP, and Nagabhushan TL

Journal of chromatography 562(1-2):377-89, 1991 Jan 2 - Who cited this? | PubMed ID: 2026704 | Fulltext

Crystallization and preliminary x-ray investigation of recombinant human granulocyte-macrophage colony-stimulating factor.

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Reichert P, Cook WJ, Ealick SE, Hammond GS, Le HV, Nagabhushan TL, Trotta PP, and Bugg CE

The Journal of biological chemistry 265(1):452-3, 1990 Jan 5 - Who cited this? | PubMed ID: 2403563 | Fulltext

Multiple forms of recombinant murine interleukin-4 expressed in COS-7 monkey kidney cells.

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Ramanathan L, Le HV, Labdon JE, Mays-Ichinco CA, Syto R, Arai N, Nagabhushan TL, and Trotta PP

Biochimica et biophysica acta 1007(3):283-8, 1989 Apr 12 - Who cited this? | PubMed ID: 2784692 | Fulltext

Demonstration of a 1-3 disulfide bond in a synthetic nonapeptide derived from the signal sequence and N-terminus of human gamma-interferon.

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Pramanik B, Tsarbopoulos A, Labdon JE, Czarniecki M, Nagabhushan TL, and Trotta PP

Biochemical and biophysical research communications 157(2):836-43, 1988 Dec 15 - Who cited this? | PubMed ID: 3144280 | Fulltext

Purification and properties of a novel recombinant human hybrid interferon, delta-4 alpha 2/alpha 1.

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Le HV, Syto R, Schwartz J, Nagabhushan TL, and Trotta PP

Biochimica et biophysica acta 957(1):143-51, 1988 Nov 2 - Who cited this? | PubMed ID: 3052593 | Fulltext

Isolation and characterization of multiple variants of recombinant human interleukin 4 expressed in mammalian cells.

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Le HV, Ramanathan L, Labdon JE, Mays-Ichinco CA, Syto R, Arai N, Hoy P, Takebe Y, Nagabhushan TL, and Trotta PP

The Journal of biological chemistry 263(22):10817-23, 1988 Aug 5 - Who cited this? | PubMed ID: 3260592 | Fulltext

Evidence for a polypeptide segment at the carboxyl terminus of recombinant human gamma interferon involved in expression of biological activity.

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Seelig GF, Wijdenes J, Nagabhushan TL, and Trotta PP

Biochemistry 27(6):1981-7, 1988 Mar 22 - Who cited this? | PubMed ID: 3132204 | Fulltext

Crystallization and preliminary X-ray investigation of a recombinant form of human gamma-interferon.

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Vijay-Kumar S, Senadhi SE, Ealick SE, Nagabhushan TL, Trotta PP, Kosecki R, Reichert P, and Bugg CE

The Journal of biological chemistry 262(10):4804-5, 1987 Apr 5 - Who cited this? | PubMed ID: 3104324 | Fulltext

Immunochemical mapping of alpha-2 interferon.

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Lydon NB, Favre C, Bove S, Neyret O, Benureau S, Levine AM, Seelig GF, Nagabhushan TL, and Trotta PP

Biochemistry 24(15):4131-41, 1985 Jul 16 - Who cited this? | PubMed ID: 2413884 | Fulltext

Mechanisms of fever induced by recombinant human interferon.

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Dinarello CA, Bernheim HA, Duff GW, Le HV, Nagabhushan TL, Hamilton NC, and Coceani F

The Journal of clinical investigation 74(3):906-13, 1984 Sep - Who cited this? | PubMed ID: 6590569 | Fulltext

Carbocyclic arabinofuranosyladenine (cyclaradine): efficacy against genital herpes in guinea pigs.

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Vince R, Daluge S, Lee H, Shannon WM, Arnett G, Schafer TW, Nagabhushan TL, Reichert P, and Tsai H

Science (New York, N.Y.) 221(4618):1405-6, 1983 Sep 30 - Who cited this? | PubMed ID: 6684328 | Fulltext

Some recent advances in the chemistry of antibiotics of the gentamicin series.

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Daniels PJ, Cooper AB, McCombie SW, Nagabhushan TL, Rane DF, and Wright JJ

The Japanese journal of antibiotics 32 Suppl:S195-204, 1979 Dec - Who cited this? | PubMed ID: 398903 | Fulltext

Biosynthetic pathway leading to gentamicin C2b.

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Lee BK, Nagabhushan TL, Condon RG, Shimonaski G, Kalyanpur MG, Patel M, and Waitz JA

Antimicrobial agents and chemotherapy 16(5):589-91, 1979 Nov - Who cited this? | PubMed ID: 525999 | Fulltext

Antibiotic biosynthesis by cofermentation of blocked mutants of two Micromonospora species.

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Lee BK, Nagabhushan TL, Condon RG, Cooper AB, and Waitz JA

Antimicrobial agents and chemotherapy 14(1):73-7, 1978 Jul - Who cited this? | PubMed ID: 686710 | Fulltext

The syntheses and biological properties of 1-N-(S-4-amino-2-hydroxybutyryl)-gentamicin B and 1-N-(S-3-amino-2-hydroxypropionyl)-gentamicin B.

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Nagabhushan TL, Cooper AB, Tsai H, Daniels PJ, and Miller GH

The Journal of antibiotics 31(7):681-7, 1978 Jul - Who cited this? | PubMed ID: 690003 | Fulltext

Selective N-actylation of gentamicin antibiotics-synthesis of 1-N-acyl derivatives.

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Wright JJ, Cooper A, Daniels PJ, Nagabhushan TL, Rane D, Turner WN, and Weinstein J

The Journal of antibiotics 29(7):714-9, 1976 Jul - Who cited this? | PubMed ID: 8416 | Fulltext

The structure of antibiotic G-52, a new aminocyclitol-aminoglycoside antibiotic produced by Micromonospora zionensis.

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Daniels PJ, Jaret RS, Nagabhushan TL, and Turner WN

The Journal of antibiotics 29(5):488-91, 1976 May - Who cited this? | PubMed ID: 956035 | Fulltext

The gentamicin antibiotics. 7. Structures of the gentamicin antibiotics A1, A3, and A4.

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Nagabhushan TL, Turner WN, Daniels PJ, and Morton JB

The Journal of organic chemistry 40(19):2830-4, 1975 Sep 19 - Who cited this? | PubMed ID: 1177067 | Fulltext

The gentamicin antibiotics. 8. Structure of gentamicin A2.

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Nagabhushan TL, Daniels PJ, Jaret RS, and Morton JB

The Journal of organic chemistry 40(19):2835-6, 1975 Sep 19 - Who cited this? | PubMed ID: 1177068 | Fulltext

The gentamicin antibiotics. 6. Gentamicin C2b, an aminoglycoside antibiotic produced by Micromonospora purpurea mutant JI-33.

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Daniels PJ, Luce C, and Nagabhushan TL

The Journal of antibiotics 28(1):35-41, 1975 Jan - Who cited this? | PubMed ID: 1092638 | Fulltext

The synthesis of 1-N-[(S)-4-amino-2-hydroxybutyryl]gentamicin C1 and 1-N-[ (S) -3-amino-2-hydroxypropionyl]gentamicin C1.

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Daniels PJ, Weinstein J, and Nagabhushan TL

The Journal of antibiotics 27(11):889-93, 1974 Nov - Who cited this? | PubMed ID: 4217792 | Fulltext

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