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Papers authored by Muoio DM

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Metabolomics applied to diabetes research: moving from information to knowledge.

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Bain JR, Stevens RD, Wenner BR, Ilkayeva O, Muoio DM, and Newgard CB

Diabetes 58(11):2429-43, 2009 Nov - Who cited this? | PubMed ID: 19875619 | Fulltext

Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition.

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Li LO, Ellis JM, Paich HA, Wang S, Gong N, Altshuller G, Thresher RJ, Koves TR, Watkins SM, Muoio DM, Cline GW, Shulman GI, and Coleman RA

The Journal of biological chemistry 284(41):27816-26, 2009 Oct 9 - Who cited this? | PubMed ID: 19648649 | Fulltext

Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control.

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Noland RC, Koves TR, Seiler SE, Lum H, Lust RM, Ilkayeva O, Stevens RD, Hegardt FG, and Muoio DM

The Journal of biological chemistry 284(34):22840-52, 2009 Aug 21 - Who cited this? | PubMed ID: 19553674 | Fulltext

Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase.

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Ussher JR, Koves TR, Jaswal JS, Zhang L, Ilkayeva O, Dyck JR, Muoio DM, and Lopaschuk GD

Diabetes 58(8):1766-75, 2009 Aug - Who cited this? | PubMed ID: 19478144 | Fulltext

Increased Insulin Sensitivity in Mice Lacking Collectrin, a Downstream Target of HNF-1{alpha}.

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Malakauskas SM, Kourany WM, Zhang XY, Lu D, Stevens RD, Koves TR, Hohmeier HE, Muoio DM, Newgard CB, and Le TH

Molecular endocrinology (Baltimore, Md.) 23(6):881-92, 2009 Jun - Who cited this? | PubMed ID: 19246514 | Fulltext

Increased Insulin Sensitivity in Mice Lacking Collectrin, a Downstream Target of HNF-1{alpha}.

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Malakauskas SM, Kourany WM, Zhang XY, Lu D, Stevens RD, Koves TR, Hohmeier HE, Muoio DM, Newgard CB, and Le TH

Endocrine reviews 30(3):291, 2009 May - Who cited this? | PubMed ID: 19433647 | Fulltext

The STEDMAN Project: Biophysical, Biochemical and Metabolic Effects of a Behavioral Weight Loss Intervention during Weight Loss, Maintenance, and Regain.

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Lien LF, Haqq AM, Arlotto M, Slentz CA, Muehlbauer MJ, McMahon RL, Rochon J, Gallup D, Bain JR, Ilkayeva O, Wenner BR, Stevens RD, Millington DS, Muoio DM, Butler MD, Newgard CB,

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Omics : a journal of integrative biology 13(1):21-35, 2009 Feb - Who cited this? | PubMed ID: 19290809 | Fulltext

Metabolic profiling of PPAR{alpha}-/- mice reveals defects in carnitine and amino acid homeostasis that are partially reversed by oral carnitine supplementation.

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Makowski L, Noland RC, Koves TR, Xing W, Ilkayeva OR, Muehlbauer MJ, Stevens RD, and Muoio DM

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008 Oct 22 - Who cited this? | PubMed ID: 18945875 | Fulltext

Fatty acid oxidation and insulin action: when less is more.

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Muoio DM and Newgard CB

Diabetes 57(6):1455-6, 2008 Jun - Who cited this? | PubMed ID: 18511446 | Fulltext

Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression.

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Stoltzman CA, Peterson CW, Breen KT, Muoio DM, Billin AN, and Ayer DE

Proceedings of the National Academy of Sciences of the United States of America 105(19):6912, 2008 May 13 - Who cited this? | PubMed ID: 18458340 | Fulltext

Mechanisms of disease: molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes.

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Muoio DM and Newgard CB

Nature reviews. Molecular cell biology 9(3):193, 2008 Mar - Who cited this? | PubMed ID: 18200017 | Fulltext

Mitochondrial overload and incomplete Fatty Acid oxidation contribute to skeletal muscle insulin resistance.

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Koves TR, Ussher JR, Noland RC, Slentz D, Mosedale M, Ilkayeva O, Bain J, Stevens R, Dyck JR, Newgard CB, Lopaschuk GD, and Muoio DM

Cell metabolism 7(1):45-56, 2008 Jan - Who cited this? | PubMed ID: 18177724 | Fulltext

Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1alpha: implications for metabolic disease.

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Muoio DM and Koves TR

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 32(5):874-83, 2007 Oct - Who cited this? | PubMed ID: 18059612 | Fulltext

TXNIP links redox circuitry to glucose control.

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Muoio DM

Cell metabolism 5(6):412, 2007 Jun - Who cited this? | PubMed ID: 17550776 | Fulltext

Carnitine revisited: potential use as adjunctive treatment in diabetes.

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Power RA, Hulver MW, Zhang JY, Dubois J, Marchand RM, Ilkayeva O, Muoio DM, and Mynatt RL

Diabetologia 50(4):824-32, 2007 Apr - Who cited this? | PubMed ID: 17310372 | Fulltext

Contraction of insulin-resistant muscle normalizes insulin action in association with increased mitochondrial activity and fatty acid catabolism.

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Thyfault JP, Cree MG, Zheng D, Zwetsloot JJ, Tapscott EB, Koves TR, Ilkayeva O, Wolfe RR, Muoio DM, and Dohm GL

American journal of physiology. Cell physiology 292(2):C729-39, 2007 Feb - Who cited this? | PubMed ID: 17050616 | Fulltext

Lipid-induced metabolic dysfunction in skeletal muscle.

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Muoio DM and Koves TR

Novartis Foundation symposium 286:24, 2007 - Who cited this? | PubMed ID: 18269172 | Fulltext

Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs.

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Gaillard S, Grasfeder LL, Haeffele CL, Lobenhofer EK, Chu TM, Wolfinger R, Kazmin D, Koves TR, Muoio DM, Chang CY, and McDonnell DP

Molecular cell 24(5):797-803, 2006 Dec 8 - Who cited this? | PubMed ID: 17157261 | Fulltext

Obesity-related derangements in metabolic regulation.

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Muoio DM and Newgard CB

Annual review of biochemistry 75:367-401, 2006 - Who cited this? | PubMed ID: 16756496 | Fulltext

Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans.

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Hulver MW, Berggren JR, Carper MJ, Miyazaki M, Ntambi JM, Hoffman EP, Thyfault JP, Stevens R, Dohm GL, Houmard JA, and Muoio DM

Cell metabolism 2(4):251, 2005 Oct - Who cited this? | PubMed ID: 16213227 | Fulltext

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

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Koves TR, Li P, An J, Akimoto T, Slentz D, Ilkayeva O, Dohm GL, Yan Z, Newgard CB, and Muoio DM

The Journal of biological chemistry 280(39):33588-98, 2005 Sep 30 - Who cited this? | PubMed ID: 16079133 | Fulltext

Metabolism: A is for adipokine.

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Muoio DM and Newgard CB

Nature 436(7049):337-8, 2005 Jul 21 - Who cited this? | PubMed ID: 16034406 | Fulltext

Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs.

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Hammond LE, Neschen S, Romanelli AJ, Cline GW, Ilkayeva OR, Shulman GI, Muoio DM, and Coleman RA

The Journal of biological chemistry 280(27):25629-36, 2005 Jul 8 - Who cited this? | PubMed ID: 15878874 | Fulltext

Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism.

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Koves TR, Noland RC, Bates AL, Henes ST, Muoio DM, and Cortright RN

American journal of physiology. Cell physiology 288(5):C1074-82, 2005 May - Who cited this? | PubMed ID: 15647392 | Fulltext

Glucose uptake in muscle cell cultures from endurance-trained men.

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Berggren JR, Tanner CJ, Koves TR, Muoio DM, and Houmard JA

Medicine and science in sports and exercise 37(4):579-84, 2005 Apr - Who cited this? | PubMed ID: 15809555 | Fulltext

Biomedicine. Insulin resistance takes a trip through the ER.

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Muoio DM and Newgard CB

Science (New York, N.Y.) 306(5695):425-6, 2004 Oct 15 - Who cited this? | PubMed ID: 15486283 | Fulltext

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance.

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An J, Muoio DM, Shiota M, Fujimoto Y, Cline GW, Shulman GI, Koves TR, Stevens R, Millington D, and Newgard CB

Nature medicine 10(3):268-74, 2004 Mar - Who cited this? | PubMed ID: 14770177 | Fulltext

Peripheral metabolic actions of leptin.

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Muoio DM and Lynis Dohm G

Best practice & research. Clinical endocrinology & metabolism 16(4):653-66, 2002 Dec - Who cited this? | PubMed ID: 12468413 | Fulltext

Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta.

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Muoio DM, MacLean PS, Lang DB, Li S, Houmard JA, Way JM, Winegar DA, Corton JC, Dohm GL, and Kraus WE

The Journal of biological chemistry 277(29):26089-97, 2002 Jul 19 - Who cited this? | PubMed ID: 12118038 | Fulltext

Evidence of a malonyl-CoA-insensitive carnitine palmitoyltransferase I activity in red skeletal muscle.

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Kim JY, Koves TR, Yu GS, Gulick T, Cortright RN, Dohm GL, and Muoio DM

American journal of physiology. Endocrinology and metabolism 282(5):E1014-22, 2002 May - Who cited this? | PubMed ID: 11934665 | Fulltext

Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells.

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Muoio DM, Way JM, Tanner CJ, Winegar DA, Kliewer SA, Houmard JA, Kraus WE, and Dohm GL

Diabetes 51(4):901-9, 2002 Apr - Who cited this? | PubMed ID: 11916905 | Fulltext

Acyl-CoAs are functionally channeled in liver: potential role of acyl-CoA synthetase.

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Muoio DM, Lewin TM, Wiedmer P, and Coleman RA

American journal of physiology. Endocrinology and metabolism 279(6):E1366-73, 2000 Dec - Who cited this? | PubMed ID: 11093925 | Fulltext

Energy metabolism in uncoupling protein 3 gene knockout mice.

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Vidal-Puig AJ, Grujic D, Zhang CY, Hagen T, Boss O, Ido Y, Szczepanik A, Wade J, Mootha V, Cortright R, Muoio DM, and Lowell BB

The Journal of biological chemistry 275(21):16258-66, 2000 May 26 - Who cited this? | PubMed ID: 10748196 | Fulltext

Physiological and nutritional regulation of enzymes of triacylglycerol synthesis.

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Coleman RA, Lewin TM, and Muoio DM

Annual review of nutrition 20:77-103, 2000 - Who cited this? | PubMed ID: 10940327 | Fulltext

Leptin opposes insulin's effects on fatty acid partitioning in muscles isolated from obese ob/ob mice.

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Muoio DM, Dohm GL, Tapscott EB, and Coleman RA

The American journal of physiology 276(5 Pt 1):E913-21, 1999 May - Who cited this? | PubMed ID: 10329986 | Fulltext

AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target.

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Muoio DM, Seefeld K, Witters LA, and Coleman RA

The Biochemical journal 338 ( Pt 3):783-91, 1999 Mar 15 - Who cited this? | PubMed ID: 10051453 | Fulltext

Leptin directly alters lipid partitioning in skeletal muscle.

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Muoio DM, Dohm GL, Fiedorek FT, Tapscott EB, and Coleman RA

Diabetes 46(8):1360-3, 1997 Aug - Who cited this? | PubMed ID: 9231663 | Fulltext

Effect of dietary fat on metabolic adjustments to maximal VO2 and endurance in runners.

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Muoio DM, Leddy JJ, Horvath PJ, Awad AB, and Pendergast DR

Medicine and science in sports and exercise 26(1):81-8, 1994 Jan - Who cited this? | PubMed ID: 8133743 | Fulltext

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