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Papers authored by Motley ED

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Distinct roles of protease-activated receptors in signal transduction regulation of endothelial nitric oxide synthase.

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Suzuki H, Motley ED, Eguchi K, Hinoki A, Shirai H, Watts V, Stemmle LN, Fields TA, and Eguchi S

Hypertension 53(2):182-8, 2009 Feb - Who cited this? | PubMed ID: 19064814 | Fulltext

Role of protease-activated receptor-1 in endothelial nitric oxide synthase-thr495 phosphorylation.

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Watts VL and Motley ED

Experimental biology and medicine (Maywood, N.J.) 234(2):132-9, 2009 Feb - Who cited this? | PubMed ID: 19064940 | Fulltext

Mechanism of endothelial nitric oxide synthase phosphorylation and activation by thrombin.

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Motley ED, Eguchi K, Patterson MM, Palmer PD, Suzuki H, and Eguchi S

Hypertension 49(3):577-83, 2007 Mar - Who cited this? | PubMed ID: 17210830 | Fulltext

Activation of endothelial nitric oxide synthase by the angiotensin II type 1 receptor.

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Suzuki H, Eguchi K, Ohtsu H, Higuchi S, Dhobale S, Frank GD, Motley ED, and Eguchi S

Endocrinology 147(12):5914-20, 2006 Dec - Who cited this? | PubMed ID: 16980435 | Fulltext

Angiotensin II signal transduction through small GTP-binding proteins: mechanism and significance in vascular smooth muscle cells.

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Ohtsu H, Suzuki H, Nakashima H, Dhobale S, Frank GD, Motley ED, and Eguchi S

Hypertension 48(4):534-40, 2006 Oct - Who cited this? | PubMed ID: 16923993 | Fulltext

Angiotensin II-induced activation of p21-activated kinase 1 requires Ca2+ and protein kinase C{delta} in vascular smooth muscle cells.

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Woolfolk EA, Eguchi S, Ohtsu H, Nakashima H, Ueno H, Gerthoffer WT, and Motley ED

American journal of physiology. Cell physiology 289(5):C1286-94, 2005 Nov - Who cited this? | PubMed ID: 16033904 | Fulltext

Recent progress in signal transduction research of the angiotensin II type-1 receptor: protein kinases, vascular dysfunction and structural requirement.

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Suzuki H, Motley ED, Frank GD, Utsunomiya H, and Eguchi S

Current medicinal chemistry. Cardiovascular and hematological agents 3(4):305-22, 2005 Oct - Who cited this? | PubMed ID: 16250862 | Fulltext

Signal-crosstalk between Rho/ROCK and c-Jun NH2-terminal kinase mediates migration of vascular smooth muscle cells stimulated by angiotensin II.

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Ohtsu H, Mifune M, Frank GD, Saito S, Inagami T, Kim-Mitsuyama S, Takuwa Y, Sasaki T, Rothstein JD, Suzuki H, Nakashima H, Woolfolk EA, Motley ED, and Eguchi S

Arteriosclerosis, thrombosis, and vascular biology 25(9):1831-6, 2005 Sep - Who cited this? | PubMed ID: 15994438 | Fulltext

The role of reactive oxygen species in insulin signaling in the vasculature.

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Frank GD, Eguchi S, and Motley ED

Antioxidants & redox signaling 7(7-8):1053-61, 2005 - Who cited this? | PubMed ID: 15998260 | Fulltext

Overexpression of Cu/Zn-superoxide dismutase and/or catalase in mice inhibits aorta smooth muscle cell proliferation.

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Shi M, Yang H, Motley ED, and Guo Z

American journal of hypertension : journal of the American Society of Hypertension 17(5 Pt 1):450-6, 2004 May - Who cited this? | PubMed ID: 15110906 | Fulltext

3-Morpholinosyndnonimine inhibits 5-hydroxytryptamine-induced phosphorylation of nitric oxide synthase in endothelial cells.

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Richardson SM, Maleque MA, and Motley ED

Cellular and molecular biology (Noisy-le-Grand, France) 49(8):1385-9, 2003 Dec - Who cited this? | PubMed ID: 14984014 | Fulltext

Hydrogen peroxide inhibits insulin signaling in vascular smooth muscle cells.

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Gardner CD, Eguchi S, Reynolds CM, Eguchi K, Frank GD, and Motley ED

Experimental biology and medicine (Maywood, N.J.) 228(7):836-42, 2003 Jul - Who cited this? | PubMed ID: 12876303 | Fulltext

Insulin-induced Akt activation is inhibited by angiotensin II in the vasculature through protein kinase C-alpha.

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Motley ED, Eguchi K, Gardner C, Hicks AL, Reynolds CM, Frank GD, Mifune M, Ohba M, and Eguchi S

Hypertension 41(3 Pt 2):775-80, 2003 Mar - Who cited this? | PubMed ID: 12623995 | Fulltext

Fruit-juice concentrate of Asian plum inhibits growth signals of vascular smooth muscle cells induced by angiotensin II.

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Utsunomiya H, Takekoshi S, Gato N, Utatsu H, Motley ED, Eguchi K, Fitzgerald TG, Mifune M, Frank GD, and Eguchi S

Life sciences 72(6):659-67, 2002 Dec 27 - Who cited this? | PubMed ID: 12467906 | Fulltext

Ligand-independent trans-activation of the platelet-derived growth factor receptor by reactive oxygen species requires protein kinase C-delta and c-Src.

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Saito S, Frank GD, Mifune M, Ohba M, Utsunomiya H, Motley ED, Inagami T, and Eguchi S

The Journal of biological chemistry 277(47):44695-700, 2002 Nov 22 - Who cited this? | PubMed ID: 12226102 | Fulltext

Metalloprotease inhibitor blocks angiotensin II-induced migration through inhibition of epidermal growth factor receptor transactivation.

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Saito S, Frank GD, Motley ED, Dempsey PJ, Utsunomiya H, Inagami T, and Eguchi S

Biochemical and biophysical research communications 294(5):1023-9, 2002 Jun 28 - Who cited this? | PubMed ID: 12074579 | Fulltext

Cyclosporin A inhibits angiotensin II-induced c-Jun NH(2)-terminal kinase activation but not protein synthesis in vascular smooth muscle cells.

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Saito S, Frank GD, Motley ED, Utsunomiya H, Inagami T, and Eguchi S

European journal of pharmacology 443(1-3):47-50, 2002 May 17 - Who cited this? | PubMed ID: 12044791 | Fulltext

Lysophosphatidylcholine activates extracellular signal-regulated kinases 1/2 through reactive oxygen species in rat vascular smooth muscle cells.

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Yamakawa T, Tanaka S, Yamakawa Y, Kamei J, Numaguchi K, Motley ED, Inagami T, and Eguchi S

Arteriosclerosis, thrombosis, and vascular biology 22(5):752-8, 2002 May 1 - Who cited this? | PubMed ID: 12006386 | Fulltext

Requirement of Ca(2+) and PKCdelta for Janus kinase 2 activation by angiotensin II: involvement of PYK2.

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Frank GD, Saito S, Motley ED, Sasaki T, Ohba M, Kuroki T, Inagami T, and Eguchi S

Molecular endocrinology (Baltimore, Md.) 16(2):367-77, 2002 Feb - Who cited this? | PubMed ID: 11818507 | Fulltext

Lysophosphatidylcholine inhibits insulin-induced Akt activation through protein kinase C-alpha in vascular smooth muscle cells.

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Motley ED, Kabir SM, Gardner CD, Eguchi K, Frank GD, Kuroki T, Ohba M, Yamakawa T, and Eguchi S

Hypertension 39(2 Pt 2):508-12, 2002 Feb - Who cited this? | PubMed ID: 11882599 | Fulltext

Signaling mechanisms of heparin-binding epidermal growth factor-like growth factor in vascular smooth muscle cells.

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Reynolds CM, Eguchi S, Frank GD, and Motley ED

Hypertension 39(2 Pt 2):525-9, 2002 Feb - Who cited this? | PubMed ID: 11882602 | Fulltext

Protein kinase C inhibits insulin-induced Akt activation in vascular smooth muscle cells.

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Motley ED, Kabir SM, Eguchi K, Hicks AL, Gardner CD, Reynolds CM, Frank GD, and Eguchi S

Cellular and molecular biology (Noisy-le-Grand, France) 47(6):1059-62, 2001 Sep - Who cited this? | PubMed ID: 11785657 | Fulltext

Unique regulation of c-Jun N-terminal kinase by PYK2/CAK-beta in angiotensin II-stimulated vascular smooth muscle cells.

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Frank GD, Eguchi S, Motley ED, Sasaki T, and Inagami T

Biochemical and biophysical research communications 286(4):692-6, 2001 Aug 31 - Who cited this? | PubMed ID: 11520052 | Fulltext

Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK.

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Eguchi S, Dempsey PJ, Frank GD, Motley ED, and Inagami T

The Journal of biological chemistry 276(11):7957-62, 2001 Mar 16 - Who cited this? | PubMed ID: 11116149 | Fulltext

N-acetylcysteine inhibits angiotensin ii-mediated activation of extracellular signal-regulated kinase and epidermal growth factor receptor.

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Frank GD, Eguchi S, Inagami T, and Motley ED

Biochemical and biophysical research communications 280(4):1116-9, 2001 Feb 2 - Who cited this? | PubMed ID: 11162642 | Fulltext

Involvement of reactive oxygen species in the activation of tyrosine kinase and extracellular signal-regulated kinase by angiotensin II.

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Frank GD, Eguchi S, Yamakawa T, Tanaka S, Inagami T, and Motley ED

Endocrinology 141(9):3120-6, 2000 Sep - Who cited this? | PubMed ID: 10965882 | Fulltext

PYK2/CAKbeta represents a redox-sensitive tyrosine kinase in vascular smooth muscle cells.

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Frank GD, Motley ED, Inagami T, and Eguchi S

Biochemical and biophysical research communications 270(3):761-5, 2000 Apr 21 - Who cited this? | PubMed ID: 10772898 | Fulltext

5-hydroxytryptamine stimulates phosphorylation of p44/p42 mitogen-activated protein kinase activation in bovine aortic endothelial cell cultures.

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McDuffie JE, Motley ED, Limbird LE, and Maleque MA

Journal of cardiovascular pharmacology 35(3):398-402, 2000 Mar - Who cited this? | PubMed ID: 10710124 | Fulltext

Involvement of Rho-kinase in angiotensin II-induced hypertrophy of rat vascular smooth muscle cells.

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Yamakawa T, Tanaka S, Numaguchi K, Yamakawa Y, Motley ED, Ichihara S, and Inagami T

Hypertension 35(1 Pt 2):313-8, 2000 Jan - Who cited this? | PubMed ID: 10642317 | Fulltext

Intracellular signaling of angiotensin II-induced p70 S6 kinase phosphorylation at Ser(411) in vascular smooth muscle cells. Possible requirement of epidermal growth factor receptor, Ras, extracellular signal-regulated kinase, and Akt.

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Eguchi S, Iwasaki H, Ueno H, Frank GD, Motley ED, Eguchi K, Marumo F, Hirata Y, and Inagami T

The Journal of biological chemistry 274(52):36843-51, 1999 Dec 24 - Who cited this? | PubMed ID: 10601235 | Fulltext

Intracellular signaling in rat cultured vascular smooth muscle cells: roles of nuclear factor-kappaB and p38 mitogen-activated protein kinase on tumor necrosis factor-alpha production.

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Yamakawa T, Eguchi S, Matsumoto T, Yamakawa Y, Numaguchi K, Miyata I, Reynolds CM, Motley ED, and Inagami T

Endocrinology 140(8):3562, 1999 Aug - Who cited this? | PubMed ID: 10433212 | Fulltext

Mechanotransduction of rat aortic vascular smooth muscle cells requires RhoA and intact actin filaments.

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Numaguchi K, Eguchi S, Yamakawa T, Motley ED, and Inagami T

Circulation research 85(1):5-11, 1999 Jul 9 - Who cited this? | PubMed ID: 10400905 | Fulltext

Epidermal growth factor receptor is indispensable for c-Fos expression and protein synthesis by angiotensin II.

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Eguchi S, Iwasaki H, Hirata Y, Frank GD, Motley ED, Yamakawa T, Numaguchi K, and Inagami T

European journal of pharmacology 376(1-2):203-6, 1999 Jul 2 - Who cited this? | PubMed ID: 10440105 | Fulltext

Cross-talk between angiotensin II receptors and the tyrosine kinases and phosphatases.

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Inagami T, Eguchi S, Numaguchi K, Motley ED, Tang H, Matsumoto T, and Yamakawa T

Journal of the American Society of Nephrology : JASN 10 Suppl 11:S57-61, 1999 Jan - Who cited this? | PubMed ID: 9892141 | Fulltext

Involvement of PYK2 in angiotensin II signaling of vascular smooth muscle cells.

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Eguchi S, Iwasaki H, Inagami T, Numaguchi K, Yamakawa T, Motley ED, Owada KM, Marumo F, and Hirata Y

Hypertension 33(1 Pt 2):201-6, 1999 Jan - Who cited this? | PubMed ID: 9931105 | Fulltext

Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells.

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Eguchi S, Numaguchi K, Iwasaki H, Matsumoto T, Yamakawa T, Utsunomiya H, Motley ED, Kawakatsu H, Owada KM, Hirata Y, Marumo F, and Inagami T

The Journal of biological chemistry 273(15):8890-6, 1998 Apr 10 - Who cited this? | PubMed ID: 9535870 | Fulltext

Lysophosphatidylcholine stimulates MAP kinase activity in rat vascular smooth muscle cells.

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Yamakawa T, Eguchi S, Yamakawa Y, Motley ED, Numaguchi K, Utsunomiya H, and Inagami T

Hypertension 31(1 Pt 2):248-53, 1998 Jan - Who cited this? | PubMed ID: 9453311 | Fulltext

Neurobiological actions of cocaine in the hippocampus.

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Onaivi ES, Bishop-Robinson C, Motley ED, Chakrabarti A, and Chirwa SS

Annals of the New York Academy of Sciences 801:76-94, 1996 Oct 31 - Who cited this? | PubMed ID: 8959025 | Fulltext

Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. Possible requirement of Gq-mediated p21ras activation coupled to a Ca2+/calmodulin-sensitive tyrosine kinase.

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Eguchi S, Matsumoto T, Motley ED, Utsunomiya H, and Inagami T

The Journal of biological chemistry 271(24):14169-75, 1996 Jun 14 - Who cited this? | PubMed ID: 8662912 | Fulltext

Role of Na(+)-Ca2+ exchange in the regulation of vascular smooth muscle tension.

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Motley ED, Paul RJ, and Matlib MA

The American journal of physiology 264(4 Pt 2):H1028-40, 1993 Apr - Who cited this? | PubMed ID: 8386477 | Fulltext

The effect of pertussis toxin treatment on alpha-1-adrenoceptor-mediated pressor responses in the pithed rat: dependence on agonist efficacy but not chemical class.

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Motley ED, Ruffolo RR, and Nichols AJ

Pharmacology 45(6):338-44, 1992 - Who cited this? | PubMed ID: 1362614 | Fulltext

The effect of pertussis toxin on alpha 1-adrenoceptor-mediated vasoconstriction by the full agonist, cirazoline, and the partial agonist, (-)-dobutamine, in pithed rats.

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Ruffolo RR, Motley ED, and Nichols AJ

Fundamental & clinical pharmacology 5(1):11-23, 1991 - Who cited this? | PubMed ID: 1676694 | Fulltext

Role of phosphatidylinositol turnover in the contraction of the rat aorta.

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Motley ED, Ruffolo RR, Hay DW, and Nichols AJ

Advances in experimental medicine and biology 308:211-6, 1991 - Who cited this? | PubMed ID: 1801584 | Fulltext

Effect of pertussis toxin treatment on postjunctional alpha-1 and alpha-2 adrenoceptor function in the cardiovascular system of the pithed rat.

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Nichols AJ, Motley ED, and Ruffolo RR

The Journal of pharmacology and experimental therapeutics 249(1):203-9, 1989 Apr - Who cited this? | PubMed ID: 2468761 | Fulltext

Differential effect of pertussis toxin on pre- and postjunctional alpha 2-adrenoceptors in the cardiovascular system of the pithed rat.

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Nichols AJ, Motley ED, and Ruffolo RR

European journal of pharmacology 145(3):345-9, 1988 Jan 19 - Who cited this? | PubMed ID: 2895005 | Fulltext

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