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Papers authored by Minokoshi Y

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Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues.

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Xue B, Pulinilkunnil T, Murano I, Bence KK, He H, Minokoshi Y, Asakura K, Lee A, Haj F, Furukawa N, Catalano KJ, Delibegovic M, Balschi JA, Cinti S, Neel BG, and Kahn BB

Molecular and cellular biology 29(16):4563-73, 2009 Aug - Who cited this? | PubMed ID: 19528236 | Fulltext

Regulation of pancreatic beta cell mass by neuronal signals from the liver.

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Imai J, Katagiri H, Yamada T, Ishigaki Y, Suzuki T, Kudo H, Uno K, Hasegawa Y, Gao J, Kaneko K, Ishihara H, Niijima A, Nakazato M, Asano T, Minokoshi Y, and Oka Y

Science (New York, N.Y.) 322(5905):1250-4, 2008 Nov 21 - Who cited this? | PubMed ID: 19023081 | Fulltext

Role of hypothalamic AMP-kinase in food intake regulation.

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Minokoshi Y, Shiuchi T, Lee S, Suzuki A, and Okamoto S

Nutrition (Burbank, Los Angeles County, Calif.) 24(9):786-90, 2008 Sep - Who cited this? | PubMed ID: 18725075 | Fulltext

Ghrelin raises [Ca(2+)](i) via AMPK in hypothalamic arcuate nucleus NPY neurons.

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Kohno D, Sone H, Minokoshi Y, and Yada T

Biochemical and biophysical research communications 366(2):388-92, 2008 Feb 8 - Who cited this? | PubMed ID: 18068666 | Fulltext

Ceramide and adenosine 5'-monophosphate-activated protein kinase are two novel regulators of 11beta-hydroxysteroid dehydrogenase type 1 expression and activity in cultured preadipocytes.

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Arai N, Masuzaki H, Tanaka T, Ishii T, Yasue S, Kobayashi N, Tomita T, Noguchi M, Kusakabe T, Fujikura J, Ebihara K, Hirata M, Hosoda K, Hayashi T, Sawai H, Minokoshi Y,

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Endocrinology 148(11):5268-77, 2007 Nov - Who cited this? | PubMed ID: 17702848 | Fulltext

Disruption of CXC motif chemokine ligand-14 in mice ameliorates obesity-induced insulin resistance.

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Nara N, Nakayama Y, Okamoto S, Tamura H, Kiyono M, Muraoka M, Tanaka K, Taya C, Shitara H, Ishii R, Yonekawa H, Minokoshi Y, and Hara T

The Journal of biological chemistry 282(42):30794, 2007 Oct 19 - Who cited this? | PubMed ID: 17724031 | Fulltext

Dmbx1 is essential in agouti-related protein action.

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Fujimoto W, Shiuchi T, Miki T, Minokoshi Y, Takahashi Y, Takeuchi A, Kimura K, Saito M, Iwanaga T, and Seino S

Proceedings of the National Academy of Sciences of the United States of America 104(39):15514-9, 2007 Sep 25 - Who cited this? | PubMed ID: 17873059 | Fulltext

An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation.

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Miura S, Kawanaka K, Kai Y, Tamura M, Goto M, Shiuchi T, Minokoshi Y, and Ezaki O

Endocrinology 148(7):3441, 2007 Jul - Who cited this? | PubMed ID: 17446185 | Fulltext

Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.

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Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T,

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Cell metabolism 6(1):55-68, 2007 Jul - Who cited this? | PubMed ID: 17618856 | Fulltext

Leptin stimulates fatty acid oxidation and peroxisome proliferator-activated receptor alpha gene expression in mouse C2C12 myoblasts by changing the subcellular localization of the alpha2 form of AMP-activated protein kinase.

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Suzuki A, Okamoto S, Lee S, Saito K, Shiuchi T, and Minokoshi Y

Molecular and cellular biology 27(12):4317-27, 2007 Jun - Who cited this? | PubMed ID: 17420279 | Fulltext

Central melanocortin signaling restores skeletal muscle AMP-activated protein kinase phosphorylation in mice fed a high-fat diet.

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Tanaka T, Masuzaki H, Yasue S, Ebihara K, Shiuchi T, Ishii T, Arai N, Hirata M, Yamamoto H, Hayashi T, Hosoda K, Minokoshi Y, and Nakao K

Cell metabolism 5(5):395-402, 2007 May - Who cited this? | PubMed ID: 17488641 | Fulltext

Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism.

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Kim YB, Peroni OD, Aschenbach WG, Minokoshi Y, Kotani K, Zisman A, Kahn CR, Goodyear LJ, and Kahn BB

Molecular and cellular biology 25(21):9713-23, 2005 Nov - Who cited this? | PubMed ID: 16227617 | Fulltext

Ventromedial hypothalamic nucleus-specific enhancer of Ad4BP/SF-1 gene.

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Shima Y, Zubair M, Ishihara S, Shinohara Y, Oka S, Kimura S, Okamoto S, Minokoshi Y, Suita S, and Morohashi K

Molecular endocrinology (Baltimore, Md.) 19(11):2812-23, 2005 Nov - Who cited this? | PubMed ID: 15994202 | Fulltext

Skeletal muscle AMP-activated protein kinase phosphorylation parallels metabolic phenotype in leptin transgenic mice under dietary modification.

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Tanaka T, Hidaka S, Masuzaki H, Yasue S, Minokoshi Y, Ebihara K, Chusho H, Ogawa Y, Toyoda T, Sato K, Miyanaga F, Fujimoto M, Tomita T, Kusakabe T, Kobayashi N, Tanioka H,

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Diabetes 54(8):2365-74, 2005 Aug - Who cited this? | PubMed ID: 16046303 | Fulltext

Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes.

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Maeda K, Cao H, Kono K, Gorgun CZ, Furuhashi M, Uysal KT, Cao Q, Atsumi G, Malone H, Krishnan B, Minokoshi Y, Kahn BB, Parker RA, and Hotamisligil GS

Cell metabolism 1(2):107, 2005 Feb - Who cited this? | PubMed ID: 16054052 | Fulltext

GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization.

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Kotani K, Peroni OD, Minokoshi Y, Boss O, and Kahn BB

The Journal of clinical investigation 114(11):1666-75, 2004 Dec - Who cited this? | PubMed ID: 15578099 | Fulltext

Leptin signaling targets the thyrotropin-releasing hormone gene promoter in vivo.

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Guo F, Bakal K, Minokoshi Y, and Hollenberg AN

Endocrinology 145(5):2221-7, 2004 May - Who cited this? | PubMed ID: 14764630 | Fulltext

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus.

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Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, Mu J, Foufelle F, Ferré P, Birnbaum MJ, Stuck BJ, and Kahn BB

Nature 428(6982):569-74, 2004 Apr 1 - Who cited this? | PubMed ID: 15058305 | Fulltext

Tissue-specific ablation of the GLUT4 glucose transporter or the insulin receptor challenges assumptions about insulin action and glucose homeostasis.

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Minokoshi Y, Kahn CR, and Kahn BB

The Journal of biological chemistry 278(36):33609-12, 2003 Sep 5 - Who cited this? | PubMed ID: 12788932 | Fulltext

Role of AMP-activated protein kinase in leptin-induced fatty acid oxidation in muscle.

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Minokoshi Y and Kahn BB

Biochemical Society transactions 31(Pt 1):196-201, 2003 Feb - Who cited this? | PubMed ID: 12546684 | Fulltext

ATP-sensitive potassium channels participate in glucose uptake in skeletal muscle and adipose tissue.

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Miki T, Minami K, Zhang L, Morita M, Gonoi T, Shiuchi T, Minokoshi Y, Renaud JM, and Seino S

American journal of physiology. Endocrinology and metabolism 283(6):E1178-84, 2002 Dec - Who cited this? | PubMed ID: 12388128 | Fulltext

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase.

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Yamauchi T, Kamon J, Minokoshi Y, Ito Y, Waki H, Uchida S, Yamashita S, Noda M, Kita S, Ueki K, Eto K, Akanuma Y, Froguel P, Foufelle F, Ferre P, Carling D,

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Nature medicine 8(11):1288-95, 2002 Nov - Who cited this? | PubMed ID: 12368907 | Fulltext

PTP1B regulates leptin signal transduction in vivo.

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Zabolotny JM, Bence-Hanulec KK, Stricker-Krongrad A, Haj F, Wang Y, Minokoshi Y, Kim YB, Elmquist JK, Tartaglia LA, Kahn BB, and Neel BG

Developmental cell 2(4):489-95, 2002 Apr - Who cited this? | PubMed ID: 11970898 | Fulltext

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase.

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Minokoshi Y, Kim YB, Peroni OD, Fryer LG, Müller C, Carling D, and Kahn BB

Nature 415(6869):339-43, 2002 Jan 17 - Who cited this? | PubMed ID: 11797013 | Fulltext

ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.

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Miki T, Liss B, Minami K, Shiuchi T, Saraya A, Kashima Y, Horiuchi M, Ashcroft F, Minokoshi Y, Roeper J, and Seino S

Nature neuroscience 4(5):507-12, 2001 May - Who cited this? | PubMed ID: 11319559 | Fulltext

Involvement of bradykinin and nitric oxide in leptin-mediated glucose uptake in skeletal muscle.

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Shiuchi T, Nakagami H, Iwai M, Takeda Y, Cui T, Chen R, Minokoshi Y, and Horiuchi M

Endocrinology 142(2):608-12, 2001 Feb - Who cited this? | PubMed ID: 11159831 | Fulltext

Aggravation of chemically-induced injury in perfused rat liver by extracellular ATP.

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Cui TX, Iwai M, Hamai M, Minokoshi Y, Shimazu T, and Horiuchi M

Life sciences 66(26):2593-601, 2000 May 19 - Who cited this? | PubMed ID: 10883737 | Fulltext

Interferon-gamma induces AT(2) receptor expression in fibroblasts by Jak/STAT pathway and interferon regulatory factor-1.

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Horiuchi M, Hayashida W, Akishita M, Yamada S, Lehtonen JY, Tamura K, Daviet L, Chen YE, Hamai M, Cui TX, Iwai M, and Minokoshi Y

Circulation research 86(2):233-40, 2000 Feb 4 - Who cited this? | PubMed ID: 10666420 | Fulltext

Role of the sympathetic nervous system and insulin in enhancing glucose uptake in peripheral tissues after intrahypothalamic injection of leptin in rats.

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Haque MS, Minokoshi Y, Hamai M, Iwai M, Horiuchi M, and Shimazu T

Diabetes 48(9):1706-12, 1999 Sep - Who cited this? | PubMed ID: 10480598 | Fulltext

L-Glutamate and insulin enhance glycogen synthesis in cultured astrocytes from the rat brain through different intracellular mechanisms.

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Hamai M, Minokoshi Y, and Shimazu T

Journal of neurochemistry 73(1):400-7, 1999 Jul - Who cited this? | PubMed ID: 10386993 | Fulltext

Cross talk between angiotensin II type 1 and type 2 receptors: cellular mechanism of angiotensin type 2 receptor-mediated cell growth inhibition.

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Xoriuchi M, Hamai M, Cui TX, Iwai M, and Minokoshi Y

Hypertension research : official journal of the Japanese Society of Hypertension 22(2):67-74, 1999 Jul - Who cited this? | PubMed ID: 10487321 | Fulltext

Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats.

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Minokoshi Y, Haque MS, and Shimazu T

Diabetes 48(2):287-91, 1999 Feb - Who cited this? | PubMed ID: 10334303 | Fulltext

Effects of noradrenaline on the cell-surface glucose transporters in cultured brown adipocytes: novel mechanism for selective activation of GLUT1 glucose transporters.

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Shimizu Y, Satoh S, Yano H, Minokoshi Y, Cushman SW, and Shimazu T

The Biochemical journal 330 ( Pt 1):397-403, 1998 Feb 15 - Who cited this? | PubMed ID: 9461536 | Fulltext

The beta3-adrenergic agonist BRL37344 increases glucose transport into L6 myocytes through a mechanism different from that of insulin.

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Tanishita T, Shimizu Y, Minokoshi Y, and Shimazu T

Journal of biochemistry 122(1):90-5, 1997 Jul - Who cited this? | PubMed ID: 9276675 | Fulltext

Activation of mitogen-activated protein kinase by norepinephrine in brown adipocytes from rats.

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Shimizu Y, Tanishita T, Minokoshi Y, and Shimazu T

Endocrinology 138(1):248-53, 1997 Jan - Who cited this? | PubMed ID: 8977410 | Fulltext

Noradrenaline increases glucose transport into brown adipocytes in culture by a mechanism different from that of insulin.

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Shimizu Y, Kielar D, Minokoshi Y, and Shimazu T

The Biochemical journal 314 ( Pt 2):485-90, 1996 Mar 1 - Who cited this? | PubMed ID: 8670061 | Fulltext

Expression of beta3-adrenoceptor and stimulation of glucose transport by beta3-agonists in brown adipocyte primary culture.

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Nikami H, Shimizu Y, Sumida M, Minokoshi Y, Yoshida T, Saito M, and Shimazu T

Journal of biochemistry 119(1):120-5, 1996 Jan - Who cited this? | PubMed ID: 8907185 | Fulltext

Regulatory mechanism of the ventromedial hypothalamus in enhancing glucose uptake in skeletal muscles.

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Minokoshi Y, Okano Y, and Shimazu T

Brain research 649(1-2):343-7, 1994 Jun 27 - Who cited this? | PubMed ID: 7953650 | Fulltext

Dexamethasone induces the GLUT4 glucose transporter, and responses of glucose transport to norepinephrine and insulin in primary cultures of brown adipocytes.

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Shimizu Y, Kielar D, Masuno H, Minokoshi Y, and Shimazu T

Journal of biochemistry 115(6):1069-74, 1994 Jun - Who cited this? | PubMed ID: 7982884 | Fulltext

Effect of a beta 3-adrenergic agonist, BRL35135A, on glucose uptake in rat skeletal muscle in vivo and in vitro.

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Abe H, Minokoshi Y, and Shimazu T

The Journal of endocrinology 139(3):479-86, 1993 Dec - Who cited this? | PubMed ID: 7907647 | Fulltext

Effects of ventromedial hypothalamic stimulation on glucose transport system in rat tissues.

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Takahashi A, Sudo M, Minokoshi Y, and Shimazu T

The American journal of physiology 263(6 Pt 2):R1228-34, 1992 Dec - Who cited this? | PubMed ID: 1481931 | Fulltext

Ventromedial hypothalamic stimulation enhances peripheral glucose uptake in anesthetized rats.

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Sudo M, Minokoshi Y, and Shimazu T

The American journal of physiology 261(3 Pt 1):E298-303, 1991 Sep - Who cited this? | PubMed ID: 1887876 | Fulltext

Role of the hypothalamus in insulin-independent glucose uptake in peripheral tissues.

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Shimazu T, Sudo M, Minokoshi Y, and Takahashi A

Brain research bulletin 27(3-4):501-4, 1991 - Who cited this? | PubMed ID: 1959052 | Fulltext

Adrenergic blockade paradoxically increases lipogenic response of brown adipose tissue to sympathetic nerve stimulation.

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Minokoshi Y, Saito M, and Shimazu T

Neuroscience letters 109(3):341-6, 1990 Feb 16 - Who cited this? | PubMed ID: 2158641 | Fulltext

Metabolic and sympathetic nerve activities of brown adipose tissue in tube-fed rats.

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Saito M, Minokoshi Y, and Shimazu T

The American journal of physiology 257(3 Pt 1):E374-8, 1989 Sep - Who cited this? | PubMed ID: 2506762 | Fulltext

Accelerated norepinephrine turnover in peripheral tissues after ventromedial hypothalamic stimulation in rats.

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Saito M, Minokoshi Y, and Shimazu T

Brain research 481(2):298-303, 1989 Mar 6 - Who cited this? | PubMed ID: 2566357 | Fulltext

Sympathetic activation of lipid synthesis in brown adipose tissue in the rat.

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Minokoshi Y, Saito M, and Shimazu T

The Journal of physiology 398:361-70, 1988 Apr - Who cited this? | PubMed ID: 3392678 | Fulltext

Ventromedial hypothalamic stimulation accelerates norepinephrine turnover in brown adipose tissue of rats.

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Saito M, Minokoshi Y, and Shimazu T

Life sciences 41(2):193-7, 1987 Jul 13 - Who cited this? | PubMed ID: 2885704 | Fulltext

Sympathetic denervation impairs responses of brown adipose tissue to VMH stimulation.

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Minokoshi Y, Saito M, and Shimazu T

The American journal of physiology 251(5 Pt 2):R1005-8, 1986 Nov - Who cited this? | PubMed ID: 3777207 | Fulltext

Metabolic and morphological alterations of brown adipose tissue after sympathetic denervation in rats.

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Minokoshi Y, Saito M, and Shimazu T

Journal of the autonomic nervous system 15(3):197-204, 1986 Mar - Who cited this? | PubMed ID: 3958437 | Fulltext

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