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Papers authored by Mills KH

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A novel anti-inflammatory role of NCAM-derived mimetic peptide, FGL.

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Downer EJ, Cowley TR, Lyons A, Mills KH, Berezin V, Bock E, and Lynch MA

Neurobiology of aging 31(1):118-28, 2010 Jan - Who cited this? | PubMed ID: 18468731 | Fulltext

Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide.

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Lyons A, McQuillan K, Deighan BF, O'Reilly JA, Downer EJ, Murphy AC, Watson M, Piazza A, O'Connell F, Griffin R, Mills KH, and Lynch MA

Brain, behavior, and immunity 23(7):1020-7, 2009 Oct - Who cited this? | PubMed ID: 19501645 | Fulltext

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

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Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, and Mills KH

Immunity 31(2):331-41, 2009 Aug 21 - Who cited this? | PubMed ID: 19682929 | Fulltext

Inhibition of ERK MAPK suppresses IL-23- and IL-1-driven IL-17 production and attenuates autoimmune disease.

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Brereton CF, Sutton CE, Lalor SJ, Lavelle EC, and Mills KH

Journal of immunology (Baltimore, Md. : 1950) 183(3):1715-23, 2009 Aug 1 - Who cited this? | PubMed ID: 19570828 | Fulltext

Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses.

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Walsh KP, Brady MT, Finlay CM, Boon L, and Mills KH

Journal of immunology (Baltimore, Md. : 1950) 183(3):1577-86, 2009 Aug 1 - Who cited this? | PubMed ID: 19587018 | Fulltext

CD11c+CD8{alpha}+ Dendritic Cells Promote Protective Immunity to Respiratory Infection with Bordetella pertussis.

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Dunne PJ, Moran B, Cummins RC, and Mills KH

Journal of immunology (Baltimore, Md. : 1950) 183(1):400-10, 2009 Jul 1 - Who cited this? | PubMed ID: 19542451 | Fulltext

Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet.

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de Roos B, Rungapamestry V, Ross K, Rucklidge G, Reid M, Duncan G, Horgan G, Toomey S, Browne J, Loscher CE, Mills KH, and Roche HM

Proteomics 9(12):3244-56, 2009 Jun - Who cited this? | PubMed ID: 19562798 | Fulltext

Psychological stress suppresses innate IFN-gamma production via glucocorticoid receptor activation: reversal by the anxiolytic chlordiazepoxide.

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Curtin NM, Boyle NT, Mills KH, and Connor TJ

Brain, behavior, and immunity 23(4):535-47, 2009 May - Who cited this? | PubMed ID: 19217938 | Fulltext

Psychological stress increases expression of IL-10 and its homolog IL-19 via beta-adrenoceptor activation: reversal by the anxiolytic chlordiazepoxide.

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Curtin NM, Mills KH, and Connor TJ

Brain, behavior, and immunity 23(3):371-9, 2009 Mar - Who cited this? | PubMed ID: 19159673 | Fulltext

Designer adjuvants for enhancing the efficacy of infectious disease and cancer vaccines based on suppression of regulatory T cell induction.

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Mills KH

Immunology letters 122(2):108-11, 2009 Feb 21 - Who cited this? | PubMed ID: 19100777 | Fulltext

Hepatitis C Virus-Specific Th17 Cells Are Suppressed by Virus-Induced TGF-{beta}.

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Rowan AG, Fletcher JM, Ryan EJ, Moran B, Hegarty JE, O'Farrelly C, and Mills KH

Journal of immunology (Baltimore, Md. : 1950) 181(7):4485-94, 2008 Oct 1 - Who cited this? | PubMed ID: 18802051 | Fulltext

TLR9 turns the tide on Treg cells.

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Mills KH

Immunity 29(4):518-20, 2008 Oct - Who cited this? | PubMed ID: 18957263 | Fulltext

Induction, function and regulation of IL-17-producing T cells.

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Mills KH

European journal of immunology 38(10):2636-49, 2008 Oct - Who cited this? | PubMed ID: 18958872 | Fulltext

Adenylate cycalse toxin of Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells.

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Hickey FB, Brereton CF, and Mills KH

Journal of leukocyte biology 84(1):234, 2008 Jul - Who cited this? | PubMed ID: 18401006 | Fulltext

IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8.

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Costelloe C, Watson M, Murphy A, McQuillan K, Loscher C, Armstrong ME, Garlanda C, Mantovani A, O'Neill LA, Mills KH, and Lynch MA

Journal of neurochemistry 105(5):1960-9, 2008 May - Who cited this? | PubMed ID: 18284608 | Fulltext

Therapeutic vaccination with dendritic cells pulsed with tumor-derived Hsp70 and a COX-2 inhibitor induces protective immunity against B16 melanoma.

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Toomey D, Conroy H, Jarnicki AG, Higgins SC, Sutton C, and Mills KH

Vaccine, 2008 Apr 24 - Who cited this? | PubMed ID: 18479787 | Fulltext

Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics.

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Jarnicki AG, Conroy H, Brereton C, Donnelly G, Toomey D, Walsh K, Sweeney C, Leavy O, Fletcher J, Lavelle EC, Dunne P, and Mills KH

Journal of immunology (Baltimore, Md. : 1950) 180(6):3797, 2008 Mar 15 - Who cited this? | PubMed ID: 18322186 | Fulltext

Bordetella pertussis expresses a functional type III secretion system that subverts protective innate and adaptive immune responses.

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Fennelly NK, Sisti F, Higgins SC, Ross PJ, van der Heide H, Mooi FR, Boyd A, and Mills KH

Infection and immunity 76(3):1257, 2008 Mar - Who cited this? | PubMed ID: 18195025 | Fulltext

TLR ligand suppression or enhancement of Treg cells? A double-edged sword in immunity to tumours.

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Conroy H, Marshall NA, and Mills KH

Oncogene 27(2):168-80, 2008 Jan 7 - Who cited this? | PubMed ID: 18176598 | Fulltext

Reciprocal effects of Th1 and Treg cell inducing pathogen-associated immunomodulatory molecules on anti-tumor immunity.

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Lysaght J, Jarnicki AG, and Mills KH

Cancer immunology, immunotherapy : CII 56(9):1367-79, 2007 Sep - Who cited this? | PubMed ID: 17279412 | Fulltext

CD200 ligand receptor interaction modulates microglial activation in vivo and in vitro: a role for IL-4.

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Lyons A, Downer EJ, Crotty S, Nolan YM, Mills KH, and Lynch MA

The Journal of neuroscience : the official journal of the Society for Neuroscience 27(31):8309-13, 2007 Aug 1 - Who cited this? | PubMed ID: 17670977 | Fulltext

Collapse of a fish population after exposure to a synthetic estrogen.

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Kidd KA, Blanchfield PJ, Mills KH, Palace VP, Evans RE, Lazorchak JM, and Flick RW

Proceedings of the National Academy of Sciences of the United States of America 104(21):8897-901, 2007 May 22 - Who cited this? | PubMed ID: 17517636 | Fulltext

Prevention of experimental colitis by parenteral administration of a pathogen-derived immunomodulatory molecule.

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Braat H, McGuirk P, Ten Kate FJ, Huibregtse I, Dunne PJ, Hommes DW, Van Deventer SJ, and Mills KH

Gut 56(3):351-7, 2007 Mar - Who cited this? | PubMed ID: 16952913 | Fulltext

TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.

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Higgins SC, Jarnicki AG, Lavelle EC, and Mills KH

Journal of immunology (Baltimore, Md. : 1950) 177(11):7980, 2006 Dec 1 - Who cited this? | PubMed ID: 17114471 | Fulltext

Suppression of antitumor immunity by IL-10 and TGF-beta-producing T cells infiltrating the growing tumor: influence of tumor environment on the induction of CD4+ and CD8+ regulatory T cells.

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Jarnicki AG, Lysaght J, Todryk S, and Mills KH

Journal of immunology (Baltimore, Md. : 1950) 177(2):896-904, 2006 Jul 15 - Who cited this? | PubMed ID: 16818744 | Fulltext

A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

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Sutton C, Brereton C, Keogh B, Mills KH, and Lavelle EC

The Journal of experimental medicine 203(7):1685-91, 2006 Jul 10 - Who cited this? | PubMed ID: 16818675 | Fulltext

Phase I evaluation of intranasal trivalent inactivated influenza vaccine with nontoxigenic Escherichia coli enterotoxin and novel biovector as mucosal adjuvants, using adult volunteers.

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Stephenson I, Zambon MC, Rudin A, Colegate A, Podda A, Bugarini R, Del Giudice G, Minutello A, Bonnington S, Holmgren J, Mills KH, and Nicholson KG

Journal of virology 80(10):4962-70, 2006 May - Who cited this? | PubMed ID: 16641287 | Fulltext

Biochemical and histopathological effects in pearl dace (Margariscus margarita) chronically exposed to a synthetic estrogen in a whole lake experiment.

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Palace VP, Wautier KG, Evans RE, Blanchfield PJ, Mills KH, Chalanchuk SM, Godard D, McMaster ME, Tetreault GR, Peters LE, Vandenbyllaardt L, and Kidd KA

Environmental toxicology and chemistry / SETAC 25(4):1114-25, 2006 Apr - Who cited this? | PubMed ID: 16629151 | Fulltext

Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity.

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Lipinski KS, Pelech S, Mountain A, Irvine AS, Kraaij R, Bangma CH, Mills KH, and Todryk SM

Cancer immunology, immunotherapy : CII 55(3):347-54, 2006 Mar - Who cited this? | PubMed ID: 16075195 | Fulltext

Induction of protective serum meningococcal bactericidal and diphtheria-neutralizing antibodies and mucosal immunoglobulin A in volunteers by nasal insufflations of the Neisseria meningitidis serogroup C polysaccharide-CRM197 conjugate vaccine mixed with chitosan.

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Huo Z, Sinha R, McNeela EA, Borrow R, Giemza R, Cosgrove C, Heath PT, Mills KH, Rappuoli R, Griffin GE, and Lewis DJ

Infection and immunity 73(12):8256-65, 2005 Dec - Who cited this? | PubMed ID: 16299322 | Fulltext

Proinflammatory responses in the murine brain after intranasal delivery of cholera toxin: implications for the use of AB toxins as adjuvants in intranasal vaccines.

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Armstrong ME, Lavelle EC, Loscher CE, Lynch MA, and Mills KH

The Journal of infectious diseases 192(9):1628-33, 2005 Nov 1 - Who cited this? | PubMed ID: 16206078 | Fulltext

Conjugated linoleic acid suppresses NF-kappa B activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction.

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Loscher CE, Draper E, Leavy O, Kelleher D, Mills KH, and Roche HM

Journal of immunology (Baltimore, Md. : 1950) 175(8):4990-8, 2005 Oct 15 - Who cited this? | PubMed ID: 16210601 | Fulltext

Stable plastid transformation in lettuce (Lactuca sativa L.).

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Lelivelt CL, McCabe MS, Newell CA, Desnoo CB, van Dun KM, Birch-Machin I, Gray JC, Mills KH, and Nugent JM

Plant molecular biology 58(6):763-74, 2005 Aug - Who cited this? | PubMed ID: 16240172 | Fulltext

Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and enzymatic activity in immunomodulation and cell death.

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Boyd AP, Ross PJ, Conroy H, Mahon N, Lavelle EC, and Mills KH

Journal of immunology (Baltimore, Md. : 1950) 175(2):730-8, 2005 Jul 15 - Who cited this? | PubMed ID: 16002668 | Fulltext

Novel mechanism of immunosuppression by influenza virus haemagglutinin: selective suppression of interleukin 12 p35 transcription in murine bone marrow-derived dendritic cells.

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Noone CM, Lewis EA, Frawely AB, Newman RW, Mahon BP, Mills KH, and Johnson PA

The Journal of general virology 86(Pt 7):1885-90, 2005 Jul - Who cited this? | PubMed ID: 15958666 | Fulltext

Role of interleukin-4 in regulation of age-related inflammatory changes in the hippocampus.

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Nolan Y, Maher FO, Martin DS, Clarke RM, Brady MT, Bolton AE, Mills KH, and Lynch MA

The Journal of biological chemistry 280(10):9354-62, 2005 Mar 11 - Who cited this? | PubMed ID: 15615726 | Fulltext

Innate IL-10 promotes the induction of Th2 responses with plasmid DNA expressing HIV gp120.

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Daly LM, Johnson PA, Donnelly G, Nicolson C, Robertson J, and Mills KH

Vaccine 23(7):963-74, 2005 Jan 4 - Who cited this? | PubMed ID: 15603899 | Fulltext

Regulatory cells and the control of respiratory infection.

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McGuirk P, Higgins SC, and Mills KH

Current allergy and asthma reports 5(1):51-5, 2005 Jan - Who cited this? | PubMed ID: 15659263 | Fulltext

Regulatory T cells: friend or foe in immunity to infection?.

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Mills KH

Nature reviews. Immunology 4(11):841-55, 2004 Nov - Who cited this? | PubMed ID: 15516964 | Fulltext

Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen-specific Th1 and enhancement of Th2, but not Tr1 cells.

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Byrne P, McGuirk P, Todryk S, and Mills KH

European journal of immunology 34(9):2579-88, 2004 Sep - Who cited this? | PubMed ID: 15307190 | Fulltext

Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin.

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Bowe F, Lavelle EC, McNeela EA, Hale C, Clare S, Arico B, Giuliani MM, Rae A, Huett A, Rappuoli R, Dougan G, and Mills KH

Infection and immunity 72(7):4052-60, 2004 Jul - Who cited this? | PubMed ID: 15213150 | Fulltext

Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent.

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Lavelle EC, Jarnicki A, McNeela E, Armstrong ME, Higgins SC, Leavy O, and Mills KH

Journal of leukocyte biology 75(5):756-63, 2004 May - Who cited this? | PubMed ID: 14704372 | Fulltext

Antigen-specific regulatory T cells--their induction and role in infection.

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Mills KH and McGuirk P

Seminars in immunology 16(2):107-17, 2004 Apr - Who cited this? | PubMed ID: 15036234 | Fulltext

Adenylate cyclase toxin from Bordetella pertussis synergizes with lipopolysaccharide to promote innate interleukin-10 production and enhances the induction of Th2 and regulatory T cells.

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Ross PJ, Lavelle EC, Mills KH, and Boyd AP

Infection and immunity 72(3):1568-79, 2004 Mar - Who cited this? | PubMed ID: 14977963 | Fulltext

Intranasal immunization with genetically detoxified diphtheria toxin induces T cell responses in humans: enhancement of Th2 responses and toxin-neutralizing antibodies by formulation with chitosan.

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McNeela EA, Jabbal-Gill I, Illum L, Pizza M, Rappuoli R, Podda A, Lewis DJ, and Mills KH

Vaccine 22(8):909-14, 2004 Feb 25 - Who cited this? | PubMed ID: 15161067 | Fulltext

Molecules of infectious agents as immunomodulatory drugs.

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Lavelle EC, McGuirk P, and Mills KH

Current topics in medicinal chemistry 4(5):499-508, 2004 - Who cited this? | PubMed ID: 14965301 | Fulltext

Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes.

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Brady MT, MacDonald AJ, Rowan AG, and Mills KH

European journal of immunology 33(12):3448-57, 2003 Dec - Who cited this? | PubMed ID: 14635055 | Fulltext

Role of interferon-gamma and nitric oxide in the neuropathogenesis of avirulent Semliki Forest virus infection.

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Keogh B, Atkins GJ, Mills KH, and Sheahan BJ

Neuropathology and applied neurobiology 29(6):553-62, 2003 Dec - Who cited this? | PubMed ID: 14636162 | Fulltext

Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology.

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Higgins SC, Lavelle EC, McCann C, Keogh B, McNeela E, Byrne P, O'Gorman B, Jarnicki A, McGuirk P, and Mills KH

Journal of immunology (Baltimore, Md. : 1950) 171(6):3119-27, 2003 Sep 15 - Who cited this? | PubMed ID: 12960338 | Fulltext

Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation.

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Lavelle EC, McNeela E, Armstrong ME, Leavy O, Higgins SC, and Mills KH

Journal of immunology (Baltimore, Md. : 1950) 171(5):2384-92, 2003 Sep 1 - Who cited this? | PubMed ID: 12928385 | Fulltext

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