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Papers authored by Mello CC

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Distinct Argonaute-Mediated 22G-RNA Pathways Direct Genome Surveillance in the C. elegans Germline.

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Gu W, Shirayama M, Conte D, Vasale J, Batista PJ, Claycomb JM, Moresco JJ, Youngman EM, Keys J, Stoltz MJ, Chen CC, Chaves DA, Duan S, Kasschau KD, Fahlgren N, Yates JR,

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Molecular cell 36(2):231-44, 2009 Oct 23 - Who cited this? | PubMed ID: 19800275 | Fulltext

The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation.

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Claycomb JM, Batista PJ, Pang KM, Gu W, Vasale JJ, van Wolfswinkel JC, Chaves DA, Shirayama M, Mitani S, Ketting RF, Conte D, and Mello CC

Cell 139(1):123-34, 2009 Oct 2 - Who cited this? | PubMed ID: 19804758 | Fulltext

CDE-1 affects chromosome segregation through uridylation of CSR-1-bound siRNAs.

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van Wolfswinkel JC, Claycomb JM, Batista PJ, Mello CC, Berezikov E, and Ketting RF

Cell 139(1):135-48, 2009 Oct 2 - Who cited this? | PubMed ID: 19804759 | Fulltext

Chromatin-associated periodicity in genetic variation downstream of transcriptional start sites.

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Sasaki S, Mello CC, Shimada A, Nakatani Y, Hashimoto S, Ogawa M, Matsushima K, Gu SG, Kasahara M, Ahsan B, Sasaki A, Saito T, Suzuki Y, Sugano S, Kohara Y, Takeda H,

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Science (New York, N.Y.) 323(5912):401-4, 2009 Jan 16 - Who cited this? | PubMed ID: 19074313 | Fulltext

The time to demand funding.

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Mello CC and Walsh JV

Science (New York, N.Y.) 323(5911):208, 2009 Jan 9 - Who cited this? | PubMed ID: 19131609 | Fulltext

PRG-1 and 21U-RNAs Interact to Form the piRNA Complex Required for Fertility in C. elegans.

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Batista PJ, Ruby JG, Claycomb JM, Chiang R, Fahlgren N, Kasschau KD, Chaves DA, Gu W, Vasale JJ, Duan S, Conte D, Luo S, Schroth GP, Carrington JC, Bartel DP, and Mello CC

Molecular cell, 2008 Jun 18 - Who cited this? | PubMed ID: 18571452 | Fulltext

Return to the RNAi world: rethinking gene expression and evolution.

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Mello CC

Cell death and differentiation 14(12):2013, 2007 Dec - Who cited this? | PubMed ID: 18007672 | Fulltext

A conversation with Craig C Mello on the discovery of RNAi.

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Mello CC

Cell death and differentiation 14(12):1981-4, 2007 Dec - Who cited this? | PubMed ID: 18007669 | Fulltext

Return to the RNAi world: rethinking gene expression and evolution (Nobel Lecture).

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Mello CC

Angewandte Chemie (International ed. in English) 46(37):6985-94, 2007 - Who cited this? | PubMed ID: 17712806 | Fulltext

Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi.

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Yigit E, Batista PJ, Bei Y, Pang KM, Chen CC, Tolia NH, Joshua-Tor L, Mitani S, Simard MJ, and Mello CC

Cell 127(4):747, 2006 Nov 17 - Who cited this? | PubMed ID: 17110334 | Fulltext

Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways.

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Duchaine TF, Wohlschlegel JA, Kennedy S, Bei Y, Conte D, Pang K, Brownell DR, Harding S, Mitani S, Ruvkun G, Yates JR, and Mello CC

Cell 124(2):343, 2006 Jan 27 - Who cited this? | PubMed ID: 16439208 | Fulltext

The Conserved Kinases CDK-1, GSK-3, KIN-19, and MBK-2 Promote OMA-1 Destruction to Regulate the Oocyte-to-Embryo Transition in C. elegans.

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Shirayama M, Soto MC, Ishidate T, Kim S, Nakamura K, Bei Y, van den Heuvel S, and Mello CC

Current biology : CB 16(1):47, 2006 Jan 10 - Who cited this? | PubMed ID: 16343905 | Fulltext

Experimental characterization of the folding kinetics of the notch ankyrin domain.

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Mello CC, Bradley CM, Tripp KW, and Barrick D

Journal of molecular biology 352(2):266-81, 2005 Sep 16 - Who cited this? | PubMed ID: 16095609 | Fulltext

Wnt signaling drives WRM-1/beta-catenin asymmetries in early C. elegans embryos.

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Nakamura K, Kim S, Ishidate T, Bei Y, Pang K, Shirayama M, Trzepacz C, Brownell DR, and Mello CC

Genes & development 19(15):1749-54, 2005 Aug 1 - Who cited this? | PubMed ID: 16077004 | Fulltext

Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants.

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Wang D, Kennedy S, Conte D, Kim JK, Gabel HW, Kamath RS, Mello CC, and Ruvkun G

Nature 436(7050):593-7, 2005 Jul 28 - Who cited this? | PubMed ID: 16049496 | Fulltext

A member of the polymerase beta nucleotidyltransferase superfamily is required for RNA interference in C. elegans.

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Chen CC, Simard MJ, Tabara H, Brownell DR, McCollough JA, and Mello CC

Current biology : CB 15(4):378, 2005 Feb 22 - Who cited this? | PubMed ID: 15723801 | Fulltext

RDE-2 interacts with MUT-7 to mediate RNA interference in Caenorhabditis elegans.

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Tops BB, Tabara H, Sijen T, Simmer F, Mello CC, Plasterk RH, and Ketting RF

Nucleic acids research 33(1):347-55, 2005 - Who cited this? | PubMed ID: 15653635 | Fulltext

Micromanaging insulin secretion.

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Mello CC and Czech MP

Nature medicine 10(12):1297-8, 2004 Dec - Who cited this? | PubMed ID: 15580250 | Fulltext

The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins.

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Grigorenko AP, Moliaka YK, Soto MC, Mello CC, and Rogaev EI

Proceedings of the National Academy of Sciences of the United States of America 101(41):14955-60, 2004 Oct 12 - Who cited this? | PubMed ID: 15469912 | Fulltext

An experimentally determined protein folding energy landscape.

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Mello CC and Barrick D

Proceedings of the National Academy of Sciences of the United States of America 101(39):14102-7, 2004 Sep 28 - Who cited this? | PubMed ID: 15377792 | Fulltext

Revealing the world of RNA interference.

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Mello CC and Conte D

Nature 431(7006):338-42, 2004 Sep 16 - Who cited this? | PubMed ID: 15372040 | Fulltext

Sequence-specific inhibition of small RNA function.

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Hutvágner G, Simard MJ, Mello CC, and Zamore PD

PLoS biology 2(4), 2004 Apr - Who cited this? | PubMed ID: 15024405 | Fulltext

The minibrain kinase homolog, mbk-2, is required for spindle positioning and asymmetric cell division in early C. elegans embryos.

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Pang KM, Ishidate T, Nakamura K, Shirayama M, Trzepacz C, Schubert CM, Priess JR, and Mello CC

Developmental biology 265(1):127, 2004 Jan 1 - Who cited this? | PubMed ID: 14697358 | Fulltext

Chromatin regulation during C. elegans germline development.

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Shin TH and Mello CC

Current opinion in genetics & development 13(5):455, 2003 Oct - Who cited this? | PubMed ID: 14550409 | Fulltext

Functional conservation between members of an ancient duplicated transcription factor family, LSF/Grainyhead.

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Venkatesan K, McManus HR, Mello CC, Smith TF, and Hansen U

Nucleic acids research 31(15):4304-16, 2003 Aug 1 - Who cited this? | PubMed ID: 12888489 | Fulltext

Measuring the stability of partly folded proteins using TMAO.

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Mello CC and Barrick D

Protein science : a publication of the Protein Society 12(7):1522-9, 2003 Jul - Who cited this? | PubMed ID: 12824497 | Fulltext

Inducible systemic RNA silencing in Caenorhabditis elegans.

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Timmons L, Tabara H, Mello CC, and Fire AZ

Molecular biology of the cell 14(7):2972-83, 2003 Jul - Who cited this? | PubMed ID: 12857879 | Fulltext

RNA interference in caenorhabditis elegans.

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Conte D and Mello CC

Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] Chapter 26:Unit26.3, 2003 May - Who cited this? | PubMed ID: 18265327 | Fulltext

MEP-1 and a homolog of the NURD complex component Mi-2 act together to maintain germline-soma distinctions in C. elegans.

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Unhavaithaya Y, Shin TH, Miliaras N, Lee J, Oyama T, and Mello CC

Cell 111(7):991, 2002 Dec 27 - Who cited this? | PubMed ID: 12507426 | Fulltext

SRC-1 and Wnt signaling act together to specify endoderm and to control cleavage orientation in early C. elegans embryos.

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Bei Y, Hogan J, Berkowitz LA, Soto M, Rocheleau CE, Pang KM, Collins J, and Mello CC

Developmental cell 3(1):113-25, 2002 Jul - Who cited this? | PubMed ID: 12110172 | Fulltext

The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans.

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Tabara H, Yigit E, Siomi H, and Mello CC

Cell 109(7):861, 2002 Jun 28 - Who cited this? | PubMed ID: 12110183 | Fulltext

The GEX-2 and GEX-3 proteins are required for tissue morphogenesis and cell migrations in C. elegans.

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Soto MC, Qadota H, Kasuya K, Inoue M, Tsuboi D, Mello CC, and Kaibuchi K

Genes & development 16(5):620-32, 2002 Mar 1 - Who cited this? | PubMed ID: 11877381 | Fulltext

RNAi (Nematodes: Caenorhabditis elegans).

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Grishok A and Mello CC

Advances in genetics 46:339-60, 2002 - Who cited this? | PubMed ID: 11931230 | Fulltext

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing.

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Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, Baillie DL, Fire A, Ruvkun G, and Mello CC

Cell 106(1):23, 2001 Jul 13 - Who cited this? | PubMed ID: 11461699 | Fulltext

Genetic requirements for inheritance of RNAi in C. elegans.

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Grishok A, Tabara H, and Mello CC

Science (New York, N.Y.) 287(5462):2494-7, 2000 Mar 31 - Who cited this? | PubMed ID: 10741970 | Fulltext

Structural correlates for enhanced stability in the E2 DNA-binding domain from bovine papillomavirus.

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Veeraraghavan S, Mello CC, Androphy EJ, and Baleja JD

Biochemistry 38(49):16115-24, 1999 Dec 7 - Who cited this? | PubMed ID: 10587434 | Fulltext

The rde-1 gene, RNA interference, and transposon silencing in C. elegans.

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Tabara H, Sarkissian M, Kelly WG, Fleenor J, Grishok A, Timmons L, Fire A, and Mello CC

Cell 99(2):123, 1999 Oct 15 - Who cited this? | PubMed ID: 10535731 | Fulltext

MOM-4, a MAP kinase kinase kinase-related protein, activates WRM-1/LIT-1 kinase to transduce anterior/posterior polarity signals in C. elegans.

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Shin TH, Yasuda J, Rocheleau CE, Lin R, Soto M, Bei Y, Davis RJ, and Mello CC

Molecular cell 4(2):275-80, 1999 Aug - Who cited this? | PubMed ID: 10488343 | Fulltext

WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans.

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Rocheleau CE, Yasuda J, Shin TH, Lin R, Sawa H, Okano H, Priess JR, Davis RJ, and Mello CC

Cell 97(6):717-26, 1999 Jun 11 - Who cited this? | PubMed ID: 10380924 | Fulltext

pos-1 encodes a cytoplasmic zinc-finger protein essential for germline specification in C. elegans.

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Tabara H, Hill RJ, Mello CC, Priess JR, and Kohara Y

Development (Cambridge, England) 126(1):1, 1999 Jan - Who cited this? | PubMed ID: 9834181 | Fulltext

RNAi in C. elegans: soaking in the genome sequence.

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Tabara H, Grishok A, and Mello CC

Science (New York, N.Y.) 282(5388):430-1, 1998 Oct 16 - Who cited this? | PubMed ID: 9841401 | Fulltext

1H, 15N, and 13C NMR resonance assignments for the DNA-binding domain of the BPV-1 E2 protein.

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Veeraraghavan S, Mello CC, Lee KM, Androphy EJ, and Baleja JD

Journal of biomolecular NMR 11(4):457-8, 1998 May - Who cited this? | PubMed ID: 9691287 | Fulltext

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans.

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Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, and Mello CC

Nature 391(6669):806, 1998 Feb 19 - Who cited this? | PubMed ID: 9486653 | Fulltext

Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos.

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Rocheleau CE, Downs WD, Lin R, Wittmann C, Bei Y, Cha YH, Ali M, Priess JR, and Mello CC

Cell 90(4):707-16, 1997 Aug 22 - Who cited this? | PubMed ID: 9288750 | Fulltext

MEX-3 is a KH domain protein that regulates blastomere identity in early C. elegans embryos.

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Draper BW, Mello CC, Bowerman B, Hardin J, and Priess JR

Cell 87(2):205-16, 1996 Oct 18 - Who cited this? | PubMed ID: 8861905 | Fulltext

par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3.

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Watts JL, Etemad-Moghadam B, Guo S, Boyd L, Draper BW, Mello CC, Priess JR, and Kemphues KJ

Development (Cambridge, England) 122(10):3133, 1996 Oct - Who cited this? | PubMed ID: 8898226 | Fulltext

Repression of gene expression in the embryonic germ lineage of C. elegans.

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Seydoux G, Mello CC, Pettitt J, Wood WB, Priess JR, and Fire A

Nature 382(6593):713, 1996 Aug 22 - Who cited this? | PubMed ID: 8751441 | Fulltext

The PIE-1 protein and germline specification in C. elegans embryos.

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Mello CC, Schubert C, Draper B, Zhang W, Lobel R, and Priess JR

Nature 382(6593):710, 1996 Aug 22 - Who cited this? | PubMed ID: 8751440 | Fulltext

An inductive interaction in 4-cell stage C. elegans embryos involves APX-1 expression in the signalling cell.

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Mickey KM, Mello CC, Montgomery MK, Fire A, and Priess JR

Development (Cambridge, England) 122(6):1791, 1996 Jun - Who cited this? | PubMed ID: 8674418 | Fulltext

par-2, a gene required for blastomere asymmetry in Caenorhabditis elegans, encodes zinc-finger and ATP-binding motifs.

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Levitan DJ, Boyd L, Mello CC, Kemphues KJ, and Stinchcomb DT

Proceedings of the National Academy of Sciences of the United States of America 91(13):6108-12, 1994 Jun 21 - Who cited this? | PubMed ID: 8016123 | Fulltext

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