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Papers authored by Mellins ED

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Oligoarticular and polyarticular JIA: epidemiology and pathogenesis.

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Macaubas C, Nguyen K, Milojevic D, Park JL, and Mellins ED

Nature reviews. Rheumatology 5(11):616-26, 2009 Nov - Who cited this? | PubMed ID: 19806151 | Fulltext

Breaking old paradigms: Th17 cells in autoimmune arthritis.

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Peck A and Mellins ED

Clinical immunology (Orlando, Fla.) 132(3):295-304, 2009 Sep - Who cited this? | PubMed ID: 19403336 | Fulltext

T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides.

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Harkiolaki M, Holmes SL, Svendsen P, Gregersen JW, Jensen LT, McMahon R, Friese MA, van Boxel G, Etzensperger R, Tzartos JS, Kranc K, Sainsbury S, Harlos K, Mellins ED, Palace J, Esiri MM,

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Immunity 30(3):348-57, 2009 Mar - Who cited this? | PubMed ID: 19303388 | Fulltext

Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM.

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Fallang LE, Roh S, Holm A, Bergseng E, Yoon T, Fleckenstein B, Bandyopadhyay A, Mellins ED, and Sollid LM

Journal of immunology (Baltimore, Md. : 1950) 181(8):5451-61, 2008 Oct 15 - Who cited this? | PubMed ID: 18832702 | Fulltext

Modulation of peripheral B cell tolerance by CD72 in a murine model.

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Li DH, Winslow MM, Cao TM, Chen AH, Davis CR, Mellins ED, Utz PJ, Crabtree GR, and Parnes JR

Arthritis and rheumatism 58(10):3192-3204, 2008 Sep 29 - Who cited this? | PubMed ID: 18821699 | Fulltext

Research priorities in pediatric rheumatology: The Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus.

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Ota S, Cron RQ, Schanberg LE, O'Neil K, Mellins ED, Fuhlbrigge RC, and Feldman BM

Pediatric rheumatology online journal 6:5, 2008 - Who cited this? | PubMed ID: 18380905 | Fulltext

Regulatory T cells and their role in rheumatic diseases: a potential target for novel therapeutic development.

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Milojevic D, Nguyen KD, Wara D, and Mellins ED

Pediatric rheumatology online journal 6:20, 2008 - Who cited this? | PubMed ID: 19046457 | Fulltext

Posttranslational regulation of I-Ed by affinity for CLIP.

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Rinderknecht CH, Belmares MP, Catanzarite TL, Bankovich AJ, Holmes TH, Garcia KC, Nanda NK, Busch R, Kovats S, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 179(9):5907, 2007 Nov 1 - Who cited this? | PubMed ID: 17947664 | Fulltext

Influenza A virus elevates active cathepsin B in primary murine DC.

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Burster T, Giffon T, Dahl ME, Björck P, Bogyo M, Weber E, Mahmood K, Lewis DB, and Mellins ED

International immunology 19(5):645-55, 2007 May - Who cited this? | PubMed ID: 17446210 | Fulltext

Clinical research networks: a step towards evidence-based practice in pediatric rheumatology.

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Mellins ED and Rider LG

Nature clinical practice. Rheumatology 3(2):59, 2007 Feb - Who cited this? | PubMed ID: 17299440 | Fulltext

Candidate early predictors for progression to joint damage in systemic juvenile idiopathic arthritis.

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Sandborg C, Holmes TH, Lee T, Biederman K, Bloch DA, Emery H, McCurdy D, and Mellins ED

The Journal of rheumatology 33(11):2322-9, 2006 Nov - Who cited this? | PubMed ID: 16960920 | Fulltext

Human cytomegalovirus alters localization of MHC class II and dendrite morphology in mature Langerhans cells.

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Lee AW, Hertel L, Louie RK, Burster T, Lacaille V, Pashine A, Abate DA, Mocarski ES, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 177(6):3960-71, 2006 Sep 15 - Who cited this? | PubMed ID: 16951359 | Fulltext

DRB1*0401-restricted human T cell clone specific for the major proinsulin73-90 epitope expresses a down-regulatory T helper 2 phenotype.

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Durinovic-Belló I, Rosinger S, Olson JA, Congia M, Ahmad RC, Rickert M, Hampl J, Kalbacher H, Drijfhout JW, Mellins ED, Al Dahouk S, Kamradt T, Maeurer MJ, Nhan C, Roep BO, Boehm BO,

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Proceedings of the National Academy of Sciences of the United States of America 103(31):11683-8, 2006 Aug 1 - Who cited this? | PubMed ID: 16868084 | Fulltext

Medicine on a need-to-know basis.

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Busch R, Byrne B, Gandrud L, Sears D, Meyer E, Kattah M, Kurihara C, Haertel E, Parnes JR, and Mellins ED

Nature immunology 7(6):543-7, 2006 Jun - Who cited this? | PubMed ID: 16715061 | Fulltext

Human dendritic cell expression of HLA-DO is subset specific and regulated by maturation.

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Hornell TM, Burster T, Jahnsen FL, Pashine A, Ochoa MT, Harding JJ, Macaubas C, Lee AW, Modlin RL, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 176(6):3536-47, 2006 Mar 15 - Who cited this? | PubMed ID: 16517722 | Fulltext

Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression.

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Busch R, Rinderknecht CH, Roh S, Lee AW, Harding JJ, Burster T, Hornell TM, and Mellins ED

Immunological reviews 207:242-60, 2005 Oct - Who cited this? | PubMed ID: 16181341 | Fulltext

Selective developmental defects of cord blood antigen-presenting cell subsets.

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Drohan L, Harding JJ, Holm B, Cordoba-Tongson E, Dekker CL, Holmes T, Maecker H, and Mellins ED

Human immunology 65(11):1356-69, 2004 Nov - Who cited this? | PubMed ID: 15556686 | Fulltext

Bordetella pertussis infection of primary human monocytes alters HLA-DR expression.

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Shumilla JA, Lacaille V, Hornell TM, Huang J, Narasimhan S, Relman DA, and Mellins ED

Infection and immunity 72(3):1450-62, 2004 Mar - Who cited this? | PubMed ID: 14977950 | Fulltext

Role of pediatric and internist rheumatologists in treating children with rheumatic diseases.

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Mayer ML, Sandborg CI, and Mellins ED

Pediatrics 113(3 Pt 1):e173-81, 2004 Mar - Who cited this? | PubMed ID: 14993573 | Fulltext

Access to pediatric rheumatology care in the United States.

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Mayer ML, Mellins ED, and Sandborg CI

Arthritis and rheumatism 49(6):759-65, 2003 Dec 15 - Who cited this? | PubMed ID: 14673961 | Fulltext

Regulation of the class II MHC pathway in primary human monocytes by granulocyte-macrophage colony-stimulating factor.

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Hornell TM, Beresford GW, Bushey A, Boss JM, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 171(5):2374-83, 2003 Sep 1 - Who cited this? | PubMed ID: 12928384 | Fulltext

Cytokines elicited by T cell epitopes from a synovial autoantigen: altered peptide ligands can reduce interferon-gamma and interleukin-10 production.

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Hall FC, Visconti KC, Ahmad RC, Parry SL, Miltenburg AM, McConnell HM, Mellins ED, and Sønderstrup G

Arthritis and rheumatism 48(8):2375-85, 2003 Aug - Who cited this? | PubMed ID: 12905493 | Fulltext

Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides.

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Pashine A, Busch R, Belmares MP, Munning JN, Doebele RC, Buckingham M, Nolan GP, and Mellins ED

Immunity 19(2):183-92, 2003 Aug - Who cited this? | PubMed ID: 12932352 | Fulltext

Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus.

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Hertel L, Lacaille VG, Strobl H, Mellins ED, and Mocarski ES

Journal of virology 77(13):7563-74, 2003 Jul - Who cited this? | PubMed ID: 12805456 | Fulltext

Point mutations in or near the antigen-binding groove of HLA-DR3 implicate class II-associated invariant chain peptide affinity as a constraint on MHC class II polymorphism.

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Doebele RC, Pashine A, Liu W, Zaller DM, Belmares M, Busch R, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 170(9):4683-92, 2003 May 1 - Who cited this? | PubMed ID: 12707347 | Fulltext

Formation of two peptide/MHC II isomers is catalyzed differentially by HLA-DM.

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Belmares MP, Busch R, Mellins ED, and McConnell HM

Biochemistry 42(3):838-47, 2003 Jan 28 - Who cited this? | PubMed ID: 12534297 | Fulltext

Structural factors contributing to DM susceptibility of MHC class II/peptide complexes.

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Belmares MP, Busch R, Wucherpfennig KW, McConnell HM, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 169(9):5109-17, 2002 Nov 1 - Who cited this? | PubMed ID: 12391227 | Fulltext

Latent cytomegalovirus down-regulates major histocompatibility complex class II expression on myeloid progenitors.

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Slobedman B, Mocarski ES, Arvin AM, Mellins ED, and Abendroth A

Blood 100(8):2867-73, 2002 Oct 15 - Who cited this? | PubMed ID: 12351397 | Fulltext

Labeling antigen-specific CD4(+) T cells with class II MHC oligomers.

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Cameron TO, Norris PJ, Patel A, Moulon C, Rosenberg ES, Mellins ED, Wedderburn LR, and Stern LJ

Journal of immunological methods 268(1):51-69, 2002 Oct 1 - Who cited this? | PubMed ID: 12213343 | Fulltext

Stabilization of soluble, low-affinity HLA-DM/HLA-DR1 complexes by leucine zippers.

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Busch R, Pashine A, Garcia KC, and Mellins ED

Journal of immunological methods 263(1-2):111-21, 2002 May 1 - Who cited this? | PubMed ID: 12009208 | Fulltext

Relationship between kinetic stability and immunogenicity of HLA-DR4/peptide complexes.

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Hall FC, Rabinowitz JD, Busch R, Visconti KC, Belmares M, Patil NS, Cope AP, Patel S, McConnell HM, Mellins ED, and Sonderstrup G

European journal of immunology 32(3):662-70, 2002 Mar - Who cited this? | PubMed ID: 11857340 | Fulltext

Rheumatoid arthritis (RA)-associated HLA-DR alleles form less stable complexes with class II-associated invariant chain peptide than non-RA-associated HLA-DR alleles.

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Patil NS, Pashine A, Belmares MP, Liu W, Kaneshiro B, Rabinowitz J, McConnell H, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 167(12):7157-68, 2001 Dec 15 - Who cited this? | PubMed ID: 11739539 | Fulltext

The kinetic basis of peptide exchange catalysis by HLA-DM.

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Zarutskie JA, Busch R, Zavala-Ruiz Z, Rushe M, Mellins ED, and Stern LJ

Proceedings of the National Academy of Sciences of the United States of America 98(22):12450-5, 2001 Oct 23 - Who cited this? | PubMed ID: 11606721 | Fulltext

Autoantigenic HCgp39 epitopes are presented by the HLA-DM-dependent presentation pathway in human B cells.

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Patil NS, Hall FC, Drover S, Spurrell DR, Bos E, Cope AP, Sonderstrup G, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 166(1):33-41, 2001 Jan 1 - Who cited this? | PubMed ID: 11123274 | Fulltext

pH stability of HLA-DR4 complexes with antigenic peptides.

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Belmares MP, Rabinowitz JD, Liu W, Mellins ED, and McConnell HM

Biochemistry 39(47):14558-66, 2000 Nov 28 - Who cited this? | PubMed ID: 11087411 | Fulltext

Determination of the HLA-DM interaction site on HLA-DR molecules.

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Doebele RC, Busch R, Scott HM, Pashine A, and Mellins ED

Immunity 13(4):517-27, 2000 Oct - Who cited this? | PubMed ID: 11070170 | Fulltext

Accessory molecules for MHC class II peptide loading.

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Busch R, Doebele RC, Patil NS, Pashine A, and Mellins ED

Current opinion in immunology 12(1):99-106, 2000 Feb - Who cited this? | PubMed ID: 10679402 | Fulltext

Secondary structure composition and pH-dependent conformational changes of soluble recombinant HLA-DM.

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Busch R, Reich Z, Zaller DM, Sloan V, and Mellins ED

The Journal of biological chemistry 273(42):27557-64, 1998 Oct 16 - Who cited this? | PubMed ID: 9765288 | Fulltext

DR/CLIP (class II-associated invariant chain peptides) and DR/peptide complexes colocalize in prelysosomes in human B lymphoblastoid cells.

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Stang E, Guerra CB, Amaya M, Paterson Y, Bakke O, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 160(10):4696-707, 1998 May 15 - Who cited this? | PubMed ID: 9590215 | Fulltext

Novel glycosylation of HLA-DRalpha disrupts antigen presentation without altering endosomal localization.

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Guerra CB, Busch R, Doebele RC, Liu W, Sawada T, Kwok WW, Chang MD, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 160(9):4289-97, 1998 May 1 - Who cited this? | PubMed ID: 9574531 | Fulltext

Aberrant intermolecular disulfide bonding in a mutant HLA-DM molecule: implications for assembly, maturation, and function.

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Busch R, Doebele RC, von Scheven E, Fahrni J, and Mellins ED

Journal of immunology (Baltimore, Md. : 1950) 160(2):734-43, 1998 Jan 15 - Who cited this? | PubMed ID: 9551909 | Fulltext

Developing and shedding inhibitions: how MHC class II molecules reach maturity.

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Busch R and Mellins ED

Current opinion in immunology 8(1):51-8, 1996 Feb - Who cited this? | PubMed ID: 8729446 | Fulltext

Predicting remission in juvenile rheumatoid arthritis with methotrexate treatment.

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Wallace CA, Sherry DD, Mellins ED, and Aiken RP

The Journal of rheumatology 20(1):118-22, 1993 Jan - Who cited this? | PubMed ID: 8441141 | Fulltext

Eosinophilic fasciitis in children frequently progresses to scleroderma-like cutaneous fibrosis.

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Farrington ML, Haas JE, Nazar-Stewart V, and Mellins ED

The Journal of rheumatology 20(1):128-32, 1993 Jan - Who cited this? | PubMed ID: 8441144 | Fulltext

The role of the MHC in autoimmunity: an overview.

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Mellins ED

The Journal of rheumatology. Supplement 33:63-9, 1992 Apr - Who cited this? | PubMed ID: 1593605 | Fulltext

Decreasing severity of chronic uveitis in children with pauciarticular arthritis.

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Sherry DD, Mellins ED, and Wedgwood RJ

American journal of diseases of children (1960) 145(9):1026-8, 1991 Sep - Who cited this? | PubMed ID: 1877561 | Fulltext

Lymphocyte activation provokes modification of a lymphocyte-specific protein tyrosine kinase (p56lck).

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Marth JD, Lewis DB, Cooke MP, Mellins ED, Gearn ME, Samelson LE, Wilson CB, Miller AD, and Perlmutter RM

Journal of immunology (Baltimore, Md. : 1950) 142(7):2430-7, 1989 Apr 1 - Who cited this? | PubMed ID: 2784463 | Fulltext

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