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Papers authored by Mcguckin MA

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MUC1 Limits Helicobacter pylori Infection both by Steric Hindrance and by Acting as a Releasable Decoy.

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Lindén SK, Sheng YH, Every AL, Miles KM, Skoog EC, Florin TH, Sutton P, and McGuckin MA

PLoS pathogens 5(10):e1000617, 2009 Oct - Who cited this? | PubMed ID: 19816567 | Fulltext

Reduced mucin sulfonation and impaired intestinal barrier function in the hyposulfataemic NaS1 null mouse.

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Dawson PA, Huxley S, Gardiner B, Tran T, McAuley JL, Grimmond S, McGuckin MA, and Markovich D

Gut 58(7):910-9, 2009 Jul - Who cited this? | PubMed ID: 19201772 | Fulltext

Intestinal barrier dysfunction in inflammatory bowel diseases.

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McGuckin MA, Eri R, Simms LA, Florin TH, and Radford-Smith G

Inflammatory bowel diseases 15(1):100-13, 2009 Jan - Who cited this? | PubMed ID: 18623167 | Fulltext

Mucin 1 (MUC1) is a novel partner for MAL2 in breast carcinoma cells.

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Fanayan S, Shehata M, Agterof AP, McGuckin MA, Alonso MA, and Byrne JA

BMC cell biology 10:7, 2009 - Who cited this? | PubMed ID: 19175940 | Fulltext

Muc1 Limits Helicobacter felis Binding to Gastric Epithelial Cells But Does not Limit Colonization and Gastric Pathology Following Infection.

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Every AL, Chionh YT, Skene CD, McGuckin MA, and Sutton P

Helicobacter 13(6):489-93, 2008 Dec - Who cited this? | PubMed ID: 19166413 | Fulltext

Campylobacter jejuni response to human mucin MUC2: modulation of colonization and pathogenicity determinants.

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Tu QV, McGuckin MA, and Mendz GL

Journal of medical microbiology 57(Pt 7):795, 2008 Jul - Who cited this? | PubMed ID: 18566135 | Fulltext

Listeria monocytogenes internalins bind to the human intestinal mucin MUC2.

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Lindén SK, Bierne H, Sabet C, Png CW, Florin TH, McGuckin MA, and Cossart P

Archives of microbiology 190(1):101, 2008 Jul - Who cited this? | PubMed ID: 18327567 | Fulltext

Mucins in the mucosal barrier to infection.

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Linden SK, Sutton P, Karlsson NG, Korolik V, and McGuckin MA

Mucosal immunology 1(3):183-97, 2008 May - Who cited this? | PubMed ID: 19079178 | Fulltext

Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis.

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Heazlewood CK, Cook MC, Eri R, Price GR, Tauro SB, Taupin D, Thornton DJ, Png CW, Crockford TL, Cornall RJ, Adams R, Kato M, Nelms KA, Hong NA, Florin TH, Goodnow CC,

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PLoS medicine 5(3), 2008 Mar 4 - Who cited this? | PubMed ID: 18318598 | Fulltext

IgG antibodies against common gut bacteria are more diagnostic for Crohn's disease than IgG against mannan or flagellin.

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Adams RJ, Heazlewood SP, Gilshenan KS, O'Brien M, McGuckin MA, and Florin TH

The American journal of gastroenterology 103(2):386, 2008 Feb - Who cited this? | PubMed ID: 17924999 | Fulltext

Structure and function of the polymeric mucins in airways mucus.

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Thornton DJ, Rousseau K, and McGuckin MA

Annual review of physiology 70:459-86, 2008 - Who cited this? | PubMed ID: 17850213 | Fulltext

Mucin dynamics in intestinal bacterial infection.

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Lindén SK, Florin TH, and McGuckin MA

PLoS ONE 3(12):e3952, 2008 - Who cited this? | PubMed ID: 19088856 | Fulltext

Numerical and functional defects of blood dendritic cells in early- and late-stage breast cancer.

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Pinzon-Charry A, Ho CS, Maxwell T, McGuckin MA, Schmidt C, Furnival C, Pyke CM, and López JA

British journal of cancer 97(9):1251-9, 2007 Nov 5 - Who cited this? | PubMed ID: 17923873 | Fulltext

Muc1 mucin limits both Helicobacter pylori colonization of the murine gastric mucosa and associated gastritis.

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McGuckin MA, Every AL, Skene CD, Linden SK, Chionh YT, Swierczak A, McAuley J, Harbour S, Kaparakis M, Ferrero R, and Sutton P

Gastroenterology 133(4):1210-8, 2007 Oct - Who cited this? | PubMed ID: 17919495 | Fulltext

MUC1 cell surface mucin is a critical element of the mucosal barrier to infection.

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McAuley JL, Linden SK, Png CW, King RM, Pennington HL, Gendler SJ, Florin TH, Hill GR, Korolik V, and McGuckin MA

The Journal of clinical investigation 117(8):2313, 2007 Aug - Who cited this? | PubMed ID: 17641781 | Fulltext

Improved in vitro model systems for gastrointestinal infection by choice of cell line, pH, microaerobic conditions, and optimization of culture conditions.

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Lindén SK, Driessen KM, and McGuckin MA

Helicobacter 12(4):341-53, 2007 Aug - Who cited this? | PubMed ID: 17669108 | Fulltext

The MUC13 cell surface mucin is highly expressed by human colorectal carcinomas.

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Walsh MD, Young JP, Leggett BA, Williams SH, Jass JR, and McGuckin MA

Human pathology 38(6):883-92, 2007 Jun - Who cited this? | PubMed ID: 17360025 | Fulltext

Spontaneous apoptosis of blood dendritic cells in patients with breast cancer.

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Pinzon-Charry A, Maxwell T, McGuckin MA, Schmidt C, Furnival C, and López JA

Breast cancer research : BCR 8(1), 2006 - Who cited this? | PubMed ID: 16417648 | Fulltext

Expression of the cell surface mucin gene family in adenocarcinomas.

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Packer LM, Williams SJ, Callaghan S, Gotley DC, and McGuckin MA

International journal of oncology 25(4):1119-26, 2004 Oct - Who cited this? | PubMed ID: 15375564 | Fulltext

Suppressor of cytokine signalling gene expression is elevated in breast carcinoma.

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Raccurt M, Tam SP, Lau P, Mertani HC, Lambert A, Garcia-Caballero T, Li H, Brown RJ, McGuckin MA, Morel G, and Waters MJ

British journal of cancer 89(3):524-32, 2003 Aug 4 - Who cited this? | PubMed ID: 12888825 | Fulltext

Occult axillary lymph node metastases in breast cancer do matter: results of 10-year survival analysis.

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Cummings MC, Walsh MD, Hohn BG, Bennett IC, Wright RG, and McGuckin MA

The American journal of surgical pathology 26(10):1286-95, 2002 Oct - Who cited this? | PubMed ID: 12360043 | Fulltext

MUC1 epithelial mucin (CD227) is expressed by activated dendritic cells.

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Wykes M, MacDonald KP, Tran M, Quin RJ, Xing PX, Gendler SJ, Hart DN, and McGuckin MA

Journal of leukocyte biology 72(4):692-701, 2002 Oct - Who cited this? | PubMed ID: 12377938 | Fulltext

Expression of MUC1 splice variants in benign and malignant ovarian tumours.

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Obermair A, Schmid BC, Packer LM, Leodolter S, Birner P, Ward BG, Crandon AJ, McGuckin MA, and Zeillinger R

International journal of cancer. Journal international du cancer 100(2):166-71, 2002 Jul 10 - Who cited this? | PubMed ID: 12115565 | Fulltext

Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteins.

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Wreschner DH, McGuckin MA, Williams SJ, Baruch A, Yoeli M, Ziv R, Okun L, Zaretsky J, Smorodinsky N, Keydar I, Neophytou P, Stacey M, Lin HH, and Gordon S

Protein science : a publication of the Protein Society 11(3):698-706, 2002 Mar - Who cited this? | PubMed ID: 11847293 | Fulltext

Muc13, a novel human cell surface mucin expressed by epithelial and hemopoietic cells.

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Williams SJ, Wreschner DH, Tran M, Eyre HJ, Sutherland GR, and McGuckin MA

The Journal of biological chemistry 276(21):18327, 2001 May 25 - Who cited this? | PubMed ID: 11278439 | Fulltext

Transactivation-deficient p73alpha (p73Deltaexon2) inhibits apoptosis and competes with p53.

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Fillippovich I, Sorokina N, Gatei M, Haupt Y, Hobson K, Moallem E, Spring K, Mould M, McGuckin MA, Lavin MF, and Khanna KK

Oncogene 20(4):514-22, 2001 Jan 25 - Who cited this? | PubMed ID: 11313982 | Fulltext

MUC1: antibodies and immunoassays.

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Rye PD and McGuckin MA

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 22(4):269-72, 2001 - Who cited this? | PubMed ID: 11399953 | Fulltext

Phosphorylation of the cytoplasmic domain of the MUC1 mucin correlates with changes in cell-cell adhesion.

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Quin RJ and McGuckin MA

International journal of cancer. Journal international du cancer 87(4):499-506, 2000 Aug 15 - Who cited this? | PubMed ID: 10918188 | Fulltext

Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis.

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Biemer-Hüttmann AE, Walsh MD, McGuckin MA, Simms LA, Young J, Leggett BA, and Jass JR

Clinical cancer research : an official journal of the American Association for Cancer Research 6(5):1909-16, 2000 May - Who cited this? | PubMed ID: 10815915 | Fulltext

Detection and quantitation of mucins using chemical, lectin, and antibody methods.

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McGuckin MA and Thornton DJ

Methods in molecular biology (Clifton, N.J.) 125:45-55, 2000 - Who cited this? | PubMed ID: 10820748 | Fulltext

Heterogeneity of MUC1 expression by human breast carcinoma cell lines in vivo and in vitro.

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Walsh MD, Luckie SM, Cummings MC, Antalis TM, and McGuckin MA

Breast cancer research and treatment 58(3):255-66, 1999 Dec - Who cited this? | PubMed ID: 10718487 | Fulltext

Two novel mucin genes down-regulated in colorectal cancer identified by differential display.

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Williams SJ, McGuckin MA, Gotley DC, Eyre HJ, Sutherland GR, and Antalis TM

Cancer research 59(16):4083-9, 1999 Aug 15 - Who cited this? | PubMed ID: 10463611 | Fulltext

Immunohistochemical staining patterns of MUC1, MUC2, MUC4, and MUC5AC mucins in hyperplastic polyps, serrated adenomas, and traditional adenomas of the colorectum.

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Biemer-Hüttmann AE, Walsh MD, McGuckin MA, Ajioka Y, Watanabe H, Leggett BA, and Jass JR

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 47(8):1039-48, 1999 Aug - Who cited this? | PubMed ID: 10424888 | Fulltext

The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.

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Williams SJ, Munster DJ, Quin RJ, Gotley DC, and McGuckin MA

Biochemical and biophysical research communications 261(1):83-9, 1999 Jul 22 - Who cited this? | PubMed ID: 10405327 | Fulltext

Antibodies reactive with the protein core of MUC1 mucin are present in ovarian cancer patients and healthy women.

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Richards ER, Devine PL, Quin RJ, Fontenot JD, Ward BG, and McGuckin MA

Cancer immunology, immunotherapy : CII 46(5):245-52, 1998 Jul - Who cited this? | PubMed ID: 9690452 | Fulltext

Peritoneal fluid from ovarian cancer patients stimulates MUC1 epithelial mucin expression in ovarian cancer cell lines.

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Munster DJ, Quin RJ, Bansal AS, Ward BG, and McGuckin MA

International journal of cancer. Journal international du cancer 76(3):393-8, 1998 May 4 - Who cited this? | PubMed ID: 9579577 | Fulltext

Progesterone stimulates production and secretion of MUC1 epithelial mucin in steroid-responsive breast cancer cell lines.

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McGuckin MA, Quin RJ, and Ward BG

International journal of oncology 12(4):939-45, 1998 Apr - Who cited this? | PubMed ID: 9499459 | Fulltext

Expression of MUC1 and MUC2 mucins in epithelial ovarian tumours.

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Dong Y, Walsh MD, Cummings MC, Wright RG, Khoo SK, Parsons PG, and McGuckin MA

The Journal of pathology 183(3):311-7, 1997 Nov - Who cited this? | PubMed ID: 9422987 | Fulltext

Reduced expression of retinoblastoma gene product (pRB) and high expression of p53 are associated with poor prognosis in ovarian cancer.

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Dong Y, Walsh MD, McGuckin MA, Cummings MC, Gabrielli BG, Wright GR, Hurst T, Khoo SK, and Parsons PG

International journal of cancer. Journal international du cancer 74(4):407-15, 1997 Aug 22 - Who cited this? | PubMed ID: 9291430 | Fulltext

Increased expression of cyclin-dependent kinase inhibitor 2 (CDKN2A) gene product P16INK4A in ovarian cancer is associated with progression and unfavourable prognosis.

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Dong Y, Walsh MD, McGuckin MA, Gabrielli BG, Cummings MC, Wright RG, Hurst T, Khoo SK, and Parsons PG

International journal of cancer. Journal international du cancer 74(1):57-63, 1997 Feb 20 - Who cited this? | PubMed ID: 9036870 | Fulltext

Occult axillary node metastases in breast cancer: their detection and prognostic significance.

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McGuckin MA, Cummings MC, Walsh MD, Hohn BG, Bennett IC, and Wright RG

British journal of cancer 73(1):88-95, 1996 Jan - Who cited this? | PubMed ID: 8554990 | Fulltext

Early steps in the biosynthesis of MUC2 epithelial mucin in colon cancer cells.

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McGuckin MA, Devine PL, and Ward BG

Biochemistry and cell biology = Biochimie et biologie cellulaire 74(1):87-93, 1996 - Who cited this? | PubMed ID: 9035693 | Fulltext

Heterogeneity in production, secretion and glycosylation of MUC1 epithelial mucin by primary cultures of ovarian carcinoma.

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McGuckin MA, Hurst TG, and Ward BG

International journal of cancer. Journal international du cancer 63(3):412-8, 1995 Nov 3 - Who cited this? | PubMed ID: 7591241 | Fulltext

CA15-3, CASA, MSA, and TPS as diagnostic serum markers in breast cancer.

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Devine PL, Duroux MA, Quin RJ, McGuckin MA, Joy GJ, Ward BG, and Pollard CW

Breast cancer research and treatment 34(3):245-51, 1995 Jun - Who cited this? | PubMed ID: 7579489 | Fulltext

Prognostic significance of MUC1 epithelial mucin expression in breast cancer.

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McGuckin MA, Walsh MD, Hohn BG, Ward BG, and Wright RG

Human pathology 26(4):432-9, 1995 Apr - Who cited this? | PubMed ID: 7705823 | Fulltext

Prostate-specific antigen (PSA) and cancer-associated serum antigen (CASA) in distinguishing benign and malignant prostate disease.

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Devine PL, Walsh MD, McGuckin MA, Quin RJ, Hohn BG, Clague A, and Samaratunga H

The International journal of biological markers 10(4):221-5, 1995 - Who cited this? | PubMed ID: 8750649 | Fulltext

Effect of interferon-gamma and TNF-alpha on MUC1 mucin expression in ovarian carcinoma cell lines.

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Clark S, McGuckin MA, Hurst T, and Ward BG

Disease markers 12(1):43-50, 1994 Oct - Who cited this? | PubMed ID: 7842630 | Fulltext

Effect of interferon gamma and tumour necrosis factor alpha on sensitivity to cisplatin in ovarian carcinoma cell lines.

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Clark S, McGuckin MA, Hurst T, and Ward BG

Cancer immunology, immunotherapy : CII 39(2):100-4, 1994 Aug - Who cited this? | PubMed ID: 8044830 | Fulltext

Are CASA and CA125 concentrations in peripheral blood sourced from peritoneal fluid in women with pelvic masses?.

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Ward BG and McGuckin MA

Cancer 73(6):1699-703, 1994 Mar 15 - Who cited this? | PubMed ID: 8156497 | Fulltext

Mucin expression by transitional cell carcinomas of the bladder.

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Walsh MD, Hohn BG, Thong W, Devine PL, Gardiner RA, Samaratunga ML, and McGuckin MA

British journal of urology 73(3):256-62, 1994 Mar - Who cited this? | PubMed ID: 8162502 | Fulltext

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