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Papers authored by Marcinkeviciene J

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P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.

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Meredith JE, Thompson LA, Toyn JH, Marcin L, Barten DM, Marcinkeviciene J, Kopcho L, Kim Y, Lin A, Guss V, Burton C, Iben L, Polson C, Cantone J, Ford M, Drexler D,

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The Journal of pharmacology and experimental therapeutics 326(2):502, 2008 Aug - Who cited this? | PubMed ID: 18499745 | Fulltext

[(3)H]BMS-599240 - A novel tritiated ligand for the characterization of BACE1 inhibitors.

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Iben LG, Kopcho L, Marcinkeviciene J, Zheng C, Thompson LA, Albright CF, and Toyn JH

European journal of pharmacology, 2008 Jul 11 - Who cited this? | PubMed ID: 18655784 | Fulltext

Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate.

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Locke GA, Cheng D, Witmer MR, Tamura JK, Haque T, Carney RF, Rendina AR, and Marcinkeviciene J

Archives of biochemistry and biophysics 475(1):72-9, 2008 Jul 1 - Who cited this? | PubMed ID: 18455495 | Fulltext

Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation.

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Metzler WJ, Yanchunas J, Weigelt C, Kish K, Klei HE, Xie D, Zhang Y, Corbett M, Tamura JK, He B, Hamann LG, Kirby MS, and Marcinkeviciene J

Protein science : a publication of the Protein Society 17(2):240-50, 2008 Feb - Who cited this? | PubMed ID: 18227430 | Fulltext

[Evaluation of a chronic fatigue in patients with moderate-to-severe chronic heart failure].

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Jasiukeviciene L, Vasiliauskas D, Kavoliūniene A, Marcinkeviciene J, Grybauskiene R, Grizas V, and Tumyniene V

Medicina (Kaunas, Lithuania) 44(5):366, 2008 - Who cited this? | PubMed ID: 18541952 | Fulltext

[Return to work after coronary artery bypass surgery].

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Vasiliauskas D, Raugaliene R, Grizas V, Marcinkeviciene J, Jasiukeviciene L, Kubilius R, and Barsys V

Medicina (Kaunas, Lithuania) 44(11):841-7, 2008 - Who cited this? | PubMed ID: 19124960 | Fulltext

Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors.

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Simpkins LM, Bolton S, Pi Z, Sutton JC, Kwon C, Zhao G, Magnin DR, Augeri DJ, Gungor T, Rotella DP, Sun Z, Liu Y, Slusarchyk WS, Marcinkeviciene J, Robertson JG, Wang A,

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Bioorganic & medicinal chemistry letters 17(23):6476-80, 2007 Dec 1 - Who cited this? | PubMed ID: 17937986 | Fulltext

Exercise training after coronary angioplasty improves cardiorespiratory function.

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Vasiliauskas D, Benetis R, Jasiukeviciene L, Grizas V, Marcinkeviciene J, Navickas R, and Leimoniene L

Scandinavian cardiovascular journal : SCJ 41(3):142-8, 2007 Jun - Who cited this? | PubMed ID: 17487762 | Fulltext

A pre-steady state analysis of ligand binding to human glucokinase: evidence for a preexisting equilibrium.

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Kim YB, Kalinowski SS, and Marcinkeviciene J

Biochemistry 46(5):1423-31, 2007 Feb 6 - Who cited this? | PubMed ID: 17260972 | Fulltext

Development of structural cardiac adaptation in basketball players.

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Vasiliauskas D, Venckūnas T, Marcinkeviciene J, and Bartkeviciene A

European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 13(6):985-9, 2006 Dec - Who cited this? | PubMed ID: 17143132 | Fulltext

Seco-prolinenitrile inhibitors of dipeptidyl peptidase IV define minimal pharmacophore requirements at P1.

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Magnin DR, Taunk PC, Robertson JG, Wang A, Marcinkeviciene J, Kirby MS, and Hamann LG

Bioorganic & medicinal chemistry letters 16(6):1731-4, 2006 Mar 15 - Who cited this? | PubMed ID: 16376077 | Fulltext

Mechanism of Gly-Pro-pNA cleavage catalyzed by dipeptidyl peptidase-IV and its inhibition by saxagliptin (BMS-477118).

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Kim YB, Kopcho LM, Kirby MS, Hamann LG, Weigelt CA, Metzler WJ, and Marcinkeviciene J

Archives of biochemistry and biophysics 445(1):9-18, 2006 Jan 1 - Who cited this? | PubMed ID: 16364232 | Fulltext

[Left ventricular remodeling in ischemic heart disease patients with signs and symptoms of chronic heart failure: an impact of the long-term exercise training].

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Vasiliauskas D, Kavoliūniene A, Jasiukeviciene L, Grizas V, Marcinkeviciene J, Raugaliene R, Leimoniene L, and Tumyniene V

Medicina (Kaunas, Lithuania) 42(12):965-74, 2006 - Who cited this? | PubMed ID: 17211104 | Fulltext

Diprolyl nitriles as potent dipeptidyl peptidase IV inhibitors.

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Zhao G, Taunk PC, Magnin DR, Simpkins LM, Robl JA, Wang A, Robertson JG, Marcinkeviciene J, Sitkoff DF, Parker RA, Kirby MS, and Hamann LG

Bioorganic & medicinal chemistry letters 15(18):3992-5, 2005 Sep 15 - Who cited this? | PubMed ID: 16046120 | Fulltext

Discovery and preclinical profile of Saxagliptin (BMS-477118): a highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

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Augeri DJ, Robl JA, Betebenner DA, Magnin DR, Khanna A, Robertson JG, Wang A, Simpkins LM, Taunk P, Huang Q, Han SP, Abboa-Offei B, Cap M, Xin L, Tao L, Tozzo E,

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Journal of medicinal chemistry 48(15):5025-37, 2005 Jul 28 - Who cited this? | PubMed ID: 16033281 | Fulltext

Probing prime substrate binding sites of human dipeptidyl peptidase-IV using competitive substrate approach.

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Kopcho LM, Kim YB, Wang A, Liu MA, Kirby MS, and Marcinkeviciene J

Archives of biochemistry and biophysics 436(2):367-76, 2005 Apr 15 - Who cited this? | PubMed ID: 15797249 | Fulltext

[Relationship between the metabolic syndrome, endothelial function and intima-media thickness in asymptomatic middle-aged individuals].

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Gustiene O, Slapikas R, Marcinkeviciene J, Petrauskiene I, Milasauskiene Z, Griskeviciūte R, Plepyte J, and Zaliūnas R

Medicina (Kaunas, Lithuania) 41(10):825-36, 2005 - Who cited this? | PubMed ID: 16272829 | Fulltext

Comparative studies of active site-ligand interactions among various recombinant constructs of human beta-amyloid precursor protein cleaving enzyme.

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Kopcho LM, Ma J, Marcinkeviciene J, Lai Z, Witmer MR, Cheng J, Yanchunas J, Tredup J, Corbett M, Calambur D, Wittekind M, Paruchuri M, Kothari D, Lee G, Ganguly S, Ramamurthy V,

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Archives of biochemistry and biophysics 410(2):307-16, 2003 Feb 15 - Who cited this? | PubMed ID: 12573291 | Fulltext

Kinetic studies on beta-site amyloid precursor protein-cleaving enzyme (BACE). Confirmation of an iso mechanism.

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Toulokhonova L, Metzler WJ, Witmer MR, Copeland RA, and Marcinkeviciene J

The Journal of biological chemistry 278(7):4582-9, 2003 Feb 14 - Who cited this? | PubMed ID: 12458195 | Fulltext

Parallel synthesis of potent, pyrazole-based inhibitors of Helicobacter pylori dihydroorotate dehydrogenase.

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Haque TS, Tadesse S, Marcinkeviciene J, Rogers MJ, Sizemore C, Kopcho LM, Amsler K, Ecret LD, Zhan DL, Hobbs F, Slee A, Trainor GL, Stern AM, Copeland RA, and Combs AP

Journal of medicinal chemistry 45(21):4669-78, 2002 Oct 10 - Who cited this? | PubMed ID: 12361393 | Fulltext

Novel inhibition of porcine pepsin by a substituted piperidine. Preference for one of the enzyme conformers.

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Marcinkeviciene J, Kopcho LM, Yang T, Copeland RA, Glass BM, Combs AP, Falahatpisheh N, and Thompson L

The Journal of biological chemistry 277(32):28677-82, 2002 Aug 9 - Who cited this? | PubMed ID: 12029090 | Fulltext

Mechanism of Inhibition of beta-site amyloid precursor protein-cleaving enzyme (BACE) by a statine-based peptide.

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Marcinkeviciene J, Luo Y, Graciani NR, Combs AP, and Copeland RA

The Journal of biological chemistry 276(26):23790-4, 2001 Jun 29 - Who cited this? | PubMed ID: 11306583 | Fulltext

Enoyl-ACP reductase (FabI) of Haemophilus influenzae: steady-state kinetic mechanism and inhibition by triclosan and hexachlorophene.

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Marcinkeviciene J, Jiang W, Kopcho LM, Locke G, Luo Y, and Copeland RA

Archives of biochemistry and biophysics 390(1):101-8, 2001 Jun 1 - Who cited this? | PubMed ID: 11368521 | Fulltext

Characterization of recombinant, soluble beta-secretase from an insect cell expression system.

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Mallender WD, Yager D, Onstead L, Nichols MR, Eckman C, Sambamurti K, Kopcho LM, Marcinkeviciene J, Copeland RA, and Rosenberry TL

Molecular pharmacology 59(3):619-26, 2001 Mar - Who cited this? | PubMed ID: 11179458 | Fulltext

Helicobacter pylori-selective antibacterials based on inhibition of pyrimidine biosynthesis.

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Copeland RA, Marcinkeviciene J, Haque TS, Kopcho LM, Jiang W, Wang K, Ecret LD, Sizemore C, Amsler KA, Foster L, Tadesse S, Combs AP, Stern AM, Trainor GL, Slee A, Rogers MJ,

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The Journal of biological chemistry 275(43):33373, 2000 Oct 27 - Who cited this? | PubMed ID: 10938275 | Fulltext

Selective inhibition of bacterial dihydroorotate dehydrogenases by thiadiazolidinediones.

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Marcinkeviciene J, Rogers MJ, Kopcho L, Jiang W, Wang K, Murphy DJ, Lippy J, Link S, Chung TD, Hobbs F, Haque T, Trainor GL, Slee A, Stern AM, and Copeland RA

Biochemical pharmacology 60(3):339-42, 2000 Aug 1 - Who cited this? | PubMed ID: 10856428 | Fulltext

Role of lys100 in human dihydroorotate dehydrogenase: mutagenesis studies and chemical rescue by external amines.

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Jiang W, Locke G, Harpel MR, Copeland RA, and Marcinkeviciene J

Biochemistry 39(27):7990-7, 2000 Jul 11 - Who cited this? | PubMed ID: 10891080 | Fulltext

A second dihydroorotate dehydrogenase (Type A) of the human pathogen Enterococcus faecalis: expression, purification, and steady-state kinetic mechanism.

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Marcinkeviciene J, Jiang W, Locke G, Kopcho LM, Rogers MJ, and Copeland RA

Archives of biochemistry and biophysics 377(1):178-86, 2000 May 1 - Who cited this? | PubMed ID: 10775458 | Fulltext

Dihydroorotate dehydrogenase B of Enterococcus faecalis. Characterization and insights into chemical mechanism.

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Marcinkeviciene J, Tinney LM, Wang KH, Rogers MJ, and Copeland RA

Biochemistry 38(40):13129-37, 1999 Oct 5 - Who cited this? | PubMed ID: 10529184 | Fulltext

Thioredoxin reductase-thioredoxin fusion enzyme from Mycobacterium leprae: comparison with the separately expressed thioredoxin reductase.

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Wang PF, Marcinkeviciene J, Williams CH, and Blanchard JS

Biochemistry 37(46):16378-89, 1998 Nov 17 - Who cited this? | PubMed ID: 9819230 | Fulltext

Antisense RNA to ahpC, an oxidative stress defence gene involved in isoniazid resistance, indicates that AhpC of Mycobacterium bovis has virulence properties.

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Wilson T, De Lisle GW, Marcinkeviciene JA, Blanchard JS, and Collins DM

Microbiology (Reading, England) 144 ( Pt 10):2687, 1998 Oct - Who cited this? | PubMed ID: 9802010 | Fulltext

Enterococcus faecalis glutathione reductase: purification, characterization and expression under normal and hyperbaric O2 conditions.

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Patel MP, Marcinkeviciene J, and Blanchard JS

FEMS microbiology letters 166(1):155-63, 1998 Sep 1 - Who cited this? | PubMed ID: 9741094 | Fulltext

NADH dehydrogenase defects confer isoniazid resistance and conditional lethality in Mycobacterium smegmatis.

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Miesel L, Weisbrod TR, Marcinkeviciene JA, Bittman R, and Jacobs WR

Journal of bacteriology 180(9):2459-67, 1998 May - Who cited this? | PubMed ID: 9573199 | Fulltext

Catalytic properties of lipoamide dehydrogenase from Mycobacterium smegmatis.

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Marcinkeviciene J and Blanchard JS

Archives of biochemistry and biophysics 340(2):168-76, 1997 Apr 15 - Who cited this? | PubMed ID: 9143318 | Fulltext

The role of Mn(II)-peroxidase activity of mycobacterial catalase-peroxidase in activation of the antibiotic isoniazid.

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Magliozzo RS and Marcinkeviciene JA

The Journal of biological chemistry 272(14):8867-70, 1997 Apr 4 - Who cited this? | PubMed ID: 9083004 | Fulltext

Electrostimulated cardiomyoplasty: from experimental to clinical studies.

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Dumcius A, Salcius K, Raliene L, Vaskelyte J, Giedraitis S, Sirvinskas E, Marcinkeviciene J, and Skucas J

Pacing and clinical electrophysiology : PACE 19(8):1205-10, 1996 Aug - Who cited this? | PubMed ID: 8865218 | Fulltext

Purification and characterization of the Mycobacterium smegmatis catalase-peroxidase involved in isoniazid activation.

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Marcinkeviciene JA, Magliozzo RS, and Blanchard JS

The Journal of biological chemistry 270(38):22290-5, 1995 Sep 22 - Who cited this? | PubMed ID: 7673210 | Fulltext

Quinone reductase reaction catalyzed by Streptococcus faecalis NADH peroxidase.

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Marcinkeviciene JA and Blanchard JS

Biochemistry 34(20):6621-7, 1995 May 23 - Who cited this? | PubMed ID: 7756294 | Fulltext

Kinetics of glucose oxidase catalyzed electron transfer mediated by sulfur and selenium compounds.

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Kulys J, Buch-Rasmussen T, Bechgaard K, Marcinkeviciene J, Christensen JB, and Hansen HE

FEBS letters 329(1-2):205-9, 1993 Aug 23 - Who cited this? | PubMed ID: 8354396 | Fulltext

Kinetic studies of the active sites functioning in the quinohemoprotein fructose dehydrogenase.

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Marcinkeviciene J and Johansson G

FEBS letters 318(1):23-6, 1993 Feb 22 - Who cited this? | PubMed ID: 8436220 | Fulltext

Bienzyme strip-type glucose sensor.

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Marcinkeviciene J and Kulys J

Biosensors & bioelectronics 8(3-4):209-12, 1993 - Who cited this? | PubMed ID: 8357575 | Fulltext

A negative cooperativity between NADPH and adrenodoxin on binding to NADPH:adrenodoxin reductase.

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Cénas NK, Marcinkeviciene JA, Kulys JJ, and Usanov SA

FEBS letters 259(2):338-40, 1990 Jan 1 - Who cited this? | PubMed ID: 2294024 | Fulltext

Nitroreductase reactions of the NADPH: adrenodoxin reductase and the adrenodoxin complex.

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Marcinkeviciene J, Cenas N, Kulys J, Usanov SA, Sukhova NM, Selezneva IS, and Gryazev VF

Biomedica biochimica acta 49(4):167-72, 1990 - Who cited this? | PubMed ID: 2403337 | Fulltext

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