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Papers authored by Maldarelli F

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Short-Course Raltegravir Intensification Does Not Reduce Persistent Low-Level Viremia in Patients with HIV-1 Suppression during Receipt of Combination Antiretroviral Therapy.

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McMahon D, Jones J, Wiegand A, Gange SJ, Kearney M, Palmer S, McNulty S, Metcalf JA, Acosta E, Rehm C, Coffin JM, Mellors JW, and Maldarelli F

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 50(6):912-9, 2010 Mar 15 - Who cited this? | PubMed ID: 20156060 | Fulltext

Subtype-Specific Differences in the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Connection Subdomain of CRF01_AE Are Associated with Higher Levels of Resistance to 3'-Azido-3'-Deoxythymidine.

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Delviks-Frankenberry KA, Nikolenko GN, Maldarelli F, Hase S, Takebe Y, and Pathak VK

Journal of virology 83(17):8502-13, 2009 Sep - Who cited this? | PubMed ID: 19553318 | Fulltext

Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy.

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Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, O'Shea A, Callender M, Spivak A, Brennan T, Kearney MF, Proschan MA, Mican JM, Rehm CA, Coffin JM, Mellors JW,

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Proceedings of the National Academy of Sciences of the United States of America 106(23):9403-8, 2009 Jun 9 - Who cited this? | PubMed ID: 19470482 | Fulltext

Evaluation of the pathogenesis of decreasing CD4(+) T cell counts in human immunodeficiency virus type 1-infected patients receiving successfully suppressive antiretroviral therapy.

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Nies-Kraske E, Schacker TW, Condoluci D, Orenstein J, Brenchley J, Fox C, Daucher M, Dewar R, Urban E, Hill B, Guenaga J, Hoover S, Maldarelli F, Hallahan CW, Horn J, Kottilil S,

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The Journal of infectious diseases 199(11):1648-56, 2009 Jun 1 - Who cited this? | PubMed ID: 19432547 | Fulltext

Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy: final 48-week clinical and virologic outcomes.

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Wilkin TJ, McKinnon JE, DiRienzo AG, Mollan K, Fletcher CV, Margolis DM, Bastow B, Thal G, Woodward W, Godfrey C, Wiegand A, Maldarelli F, Palmer S, Coffin JM, Mellors JW, and Swindells S

The Journal of infectious diseases 199(6):866-71, 2009 Mar 15 - Who cited this? | PubMed ID: 19191590 | Fulltext

Human immunodeficiency virus type 1 population genetics and adaptation in newly infected individuals.

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Kearney M, Maldarelli F, Shao W, Margolick JB, Daar ES, Mellors JW, Rao V, Coffin JM, and Palmer S

Journal of virology 83(6):2715-27, 2009 Mar - Who cited this? | PubMed ID: 19116249 | Fulltext

Inferiority of IL-2 alone versus IL-2 with HAART in maintaining CD4 T cell counts during HAART interruption: a randomized controlled trial.

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Porter BO, Anthony KB, Shen J, Hahn B, Keh CE, Maldarelli F, Blackwelder WC, Lane HC, Kovacs JA, Davey RT, and Sereti I

AIDS (London, England) 23(2):203-12, 2009 Jan 14 - Who cited this? | PubMed ID: 19098490 | Fulltext

RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy.

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Shao W, Kearney M, Maldarelli F, Mellors JW, Stephens RM, Lifson JD, KewalRamani VN, Ambrose Z, Coffin JM, and Palmer SE

Retrovirology 6:101, 2009 - Who cited this? | PubMed ID: 19889213 | Fulltext

Iatrogenic Cushing syndrome after epidural triamcinolone injections in an HIV type 1-infected patient receiving therapy with ritonavir-lopinavir.

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Ramanathan R, Pau AK, Busse KH, Zemskova M, Nieman L, Kwan R, Hammer JH, Mican JM, and Maldarelli F

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 47(12):e97-9, 2008 Dec 15 - Who cited this? | PubMed ID: 18991509 | Fulltext

Lytic Granule Loading of CD8(+) T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control.

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Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, Weeks KA, Rood JE, Berkley AM, Sacha JB, Cogliano-Shutta NA, Lloyd M, Roby G, Kwan R, McLaughlin M, Stallings S, Rehm C,

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Immunity 29(6):1009-21, 2008 Dec - Who cited this? | PubMed ID: 19062316 | Fulltext

Efavirenz Induces CYP2B6-Mediated Hydroxylation of Bupropion in Healthy Subjects.

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Robertson SM, Maldarelli F, Natarajan V, Formentini E, Alfaro RM, and Penzak SR

Journal of acquired immune deficiency syndromes (1999), 2008 Nov 4 - Who cited this? | PubMed ID: 18989234 | Fulltext

Variation in the Major Surface Glycoprotein Genes in Pneumocystis jirovecii.

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Kutty G, Maldarelli F, Achaz G, and Kovacs JA

The Journal of infectious diseases 198(5):741, 2008 Sep 1 - Who cited this? | PubMed ID: 18627244 | Fulltext

Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy.

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Palmer S, Maldarelli F, Wiegand A, Bernstein B, Hanna GJ, Brun SC, Kempf DJ, Mellors JW, Coffin JM, and King MS

Proceedings of the National Academy of Sciences of the United States of America 105(10):3879, 2008 Mar 11 - Who cited this? | PubMed ID: 18332425 | Fulltext

Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase.

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Kearney M, Palmer S, Maldarelli F, Shao W, Polis MA, Mican J, Rock-Kress D, Margolick JB, Coffin JM, and Mellors JW

AIDS (London, England) 22(4):497-501, 2008 Feb 19 - Who cited this? | PubMed ID: 18301062 | Fulltext

Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy.

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Ambrose Z, Palmer S, Boltz VF, Kearney M, Larsen K, Polacino P, Flanary L, Oswald K, Piatak M, Smedley J, Shao W, Bischofberger N, Maldarelli F, Kimata JT, Mellors JW, Hu SL,

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Journal of virology 81(22):12145-55, 2007 Nov - Who cited this? | PubMed ID: 17855539 | Fulltext

ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia.

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Maldarelli F, Palmer S, King MS, Wiegand A, Polis MA, Mican J, Kovacs JA, Davey RT, Rock-Kress D, Dewar R, Liu S, Metcalf JA, Rehm C, Brun SC, Hanna GJ, Kempf DJ,

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PLoS pathogens 3(4):e46, 2007 Apr - Who cited this? | PubMed ID: 17411338 | Fulltext

Enfuvirtide antiviral activity despite rebound viremia and resistance mutations: fitness tampering or a case of persistent braking on entering?.

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Morse C and Maldarelli F

The Journal of infectious diseases 195(3):318-21, 2007 Feb 1 - Who cited this? | PubMed ID: 17205468 | Fulltext

Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance.

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Nikolenko GN, Delviks-Frankenberry KA, Palmer S, Maldarelli F, Fivash MJ, Coffin JM, and Pathak VK

Proceedings of the National Academy of Sciences of the United States of America 104(1):317-22, 2007 Jan 2 - Who cited this? | PubMed ID: 17179211 | Fulltext

Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy: impact on bone mineral density in HIV-infected children.

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Gafni RI, Hazra R, Reynolds JC, Maldarelli F, Tullio AN, DeCarlo E, Worrell CJ, Flaherty JF, Yale K, Kearney BP, and Zeichner SL

Pediatrics 118(3), 2006 Sep - Who cited this? | PubMed ID: 16923923 | Fulltext

Consistent effects of TSG101 genetic variability on multiple outcomes of exposure to human immunodeficiency virus type 1.

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Bashirova AA, Bleiber G, Qi Y, Hutcheson H, Yamashita T, Johnson RC, Cheng J, Alter G, Goedert JJ, Buchbinder S, Hoots K, Vlahov D, May M, Maldarelli F, Jacobson L, O'brien SJ,

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Journal of virology 80(14):6757-63, 2006 Jul - Who cited this? | PubMed ID: 16809281 | Fulltext

Persistence of nevirapine-resistant HIV-1 in women after single-dose nevirapine therapy for prevention of maternal-to-fetal HIV-1 transmission.

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Palmer S, Boltz V, Martinson N, Maldarelli F, Gray G, McIntyre J, Mellors J, Morris L, and Coffin J

Proceedings of the National Academy of Sciences of the United States of America 103(18):7094-9, 2006 May 2 - Who cited this? | PubMed ID: 16641095 | Fulltext

Selection and persistence of non-nucleoside reverse transcriptase inhibitor-resistant HIV-1 in patients starting and stopping non-nucleoside therapy.

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Palmer S, Boltz V, Maldarelli F, Kearney M, Halvas EK, Rock D, Falloon J, Davey RT, Dewar RL, Metcalf JA, Mellors JW, and Coffin JM

AIDS (London, England) 20(5):701-10, 2006 Mar 21 - Who cited this? | PubMed ID: 16514300 | Fulltext

Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy for pediatric HIV infection.

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Hazra R, Gafni RI, Maldarelli F, Balis FM, Tullio AN, DeCarlo E, Worrell CJ, Steinberg SM, Flaherty J, Yale K, Kearney BP, and Zeichner SL

Pediatrics 116(6):e846-54, 2005 Dec - Who cited this? | PubMed ID: 16291735 | Fulltext

Pravastatin does not have a consistent antiviral effect in chronically HIV-infected individuals on antiretroviral therapy.

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Sklar PA, Masur H, Grubb JR, Voell J, Witek J, Ono A, Freed EO, and Maldarelli F

AIDS (London, England) 19(10):1109-11, 2005 Jul 1 - Who cited this? | PubMed ID: 15958846 | Fulltext

Mechanisms of nonrandom human immunodeficiency virus type 1 infection and double infection: preference in virus entry is important but is not the sole factor.

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Chen J, Dang Q, Unutmaz D, Pathak VK, Maldarelli F, Powell D, and Hu WS

Journal of virology 79(7):4140-9, 2005 Apr - Who cited this? | PubMed ID: 15767415 | Fulltext

Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision.

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Nikolenko GN, Palmer S, Maldarelli F, Mellors JW, Coffin JM, and Pathak VK

Proceedings of the National Academy of Sciences of the United States of America 102(6):2093-8, 2005 Feb 8 - Who cited this? | PubMed ID: 15684061 | Fulltext

Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis.

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Palmer S, Kearney M, Maldarelli F, Halvas EK, Bixby CJ, Bazmi H, Rock D, Falloon J, Davey RT, Dewar RL, Metcalf JA, Hammer S, Mellors JW, and Coffin JM

Journal of clinical microbiology 43(1):406-13, 2005 Jan - Who cited this? | PubMed ID: 15635002 | Fulltext

A robust measure of HIV-1 population turnover within chronically infected individuals.

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Achaz G, Palmer S, Kearney M, Maldarelli F, Mellors JW, Coffin JM, and Wakeley J

Molecular biology and evolution 21(10):1902, 2004 Oct - Who cited this? | PubMed ID: 15215321 | Fulltext

A proof-of-concept study of short-cycle intermittent antiretroviral therapy with a once-daily regimen of didanosine, lamivudine, and efavirenz for the treatment of chronic HIV infection.

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Dybul M, Nies-Kraske E, Dewar R, Maldarelli F, Hallahan CW, Daucher M, Piscitelli SC, Ehler L, Weigand A, Palmer S, Metcalf JA, Davey RT, Rock Kress DM, Powers A, Beck I, Frenkel L,

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The Journal of infectious diseases 189(11):1974-82, 2004 Jun 1 - Who cited this? | PubMed ID: 15143462 | Fulltext

Nonrandom HIV-1 infection and double infection via direct and cell-mediated pathways.

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Dang Q, Chen J, Unutmaz D, Coffin JM, Pathak VK, Powell D, KewalRamani VN, Maldarelli F, and Hu WS

Proceedings of the National Academy of Sciences of the United States of America 101(2):632-7, 2004 Jan 13 - Who cited this? | PubMed ID: 14707263 | Fulltext

Changes in hepatitis C viral response after initiation of highly active antiretroviral therapy and control of HIV viremia in chronically co-infected individuals.

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Kottilil S, Jagannatha S, Lu A, Liu S, McLaughlin M, Metcalf JA, Dewar R, Campbell C, Koratich C, Maldarelli F, Masur H, and Polis MA

HIV clinical trials 5(1):25-32, 2004 - Who cited this? | PubMed ID: 15002084 | Fulltext

New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma.

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Palmer S, Wiegand AP, Maldarelli F, Bazmi H, Mican JM, Polis M, Dewar RL, Planta A, Liu S, Metcalf JA, Mellors JW, and Coffin JM

Journal of clinical microbiology 41(10):4531-6, 2003 Oct - Who cited this? | PubMed ID: 14532178 | Fulltext

Innate immunity in human immunodeficiency virus infection: effect of viremia on natural killer cell function.

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Kottilil S, Chun TW, Moir S, Liu S, McLaughlin M, Hallahan CW, Maldarelli F, Corey L, and Fauci AS

The Journal of infectious diseases 187(7):1038-45, 2003 Apr 1 - Who cited this? | PubMed ID: 12660917 | Fulltext

Effect of rev on the cytoplasmic localization of intron-containing human immunodeficiency virus type 1 RNA.

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Favaro JP, Maldarelli F, Arrigo SJ, and Schmidt MG

Virology 255(2):237-49, 1999 Mar 15 - Who cited this? | PubMed ID: 10069949 | Fulltext

Human T-cell leukemia virus type 1 Tax and cell cycle progression: role of cyclin D-cdk and p110Rb.

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Neuveut C, Low KG, Maldarelli F, Schmitt I, Majone F, Grassmann R, and Jeang KT

Molecular and cellular biology 18(6):3620-32, 1998 Jun - Who cited this? | PubMed ID: 9584203 | Fulltext

The expression of the essential nuclear splicing factor SC35 is altered by human immunodeficiency virus infection.

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Maldarelli F, Xiang C, Chamoun G, and Zeichner SL

Virus research 53(1):39-51, 1998 Jan - Who cited this? | PubMed ID: 9617768 | Fulltext

Efficient expression by an alphavirus replicon of a functional ribozyme targeted to human immunodeficiency virus type 1.

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Smith SM, Maldarelli F, and Jeang KT

Journal of virology 71(12):9713-21, 1997 Dec - Who cited this? | PubMed ID: 9371637 | Fulltext

Selenium supplementation suppresses tumor necrosis factor alpha-induced human immunodeficiency virus type 1 replication in vitro.

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Hori K, Hatfield D, Maldarelli F, Lee BJ, and Clouse KA

AIDS research and human retroviruses 13(15):1325-32, 1997 Oct 10 - Who cited this? | PubMed ID: 9339849 | Fulltext

Infection and pathogenicity of chimeric simian-human immunodeficiency viruses in macaques: determinants of high virus loads and CD4 cell killing.

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Shibata R, Maldarelli F, Siemon C, Matano T, Parta M, Miller G, Fredrickson T, and Martin MA

The Journal of infectious diseases 176(2):362-73, 1997 Aug - Who cited this? | PubMed ID: 9237701 | Fulltext

Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infection.

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Freed EO, Englund G, Maldarelli F, and Martin MA

Cell 88(2):171-3; discussion 173-4, 1997 Jan 24 - Who cited this? | PubMed ID: 9008157 | Fulltext

Human immunodeficiency virus type 1 infection of H9 cells induces increased glucose transporter expression.

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Sorbara LR, Maldarelli F, Chamoun G, Schilling B, Chokekijcahi S, Staudt L, Mitsuya H, Simpson IA, and Zeichner SL

Journal of virology 70(10):7275-9, 1996 Oct - Who cited this? | PubMed ID: 8794382 | Fulltext

Bimodal down-regulation of CD4 in cells expressing human immunodeficiency virus type 1 Vpu and Env.

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Fujita K, Maldarelli F, and Silver J

The Journal of general virology 77 ( Pt 10):2393-401, 1996 Oct - Who cited this? | PubMed ID: 8887470 | Fulltext

cis-acting elements in human immunodeficiency virus type 1 RNAs direct viral transcripts to distinct intranuclear locations.

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Berthold E and Maldarelli F

Journal of virology 70(7):4667-82, 1996 Jul - Who cited this? | PubMed ID: 8676493 | Fulltext

Rapid induction of apoptosis by cell-to-cell transmission of human immunodeficiency virus type 1.

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Maldarelli F, Sato H, Berthold E, Orenstein J, and Martin MA

Journal of virology 69(10):6457-65, 1995 Oct - Who cited this? | PubMed ID: 7666547 | Fulltext

Murine retroviral vector that induces long-term expression of HIV-1 envelope protein.

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Fujita K, Maldarelli F, Purcell DF, and Silver J

Journal of virological methods 50(1-3):293-311, 1994 Dec - Who cited this? | PubMed ID: 7714053 | Fulltext

Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein.

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Maldarelli F, Chen MY, Willey RL, and Strebel K

Journal of virology 67(8):5056-61, 1993 Aug - Who cited this? | PubMed ID: 8331740 | Fulltext

Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity.

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Chen MY, Maldarelli F, Karczewski MK, Willey RL, and Strebel K

Journal of virology 67(7):3877-84, 1993 Jul - Who cited this? | PubMed ID: 8510209 | Fulltext

Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4.

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Willey RL, Maldarelli F, Martin MA, and Strebel K

Journal of virology 66(12):7193-200, 1992 Dec - Who cited this? | PubMed ID: 1433512 | Fulltext

Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes.

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Willey RL, Maldarelli F, Martin MA, and Strebel K

Journal of virology 66(1):226-34, 1992 Jan - Who cited this? | PubMed ID: 1727486 | Fulltext

Identification of posttranscriptionally active inhibitory sequences in human immunodeficiency virus type 1 RNA: novel level of gene regulation.

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Maldarelli F, Martin MA, and Strebel K

Journal of virology 65(11):5732-43, 1991 Nov - Who cited this? | PubMed ID: 1656066 | Fulltext

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