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Papers authored by Mackay CR

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The functional plasticity of T cell subsets.

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Bluestone JA, Mackay CR, O'Shea JJ, and Stockinger B

Nature reviews. Immunology 9(11):811-6, 2009 Nov - Who cited this? | PubMed ID: 19809471 | Fulltext

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.

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Maslowski KM, Vieira AT, Ng A, Kranich J, Sierro F, Yu D, Schilter HC, Rolph MS, Mackay F, Artis D, Xavier RJ, Teixeira MM, and Mackay CR

Nature 461(7268):1282-6, 2009 Oct 29 - Who cited this? | PubMed ID: 19865172 | Fulltext

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

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Yu D, Rao S, Tsai LM, Lee SK, He Y, Sutcliffe EL, Srivastava M, Linterman M, Zheng L, Simpson N, Ellyard JI, Parish IA, Ma CS, Li QJ, Parish CR, Mackay CR,

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Immunity 31(3):457-68, 2009 Sep 18 - Who cited this? | PubMed ID: 19631565 | Fulltext

Ethical considerations of live case transmissions.

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Mackay CR

JACC. Cardiovascular interventions 2(9):892-3, 2009 Sep - Who cited this? | PubMed ID: 19778780 | Fulltext

Guidance of B cells by the orphan G protein-coupled receptor EBI2 shapes humoral immune responses.

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Gatto D, Paus D, Basten A, Mackay CR, and Brink R

Immunity 31(2):259-69, 2009 Aug 21 - Who cited this? | PubMed ID: 19615922 | Fulltext

Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia.

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Agrawal L, Maxwell CR, Peters PJ, Clapham PR, Liu SM, Mackay CR, and Strayer DS

The Journal of general virology 90(Pt 3):710-22, 2009 Mar - Who cited this? | PubMed ID: 19218218 | Fulltext

Moving targets: cell migration inhibitors as new anti-inflammatory therapies.

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Mackay CR

Nature immunology 9(9):988, 2008 Sep - Who cited this? | PubMed ID: 18711436 | Fulltext

Polymorphism in the 5' regulatory region of the B-lymphocyte activating factor gene is associated with the Ro/La autoantibody response and serum BAFF levels in primary Sjogren's syndrome.

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Nossent JC, Lester S, Zahra D, Mackay CR, and Rischmueller M

Rheumatology (Oxford, England), 2008 Jul 10 - Who cited this? | PubMed ID: 18617551 | Fulltext

A fundamental role for interleukin-21 in the generation of T follicular helper cells.

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Vogelzang A, McGuire HM, Yu D, Sprent J, Mackay CR, and King C

Immunity 29(1):127, 2008 Jul - Who cited this? | PubMed ID: 18602282 | Fulltext

Functional roles for C5a receptors in sepsis.

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Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Köhl J, Gerard C, Sarma JV, and Ward PA

Nature medicine 14(5):551, 2008 May - Who cited this? | PubMed ID: 18454156 | Fulltext

Granulocyte-macrophage colony-stimulating factor is required for bronchial eosinophilia in a murine model of allergic airway inflammation.

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Su YC, Rolph MS, Hansbro NG, Mackay CR, and Sewell WA

Journal of immunology (Baltimore, Md. : 1950) 180(4):2600-7, 2008 Feb 15 - Who cited this? | PubMed ID: 18250471 | Fulltext

Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2.

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Lee H, Whitfeld PL, and Mackay CR

Immunology and cell biology 86(2):153-60, 2008 Feb - Who cited this? | PubMed ID: 18227853 | Fulltext

T Follicular Helper (T(FH)) Cells in Normal and Dysregulated Immune Responses.

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King C, Tangye SG, and Mackay CR

Annual review of immunology 26:741-66, 2008 - Who cited this? | PubMed ID: 18173374 | Fulltext

Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7.

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Sierro F, Biben C, Martínez-Muñoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martínez-A C, Mackay CR, and Mackay F

Proceedings of the National Academy of Sciences of the United States of America 104(37):14759, 2007 Sep 11 - Who cited this? | PubMed ID: 17804806 | Fulltext

BAFF and MyD88 signals promote a lupuslike disease independent of T cells.

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Groom JR, Fletcher CA, Walters SN, Grey ST, Watt SV, Sweet MJ, Smyth MJ, Mackay CR, and Mackay F

The Journal of experimental medicine 204(8):1959, 2007 Aug 6 - Who cited this? | PubMed ID: 17664289 | Fulltext

Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses.

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Jeffrey KL, Camps M, Rommel C, and Mackay CR

Nature reviews. Drug discovery 6(5):391-403, 2007 May - Who cited this? | PubMed ID: 17473844 | Fulltext

Regulation of dendritic cell function and T cell priming by the fatty acid-binding protein AP2.

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Rolph MS, Young TR, Shum BO, Gorgun CZ, Schmitz-Peiffer C, Ramshaw IA, Hotamisligil GS, and Mackay CR

Journal of immunology (Baltimore, Md. : 1950) 177(11):7794, 2006 Dec 1 - Who cited this? | PubMed ID: 17114450 | Fulltext

Targeting BAFF: immunomodulation for autoimmune diseases and lymphomas.

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Sutherland AP, Mackay F, and Mackay CR

Pharmacology & therapeutics 112(3):774-86, 2006 Dec - Who cited this? | PubMed ID: 16863659 | Fulltext

Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies.

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Lee H, Zahra D, Vogelzang A, Newton R, Thatcher J, Quan A, So T, Zwirner J, Koentgen F, Padkjaer SB, Mackay F, Whitfeld PL, and Mackay CR

Nature biotechnology 24(10):1279-84, 2006 Oct - Who cited this? | PubMed ID: 16980974 | Fulltext

A new role for CCR5 in innate immunity--binding to bacterial heat shock protein 70.

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Mackay CR and Sallusto F

European journal of immunology 36(9):2293-5, 2006 Sep - Who cited this? | PubMed ID: 16933363 | Fulltext

Immune cell transcriptome datasets reveal novel leukocyte subset-specific genes and genes associated with allergic processes.

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Liu SM, Xavier R, Good KL, Chtanova T, Newton R, Sisavanh M, Zimmer S, Deng C, Silva DG, Frost MJ, Tangye SG, Rolph MS, and Mackay CR

The Journal of allergy and clinical immunology 118(2):496-503, 2006 Aug - Who cited this? | PubMed ID: 16890777 | Fulltext

The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation.

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Shum BO, Mackay CR, Gorgun CZ, Frost MJ, Kumar RK, Hotamisligil GS, and Rolph MS

The Journal of clinical investigation 116(8):2183-2192, 2006 Aug - Who cited this? | PubMed ID: 16841093 | Fulltext

Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1.

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Jeffrey KL, Brummer T, Rolph MS, Liu SM, Callejas NA, Grumont RJ, Gillieron C, Mackay F, Grey S, Camps M, Rommel C, Gerondakis SD, and Mackay CR

Nature immunology 7(3):274, 2006 Mar - Who cited this? | PubMed ID: 16474395 | Fulltext

Clues to asthma pathogenesis from microarray expression studies.

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Rolph MS, Sisavanh M, Liu SM, and Mackay CR

Pharmacology & therapeutics 109(1-2):284-94, 2006 Jan - Who cited this? | PubMed ID: 16203040 | Fulltext

Identification of T cell-restricted genes, and signatures for different T cell responses, using a comprehensive collection of microarray datasets.

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Chtanova T, Newton R, Liu SM, Weininger L, Young TR, Silva DG, Bertoni F, Rinaldi A, Chappaz S, Sallusto F, Rolph MS, and Mackay CR

Journal of immunology (Baltimore, Md. : 1950) 175(12):7837-47, 2005 Dec 15 - Who cited this? | PubMed ID: 16339519 | Fulltext

A fundamental bimodal role for neuropeptide Y1 receptor in the immune system.

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Wheway J, Mackay CR, Newton RA, Sainsbury A, Boey D, Herzog H, and Mackay F

The Journal of experimental medicine 202(11):1527-38, 2005 Dec 5 - Who cited this? | PubMed ID: 16330815 | Fulltext

Follicular B helper T cells in antibody responses and autoimmunity.

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Vinuesa CG, Tangye SG, Moser B, and Mackay CR

Nature reviews. Immunology 5(11):853, 2005 Nov - Who cited this? | PubMed ID: 16261173 | Fulltext

BAFF-R, the major B cell-activating factor receptor, is expressed on most mature B cells and B-cell lymphoproliferative disorders.

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Rodig SJ, Shahsafaei A, Li B, Mackay CR, and Dorfman DM

Human pathology 36(10):1113-9, 2005 Oct - Who cited this? | PubMed ID: 16226112 | Fulltext

Gene profiling in atherosclerosis reveals a key role for small inducible cytokines: validation using a novel monocyte chemoattractant protein monoclonal antibody.

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Lutgens E, Faber B, Schapira K, Evelo CT, van Haaften R, Heeneman S, Cleutjens KB, Bijnens AP, Beckers L, Porter JG, Mackay CR, Rennert P, Bailly V, Jarpe M, Dolinski B, Koteliansky V,

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Circulation 111(25):3443-52, 2005 Jun 28 - Who cited this? | PubMed ID: 15967845 | Fulltext

BAFF augments certain Th1-associated inflammatory responses.

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Sutherland AP, Ng LG, Fletcher CA, Shum B, Newton RA, Grey ST, Rolph MS, Mackay F, and Mackay CR

Journal of immunology (Baltimore, Md. : 1950) 174(9):5537, 2005 May 1 - Who cited this? | PubMed ID: 15843552 | Fulltext

The BAFF/APRIL system: life beyond B lymphocytes.

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Ng LG, Mackay CR, and Mackay F

Molecular immunology 42(7):763-72, 2005 May - Who cited this? | PubMed ID: 15829264 | Fulltext

CCL3L1 dose and HIV-1 susceptibility.

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Mackay CR

Trends in molecular medicine 11(5):203-6, 2005 May - Who cited this? | PubMed ID: 15882607 | Fulltext

Contribution of stromal cells to the migration, function and retention of plasma cells in human spleen: potential roles of CXCL12, IL-6 and CD54.

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Ellyard JI, Avery DT, Mackay CR, and Tangye SG

European journal of immunology 35(3):699-708, 2005 Mar - Who cited this? | PubMed ID: 15714584 | Fulltext

Overlapping gene expression profiles in rheumatoid fibroblast-like synoviocytes induced by the proinflammatory cytokines interleukin-1 beta and tumor necrosis factor.

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Taberner M, Scott KF, Weininger L, Mackay CR, and Rolph MS

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 54(1):10-6, 2005 Jan - Who cited this? | PubMed ID: 15723199 | Fulltext

Chemoattractants and their receptors in homeostasis and inflammation.

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Sallusto F and Mackay CR

Current opinion in immunology 16(6):724-31, 2004 Dec - Who cited this? | PubMed ID: 15511664 | Fulltext

B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells.

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Ng LG, Sutherland AP, Newton R, Qian F, Cachero TG, Scott ML, Thompson JS, Wheway J, Chtanova T, Groom J, Sutton IJ, Xin C, Tangye SG, Kalled SL, Mackay F, and Mackay CR

Journal of immunology (Baltimore, Md. : 1950) 173(2):807, 2004 Jul 15 - Who cited this? | PubMed ID: 15240667 | Fulltext

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells.

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Chtanova T, Tangye SG, Newton R, Frank N, Hodge MR, Rolph MS, and Mackay CR

Journal of immunology (Baltimore, Md. : 1950) 173(1):68-78, 2004 Jul 1 - Who cited this? | PubMed ID: 15210760 | Fulltext

Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection.

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Zaunders JJ, Dyer WB, Wang B, Munier ML, Miranda-Saksena M, Newton R, Moore J, Mackay CR, Cooper DA, Saksena NK, and Kelleher AD

Blood 103(6):2238, 2004 Mar 15 - Who cited this? | PubMed ID: 14645006 | Fulltext

TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma.

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Batten M, Fletcher C, Ng LG, Groom J, Wheway J, Laâbi Y, Xin X, Schneider P, Tschopp J, Mackay CR, and Mackay F

Journal of immunology (Baltimore, Md. : 1950) 172(2):812-22, 2004 Jan 15 - Who cited this? | PubMed ID: 14707051 | Fulltext

Levels of BAFF in serum in primary biliary cirrhosis and autoimmune diabetes.

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Mackay IR, Groom J, and Mackay CR

Autoimmunity 35(8):551-3, 2002 Dec - Who cited this? | PubMed ID: 12765482 | Fulltext

The role of BAFF in B-cell maturation, T-cell activation and autoimmunity.

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Mackay F and Mackay CR

Trends in immunology 23(3):113-5, 2002 Mar - Who cited this? | PubMed ID: 11864827 | Fulltext

New avenues for anti-inflammatory therapy.

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Mackay CR

Nature medicine 8(2):117-8, 2002 Feb - Who cited this? | PubMed ID: 11821893 | Fulltext

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome.

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Groom J, Kalled SL, Cutler AH, Olson C, Woodcock SA, Schneider P, Tschopp J, Cachero TG, Batten M, Wheway J, Mauri D, Cavill D, Gordon TP, Mackay CR, and Mackay F

The Journal of clinical investigation 109(1):59-68, 2002 Jan - Who cited this? | PubMed ID: 11781351 | Fulltext

Gene microarrays reveal extensive differential gene expression in both CD4(+) and CD8(+) type 1 and type 2 T cells.

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Chtanova T, Kemp RA, Sutherland AP, Ronchese F, and Mackay CR

Journal of immunology (Baltimore, Md. : 1950) 167(6):3057, 2001 Sep 15 - Who cited this? | PubMed ID: 11544289 | Fulltext

Immunology. Memory T cells--local heroes in the struggle for immunity.

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Mackay CR and von Andrian UH

Science (New York, N.Y.) 291(5512):2323-4, 2001 Mar 23 - Who cited this? | PubMed ID: 11269302 | Fulltext

Chemokines: immunology's high impact factors.

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Mackay CR

Nature immunology 2(2):95-101, 2001 Feb - Who cited this? | PubMed ID: 11175800 | Fulltext

Monocyte chemotactic protein-1, -2, and -3 are distinctively expressed in portal tracts and granulomata in primary biliary cirrhosis: implications for pathogenesis.

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Tsuneyama K, Harada K, Yasoshima M, Hiramatsu K, Mackay CR, Mackay IR, Gershwin ME, and Nakanuma Y

The Journal of pathology 193(1):102-9, 2001 Jan - Who cited this? | PubMed ID: 11169522 | Fulltext

T cell effector subsets: extending the Th1/Th2 paradigm.

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Chtanova T and Mackay CR

Advances in immunology 78:233-66, 2001 - Who cited this? | PubMed ID: 11432205 | Fulltext

The question of method in ethics consultation: the IRB frontier.

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MacKay CR

The American journal of bioethics : AJOB 1(4):50-2, 2001 - Who cited this? | PubMed ID: 11954641 | Fulltext

Commentary on "Genetic testing for hereditary disease".

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MacKay CR

The Journal of clinical ethics 12(4):373-4, 2001 - Who cited this? | PubMed ID: 12026742 | Fulltext

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