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Papers authored by Losordo DW

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The Hedgehog transcription factor Gli3 modulates angiogenesis.

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Renault MA, Roncalli J, Tongers J, Misener S, Thorne T, Jujo K, Ito A, Clarke T, Fung C, Millay M, Kamide C, Scarpelli A, Klyachko E, and Losordo DW

Circulation research 105(8):818-26, 2009 Oct 9 - Who cited this? | PubMed ID: 19729595 | Fulltext

Human studies of angiogenic gene therapy.

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Gupta R, Tongers J, and Losordo DW

Circulation research 105(8):724-36, 2009 Oct 9 - Who cited this? | PubMed ID: 19815827 | Fulltext

Regulation of vascular contractility and blood pressure by the E2F2 transcription factor.

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Zhou J, Zhu Y, Cheng M, Dinesh D, Thorne T, Poh KK, Liu D, Botros C, Tang YL, Reisdorph N, Kishore R, Losordo DW, and Qin G

Circulation 120(13):1213-21, 2009 Sep 29 - Who cited this? | PubMed ID: 19752322 | Fulltext

Adrenal androgen dehydroepiandrosterone sulfate inhibits vascular remodeling following arterial injury.

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Ii M, Hoshiga M, Negoro N, Fukui R, Nakakoji T, Kohbayashi E, Shibata N, Furutama D, Ishihara T, Hanafusa T, Losordo DW, and Ohsawa N

Atherosclerosis 206(1):77-85, 2009 Sep - Who cited this? | PubMed ID: 19298964 | Fulltext

Hypoxic preconditioning enhances the benefit of cardiac progenitor cell therapy for treatment of myocardial infarction by inducing CXCR4 expression.

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Tang YL, Zhu W, Cheng M, Chen L, Zhang J, Sun T, Kishore R, Phillips MI, Losordo DW, and Qin G

Circulation research 104(10):1209-16, 2009 May 22 - Who cited this? | PubMed ID: 19407239 | Fulltext

The relative potency and safety of endothelial progenitor cells and unselected mononuclear cells for recovery from myocardial infarction and ischemia.

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Sekiguchi H, Ii M, and Losordo DW

Journal of cellular physiology 219(2):235-42, 2009 May - Who cited this? | PubMed ID: 19115244 | Fulltext

Estradiol-induced, endothelial progenitor cell-mediated neovascularization in male mice with hind-limb ischemia.

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Ruifrok WP, de Boer RA, Iwakura A, Silver M, Kusano K, Tio RA, and Losordo DW

Vascular medicine (London, England) 14(1):29-36, 2009 Feb - Who cited this? | PubMed ID: 19144777 | Fulltext

IL-10 Inhibits Inflammation and Attenuates Left Ventricular Remodeling After Myocardial Infarction via Activation of STAT3 and Suppression of HuR.

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Krishnamurthy P, Rajasingh J, Lambers E, Qin G, Losordo DW, and Kishore R

Circulation research 104(2):e9-e18, 2009 Jan 30 - Who cited this? | PubMed ID: 19096025 | Fulltext

A big promise from the very small identification of circulating embryonic stem-like pluripotent cells in patients with acute myocardial infarction.

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Losordo DW and Kishore R

Journal of the American College of Cardiology 53(1):10-2, 2009 Jan 6 - Who cited this? | PubMed ID: 19118717 | Fulltext

Bioengineering to enhance progenitor cell therapeutics.

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Tongers J, Webber MJ, and Losordo DW

Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 36(2):140-4, 2009 - Who cited this? | PubMed ID: 19436808 | Fulltext

Endothelial progenitor cells in neovascularization of infarcted myocardium.

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Jujo K, Ii M, and Losordo DW

Journal of molecular and cellular cardiology 45(4):530-44, 2008 Oct - Who cited this? | PubMed ID: 18755197 | Fulltext

Sonic Hedgehog Regulates Angiogenesis and Myogenesis During Post-Natal Skeletal Muscle Regeneration.

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Straface G, Aprahamian T, Flex A, Gaetani E, Biscetti F, Smith RC, Pecorini G, Pola E, Angelini F, Stigliano E, Castellot JJ, Losordo DW, and Pola R

Journal of cellular and molecular medicine, 2008 Jul 26 - Who cited this? | PubMed ID: 18662193 | Fulltext

A "hawk's beak" to identify the new transient midventricular Tako-Tsubo syndrome.

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Roncalli J, Carrie D, Fauvel JM, and Losordo DW

International journal of cardiology 127(3):e179-80, 2008 Jul 21 - Who cited this? | PubMed ID: 17683813 | Fulltext

Therapeutic angiogenesis for critical limb ischemia: microvascular therapies coming of age.

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Tongers J, Roncalli JG, and Losordo DW

Circulation 118(1):9-16, 2008 Jul 1 - Who cited this? | PubMed ID: 18591450 | Fulltext

Biological approaches to ischemic tissue repair: gene- and cell-based strategies.

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Roncalli J, Tongers J, Renault MA, and Losordo DW

Expert review of cardiovascular therapy 6(5):653-68, 2008 Jun - Who cited this? | PubMed ID: 18510483 | Fulltext

Cell-Free Embryonic Stem Cell Extract-Mediated Derivation of Multipotent Stem Cells From NIH3T3 Fibroblasts for Functional and Anatomical Ischemic Tissue Repair.

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Rajasingh J, Lambers E, Hamada H, Bord E, Thorne T, Goukassian I, Krishnamurthy P, Rosen KM, Ahluwalia D, Zhu Y, Qin G, Losordo DW, and Kishore R

Circulation research, 2008 May 15 - Who cited this? | PubMed ID: 18483406 | Fulltext

Endothelial progenitor cells in regenerative medicine and cancer: a decade of research.

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Roncalli JG, Tongers J, Renault MA, and Losordo DW

Trends in biotechnology 26(5):276-83, 2008 May - Who cited this? | PubMed ID: 18359114 | Fulltext

Endothelial progenitor cells for cardiovascular regeneration.

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Kawamoto A and Losordo DW

Trends in cardiovascular medicine 18(1):33-7, 2008 Jan - Who cited this? | PubMed ID: 18206807 | Fulltext

Frontiers in nephrology: the evolving therapeutic applications of endothelial progenitor cells.

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Tongers J and Losordo DW

Journal of the American Society of Nephrology : JASN 18(11):2843-52, 2007 Nov - Who cited this? | PubMed ID: 17942950 | Fulltext

Pulmonary gas transfer related to markers of angiogenesis during the menstrual cycle.

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Farha S, Asosingh K, Laskowski D, Licina L, Sekigushi H, Losordo DW, Dweik RA, Wiedemann HP, and Erzurum SC

Journal of applied physiology (Bethesda, Md. : 1985) 103(5):1789-95, 2007 Nov - Who cited this? | PubMed ID: 17717117 | Fulltext

STAT3-dependent mouse embryonic stem cell differentiation into cardiomyocytes: analysis of molecular signaling and therapeutic efficacy of cardiomyocyte precommitted mES transplantation in a mouse model of myocardial infarction.

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Rajasingh J, Bord E, Hamada H, Lambers E, Qin G, Losordo DW, and Kishore R

Circulation research 101(9):910, 2007 Oct 26 - Who cited this? | PubMed ID: 17823373 | Fulltext

Hypoxia up-regulates the angiogenic cytokine secretoneurin via an HIF-1alpha- and basic FGF-dependent pathway in muscle cells.

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Egger M, Schgoer W, Beer AG, Jeschke J, Leierer J, Theurl M, Frauscher S, Tepper OM, Niederwanger A, Ritsch A, Kearney M, Wanschitz J, Gurtner GC, Fischer-Colbrie R, Weiss G, Piza-Katzer H,

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The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 21(11):2906, 2007 Sep - Who cited this? | PubMed ID: 17504977 | Fulltext

Enhanced voluntary alcohol consumption after estrogen supplementation negates estrogen-mediated vascular repair in ovariectomized mice.

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Rajasingh J, Bord E, Qin G, Ii M, Silver M, Hamada H, Ahluwalia D, Goukassian D, Zhu Y, Losordo DW, and Kishore R

Endocrinology 148(8):3618-24, 2007 Aug - Who cited this? | PubMed ID: 17478555 | Fulltext

Intramyocardial transplantation of autologous CD34+ stem cells for intractable angina: a phase I/IIa double-blind, randomized controlled trial.

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Losordo DW, Schatz RA, White CJ, Udelson JE, Veereshwarayya V, Durgin M, Poh KK, Weinstein R, Kearney M, Chaudhry M, Burg A, Eaton L, Heyd L, Thorne T, Shturman L, Hoffmeister P,

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Circulation 115(25):3165, 2007 Jun 26 - Who cited this? | PubMed ID: 17562958 | Fulltext

Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing.

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Maruyama K, Asai J, Ii M, Thorne T, Losordo DW, and D'Amore PA

The American journal of pathology 170(4):1178, 2007 Apr - Who cited this? | PubMed ID: 17392158 | Fulltext

The matrix revolutions: matrix metalloproteinase, vasculogenesis, and ischemic tissue repair.

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Renault MA and Losordo DW

Circulation research 100(6):749-50, 2007 Mar 30 - Who cited this? | PubMed ID: 17395877 | Fulltext

Gene therapy for restenosis: biological solution to a biological problem.

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Kishore R and Losordo DW

Journal of molecular and cellular cardiology 42(3):461-8, 2007 Mar - Who cited this? | PubMed ID: 17222423 | Fulltext

Tumor necrosis factor-alpha receptor p75 is required in ischemia-induced neovascularization.

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Goukassian DA, Qin G, Dolan C, Murayama T, Silver M, Curry C, Eaton E, Luedemann C, Ma H, Asahara T, Zak V, Mehta S, Burg A, Thorne T, Kishore R, and Losordo DW

Circulation 115(6):752, 2007 Feb 13 - Who cited this? | PubMed ID: 17261656 | Fulltext

Long-term stable expression of human growth hormone by rAAV promotes myocardial protection post-myocardial infarction.

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Kusano K, Tsutsumi Y, Dean J, Gavin M, Ma H, Silver M, Thorne T, Zhu Y, Losordo DW, and Aikawa R

Journal of molecular and cellular cardiology 42(2):390-9, 2007 Feb - Who cited this? | PubMed ID: 17174322 | Fulltext

Critical role of endothelial Notch1 signaling in postnatal angiogenesis.

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Takeshita K, Satoh M, Ii M, Silver M, Limbourg FP, Mukai Y, Rikitake Y, Radtke F, Gridley T, Losordo DW, and Liao JK

Circulation research 100(1):70, 2007 Jan 5 - Who cited this? | PubMed ID: 17158336 | Fulltext

Statins and the endothelium.

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Ii M and Losordo DW

Vascular pharmacology 46(1):1-9, 2007 Jan - Who cited this? | PubMed ID: 16920035 | Fulltext

Ischemic tissue repair by autologous bone marrow-derived stem cells: scientific basis and preclinical data.

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Quraishi A and Losordo DW

Handbook of experimental pharmacology(180):167-79, 2007 - Who cited this? | PubMed ID: 17554508 | Fulltext

Therapeutic Angiogenesis Inhibits or Rescues Chemotherapy-induced Peripheral Neuropathy: Taxol- and Thalidomide-induced Injury of Vasa Nervorum is Ameliorated by VEGF.

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Kirchmair R, Tietz AB, Panagiotou E, Walter DH, Silver M, Yoon YS, Schratzberger P, Weber A, Kusano K, Weinberg DH, Ropper AH, Isner JM, and Losordo DW

Molecular therapy : the journal of the American Society of Gene Therapy 15(1):69-75, 2007 Jan - Who cited this? | PubMed ID: 17164777 | Fulltext

Therapeutic myocardial angiogenesis.

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Renault MA and Losordo DW

Microvascular research 74(2-3):159-71, 2007 - Who cited this? | PubMed ID: 17950369 | Fulltext

Estrogen receptors alpha and beta mediate contribution of bone marrow-derived endothelial progenitor cells to functional recovery after myocardial infarction.

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Hamada H, Kim MK, Iwakura A, Ii M, Thorne T, Qin G, Asai J, Tsutsumi Y, Sekiguchi H, Silver M, Wecker A, Bord E, Zhu Y, Kishore R, and Losordo DW

Circulation 114(21):2261, 2006 Nov 21 - Who cited this? | PubMed ID: 17088460 | Fulltext

CD34-positive cells exhibit increased potency and safety for therapeutic neovascularization after myocardial infarction compared with total mononuclear cells.

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Kawamoto A, Iwasaki H, Kusano K, Murayama T, Oyamada A, Silver M, Hulbert C, Gavin M, Hanley A, Ma H, Kearney M, Zak V, Asahara T, and Losordo DW

Circulation 114(20):2163-9, 2006 Nov 14 - Who cited this? | PubMed ID: 17075009 | Fulltext

Derivation and characterization of bone marrow-derived multipotent stem cells.

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Lee J, Wecker A, Losordo DW, and Yoon YS

Experimental hematology 34(11):1602-3, 2006 Nov - Who cited this? | PubMed ID: 17046582 | Fulltext

IL-10-induced TNF-alpha mRNA destabilization is mediated via IL-10 suppression of p38 MAP kinase activation and inhibition of HuR expression.

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Rajasingh J, Bord E, Luedemann C, Asai J, Hamada H, Thorne T, Qin G, Goukassian D, Zhu Y, Losordo DW, and Kishore R

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20(12):2112, 2006 Oct - Who cited this? | PubMed ID: 16935932 | Fulltext

Netrins promote developmental and therapeutic angiogenesis.

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Wilson BD, Ii M, Park KW, Suli A, Sorensen LK, Larrieu-Lahargue F, Urness LD, Suh W, Asai J, Kock GA, Thorne T, Silver M, Thomas KR, Chien CB, Losordo DW, and Li DY

Science (New York, N.Y.) 313(5787):640-4, 2006 Aug 4 - Who cited this? | PubMed ID: 16809490 | Fulltext

Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF.

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Qin G, Kishore R, Dolan CM, Silver M, Wecker A, Luedemann CN, Thorne T, Hanley A, Curry C, Heyd L, Dinesh D, Kearney M, Martelli F, Murayama T, Goukassian DA, Zhu Y,

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Proceedings of the National Academy of Sciences of the United States of America 103(29):11015-20, 2006 Jul 18 - Who cited this? | PubMed ID: 16835303 | Fulltext

Topical sonic hedgehog gene therapy accelerates wound healing in diabetes by enhancing endothelial progenitor cell-mediated microvascular remodeling.

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Asai J, Takenaka H, Kusano KF, Ii M, Luedemann C, Curry C, Eaton E, Iwakura A, Tsutsumi Y, Hamada H, Kishimoto S, Thorne T, Kishore R, and Losordo DW

Circulation 113(20):2413-24, 2006 May 23 - Who cited this? | PubMed ID: 16702471 | Fulltext

Estradiol enhances recovery after myocardial infarction by augmenting incorporation of bone marrow-derived endothelial progenitor cells into sites of ischemia-induced neovascularization via endothelial nitric oxide synthase-mediated activation of matrix m.

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Iwakura A, Shastry S, Luedemann C, Hamada H, Kawamoto A, Kishore R, Zhu Y, Qin G, Silver M, Thorne T, Eaton L, Masuda H, Asahara T, and Losordo DW

Circulation 113(12):1605, 2006 Mar 28 - Who cited this? | PubMed ID: 16534014 | Fulltext

Endothelial progenitor thrombospondin-1 mediates diabetes-induced delay in reendothelialization following arterial injury.

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Ii M, Takenaka H, Asai J, Ibusuki K, Mizukami Y, Maruyama K, Yoon YS, Wecker A, Luedemann C, Eaton E, Silver M, Thorne T, and Losordo DW

Circulation research 98(5):697, 2006 Mar 17 - Who cited this? | PubMed ID: 16484619 | Fulltext

Cell therapy for acute myocardial infarction: curb your enthusiasm?.

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Welt FG and Losordo DW

Circulation 113(10):1272-4, 2006 Mar 14 - Who cited this? | PubMed ID: 16534025 | Fulltext

Synergistic effect of combined intramyocardial CD34+ cells and VEGF2 gene therapy after MI.

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Shintani S, Kusano K, Ii M, Iwakura A, Heyd L, Curry C, Wecker A, Gavin M, Ma H, Kearney M, Silver M, Thorne T, Murohara T, and Losordo DW

Nature clinical practice. Cardiovascular medicine 3 Suppl 1:S123-8, 2006 Mar - Who cited this? | PubMed ID: 16501618 | Fulltext

Functional disruption of alpha4 integrin mobilizes bone marrow-derived endothelial progenitors and augments ischemic neovascularization.

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Qin G, Ii M, Silver M, Wecker A, Bord E, Ma H, Gavin M, Goukassian DA, Yoon YS, Papayannopoulou T, Asahara T, Kearney M, Thorne T, Curry C, Eaton L, Heyd L,

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The Journal of experimental medicine 203(1):153-63, 2006 Jan 23 - Who cited this? | PubMed ID: 16401693 | Fulltext

Atherosclerosis 2005: recent discoveries and novel hypotheses.

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Goldschmidt-Clermont PJ, Creager MA, Losordo DW, Lam GK, Wassef M, and Dzau VJ

Circulation 112(21):3348-53, 2005 Nov 22 - Who cited this? | PubMed ID: 16301361 | Fulltext

Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic signaling.

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Kusano KF, Pola R, Murayama T, Curry C, Kawamoto A, Iwakura A, Shintani S, Ii M, Asai J, Tkebuchava T, Thorne T, Takenaka H, Aikawa R, Goukassian D, von Samson P, Hamada H,

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Nature medicine 11(11):1197-204, 2005 Nov - Who cited this? | PubMed ID: 16244652 | Fulltext

Inflammation-induced lymphangiogenesis in the cornea arises from CD11b-positive macrophages.

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Maruyama K, Ii M, Cursiefen C, Jackson DG, Keino H, Tomita M, Van Rooijen N, Takenaka H, D'Amore PA, Stein-Streilein J, Losordo DW, and Streilein JW

The Journal of clinical investigation 115(9):2363-72, 2005 Sep - Who cited this? | PubMed ID: 16138190 | Fulltext

Double face of VEGF.

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Tsutsumi Y and Losordo DW

Circulation 112(9):1248-50, 2005 Aug 30 - Who cited this? | PubMed ID: 16129810 | Fulltext

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