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Papers authored by Libby P

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Spatiotemporal controlled delivery of nanoparticles to injured vasculature.

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Chan JM, Zhang L, Tong R, Ghosh D, Gao W, Liao G, Yuet KP, Gray D, Rhee JW, Cheng J, Golomb G, Libby P, Langer R, and Farokhzad OC

Proceedings of the National Academy of Sciences of the United States of America 107(5):2213-8, 2010 Feb 2 - Who cited this? | PubMed ID: 20133865 | Fulltext

Inflammation in atherosclerosis:.

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Libby P, Okamoto Y, Rocha VZ, and Folco E

Circulation journal : official journal of the Japanese Circulation Society 74(2):213-20, 2010 Feb - Who cited this? | PubMed ID: 20065609 | Fulltext

Adaptive immunity and atherosclerosis.

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Andersson J, Libby P, and Hansson GK

Clinical immunology (Orlando, Fla.) 134(1):33-46, 2010 Jan - Who cited this? | PubMed ID: 19635683 | Fulltext

Inflammation in atherosclerosis from pathophysiology to practice.

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Libby P, Ridker PM, Hansson GK, and Leducq Transatlantic Network on Atherothrombosis

Journal of the American College of Cardiology 54(23):2129-38, 2009 Dec 1 - Who cited this? | PubMed ID: 19942084 | Fulltext

CC Chemokine Receptor-1 Activates Intimal Smooth Muscle-Like Cells in Graft Arterial Disease.

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Shimizu K, Minami M, Shubiki R, Lopez-Ilasaca M, Macfarlane L, Asami Y, Li Y, Mitchell RN, and Libby P

Circulation 120(18):1800-13, 2009 Nov 3 - Who cited this? | PubMed ID: 19841301 | Fulltext

Number needed to treat with rosuvastatin to prevent first cardiovascular events and death among men and women with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin (JUPITER).

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Ridker PM, MacFadyen JG, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ, and JUPITER Study Group

Circulation. Cardiovascular quality and outcomes 2(6):616-23, 2009 Nov - Who cited this? | PubMed ID: 20031900 | Fulltext

Adiponectin inhibits allograft rejection in murine cardiac transplantation.

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Okamoto Y, Christen T, Shimizu K, Asano K, Kihara S, Mitchell RN, and Libby P

Transplantation 88(7):879-83, 2009 Oct 15 - Who cited this? | PubMed ID: 19935458 | Fulltext

Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling.

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Medoff BD, Okamoto Y, Leyton P, Weng M, Sandall BP, Raher MJ, Kihara S, Bloch KD, Libby P, and Luster AD

American journal of respiratory cell and molecular biology 41(4):397-406, 2009 Oct - Who cited this? | PubMed ID: 19168697 | Fulltext

Endogenous tissue plasminogen activator and risk of recurrent cardiac events after an acute coronary syndrome in the MIRACL study.

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Kinlay S, Schwartz GG, Olsson AG, Rifai N, Bao W, Libby P, Ganz P, and Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) Study Investigators

Atherosclerosis 206(2):551-5, 2009 Oct - Who cited this? | PubMed ID: 19394618 | Fulltext

(18)F-4V for PET-CT Imaging of VCAM-1 Expression in Atherosclerosis.

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Nahrendorf M, Keliher E, Panizzi P, Zhang H, Hembrador S, Figueiredo JL, Aikawa E, Kelly K, Libby P, and Weissleder R

JACC. Cardiovascular imaging 2(10):1213-22, 2009 Oct - Who cited this? | PubMed ID: 19833312 | Fulltext

Adiponectin Inhibits Pro-inflammatory Signaling in Human Macrophages Independent of Interleukin-10.

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Folco EJ, Rocha VZ, López-Ilasaca M, and Libby P

The Journal of biological chemistry 284(38):25569-75, 2009 Sep 18 - Who cited this? | PubMed ID: 19617629 | Fulltext

Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation.

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Sun J, Zhang J, Lindholt JS, Sukhova GK, Liu J, He A, Abrink M, Pejler G, Stevens RL, Thompson RW, Ennis TL, Gurish MF, Libby P, and Shi GP

Circulation 120(11):973-82, 2009 Sep 15 - Who cited this? | PubMed ID: 19720934 | Fulltext

Kruppel-like Factor KLF10 Targets Transforming Growth Factor-{beta}1 to Regulate CD4+CD25- T Cells and T Regulatory Cells.

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Cao Z, Wara AK, Icli B, Sun X, Packard RR, Esen F, Stapleton CJ, Subramaniam M, Kretschmer K, Apostolou I, von Boehmer H, Hansson GK, Spelsberg TC, Libby P, and Feinberg MW

The Journal of biological chemistry 284(37):24914-24, 2009 Sep 11 - Who cited this? | PubMed ID: 19602726 | Fulltext

A winter's tale: report from the First Annual Canadian Biomarkers and Surrogate Endpoints Symposium.

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Heinonen T, Waters DD, Libby P, and Tardif JC

The Canadian journal of cardiology 25(9):527-32, 2009 Sep - Who cited this? | PubMed ID: 19746243 | Fulltext

Myeloid-related protein-8/14 is critical for the biological response to vascular injury.

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Croce K, Gao H, Wang Y, Mooroka T, Sakuma M, Shi C, Sukhova GK, Packard RR, Hogg N, Libby P, and Simon DI

Circulation 120(5):427-36, 2009 Aug 4 - Who cited this? | PubMed ID: 19620505 | Fulltext

Current Good Manufacturing Practices for PET Drug Products in the United States.

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Swanson D, Graham M, Heinonen TM, Libby P, and Mills GQ

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 50(8):26N-8N, 2009 Aug - Who cited this? | PubMed ID: 19652213 | Fulltext

Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice.

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Liu J, Divoux A, Sun J, Zhang J, Clément K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, and Shi GP

Nature medicine 15(8):940-5, 2009 Aug - Who cited this? | PubMed ID: 19633655 | Fulltext

Identification of splenic reservoir monocytes and their deployment to inflammatory sites.

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Swirski FK, Nahrendorf M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, and Pittet MJ

Science (New York, N.Y.) 325(5940):612-6, 2009 Jul 31 - Who cited this? | PubMed ID: 19644120 | Fulltext

Optical and multimodality molecular imaging: insights into atherosclerosis.

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Jaffer FA, Libby P, and Weissleder R

Arteriosclerosis, thrombosis, and vascular biology 29(7):1017-24, 2009 Jul - Who cited this? | PubMed ID: 19359659 | Fulltext

The American Journal of Cardiology and Journal of Periodontology Editors' Consensus: Periodontitis and Atherosclerotic Cardiovascular Disease (diamond).

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Friedewald VE, Kornman KS, Beck JD, Genco R, Goldfine A, Libby P, Offenbacher S, Ridker PM, Van Dyke TE, and Roberts WC

Journal of periodontology 80(7):1021-32, 2009 Jul - Who cited this? | PubMed ID: 19563277 | Fulltext

Safety and efficacy of achieving very low low-density lipoprotein cholesterol levels with rosuvastatin 40 mg daily (from the ASTEROID Study).

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Wiviott SD, Mohanavelu S, Raichlen JS, Cain VA, Nissen SE, and Libby P

The American journal of cardiology 104(1):29-35, 2009 Jul 1 - Who cited this? | PubMed ID: 19576317 | Fulltext

The American Journal of Cardiology and Journal of Periodontology Editors' Consensus: periodontitis and atherosclerotic cardiovascular disease.

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Friedewald VE, Kornman KS, Beck JD, Genco R, Goldfine A, Libby P, Offenbacher S, Ridker PM, Van Dyke TE, and Roberts WC

The American journal of cardiology 104(1):59-68, 2009 Jul 1 - Who cited this? | PubMed ID: 19576322 | Fulltext

Relationship of oxidized phospholipids and biomarkers of oxidized low-density lipoprotein with cardiovascular risk factors, inflammatory biomarkers, and effect of statin therapy in patients with acute coronary syndromes: Results from the MIRACL (Myocardial Ischemia Reduction With Aggressive Cholesterol Lowering) trial.

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Fraley AE, Schwartz GG, Olsson AG, Kinlay S, Szarek M, Rifai N, Libby P, Ganz P, Witztum JL, Tsimikas S, and MIRACL Study Investigators

Journal of the American College of Cardiology 53(23):2186-96, 2009 Jun 9 - Who cited this? | PubMed ID: 19497447 | Fulltext

Obesity, inflammation, and atherosclerosis.

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Rocha VZ and Libby P

Nature reviews. Cardiology 6(6):399-409, 2009 Jun - Who cited this? | PubMed ID: 19399028 | Fulltext

Innate and adaptive immunity in atherosclerosis.

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Packard RR, Lichtman AH, and Libby P

Seminars in immunopathology 31(1):5-22, 2009 Jun - Who cited this? | PubMed ID: 19449008 | Fulltext

A randomized trial of rosuvastatin in the prevention of venous thromboembolism.

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Glynn RJ, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, and Ridker PM

The New England journal of medicine 360(18):1851-61, 2009 Apr 30 - Who cited this? | PubMed ID: 19329822 | Fulltext

Molecular imaging of innate immune cell function in transplant rejection.

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Christen T, Nahrendorf M, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, and Libby P

Circulation 119(14):1925-32, 2009 Apr 14 - Who cited this? | PubMed ID: 19332470 | Fulltext

Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease.

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Aikawa E, Aikawa M, Libby P, Figueiredo JL, Rusanescu G, Iwamoto Y, Fukuda D, Kohler RH, Shi GP, Jaffer FA, and Weissleder R

Circulation 119(13):1785-94, 2009 Apr 7 - Who cited this? | PubMed ID: 19307473 | Fulltext

Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial.

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Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, Macfadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ, and JUPITER Trial Study Group

Lancet 373(9670):1175-82, 2009 Apr 4 - Who cited this? | PubMed ID: 19329177 | Fulltext

Rationale, design, and governance of Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen Or Naproxen (PRECISION), a cardiovascular end point trial of nonsteroidal antiinflammatory agents in patients with arthritis.

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Becker MC, Wang TH, Wisniewski L, Wolski K, Libby P, Lüscher TF, Borer JS, Mascette AM, Husni ME, Solomon DH, Graham DY, Yeomans ND, Krum H, Ruschitzka F, Lincoff AM, Nissen SE,

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American heart journal 157(4):606-12, 2009 Apr - Who cited this? | PubMed ID: 19332185 | Fulltext

Molecular and cellular mechanisms of the thrombotic complications of atherosclerosis.

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Libby P

Journal of lipid research 50 Suppl:S352-7, 2009 Apr - Who cited this? | PubMed ID: 19096046 | Fulltext

Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II.

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Deguchi JO, Huang H, Libby P, Aikawa E, Whittaker P, Sylvan J, Lee RT, and Aikawa M

Laboratory investigation; a journal of technical methods and pathology 89(3):315-26, 2009 Mar - Who cited this? | PubMed ID: 19153555 | Fulltext

Free Cholesterol Accumulation in Macrophage Membranes Activates Toll-Like Receptors and p38 Mitogen-Activated Protein Kinase and Induces Cathepsin K.

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Sun Y, Ishibashi M, Seimon T, Lee M, Sharma SM, Fitzgerald KA, Samokhin AO, Wang Y, Sayers S, Aikawa M, Jerome WG, Ostrowski MC, Bromme D, Libby P, Tabas IA, Welch CL,

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Circulation research 104(4):455-65, 2009 Feb 27 - Who cited this? | PubMed ID: 19122179 | Fulltext

T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice.

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Ovchinnikova O, Robertson AK, Wågsäter D, Folco EJ, Hyry M, Myllyharju J, Eriksson P, Libby P, and Hansson GK

The American journal of pathology 174(2):693-700, 2009 Feb - Who cited this? | PubMed ID: 19131590 | Fulltext

Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors.

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Wildgruber M, Lee H, Chudnovskiy A, Yoon TJ, Etzrodt M, Pittet MJ, Nahrendorf M, Croce K, Libby P, Weissleder R, and Swirski FK

PLoS ONE 4(5):e5663, 2009 - Who cited this? | PubMed ID: 19440313 | Fulltext

Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors.

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Wildgruber M, Lee H, Chudnovskiy A, Yoon TJ, Etzrodt M, Pittet MJ, Nahrendorf M, Croce K, Libby P, Weissleder R, and Swirski FK

PLoS ONE 4(5):e5663, 2009 - Who cited this? | PubMed ID: 19461894 | Fulltext

Toll-Like Receptor 2 Mediates Apolipoprotein CIII-Induced Monocyte Activation.

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Kawakami A, Osaka M, Aikawa M, Uematsu S, Akira S, Libby P, Shimokado K, Sacks FM, and Yoshida M

Circulation research 103(12):1402-9, 2008 Dec 5 - Who cited this? | PubMed ID: 18974386 | Fulltext

Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.

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Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ, and JUPITER Study Group

The New England journal of medicine 359(21):2195-207, 2008 Nov 20 - Who cited this? | PubMed ID: 18997196 | Fulltext

Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis.

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Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P, and Weissleder R

Circulation 118(18):1802-9, 2008 Oct 28 - Who cited this? | PubMed ID: 18852366 | Fulltext

CD11c+ Dendritic Cells Maintain Antigen Processing, Presentation Capabilities, and CD4+ T-Cell Priming Efficacy Under Hypercholesterolemic Conditions Associated With Atherosclerosis.

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Packard RR, Maganto-García E, Gotsman I, Tabas I, Libby P, and Lichtman AH

Circulation research 103(9):965-73, 2008 Oct 24 - Who cited this? | PubMed ID: 18832748 | Fulltext

The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models.

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Weber C, Zernecke A, and Libby P

Nature reviews. Immunology 8(10):802-15, 2008 Oct - Who cited this? | PubMed ID: 18825131 | Fulltext

Role of inflammation in atherosclerosis associated with rheumatoid arthritis.

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Libby P

The American journal of medicine 121(10 Suppl 1):S21-31, 2008 Oct - Who cited this? | PubMed ID: 18926166 | Fulltext

Interferon-{gamma}, a Th1 Cytokine, Regulates Fat Inflammation. A Role for Adaptive Immunity in Obesity.

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Rocha VZ, Folco EJ, Sukhova G, Shimizu K, Gotsman I, Vernon AH, and Libby P

Circulation research, 2008 Jul 24 - Who cited this? | PubMed ID: 18658050 | Fulltext

Diversity of denizens of the atherosclerotic plaque: not all monocytes are created equal.

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Libby P, Nahrendorf M, Pittet MJ, and Swirski FK

Circulation 117(25):3168, 2008 Jun 24 - Who cited this? | PubMed ID: 18574058 | Fulltext

Genetically programmed biases in Th1 and th2 immune responses modulate atherogenesis.

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Schulte S, Sukhova GK, and Libby P

The American journal of pathology 172(6):1500, 2008 Jun - Who cited this? | PubMed ID: 18467709 | Fulltext

Glycated LDL increases monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated chemotaxis.

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Isoda K, Folco E, Marwali MR, Ohsuzu F, and Libby P

Atherosclerosis 198(2):307-12, 2008 Jun - Who cited this? | PubMed ID: 18164016 | Fulltext

The molecular mechanisms of the thrombotic complications of atherosclerosis.

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Libby P

Journal of internal medicine 263(5):517, 2008 May - Who cited this? | PubMed ID: 18410595 | Fulltext

Leukocyte integrin Mac-1 promotes acute cardiac allograft rejection.

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Shimizu K, Libby P, Shubiki R, Sakuma M, Wang Y, Asano K, Mitchell RN, and Simon DI

Circulation 117(15):1997-2008, 2008 Apr 15 - Who cited this? | PubMed ID: 18378617 | Fulltext

Prostaglandin E Receptor Type 4-associated Protein Interacts Directly with NF-{kappa}B1 and Attenuates Macrophage Activation.

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Minami M, Shimizu K, Okamoto Y, Folco E, Ilasaca ML, Feinberg MW, Aikawa M, and Libby P

The Journal of biological chemistry 283(15):9692-703, 2008 Apr 11 - Who cited this? | PubMed ID: 18270204 | Fulltext

Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury.

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Nahrendorf M, Sosnovik D, Chen JW, Panizzi P, Figueiredo JL, Aikawa E, Libby P, Swirski FK, and Weissleder R

Circulation 117(9):1153, 2008 Mar 4 - Who cited this? | PubMed ID: 18268141 | Fulltext

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