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Papers authored by Leclercq I

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Development of hepatic fibrosis occurs normally in AMPK-deficient mice.

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Da Silva Morais A, Abarca-Quinones J, Guigas B, Viollet B, Stärkel P, Horsmans Y, and Leclercq IA

Clinical science (London, England : 1979) 118(6):411-20, 2010 Mar - Who cited this? | PubMed ID: 19852755 | Fulltext

Clodronate liposomes: All sites of injection are not equal.

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Lanthier N, Horsmans Y, and Leclercq IA

Hepatology (Baltimore, Md.) 51(2):721-2, 2010 Feb - Who cited this? | PubMed ID: 20101758 | Fulltext

Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats.

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Borbath I, Leclercq IA, Sempoux C, Abarca-Quinones J, Desaeger C, and Horsmans Y

Chemico-biological interactions 183(1):238-48, 2010 Jan 5 - Who cited this? | PubMed ID: 19874807 | Fulltext

High-density resequencing DNA microarrays in public health emergencies.

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Berthet N, Leclercq I, Dublineau A, Shigematsu S, Burguière AM, Filippone C, Gessain A, and Manuguerra JC

Nature biotechnology 28(1):25-7, 2010 Jan - Who cited this? | PubMed ID: 20062034 | Fulltext

Adiponectin in non-alcoholic steatohepatitis: an ideal culprit, but what are the proofs of its guilt?.

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Lanthier N and Leclercq IA

Journal of gastroenterology and hepatology 24(10):1584-6, 2009 Oct - Who cited this? | PubMed ID: 19788599 | Fulltext

Early detection of steatohepatitis in fatty rat liver by using MR elastography.

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Salameh N, Larrat B, Abarca-Quinones J, Pallu S, Dorvillius M, Leclercq I, Fink M, Sinkus R, and Van Beers BE

Radiology 253(1):90-7, 2009 Oct - Who cited this? | PubMed ID: 19587308 | Fulltext

Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis.

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Phung N, Pera N, Farrell G, Leclercq I, Hou JY, and George J

International journal of molecular medicine 24(2):171-80, 2009 Aug - Who cited this? | PubMed ID: 19578790 | Fulltext

Kupffer cells mediate leptin-induced liver fibrosis.

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Wang J, Leclercq I, Brymora JM, Xu N, Ramezani-Moghadam M, London RM, Brigstock D, and George J

Gastroenterology 137(2):713-723.e1, 2009 Aug - Who cited this? | PubMed ID: 19375424 | Fulltext

The metabolic syndrome: how it may influence hepatic stellate cell activation and hepatic fibrosis.

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Lanthier N, Horsmans Y, and Leclercq IA

Current opinion in clinical nutrition and metabolic care 12(4):404-11, 2009 Jul - Who cited this? | PubMed ID: 19474722 | Fulltext

The Ras inhibitor farnesylthiosalicyclic acid (FTS) prevents nodule formation and development of preneoplastic foci of altered hepatocytes in rats.

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Schneider-Merck T, Borbath I, Charette N, De Saeger C, Abarca J, Leclercq I, Horsmans Y, and Stärkel P

European journal of cancer (Oxford, England : 1990) 45(11):2050-60, 2009 Jul - Who cited this? | PubMed ID: 19427195 | Fulltext

Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.

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Van Hul NK, Abarca-Quinones J, Sempoux C, Horsmans Y, and Leclercq IA

Hepatology (Baltimore, Md.) 49(5):1625-35, 2009 May - Who cited this? | PubMed ID: 19296469 | Fulltext

Prevention of steatohepatitis by pioglitazone: Implication of adiponectin-dependent inhibition of SREBP-1c and inflammation.

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Da Silva Morais A, Lebrun V, Abarca-Quinones J, Brichard S, Hue L, Guigas B, Viollet B, and Leclercq IA

Journal of hepatology 50(3):489-500, 2009 Mar - Who cited this? | PubMed ID: 19155087 | Fulltext

DUX4c Is Up-Regulated in FSHD. It Induces the MYF5 Protein and Human Myoblast Proliferation.

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Ansseau E, Laoudj-Chenivesse D, Marcowycz A, Tassin A, Vanderplanck C, Sauvage S, Barro M, Mahieu I, Leroy A, Leclercq I, Mainfroid V, Figlewicz D, Mouly V, Butler-Browne G, Belayew A, and Coppée F

PLoS ONE 4(10):e7482, 2009 - Who cited this? | PubMed ID: 19829708 | Fulltext

Nonalcoholic fatty liver disease: the potential role of nutritional management.

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Leclercq IA and Horsmans Y

Current opinion in clinical nutrition and metabolic care 11(6):766-73, 2008 Nov - Who cited this? | PubMed ID: 18827582 | Fulltext

Phi29 polymerase based random amplification of viral RNA as an alternative to random RT-PCR.

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Berthet N, Reinhardt AK, Leclercq I, van Ooyen S, Batejat C, Dickinson P, Stamboliyska R, Old IG, Kong KA, Dacheux L, Bourhy H, Kennedy GC, Korfhage C, Cole ST, and Manuguerra JC

BMC molecular biology 9(1):77, 2008 Sep 4 - Who cited this? | PubMed ID: 18771595 | Fulltext

Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats.

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da Silva Morais A, Saliez A, Leclercq I, Horsmans Y, and Stärkel P

Clinical science (London, England : 1979) 114(1):73-83, 2008 Jan - Who cited this? | PubMed ID: 17678500 | Fulltext

Severe acute cholestatic hepatitis with prolonged cholestasis and bile-duct injury following atorvastatin therapy: a case report.

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Rahier JF, Rahier J, Leclercq I, and Geubel AP

Acta gastro-enterologica Belgica 71(3):318-20, 2008 - Who cited this? | PubMed ID: 19198578 | Fulltext

Inhibition of early preneoplastic events in the rat liver by the somatostatin analog lanreotide.

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Borbath I, Leclercq IA, Abarca-Quinones J, Desaeger C, Lebrun V, Moulin P, Sempoux C, and Horsmans Y

Cancer science 98(12):1831-9, 2007 Dec - Who cited this? | PubMed ID: 17900309 | Fulltext

ADAM metallopeptidase with thrombospondin type 1 motif 2 inactivation reduces the extent and stability of carbon tetrachloride-induced hepatic fibrosis in mice.

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Kesteloot F, Desmoulière A, Leclercq I, Thiry M, Arrese JE, Prockop DJ, Lapière CM, Nusgens BV, and Colige A

Hepatology (Baltimore, Md.) 46(5):1620-31, 2007 Nov - Who cited this? | PubMed ID: 17929299 | Fulltext

Hepatic viscoelastic parameters measured with MR elastography: correlations with quantitative analysis of liver fibrosis in the rat.

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Salameh N, Peeters F, Sinkus R, Abarca-Quinones J, Annet L, Ter Beek LC, Leclercq I, and Van Beers BE

Journal of magnetic resonance imaging : JMRI 26(4):956-62, 2007 Oct - Who cited this? | PubMed ID: 17896384 | Fulltext

Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences.

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Leclercq IA, Da Silva Morais A, Schroyen B, Van Hul N, and Geerts A

Journal of hepatology 47(1):142-56, 2007 Jul - Who cited this? | PubMed ID: 17512085 | Fulltext

Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis.

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González-Ramos R, Donnez J, Defrère S, Leclercq I, Squifflet J, Lousse JC, and Van Langendonckt A

Molecular human reproduction 13(7):503-9, 2007 Jul - Who cited this? | PubMed ID: 17483545 | Fulltext

The PPARgamma agonist pioglitazone inhibits early neoplastic occurrence in the rat liver.

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Borbath I, Leclercq I, Moulin P, Sempoux C, and Horsmans Y

European journal of cancer (Oxford, England : 1990) 43(11):1755-63, 2007 Jul - Who cited this? | PubMed ID: 17582756 | Fulltext

NADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis.

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dela Peña A, Leclercq IA, Williams J, and Farrell GC

Journal of hepatology 46(2):304-13, 2007 Feb - Who cited this? | PubMed ID: 17157947 | Fulltext

Role of signal transducer and activator of transcription 3 in liver fibrosis progression in chronic hepatitis C-infected patients.

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Stärkel P, Saeger CD, Leclercq I, and Horsmans Y

Laboratory investigation; a journal of technical methods and pathology 87(2):173-81, 2007 Feb - Who cited this? | PubMed ID: 17318196 | Fulltext

Peroxisome proliferated-activated receptor gamma ligand, Pioglitazone, does not prevent hepatic fibrosis in mice.

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Da Silva Morais A, Abarca-Quinones J, Horsmans Y, Stärkel P, and Leclercq IA

International journal of molecular medicine 19(1):105-12, 2007 Jan - Who cited this? | PubMed ID: 17143554 | Fulltext

Intrahepatic insulin resistance in a murine model of steatohepatitis: effect of PPARgamma agonist pioglitazone.

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Leclercq IA, Lebrun VA, Stärkel P, and Horsmans YJ

Laboratory investigation; a journal of technical methods and pathology 87(1):56-65, 2007 Jan - Who cited this? | PubMed ID: 17075577 | Fulltext

Assessment of diffusion-weighted MR imaging in liver fibrosis.

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Annet L, Peeters F, Abarca-Quinones J, Leclercq I, Moulin P, and Van Beers BE

Journal of magnetic resonance imaging : JMRI 25(1):122-8, 2007 Jan - Who cited this? | PubMed ID: 17154179 | Fulltext

Codon conservation in the influenza A virus genome defines RNA packaging signals.

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Gog JR, Afonso Edos S, Dalton RM, Leclercq I, Tiley L, Elton D, von Kirchbach JC, Naffakh N, Escriou N, and Digard P

Nucleic acids research 35(6):1897-907, 2007 - Who cited this? | PubMed ID: 17332012 | Fulltext

Pathogenesis of steatohepatitis: insights from the study of animal models.

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Leclercq IA

Acta gastro-enterologica Belgica 70(1):25-31, 2007 - Who cited this? | PubMed ID: 17619535 | Fulltext

Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin.

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Leclercq IA, Vansteenberghe M, Lebrun VB, VanHul NK, Abarca-Quinones J, Sempoux CL, Picard C, Stärkel P, and Horsmans YL

Laboratory investigation; a journal of technical methods and pathology 86(11):1161-71, 2006 Nov - Who cited this? | PubMed ID: 16983330 | Fulltext

Limited therapeutic efficacy of pioglitazone on progression of hepatic fibrosis in rats.

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Leclercq IA, Sempoux C, Stärkel P, and Horsmans Y

Gut 55(7):1020-9, 2006 Jul - Who cited this? | PubMed ID: 16484506 | Fulltext

COX-2 induction in mice with experimental nutritional steatohepatitis: Role as pro-inflammatory mediator.

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Yu J, Ip E, Dela Peña A, Hou JY, Sesha J, Pera N, Hall P, Kirsch R, Leclercq I, and Farrell GC

Hepatology (Baltimore, Md.) 43(4):826-36, 2006 Apr - Who cited this? | PubMed ID: 16557554 | Fulltext

Hypervitaminosis A-induced liver fibrosis: stellate cell activation and daily dose consumption.

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Nollevaux MC, Guiot Y, Horsmans Y, Leclercq I, Rahier J, Geubel AP, and Sempoux C

Liver international : official journal of the International Association for the Study of the Liver 26(2):182-6, 2006 Mar - Who cited this? | PubMed ID: 16448456 | Fulltext

Disrupted NF- kappa B activation after partial hepatectomy does not impair hepatocyte proliferation in rats.

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Laurent S, Horsmans Y, Stärkel P, Leclercq I, Sempoux C, and Lambotte L

World journal of gastroenterology : WJG 11(46):7345, 2005 Dec 14 - Who cited this? | PubMed ID: 16437640 | Fulltext

NF-kappaB activation, rather than TNF, mediates hepatic inflammation in a murine dietary model of steatohepatitis.

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Dela Peña A, Leclercq I, Field J, George J, Jones B, and Farrell G

Gastroenterology 129(5):1663-74, 2005 Nov - Who cited this? | PubMed ID: 16285964 | Fulltext

The generation of recombinant influenza A viruses expressing a PB2 fusion protein requires the conservation of a packaging signal overlapping the coding and noncoding regions at the 5' end of the PB2 segment.

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Dos Santos Afonso E, Escriou N, Leclercq I, van der Werf S, and Naffakh N

Virology 341(1):34-46, 2005 Oct 10 - Who cited this? | PubMed ID: 16084555 | Fulltext

Deficient Stat3 DNA-binding is associated with high Pias3 expression and a positive anti-apoptotic balance in human end-stage alcoholic and hepatitis C cirrhosis.

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Stärkel P, De Saeger C, Leclercq I, Strain A, and Horsmans Y

Journal of hepatology 43(4):687-95, 2005 Oct - Who cited this? | PubMed ID: 16098628 | Fulltext

Impaired inhibition of NF-kappaB activity by melanoma-associated p16INK4a mutations.

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Becker TM, Rizos H, de la Pena A, Leclercq IA, Woodruff S, Kefford RF, and Mann GJ

Biochemical and biophysical research communications 332(3):873-9, 2005 Jul 8 - Who cited this? | PubMed ID: 15913553 | Fulltext

Blunted DNA synthesis and delayed S-phase entry following inhibition of Cdk2 activity in the regenerating rat liver.

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Stärkel P, De Saeger C, Sempoux C, Legrand E, Leclercq I, and Horsmans Y

Laboratory investigation; a journal of technical methods and pathology 85(4):562-71, 2005 Apr - Who cited this? | PubMed ID: 15696186 | Fulltext

Molecular events associated with accelerated proliferative response in rat livers when partial hepatectomy is preceded by a sham operation.

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Laurent S, Stärkel P, Leclercq IA, Lambotte L, Maiter D, and Horsmans Y

European journal of clinical investigation 35(2):140-7, 2005 Feb - Who cited this? | PubMed ID: 15667586 | Fulltext

The role of pro- and anti-inflammatory responses in silica-induced lung fibrosis.

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Barbarin V, Nihoul A, Misson P, Arras M, Delos M, Leclercq I, Lison D, and Huaux F

Respiratory research 6:112, 2005 - Who cited this? | PubMed ID: 16212659 | Fulltext

Curcumin inhibits NF-kappaB activation and reduces the severity of experimental steatohepatitis in mice.

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Leclercq IA, Farrell GC, Sempoux C, dela Peña A, and Horsmans Y

Journal of hepatology 41(6):926-34, 2004 Dec - Who cited this? | PubMed ID: 15582125 | Fulltext

Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice.

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Ip E, Farrell G, Hall P, Robertson G, and Leclercq I

Hepatology (Baltimore, Md.) 39(5):1286-96, 2004 May - Who cited this? | PubMed ID: 15122757 | Fulltext

Antioxidant defence mechanisms: new players in the pathogenesis of non-alcoholic steatohepatitis?.

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Leclercq IA

Clinical science (London, England : 1979) 106(3):235-7, 2004 Mar - Who cited this? | PubMed ID: 14604432 | Fulltext

Lipid peroxidation, stellate cell activation and hepatic fibrogenesis in a rat model of chronic steatohepatitis.

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George J, Pera N, Phung N, Leclercq I, Yun Hou J, and Farrell G

Journal of hepatology 39(5):756-64, 2003 Nov - Who cited this? | PubMed ID: 14568258 | Fulltext

Oxidative stress, KLF6 and transforming growth factor-beta up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats.

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Stärkel P, Sempoux C, Leclercq I, Herin M, Deby C, Desager JP, and Horsmans Y

Journal of hepatology 39(4):538-46, 2003 Oct - Who cited this? | PubMed ID: 12971963 | Fulltext

Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice.

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Ip E, Farrell GC, Robertson G, Hall P, Kirsch R, and Leclercq I

Hepatology (Baltimore, Md.) 38(1):123-32, 2003 Jul - Who cited this? | PubMed ID: 12829994 | Fulltext

Naturally occurring substitutions of the human T-cell leukemia virus type 1 3' LTR influence strand-transfer reaction.

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Leclercq I, Mortreux F, Rabaaoui S, Jonsson CB, and Wattel E

Journal of virological methods 109(2):105-17, 2003 May - Who cited this? | PubMed ID: 12711052 | Fulltext

Leptin-specific mechanisms for impaired liver regeneration in ob/ob mice after toxic injury.

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Leclercq IA, Field J, and Farrell GC

Gastroenterology 124(5):1451-64, 2003 May - Who cited this? | PubMed ID: 12730884 | Fulltext

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