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Papers authored by Le Couteur DG

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Drug Burden Index and physical function in older Australian men.

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Gnjidic D, Cumming RG, Le Couteur DG, Handelsman DJ, Naganathan V, Abernethy DR, and Hilmer SN

British journal of clinical pharmacology 68(1):97-105, 2009 Jul - Who cited this? | PubMed ID: 19660007 | Fulltext

Do medical courses adequately prepare interns for safe and effective prescribing in New South Wales public hospitals?.

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Hilmer SN, Seale JP, Le Couteur DG, Crampton R, and Liddle C

Internal medicine journal 39(7):428-34, 2009 Jul - Who cited this? | PubMed ID: 19383059 | Fulltext

Variability in response to medicines in older people: phenotypic and genotypic factors.

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McLachlan AJ, Hilmer SN, and Le Couteur DG

Clinical pharmacology and therapeutics 85(4):431-3, 2009 Apr - Who cited this? | PubMed ID: 19225449 | Fulltext

Liver sinusoidal endothelial cells and acute non-oxidative hepatic injury induced by Pseudomonas aeruginosa pyocyanin.

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Cheluvappa R, Cogger VC, Kwun SY, O'Reilly JN, Le Couteur DG, and Hilmer SN

International journal of experimental pathology 89(6):410-8, 2008 Dec - Who cited this? | PubMed ID: 19134050 | Fulltext

Pain, frailty and comorbidity on older men: the CHAMP study.

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Blyth FM, Rochat S, Cumming RG, Creasey H, Handelsman DJ, Le Couteur DG, Naganathan V, Sambrook PN, Seibel MJ, and Waite LM

Pain 140(1):224-30, 2008 Nov 15 - Who cited this? | PubMed ID: 18835100 | Fulltext

Reactions of Pseudomonas aeruginosa pyocyanin with reduced glutathione.

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Cheluvappa R, Shimmon R, Dawson M, Hilmer SN, and Le Couteur DG

Acta biochimica Polonica, 2008 Sep 17 - Who cited this? | PubMed ID: 18797520 | Fulltext

Old age and the hepatic sinusoid.

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Le Couteur DG, Warren A, Cogger VC, Smedsrød B, Sørensen KK, De Cabo R, Fraser R, and McCuskey RS

Anatomical record (Hoboken, N.J. : 2007) 291(6):672-83, 2008 Jun - Who cited this? | PubMed ID: 18484614 | Fulltext

Pharmaco-epistemology for the prescribing geriatrician.

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Le Couteur DG and Kendig H

Australasian journal on ageing 27(1):3-7, 2008 Mar - Who cited this? | PubMed ID: 18713208 | Fulltext

Effects of old age on vascular complexity and dispersion of the hepatic sinusoidal network.

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Warren A, Chaberek S, Ostrowski K, Cogger VC, Hilmer SN, McCuskey RS, Fraser R, and Le Couteur DG

Microcirculation (New York, N.Y. : 1994) 15(3):191-202, 2008 - Who cited this? | PubMed ID: 18386215 | Fulltext

The influence of oxygen tension on the structure and function of isolated liver sinusoidal endothelial cells.

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Martinez I, Nedredal GI, Oie CI, Warren A, Johansen O, Le Couteur DG, and Smedsrød B

Comparative hepatology 7:4, 2008 - Who cited this? | PubMed ID: 18457588 | Fulltext

Medication withdrawal trials in people aged 65 years and older : a systematic review.

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Iyer S, Naganathan V, McLachlan AJ, and Le Couteur DG

Drugs & aging 25(12):1021-31, 2008 - Who cited this? | PubMed ID: 19021301 | Fulltext

The effect of old age on liver oxygenation and the hepatic expression of VEGF and VEGFR2.

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Cheluvappa R, Hilmer SN, Kwun SY, Jamieson HA, O'Reilly JN, Muller M, Cogger VC, and Le Couteur DG

Experimental gerontology 42(10):1012-9, 2007 Oct - Who cited this? | PubMed ID: 17658234 | Fulltext

Effects of old age on hepatocyte oxygenation.

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Cheluvappa R, Hilmer SN, Kwun SY, Cogger VC, and LE Couteur DG

Annals of the New York Academy of Sciences 1114:88-92, 2007 Oct - Who cited this? | PubMed ID: 17717093 | Fulltext

Life extension by calorie restriction in humans.

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Everitt AV and Le Couteur DG

Annals of the New York Academy of Sciences 1114:428-33, 2007 Oct - Who cited this? | PubMed ID: 17717102 | Fulltext

Age-related changes in the liver sinusoidal endothelium: a mechanism for dyslipidemia.

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LE Couteur DG, Cogger VC, McCuskey RS, DE Cabo R, Smedsrød B, Sorensen KK, Warren A, and Fraser R

Annals of the New York Academy of Sciences 1114:79-87, 2007 Oct - Who cited this? | PubMed ID: 17804522 | Fulltext

Basal activity of Kupffer cells increases with old age.

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Hilmer SN, Cogger VC, and Le Couteur DG

The journals of gerontology. Series A, Biological sciences and medical sciences 62(9):973-8, 2007 Sep - Who cited this? | PubMed ID: 17895435 | Fulltext

Alterations in liver sinusoidal endothelium in a baboon model of type 1 diabetes.

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Jamieson HA, Cogger VC, Twigg SM, McLennan SV, Warren A, Cheluvappa R, Hilmer SN, Fraser R, de Cabo R, and Le Couteur DG

Diabetologia 50(9):1969-76, 2007 Sep - Who cited this? | PubMed ID: 17604976 | Fulltext

The effect of Pseudomonas aeruginosa virulence factor, pyocyanin, on the liver sinusoidal endothelial cell.

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Cheluvappa R, Jamieson HA, Hilmer SN, Muller M, and Le Couteur DG

Journal of gastroenterology and hepatology 22(8):1350, 2007 Aug - Who cited this? | PubMed ID: 17688676 | Fulltext

Clinical pharmacology in the geriatric patient.

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Hilmer SN, McLachlan AJ, and Le Couteur DG

Fundamental & clinical pharmacology 21(3):217-30, 2007 Jun - Who cited this? | PubMed ID: 17521291 | Fulltext

Caloric restriction reduces age-related pseudocapillarization of the hepatic sinusoid.

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Jamieson HA, Hilmer SN, Cogger VC, Warren A, Cheluvappa R, Abernethy DR, Everitt AV, Fraser R, de Cabo R, and Le Couteur DG

Experimental gerontology 42(4):374-8, 2007 Apr - Who cited this? | PubMed ID: 17204388 | Fulltext

Marked changes of the hepatic sinusoid in a transgenic mouse model of acute immune-mediated hepatitis.

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Warren A, Bertolino P, Benseler V, Fraser R, McCaughan GW, and Le Couteur DG

Journal of hepatology 46(2):239-46, 2007 Feb - Who cited this? | PubMed ID: 17125874 | Fulltext

Sleep disturbances and falls in older people.

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Latimer Hill E, Cumming RG, Lewis R, Carrington S, and Le Couteur DG

The journals of gerontology. Series A, Biological sciences and medical sciences 62(1):62-6, 2007 Jan - Who cited this? | PubMed ID: 17301039 | Fulltext

Hyperlipidemia and surfactants: the liver sieve is a link.

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Cogger VC, Hilmer SN, Sullivan D, Muller M, Fraser R, and Le Couteur DG

Atherosclerosis 189(2):273-81, 2006 Dec - Who cited this? | PubMed ID: 16458315 | Fulltext

T lymphocytes interact with hepatocytes through fenestrations in murine liver sinusoidal endothelial cells.

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Warren A, Le Couteur DG, Fraser R, Bowen DG, McCaughan GW, and Bertolino P

Hepatology (Baltimore, Md.) 44(5):1182-90, 2006 Nov - Who cited this? | PubMed ID: 17058232 | Fulltext

Beta-blockers and heart failure in older people.

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Le Couteur DG, Bailey L, and Naganathan V

European heart journal 27(7):887-8; author reply 888-9, 2006 Apr - Who cited this? | PubMed ID: 16478748 | Fulltext

Dietary approaches that delay age-related diseases.

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Everitt AV, Hilmer SN, Brand-Miller JC, Jamieson HA, Truswell AS, Sharma AP, Mason RS, Morris BJ, and Le Couteur DG

Clinical interventions in aging 1(1):11-31, 2006 - Who cited this? | PubMed ID: 18047254 | Fulltext

Age-related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat.

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Hilmer SN, Cogger VC, Fraser R, McLean AJ, Sullivan D, and Le Couteur DG

Hepatology (Baltimore, Md.) 42(6):1349-54, 2005 Dec - Who cited this? | PubMed ID: 16317689 | Fulltext

Hepatic pseudocapillarization in aged mice.

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Warren A, Bertolino P, Cogger VC, McLean AJ, Fraser R, and Le Couteur DG

Experimental gerontology 40(10):807-12, 2005 Oct - Who cited this? | PubMed ID: 16125353 | Fulltext

The C-caffeine breath test distinguishes significant fibrosis in chronic hepatitis B and reflects response to lamivudine therapy.

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Park GJ, Katelaris PH, Jones DB, Seow F, Lin BP, Le Couteur DG, and Ngu MC

Alimentary pharmacology & therapeutics 22(5):395, 2005 Sep 1 - Who cited this? | PubMed ID: 16128677 | Fulltext

A randomized clinical trial of activated charcoal for the routine management of oral drug overdose.

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Cooper GM, Le Couteur DG, Richardson D, and Buckley NA

QJM : monthly journal of the Association of Physicians 98(9):655-60, 2005 Sep - Who cited this? | PubMed ID: 16040667 | Fulltext

Atypical antipsychotic medications and risk of falls in residents of aged care facilities.

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Hien le TT, Cumming RG, Cameron ID, Chen JS, Lord SR, March LM, Schwarz J, Le Couteur DG, and Sambrook PN

Journal of the American Geriatrics Society 53(8):1290-5, 2005 Aug - Who cited this? | PubMed ID: 16078953 | Fulltext

Clinical implications of changes in hepatic drug metabolism in older people.

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Hilmer SN, Shenfield GM, and Le Couteur DG

Therapeutics and clinical risk management 1(2):151, 2005 Jun - Who cited this? | PubMed ID: 18360554 | Fulltext

Progressive familial intrahepatic cholestasis: genetic disorders of biliary transporters.

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Harris MJ, Le Couteur DG, and Arias IM

Journal of gastroenterology and hepatology 20(6):807-17, 2005 Jun - Who cited this? | PubMed ID: 15946126 | Fulltext

The effect of meals at different mealtimes on blood pressure and symptoms in geriatric patients with postprandial hypotension.

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Fisher AA, Davis MW, and Le Couteur DG

The journals of gerontology. Series A, Biological sciences and medical sciences 60(2):184-5; author reply 185-6, 2005 Feb - Who cited this? | PubMed ID: 15814859 | Fulltext

The hepatic sinusoid in aging and cirrhosis: effects on hepatic substrate disposition and drug clearance.

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Le Couteur DG, Fraser R, Hilmer S, Rivory LP, and McLean AJ

Clinical pharmacokinetics 44(2):187-200, 2005 - Who cited this? | PubMed ID: 15656697 | Fulltext

Development of a mentorship programme for rural general practitioners by visiting specialist physicians.

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Graffen M, Saligari M, Le Couteur DG, Naganathan V, and McLean A

Rural and remote health 5(2):374, 2005 - Who cited this? | PubMed ID: 15971965 | Fulltext

Prescribing in older people.

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Le Couteur DG, Hilmer SN, Glasgow N, Naganathan V, and Cumming RG

Australian family physician 33(10):777-81, 2004 Oct - Who cited this? | PubMed ID: 15532150 | Fulltext

The effects of oxidative stress on the liver sieve.

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Cogger VC, Muller M, Fraser R, McLean AJ, Khan J, and Le Couteur DG

Journal of hepatology 41(3):370-6, 2004 Sep - Who cited this? | PubMed ID: 15336438 | Fulltext

The hepatic pharmacokinetics of doxorubicin and liposomal doxorubicin.

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Hilmer SN, Cogger VC, Muller M, and Le Couteur DG

Drug metabolism and disposition: the biological fate of chemicals 32(8):794-9, 2004 Aug - Who cited this? | PubMed ID: 15258103 | Fulltext

Wash-in methodology and modeling to determine hepatocellular D-glucose transport in the perfused rat liver.

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Le Couteur DG, Yin ZL, McLean AJ, and Rivory LP

The Japanese journal of physiology 54(4):421-9, 2004 Aug - Who cited this? | PubMed ID: 15631698 | Fulltext

Aging biology and geriatric clinical pharmacology.

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McLean AJ and Le Couteur DG

Pharmacological reviews 56(2):163-84, 2004 Jun - Who cited this? | PubMed ID: 15169926 | Fulltext

Glutathione transferase Omega class polymorphisms in Parkinson disease.

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Whitbread AK, Mellick GD, Silburn PA, Le Couteur DG, and Board PG

Neurology 62(10):1910-1, 2004 May 25 - Who cited this? | PubMed ID: 15159516 | Fulltext

The Vascular Implications of Post-prandial Lipoprotein Metabolism.

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Sullivan DR, Celermajer DS, Le Couteur DG, and Lam CW

The Clinical biochemist. Reviews / Australian Association of Clinical Biochemists 25(1):19-30, 2004 Feb - Who cited this? | PubMed ID: 18516208 | Fulltext

The effect of aging on the immunohistochemistry of apolipoprotein E in the liver.

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Hilmer SN, Warren A, Cogger VC, Fraser R, McLean AJ, Sullivan D, and Le Couteur DG

Experimental gerontology 39(1):53-7, 2004 Jan - Who cited this? | PubMed ID: 14724064 | Fulltext

Validity of the 13C-caffeine breath test as a noninvasive, quantitative test of liver function.

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Park GJ, Katelaris PH, Jones DB, Seow F, Le Couteur DG, and Ngu MC

Hepatology (Baltimore, Md.) 38(5):1227-36, 2003 Nov - Who cited this? | PubMed ID: 14578861 | Fulltext

Hepatic sinusoidal pseudocapillarization with aging in the non-human primate.

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Cogger VC, Warren A, Fraser R, Ngu M, McLean AJ, and Le Couteur DG

Experimental gerontology 38(10):1101-7, 2003 Oct - Who cited this? | PubMed ID: 14580863 | Fulltext

Antimycin A-induced defenestration in rat hepatic sinusoidal endothelial cells.

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Braet F, Muller M, Vekemans K, Wisse E, and Le Couteur DG

Hepatology (Baltimore, Md.) 38(2):394-402, 2003 Aug - Who cited this? | PubMed ID: 12883483 | Fulltext

Liver dysfunction and heart failure.

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Cogger VC, Fraser R, and Le Couteur DG

The American journal of cardiology 91(11):1399, 2003 Jun 1 - Who cited this? | PubMed ID: 12767448 | Fulltext

Age-related pseudocapillarization of the human liver.

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McLean AJ, Cogger VC, Chong GC, Warren A, Markus AM, Dahlstrom JE, and Le Couteur DG

The Journal of pathology 200(1):112-7, 2003 May - Who cited this? | PubMed ID: 12692849 | Fulltext

The liver sieve and gene therapy.

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Fraser R, Le Couteur DG, Warren A, Cogger VC, Bertolino P, and Smith M

Blood 101(8):3338; author reply 3338-9, 2003 Apr 15 - Who cited this? | PubMed ID: 12672697 | Fulltext

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