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Papers authored by Lakey JR

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Pancreatic duct: A suitable route to oxygenate tissue during pancreas hypothermic preservation?.

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Mirbolooki MR, Alexander M, Hoyt DB, and Lakey JR

Transplant immunology 22(3-4):191-4, 2010 Feb - Who cited this? | PubMed ID: 19900551 | Fulltext

Pulsatile intravenous insulin therapy: the best practice to reverse diabetes complications?.

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Reza Mirbolooki M, Taylor GE, Knutzen VK, Scharp DW, Willcourt R, and Lakey JR

Medical hypotheses 73(3):363-9, 2009 Sep - Who cited this? | PubMed ID: 19446964 | Fulltext

The use of an approved biodegradable polymer scaffold as a solid support system for improvement of islet engraftment.

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Kin T, O'Neil JJ, Pawlick R, Korbutt GS, Shapiro AM, and Lakey JR

Artificial organs 32(12):990-3, 2008 Dec - Who cited this? | PubMed ID: 19133030 | Fulltext

Ex vivo transcriptional profiling of human pancreatic islets following chronic exposure to monounsaturated fatty acids.

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Bikopoulos G, da Silva Pimenta A, Lee SC, Lakey JR, Der SD, Chan CB, Ceddia RB, B Wheeler M, and Rozakis-Adcock M

The Journal of endocrinology 196(3):455-64, 2008 Mar - Who cited this? | PubMed ID: 18310441 | Fulltext

Combination therapy with glucagon-like peptide-1 and gastrin induces beta-cell neogenesis from pancreatic duct cells in human islets transplanted in immunodeficient diabetic mice.

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Suarez-Pinzon WL, Lakey JR, and Rabinovitch A

Cell transplantation 17(6):631-40, 2008 - Who cited this? | PubMed ID: 18819251 | Fulltext

Enhancing the success of human islet isolation through optimization and characterization of pancreas dissociation enzyme.

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Kin T, Zhai X, Murdoch TB, Salam A, Shapiro AM, and Lakey JR

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 7(5):1233, 2007 May - Who cited this? | PubMed ID: 17359501 | Fulltext

Pretransplant HLA antibodies are associated with reduced graft survival after clinical islet transplantation.

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Campbell PM, Salam A, Ryan EA, Senior P, Paty BW, Bigam D, McCready T, Halpin A, Imes S, Al Saif F, Lakey JR, and Shapiro AM

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 7(5):1242-8, 2007 May - Who cited this? | PubMed ID: 17456201 | Fulltext

Factors influencing the collagenase digestion phase of human islet isolation.

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Kin T, Johnson PR, Shapiro AM, and Lakey JR

Transplantation 83(1):7-12, 2007 Jan 15 - Who cited this? | PubMed ID: 17220782 | Fulltext

Detection of microbial contamination during human islet isolation.

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Kin T, Rosichuk S, Shapiro AM, and Lakey JR

Cell transplantation 16(1):9-13, 2007 - Who cited this? | PubMed ID: 17436850 | Fulltext

Supply of human allograft tissue in Canada.

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Lakey JR, Mirbolooki M, Rogers C, and Mohr J

Cell and tissue banking 8(2):135-50, 2007 - Who cited this? | PubMed ID: 16804647 | Fulltext

Long-term graft function after allogeneic islet transplantation.

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Lakey JR, Kin T, Warnock GL, Shapiro AM, Tsapogas P, Imes S, Korbutt GS, Kneteman NM, Rajotte RV, and Ryan EA

Cell transplantation 16(4):441-6, 2007 - Who cited this? | PubMed ID: 17658134 | Fulltext

Demand for human allograft tissue in Canada.

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Lakey JR, Mirbolooki M, Rogers C, and Mohr J

Cell and tissue banking 8(1):31-42, 2007 - Who cited this? | PubMed ID: 16804648 | Fulltext

Compaction of islets is detrimental to transplant outcome in mice.

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Merani S, Schur C, Truong W, Knutzen VK, Lakey JR, Anderson CC, Ricordi C, and Shapiro AM

Transplantation 82(11):1472-6, 2006 Dec 15 - Who cited this? | PubMed ID: 17164719 | Fulltext

Improved outcomes in islet isolation and transplantation by the use of a novel hemoglobin-based O2 carrier.

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Avila JG, Wang Y, Barbaro B, Gangemi A, Qi M, Kuechle J, Doubleday N, Doubleday M, Churchill T, Salehi P, Shapiro J, Philipson LH, Benedetti E, Lakey JR, and Oberholzer J

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 6(12):2861-70, 2006 Dec - Who cited this? | PubMed ID: 17062000 | Fulltext

Islet isolation and transplantation outcomes of pancreas preserved with University of Wisconsin solution versus two-layer method using preoxygenated perfluorocarbon.

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Kin T, Mirbolooki M, Salehi P, Tsukada M, O'Gorman D, Imes S, Ryan EA, Shapiro AM, and Lakey JR

Transplantation 82(10):1286-90, 2006 Nov 27 - Who cited this? | PubMed ID: 17130776 | Fulltext

Culture medium modulates proinflammatory conditions of human pancreatic islets before transplantation.

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Marzorati S, Antonioli B, Nano R, Maffi P, Piemonti L, Giliola C, Secchi A, Lakey JR, and Bertuzzi F

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 6(11):2791, 2006 Nov - Who cited this? | PubMed ID: 16939517 | Fulltext

Comparison of aortic valve allograft decellularization techniques in the rat.

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Meyer SR, Chiu B, Churchill TA, Zhu L, Lakey JR, and Ross DB

Journal of biomedical materials research. Part A 79(2):254-62, 2006 Nov - Who cited this? | PubMed ID: 16817222 | Fulltext

Development of a novel beta-cell specific promoter system for the identification of insulin-producing cells in in vitro cell cultures.

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Fukazawa T, Matsuoka J, Naomoto Y, Nakai T, Durbin ML, Kojima I, Lakey JR, and Tanaka N

Experimental cell research 312(17):3404-12, 2006 Oct 15 - Who cited this? | PubMed ID: 16934249 | Fulltext

The impact of the mTOR inhibitor sirolimus on the proliferation and function of pancreatic islets and ductal cells.

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Bussiere CT, Lakey JR, Shapiro AM, and Korbutt GS

Diabetologia 49(10):2341-9, 2006 Oct - Who cited this? | PubMed ID: 16896936 | Fulltext

International trial of the Edmonton protocol for islet transplantation.

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Shapiro AM, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, Robertson RP, Secchi A, Brendel MD, Berney T, Brennan DC, Cagliero E, Alejandro R, Ryan EA, DiMercurio B, Morel P, Polonsky KS,

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The New England journal of medicine 355(13):1318, 2006 Sep 28 - Who cited this? | PubMed ID: 17005949 | Fulltext

Pancreatic islet autotransplantation with completion pancreatectomy in the management of uncontrolled pancreatic fistula after whipple resection for ampullary adenocarcinoma.

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Alsaif F, Molinari M, Al-Masloom A, Lakey JR, Kin T, and Shapiro AM

Pancreas 32(4):430-1, 2006 May - Who cited this? | PubMed ID: 16670628 | Fulltext

Assessment of glycemic control after islet transplantation using the continuous glucose monitor in insulin-independent versus insulin-requiring type 1 diabetes subjects.

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Paty BW, Senior PA, Lakey JR, Shapiro AM, and Ryan EA

Diabetes technology & therapeutics 8(2):165-73, 2006 Apr - Who cited this? | PubMed ID: 16734547 | Fulltext

Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas.

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Hao E, Tyrberg B, Itkin-Ansari P, Lakey JR, Geron I, Monosov EZ, Barcova M, Mercola M, and Levine F

Nature medicine 12(3):310-6, 2006 Mar - Who cited this? | PubMed ID: 16491084 | Fulltext

Oxygen and pancreas preservation.

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Mirbolooki M and Lakey JR

Transplantation 81(3):492; author reply 492-3, 2006 Feb 15 - Who cited this? | PubMed ID: 16477245 | Fulltext

Expansion of mesenchymal stem cells from human pancreatic ductal epithelium.

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Seeberger KL, Dufour JM, Shapiro AM, Lakey JR, Rajotte RV, and Korbutt GS

Laboratory investigation; a journal of technical methods and pathology 86(2):141-53, 2006 Feb - Who cited this? | PubMed ID: 16402034 | Fulltext

Comparison of cooling systems during islet purification.

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Swift S, Kin T, Mirbolooki M, Wilson R, and Lakey JR

Cell transplantation 15(2):175-80, 2006 - Who cited this? | PubMed ID: 16719051 | Fulltext

Estimation of pancreas weight from donor variables.

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Kin T, Murdoch TB, Shapiro AM, and Lakey JR

Cell transplantation 15(2):181-5, 2006 - Who cited this? | PubMed ID: 16719052 | Fulltext

Ameliorating injury during preservation and isolation of human islets using the two-layer method with perfluorocarbon and UW solution.

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Salehi P, Mirbolooki M, Kin T, Tsujimura T, Shapiro AM, Churchill TA, and Lakey JR

Cell transplantation 15(2):187-94, 2006 - Who cited this? | PubMed ID: 16719053 | Fulltext

Current status of clinical islet cell transplantation.

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Lakey JR, Mirbolooki M, and Shapiro AM

Methods in molecular biology (Clifton, N.J.) 333:47-104, 2006 - Who cited this? | PubMed ID: 16790847 | Fulltext

Stem cell sources for clinical islet transplantation in type 1 diabetes: embryonic and adult stem cells.

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Miszta-Lane H, Mirbolooki M, James Shapiro AM, and Lakey JR

Medical hypotheses 67(4):909-13, 2006 - Who cited this? | PubMed ID: 16762516 | Fulltext

Maintenance of mouse, rat, and pig pancreatic islet functions by coculture with human islet-derived fibroblasts.

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Miki A, Narushima M, Okitsu T, Takeno Y, Soto-Gutierrez A, Rivas-Carrillo JD, Navarro-Alvarez N, Chen Y, Tanaka K, Noguchi H, Matsumoto S, Kohara M, Lakey JR, Kobayashi E, Tanaka N, and Kobayashi N

Cell transplantation 15(4):325-34, 2006 - Who cited this? | PubMed ID: 16898226 | Fulltext

Prevention of bleeding after islet transplantation: lessons learned from a multivariate analysis of 132 cases at a single institution.

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Villiger P, Ryan EA, Owen R, O'Kelly K, Oberholzer J, Al Saif F, Kin T, Wang H, Larsen I, Blitz SL, Menon V, Senior P, Bigam DL, Paty B, Kneteman NM, Lakey JR,

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American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 5(12):2992, 2005 Dec - Who cited this? | PubMed ID: 16303015 | Fulltext

Sirolimus-induced ulceration of the small bowel in islet transplant recipients: report of two cases.

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Molinari M, Al-Saif F, Ryan EA, Lakey JR, Senior PA, Paty BW, Bigam DL, Kneteman NM, and Shapiro AM

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 5(11):2799, 2005 Nov - Who cited this? | PubMed ID: 16212644 | Fulltext

Islet auto-transplantation into an omental or splenic site results in a normal beta cell but abnormal alpha cell response to mild non-insulin-induced hypoglycemia.

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Gustavson SM, Rajotte RV, Hunkeler D, Lakey JR, Edgerton DS, Neal DW, Snead WL, Penaloza AR, and Cherrington AD

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 5(10):2368, 2005 Oct - Who cited this? | PubMed ID: 16162184 | Fulltext

A human beta-cell line for transplantation therapy to control type 1 diabetes.

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Narushima M, Kobayashi N, Okitsu T, Tanaka Y, Li SA, Chen Y, Miki A, Tanaka K, Nakaji S, Takei K, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Jun HS, Westerman KA, Noguchi H,

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Nature biotechnology 23(10):1274-82, 2005 Oct - Who cited this? | PubMed ID: 16186810 | Fulltext

Multi-lot analysis of custom collagenase enzyme blend in human islet isolations.

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O'Gorman D, Kin T, McGhee-Wilson D, Shapiro AM, and Lakey JR

Transplantation proceedings 37(8):3417-9, 2005 Oct - Who cited this? | PubMed ID: 16298613 | Fulltext

Quantitative assessment of collagenase blends for human islet isolation.

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Barnett MJ, Zhai X, LeGatt DF, Cheng SB, Shapiro AM, and Lakey JR

Transplantation 80(6):723-8, 2005 Sep 27 - Who cited this? | PubMed ID: 16210957 | Fulltext

The standardization of pancreatic donors for islet isolations.

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O'Gorman D, Kin T, Murdoch T, Richer B, McGhee-Wilson D, Ryan EA, Shapiro JA, and Lakey JR

Transplantation 80(6):801-6, 2005 Sep 27 - Who cited this? | PubMed ID: 16210968 | Fulltext

XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes.

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Emamaullee JA, Rajotte RV, Liston P, Korneluk RG, Lakey JR, Shapiro AM, and Elliott JF

Diabetes 54(9):2541, 2005 Sep - Who cited this? | PubMed ID: 16123341 | Fulltext

Decellularization reduces the immune response to aortic valve allografts in the rat.

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Meyer SR, Nagendran J, Desai LS, Rayat GR, Churchill TA, Anderson CC, Rajotte RV, Lakey JR, and Ross DB

The Journal of thoracic and cardiovascular surgery 130(2):469-76, 2005 Aug - Who cited this? | PubMed ID: 16077415 | Fulltext

Five-year follow-up after clinical islet transplantation.

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Ryan EA, Paty BW, Senior PA, Bigam D, Alfadhli E, Kneteman NM, Lakey JR, and Shapiro AM

Diabetes 54(7):2060-9, 2005 Jul - Who cited this? | PubMed ID: 15983207 | Fulltext

Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass.

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Suarez-Pinzon WL, Lakey JR, Brand SJ, and Rabinovitch A

The Journal of clinical endocrinology and metabolism 90(6):3401-9, 2005 Jun - Who cited this? | PubMed ID: 15769977 | Fulltext

Strategic opportunities in clinical islet transplantation.

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Shapiro AM, Lakey JR, Paty BW, Senior PA, Bigam DL, and Ryan EA

Transplantation 79(10):1304-7, 2005 May 27 - Who cited this? | PubMed ID: 15912095 | Fulltext

Pancreas divisum: a study of the cadaveric donor pancreas for islet isolation.

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Kin T, Shapiro AM, and Lakey JR

Pancreas 30(4):325-7, 2005 May - Who cited this? | PubMed ID: 15841041 | Fulltext

Islet isolation and transplantation from an annular pancreas: a case report.

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Kin T, Shapiro J, Ryan EA, and Lakey JR

JOP : Journal of the pancreas 6(3):274-6, 2005 May - Who cited this? | PubMed ID: 15883480 | Fulltext

Use of an allograft patch in repair of hypoplastic left heart syndrome may complicate future transplantation.

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Meyer SR, Campbell PM, Rutledge JM, Halpin AM, Hawkins LE, Lakey JR, Rebeyka IM, and Ross DB

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 27(4):554-60, 2005 Apr - Who cited this? | PubMed ID: 15784350 | Fulltext

The standardization of pancreatic donors for islet isolation.

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O'Gorman D, Kin T, Murdoch T, Richer B, McGhee-Wilson D, Ryan E, Shapiro AM, and Lakey JR

Transplantation proceedings 37(2):1309-10, 2005 Mar - Who cited this? | PubMed ID: 15848705 | Fulltext

The portal immunosuppressive storm: relevance to islet transplantation?.

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Shapiro AM, Gallant HL, Hao EG, Lakey JR, McCready T, Rajotte RV, Yatscoff RW, and Kneteman NM

Therapeutic drug monitoring 27(1):35-7, 2005 Feb - Who cited this? | PubMed ID: 15665744 | Fulltext

Beta-score: an assessment of beta-cell function after islet transplantation.

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Ryan EA, Paty BW, Senior PA, Lakey JR, Bigam D, and Shapiro AM

Diabetes care 28(2):343-7, 2005 Feb - Who cited this? | PubMed ID: 15677790 | Fulltext

Clinical islet transplantation at the University of Alberta--the Edmonton experience.

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Truong W, Lakey JR, Ryan EA, and Shapiro AM

Clinical transplants:153-72, 2005 - Who cited this? | PubMed ID: 17424733 | Fulltext

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