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Papers authored by Kroon PA

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Hypoxia-inducible factor-1 (HIF-1) pathway activation by quercetin in human lens epithelial cells.

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Radreau P, Rhodes JD, Mithen RF, Kroon PA, and Sanderson J

Experimental eye research 89(6):995-1002, 2009 Dec - Who cited this? | PubMed ID: 19729006 | Fulltext

The biological responses to resveratrol and other polyphenols from alcoholic beverages.

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Brown L, Kroon PA, Das DK, Das S, Tosaki A, Chan V, Singer MV, and Feick P

Alcoholism, clinical and experimental research 33(9):1513-23, 2009 Sep - Who cited this? | PubMed ID: 19519720 | Fulltext

Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta.

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Lodi F, Jimenez R, Moreno L, Kroon PA, Needs PW, Hughes DA, Santos-Buelga C, Gonzalez-Paramas A, Cogolludo A, Lopez-Sepulveda R, Duarte J, and Perez-Vizcaino F

Atherosclerosis 204(1):34-9, 2009 May - Who cited this? | PubMed ID: 18801486 | Fulltext

The bioactivity of dietary anthocyanins is likely to be mediated by their degradation products.

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Kay CD, Kroon PA, and Cassidy A

Molecular nutrition & food research 53 Suppl 1:S92-101, 2009 May - Who cited this? | PubMed ID: 19415657 | Fulltext

Oligomeric procyanidins inhibit cell migration and modulate the expression of migration and proliferation associated genes in human umbilical vascular endothelial cells.

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García-Conesa MT, Tribolo S, Guyot S, Tomás-Barberán FA, and Kroon PA

Molecular nutrition & food research 53(2):266-76, 2009 Feb - Who cited this? | PubMed ID: 18979505 | Fulltext

Urinary excretion of strawberry anthocyanins is dose dependent for physiological oral doses of fresh fruit.

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Hollands W, Brett GM, Dainty JR, Teucher B, and Kroon PA

Molecular nutrition & food research 52(10):1097-105, 2008 Oct - Who cited this? | PubMed ID: 18645999 | Fulltext

A comparative study of the effects of quercetin and its glucuronide and sulfate metabolites on human neutrophil function in vitro.

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Suri S, Taylor MA, Verity A, Tribolo S, Needs PW, Kroon PA, Hughes DA, and Wilson VG

Biochemical pharmacology 76(5):645-53, 2008 Sep 1 - Who cited this? | PubMed ID: 18639531 | Fulltext

Absorption, metabolism and excretion of flavanones from single portions of orange fruit and juice and effects of anthropometric variables and contraceptive pill use on flavanone excretion.

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Brett GM, Hollands W, Needs PW, Teucher B, R Dainty J, Davis BD, Brodbelt JS, and Kroon PA

The British journal of nutrition:1, 2008 Aug 19 - Who cited this? | PubMed ID: 18710603 | Fulltext

Procyanidin effects on oesophageal adenocarcinoma cells strongly depend on flavan-3-ol degree of polymerization.

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Pierini R, Kroon PA, Guyot S, Ivory K, Johnson IT, and Belshaw NJ

Molecular nutrition & food research, 2008 Aug 6 - Who cited this? | PubMed ID: 18683822 | Fulltext

Flavonoids, flavonoid-rich foods, and cardiovascular risk: a meta-analysis of randomized controlled trials.

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Hooper L, Kroon PA, Rimm EB, Cohn JS, Harvey I, Le Cornu KA, Ryder JJ, Hall WL, and Cassidy A

The American journal of clinical nutrition 88(1):38, 2008 Jul - Who cited this? | PubMed ID: 18614722 | Fulltext

The procyanidin-mediated induction of apoptosis and cell-cycle arrest in esophageal adenocarcinoma cells is not dependent on p21(Cip1/WAF1).

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Pierini R, Kroon PA, Guyot S, Johnson IT, and Belshaw NJ

Cancer letters, 2008 Jun 16 - Who cited this? | PubMed ID: 18562088 | Fulltext

Quercetin and its in vivo metabolites inhibit neutrophil-mediated low-density lipoprotein oxidation.

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Loke WM, Proudfoot JM, McKinley AJ, Needs PW, Kroon PA, Hodgson JM, and Croft KD

Journal of agricultural and food chemistry 56(10):3609-15, 2008 May 28 - Who cited this? | PubMed ID: 18454540 | Fulltext

Physiologically relevant metabolites of quercetin have no effect on adhesion molecule or chemokine expression in human vascular smooth muscle cells.

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Winterbone MS, Tribolo S, Needs PW, Kroon PA, and Hughes DA

Atherosclerosis, 2008 May 1 - Who cited this? | PubMed ID: 18489909 | Fulltext

Metabolic transformation has a profound effect on anti-inflammatory activity of flavonoids such as quercetin: Lack of association between antioxidant and lipoxygenase inhibitory activity.

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Loke WM, Proudfoot JM, Stewart S, McKinley AJ, Needs PW, Kroon PA, Hodgson JM, and Croft KD

Biochemical pharmacology 75(5):1045-53, 2008 Mar 1 - Who cited this? | PubMed ID: 18096136 | Fulltext

Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells.

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Tribolo S, Lodi F, Connor C, Suri S, Wilson VG, Taylor MA, Needs PW, Kroon PA, and Hughes DA

Atherosclerosis 197(1):50-6, 2008 Mar - Who cited this? | PubMed ID: 17880982 | Fulltext

Interaction of positional isomers of quercetin glucuronides with the transporter ABCC2 (cMOAT, MRP2).

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Williamson G, Aeberli I, Miguet L, Zhang Z, Sanchez MB, Crespy V, Barron D, Needs P, Kroon PA, Glavinas H, Krajcsi P, and Grigorov M

Drug metabolism and disposition: the biological fate of chemicals 35(8):1262-8, 2007 Aug - Who cited this? | PubMed ID: 17478601 | Fulltext

The crystal structure of human cytosolic beta-glucosidase unravels the substrate aglycone specificity of a family 1 glycoside hydrolase.

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Tribolo S, Berrin JG, Kroon PA, Czjzek M, and Juge N

Journal of molecular biology 370(5):964-75, 2007 Jul 27 - Who cited this? | PubMed ID: 17555766 | Fulltext

Identification of isomeric flavonoid glucuronides in urine and plasma by metal complexation and LC-ESI-MS/MS.

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Davis BD, Needs PW, Kroon PA, and Brodbelt JS

Journal of mass spectrometry : JMS 41(7):911-20, 2006 Jul - Who cited this? | PubMed ID: 16810646 | Fulltext

Ontogenic profiling of glucosinolates, flavonoids, and other secondary metabolites in Eruca sativa (salad rocket), Diplotaxis erucoides (wall rocket), Diplotaxis tenuifolia (wild rocket), and Bunias orientalis (Turkish rocket).

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Bennett RN, Rosa EA, Mellon FA, and Kroon PA

Journal of agricultural and food chemistry 54(11):4005-15, 2006 May 31 - Who cited this? | PubMed ID: 16719527 | Fulltext

AFM studies of water-soluble wheat arabinoxylans--effects of esterase treatment.

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Adams EL, Kroon PA, Williamson G, and Morris VJ

Carbohydrate research 340(11):1841-5, 2005 Aug 15 - Who cited this? | PubMed ID: 15993866 | Fulltext

Changes in neuronal protein 22 expression and cytoskeletal association in the alcohol-dependent and withdrawn rat brain.

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Depaz IM, de Las Heras R, Kroon PA, and Wilce PA

Journal of neuroscience research 81(2):253-60, 2005 Jul 15 - Who cited this? | PubMed ID: 15948156 | Fulltext

Profiling glucosinolates, flavonoids, alkaloids, and other secondary metabolites in tissues of Azima tetracantha L. (Salvadoraceae).

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Bennett RN, Mellon FA, Rosa EA, Perkins L, and Kroon PA

Journal of agricultural and food chemistry 52(19):5856-62, 2004 Sep 22 - Who cited this? | PubMed ID: 15366832 | Fulltext

Isolation, identification and stability of acylated derivatives of apigenin 7-O-glucoside from chamomile (Chamomilla recutita [L.] Rauschert).

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Svehliková V, Bennett RN, Mellon FA, Needs PW, Piacente S, Kroon PA, and Bao Y

Phytochemistry 65(16):2323-32, 2004 Aug - Who cited this? | PubMed ID: 15381003 | Fulltext

How should we assess the effects of exposure to dietary polyphenols in vitro?.

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Kroon PA, Clifford MN, Crozier A, Day AJ, Donovan JL, Manach C, and Williamson G

The American journal of clinical nutrition 80(1):15-21, 2004 Jul - Who cited this? | PubMed ID: 15213022 | Fulltext

Absorption of kaempferol from endive, a source of kaempferol-3-glucuronide, in humans.

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DuPont MS, Day AJ, Bennett RN, Mellon FA, and Kroon PA

European journal of clinical nutrition 58(6):947-54, 2004 Jun - Who cited this? | PubMed ID: 15164116 | Fulltext

The feruloyl esterase system of Talaromyces stipitatus: production of three discrete feruloyl esterases, including a novel enzyme, TsFaeC, with a broad substrate specificity.

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Garcia-Conesa MT, Crepin VF, Goldson AJ, Williamson G, Cummings NJ, Connerton IF, Faulds CB, and Kroon PA

Journal of biotechnology 108(3):227-41, 2004 Mar 18 - Who cited this? | PubMed ID: 15006424 | Fulltext

Inactivated enzymes as probes of the structure of arabinoxylans as observed by atomic force microscopy.

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Adams EL, Kroon PA, Williamson G, Gilbert HJ, and Morris VJ

Carbohydrate research 339(3):579-90, 2004 Feb 25 - Who cited this? | PubMed ID: 15013394 | Fulltext

Occurrence of proteinaceous endoxylanase inhibitors in cereals.

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Goesaert H, Elliott G, Kroon PA, Gebruers K, Courtin CM, Robben J, Delcour JA, and Juge N

Biochimica et biophysica acta 1696(2):193-202, 2004 Feb 12 - Who cited this? | PubMed ID: 14871660 | Fulltext

Screening crucifer seeds as sources of specific intact glucosinolates using ion-pair high-performance liquid chromatography negative ion electrospray mass spectrometry.

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Bennett RN, Mellon FA, and Kroon PA

Journal of agricultural and food chemistry 52(3):428, 2004 Feb 11 - Who cited this? | PubMed ID: 14759128 | Fulltext

Characterization of metabolites of hydroxycinnamates in the in vitro model of human small intestinal epithelium caco-2 cells.

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Kern SM, Bennett RN, Needs PW, Mellon FA, Kroon PA, and Garcia-Conesa MT

Journal of agricultural and food chemistry 51(27):7884-91, 2003 Dec 31 - Who cited this? | PubMed ID: 14690369 | Fulltext

Drinking your health? It's too early to say.

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Corder R, Crozier A, and Kroon PA

Nature 426(6963):119, 2003 Nov 13 - Who cited this? | PubMed ID: 14614475 | Fulltext

Conformational changes in SP-B as a function of surface pressure.

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Fullagar WK, Aberdeen KA, Bucknall DG, Kroon PA, and Gentle IR

Biophysical journal 85(4):2624-32, 2003 Oct - Who cited this? | PubMed ID: 14507725 | Fulltext

Absorption of hydroxycinnamates in humans after high-bran cereal consumption.

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Kern SM, Bennett RN, Mellon FA, Kroon PA, and Garcia-Conesa MT

Journal of agricultural and food chemistry 51(20):6050-5, 2003 Sep 24 - Who cited this? | PubMed ID: 13129315 | Fulltext

Substrate (aglycone) specificity of human cytosolic beta-glucosidase.

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Berrin JG, Czjzek M, Kroon PA, McLauchlan WR, Puigserver A, Williamson G, and Juge N

The Biochemical journal 373(Pt 1):41-8, 2003 Jul 1 - Who cited this? | PubMed ID: 12667141 | Fulltext

Profiling glucosinolates and phenolics in vegetative and reproductive tissues of the multi-purpose trees Moringa oleifera L. (horseradish tree) and Moringa stenopetala L.

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Bennett RN, Mellon FA, Foidl N, Pratt JH, Dupont MS, Perkins L, and Kroon PA

Journal of agricultural and food chemistry 51(12):3546-53, 2003 Jun 4 - Who cited this? | PubMed ID: 12769522 | Fulltext

Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo.

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Petri N, Tannergren C, Holst B, Mellon FA, Bao Y, Plumb GW, Bacon J, O'Leary KA, Kroon PA, Knutson L, Forsell P, Eriksson T, Lennernas H, and Williamson G

Drug metabolism and disposition: the biological fate of chemicals 31(6):805-13, 2003 Jun - Who cited this? | PubMed ID: 12756216 | Fulltext

Characterisation of heterogeneous arabinoxylans by direct imaging of individual molecules by atomic force microscopy.

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Adams EL, Kroon PA, Williamson G, and Morris VJ

Carbohydrate research 338(8):771-80, 2003 Apr 4 - Who cited this? | PubMed ID: 12668097 | Fulltext

Comparison of modular and non-modular xylanases as carrier proteins for the efficient secretion of heterologous proteins from Penicillium funiculosum.

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Alcocer MJ, Furniss CS, Kroon PA, Campbell M, and Archer DB

Applied microbiology and biotechnology 60(6):726-32, 2003 Feb - Who cited this? | PubMed ID: 12664153 | Fulltext

Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans.

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Németh K, Plumb GW, Berrin JG, Juge N, Jacob R, Naim HY, Williamson G, Swallow DM, and Kroon PA

European journal of nutrition 42(1):29-42, 2003 Jan - Who cited this? | PubMed ID: 12594539 | Fulltext

A family 11 xylanase from Penicillium funiculosum is strongly inhibited by three wheat xylanase inhibitors.

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Furniss CS, Belshaw NJ, Alcocer MJ, Williamson G, Elliott GO, Gebruers K, Haigh NP, Fish NM, and Kroon PA

Biochimica et biophysica acta 1598(1-2):24-9, 2002 Jul 29 - Who cited this? | PubMed ID: 12147340 | Fulltext

Functional identification of the cDNA coding for a wheat endo-1,4-beta-D-xylanase inhibitor.

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Elliott GO, Hughes RK, Juge N, Kroon PA, and Williamson G

FEBS letters 519(1-3):66-70, 2002 May 22 - Who cited this? | PubMed ID: 12023019 | Fulltext

Functional expression of human liver cytosolic beta-glucosidase in Pichia pastoris. Insights into its role in the metabolism of dietary glucosides.

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Berrin JG, McLauchlan WR, Needs P, Williamson G, Puigserver A, Kroon PA, and Juge N

European journal of biochemistry / FEBS 269(1):249-58, 2002 Jan - Who cited this? | PubMed ID: 11784319 | Fulltext

Esterase activity able to hydrolyze dietary antioxidant hydroxycinnamates is distributed along the intestine of mammals.

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Andreasen MF, Kroon PA, Williamson G, and Garcia-Conesa MT

Journal of agricultural and food chemistry 49(11):5679-84, 2001 Nov - Who cited this? | PubMed ID: 11714377 | Fulltext

NMR structure and backbone dynamics of a concatemer of epidermal growth factor homology modules of the human low-density lipoprotein receptor.

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Kurniawan ND, Aliabadizadeh K, Brereton IM, Kroon PA, and Smith R

Journal of molecular biology 311(2):341-56, 2001 Aug 10 - Who cited this? | PubMed ID: 11478865 | Fulltext

Intestinal release and uptake of phenolic antioxidant diferulic acids.

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Andreasen MF, Kroon PA, Williamson G, and Garcia-Conesa MT

Free radical biology & medicine 31(3):304-14, 2001 Aug 1 - Who cited this? | PubMed ID: 11461767 | Fulltext

A modular esterase from Penicillium funiculosum which releases ferulic acid from plant cell walls and binds crystalline cellulose contains a carbohydrate binding module.

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Kroon PA, Williamson G, Fish NM, Archer DB, and Belshaw NJ

European journal of biochemistry / FEBS 267(23):6740-52, 2000 Dec - Who cited this? | PubMed ID: 11082184 | Fulltext

Three-dimensional NMR structure of the sixth ligand-binding module of the human LDL receptor: comparison of two adjacent modules with different ligand binding specificities.

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Clayton D, Brereton IM, Kroon PA, and Smith R

FEBS letters 479(3):118-22, 2000 Aug 18 - Who cited this? | PubMed ID: 10981718 | Fulltext

NMR structure of a concatemer of the first and second ligand-binding modules of the human low-density lipoprotein receptor.

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Kurniawan ND, Atkins AR, Bieri S, Brown CJ, Brereton IM, Kroon PA, and Smith R

Protein science : a publication of the Protein Society 9(7):1282-93, 2000 Jul - Who cited this? | PubMed ID: 10933493 | Fulltext

Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase.

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Day AJ, Cañada FJ, Díaz JC, Kroon PA, Mclauchlan R, Faulds CB, Plumb GW, Morgan MR, and Williamson G

FEBS letters 468(2-3):166-70, 2000 Feb 25 - Who cited this? | PubMed ID: 10692580 | Fulltext

A cinnamoyl esterase from Aspergillus niger can break plant cell wall cross-links without release of free diferulic acids.

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Garcia-Conesa MT, Kroon PA, Ralph J, Mellon FA, Colquhoun IJ, Saulnier L, Thibault JF, and Williamson G

European journal of biochemistry / FEBS 266(2):644-52, 1999 Dec - Who cited this? | PubMed ID: 10561608 | Fulltext

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