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Papers authored by Kranz DM

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Different Strategies Adopted by Kb and Ld to Generate T Cell Specificity Directed against Their Respective Bound Peptides.

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Bowerman NA, Colf LA, Garcia KC, and Kranz DM

The Journal of biological chemistry 284(47):32551-61, 2009 Nov 20 - Who cited this? | PubMed ID: 19755422 | Fulltext

Engineering the binding properties of the T cell receptor:peptide:MHC ternary complex that governs T cell activity.

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Bowerman NA, Crofts TS, Chlewicki L, Do P, Baker BM, Christopher Garcia K, and Kranz DM

Molecular immunology 46(15):3000-8, 2009 Sep - Who cited this? | PubMed ID: 19595460 | Fulltext

Imaging membrane intercalating near infrared dyes to track multiple cell populations.

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Roy EJ, Sivaguru M, Fried G, Gray BD, and Kranz DM

Journal of immunological methods 348(1-2):18-29, 2009 Aug 31 - Who cited this? | PubMed ID: 19559026 | Fulltext

Recurrence of intracranial tumors following adoptive T cell therapy can be prevented by direct and indirect killing aided by high levels of tumor antigen cross-presented on stromal cells.

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Thomas DL, Kim M, Bowerman NA, Narayanan S, Kranz DM, Schreiber H, and Roy EJ

Journal of immunology (Baltimore, Md. : 1950) 183(3):1828-37, 2009 Aug 1 - Who cited this? | PubMed ID: 19592642 | Fulltext

The Impact of TCR-Binding Properties and Antigen Presentation Format on T Cell Responsiveness.

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Chervin AS, Stone JD, Holler PD, Bai A, Chen J, Eisen HN, and Kranz DM

Journal of immunology (Baltimore, Md. : 1950) 183(2):1166-78, 2009 Jul 15 - Who cited this? | PubMed ID: 19553539 | Fulltext

T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity.

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Stone JD, Chervin AS, and Kranz DM

Immunology 126(2):165-76, 2009 Feb - Who cited this? | PubMed ID: 19125887 | Fulltext

Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragments.

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Richman SA, Aggen DH, Dossett ML, Donermeyer DL, Allen PM, Greenberg PD, and Kranz DM

Molecular immunology 46(5):902-16, 2009 Feb - Who cited this? | PubMed ID: 18962897 | Fulltext

Biosensor detection systems: engineering stable, high-affinity bioreceptors by yeast surface display.

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Richman SA, Kranz DM, and Stone JD

Methods in molecular biology (Clifton, N.J.) 504:323-50, 2009 - Who cited this? | PubMed ID: 19159105 | Fulltext

Engineering higher affinity T cell receptors using a T cell display system.

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Chervin AS, Aggen DH, Raseman JM, and Kranz DM

Journal of immunological methods 339(2):175-84, 2008 Dec 31 - Who cited this? | PubMed ID: 18854190 | Fulltext

Distinct CDR3 Conformations in TCRs Determine the Level of Cross-Reactivity for Diverse Antigens, but Not the Docking Orientation.

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Jones LL, Colf LA, Stone JD, Garcia KC, and Kranz DM

Journal of immunology (Baltimore, Md. : 1950) 181(9):6255-64, 2008 Nov 1 - Who cited this? | PubMed ID: 18941216 | Fulltext

Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors.

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Jones LL, Colf LA, Bankovich AJ, Stone JD, Gao YG, Chan CM, Huang RH, Garcia KC, and Kranz DM

Biochemistry, 2008 Oct 31 - Who cited this? | PubMed ID: 18973345 | Fulltext

Experimental manipulations of afferent immune responses influence efferent immune responses to brain tumors.

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Thomas DL, Kranz DM, and Roy EJ

Cancer immunology, immunotherapy : CII 57(9):1323-33, 2008 Sep - Who cited this? | PubMed ID: 18278494 | Fulltext

Neutralization of Multiple Staphylococcal Superantigens by a Single-Chain Protein Consisting of Affinity-Matured, Variable Domain Repeats.

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Yang X, Buonpane RA, Moza B, Rahman AK, Wang N, Schlievert PM, McCormick JK, Sundberg EJ, and Kranz DM

The Journal of infectious diseases, 2008 Jun 3 - Who cited this? | PubMed ID: 18522504 | Fulltext

Costimulatory strength influences the differential effects of transforming growth factor beta1 for the generation of CD8+ regulatory T cells.

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Fan TM, Kranz DM, Flavell RA, and Roy EJ

Molecular immunology 45(10):2937, 2008 May - Who cited this? | PubMed ID: 18321576 | Fulltext

Equilibrium between host and cancer caused by effector T cells killing tumor stroma.

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Zhang B, Zhang Y, Bowerman NA, Schietinger A, Fu YX, Kranz DM, Rowley DA, and Schreiber H

Cancer research 68(5):1563-71, 2008 Mar 1 - Who cited this? | PubMed ID: 18316622 | Fulltext

Display, engineering, and applications of antigen-specific T cell receptors.

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Richman SA and Kranz DM

Biomolecular engineering 24(4):361-73, 2007 Oct - Who cited this? | PubMed ID: 17409021 | Fulltext

Solution mapping of T cell receptor docking footprints on peptide-MHC.

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Varani L, Bankovich AJ, Liu CW, Colf LA, Jones LL, Kranz DM, Puglisi JD, and Garcia KC

Proceedings of the National Academy of Sciences of the United States of America 104(32):13080, 2007 Aug 7 - Who cited this? | PubMed ID: 17670943 | Fulltext

Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists.

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Buonpane RA, Churchill HR, Moza B, Sundberg EJ, Peterson ML, Schlievert PM, and Kranz DM

Nature medicine 13(6):725-9, 2007 Jun - Who cited this? | PubMed ID: 17515896 | Fulltext

Disulfide bond engineering to trap peptides in the MHC class I binding groove.

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Truscott SM, Lybarger L, Martinko JM, Mitaksov VE, Kranz DM, Connolly JM, Fremont DH, and Hansen TH

Journal of immunology (Baltimore, Md. : 1950) 178(10):6280-9, 2007 May 15 - Who cited this? | PubMed ID: 17475856 | Fulltext

How a single T cell receptor recognizes both self and foreign MHC.

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Colf LA, Bankovich AJ, Hanick NA, Bowerman NA, Jones LL, Kranz DM, and Garcia KC

Cell 129(1):135, 2007 Apr 6 - Who cited this? | PubMed ID: 17418792 | Fulltext

Cellular uptake followed by class I MHC presentation of some exogenous peptides contributes to T cell stimulatory capacity.

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Brophy SE, Jones LL, Holler PD, and Kranz DM

Molecular immunology 44(9):2184-94, 2007 Mar - Who cited this? | PubMed ID: 17169430 | Fulltext

Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1.

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Moza B, Varma AK, Buonpane RA, Zhu P, Herfst CA, Nicholson MJ, Wilbuer AK, Seth NP, Wucherpfennig KW, McCormick JK, Kranz DM, and Sundberg EJ

The EMBO journal 26(4):1187-97, 2007 Feb 21 - Who cited this? | PubMed ID: 17268555 | Fulltext

Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC.

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Wang L, Zhao Y, Li Z, Guo Y, Jones LL, Kranz DM, Mourad W, and Li H

Nature structural & molecular biology 14(2):169-71, 2007 Feb - Who cited this? | PubMed ID: 17220897 | Fulltext

Induced sensitization of tumor stroma leads to eradication of established cancer by T cells.

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Zhang B, Bowerman NA, Salama JK, Schmidt H, Spiotto MT, Schietinger A, Yu P, Fu YX, Weichselbaum RR, Rowley DA, Kranz DM, and Schreiber H

The Journal of experimental medicine 204(1):49-55, 2007 Jan 22 - Who cited this? | PubMed ID: 17210731 | Fulltext

Enhancing antitumor immunity: combining IL-12 with TGFbeta1 antagonism.

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Fan TM, Kranz DM, and Roy EJ

Journal of immunotherapy (Hagerstown, Md. : 1997) 30(5):479-89, 2007 - Who cited this? | PubMed ID: 17589288 | Fulltext

The study of high-affinity TCRs reveals duality in T cell recognition of antigen: specificity and degeneracy.

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Donermeyer DL, Weber KS, Kranz DM, and Allen PM

Journal of immunology (Baltimore, Md. : 1950) 177(10):6911-9, 2006 Nov 15 - Who cited this? | PubMed ID: 17082606 | Fulltext

Engineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld.

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Jones LL, Brophy SE, Bankovich AJ, Colf LA, Hanick NA, Garcia KC, and Kranz DM

The Journal of biological chemistry 281(35):25734, 2006 Sep 1 - Who cited this? | PubMed ID: 16815841 | Fulltext

Long-range cooperative binding effects in a T cell receptor variable domain.

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Moza B, Buonpane RA, Zhu P, Herfst CA, Rahman AK, McCormick JK, Kranz DM, and Sundberg EJ

Proceedings of the National Academy of Sciences of the United States of America 103(26):9867-72, 2006 Jun 27 - Who cited this? | PubMed ID: 16788072 | Fulltext

Development of a novel strategy for engineering high-affinity proteins by yeast display.

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Richman SA, Healan SJ, Weber KS, Donermeyer DL, Dossett ML, Greenberg PD, Allen PM, and Kranz DM

Protein engineering, design & selection : PEDS 19(6):255, 2006 Jun - Who cited this? | PubMed ID: 16549400 | Fulltext

Estrogen induction of the granzyme B inhibitor, proteinase inhibitor 9, protects cells against apoptosis mediated by cytotoxic T lymphocytes and natural killer cells.

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Jiang X, Orr BA, Kranz DM, and Shapiro DJ

Endocrinology 147(3):1419-26, 2006 Mar - Who cited this? | PubMed ID: 16306080 | Fulltext

Class II-restricted T cell receptor engineered in vitro for higher affinity retains peptide specificity and function.

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Weber KS, Donermeyer DL, Allen PM, and Kranz DM

Proceedings of the National Academy of Sciences of the United States of America 102(52):19033-8, 2005 Dec 27 - Who cited this? | PubMed ID: 16365315 | Fulltext

Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.

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Cho S, Swaminathan CP, Yang J, Kerzic MC, Guan R, Kieke MC, Kranz DM, Mariuzza RA, and Sundberg EJ

Structure (London, England : 1993) 13(12):1775, 2005 Dec - Who cited this? | PubMed ID: 16338406 | Fulltext

Neuronal localization of indoleamine 2,3-dioxygenase in mice.

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Roy EJ, Takikawa O, Kranz DM, Brown AR, and Thomas DL

Neuroscience letters 387(2):95-9, 2005 Oct 21 - Who cited this? | PubMed ID: 16076525 | Fulltext

Characterization of T cell receptors engineered for high affinity against toxic shock syndrome toxin-1.

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Buonpane RA, Moza B, Sundberg EJ, and Kranz DM

Journal of molecular biology 353(2):308-21, 2005 Oct 21 - Who cited this? | PubMed ID: 16171815 | Fulltext

High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3.

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Chlewicki LK, Holler PD, Monti BC, Clutter MR, and Kranz DM

Journal of molecular biology 346(1):223-39, 2005 Feb 11 - Who cited this? | PubMed ID: 15663940 | Fulltext

T cell receptor CDRs: starring versus supporting roles.

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Kranz DM

Nature immunology 6(2):130-2, 2005 Feb - Who cited this? | PubMed ID: 15662440 | Fulltext

Targeting virus entry and membrane fusion through specific peptide/MHC complexes using a high-affinity T-cell receptor.

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Peng KW, Holler PD, Orr BA, Kranz DM, and Russell SJ

Gene therapy 11(15):1234-9, 2004 Aug - Who cited this? | PubMed ID: 15215883 | Fulltext

Folate-mediated targeting of T cells to tumors.

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Roy EJ, Gawlick U, Orr BA, and Kranz DM

Advanced drug delivery reviews 56(8):1219-31, 2004 Apr 29 - Who cited this? | PubMed ID: 15094217 | Fulltext

Expression profiling using a hexamer-based universal microarray.

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Roth ME, Feng L, McConnell KJ, Schaffer PJ, Guerra CE, Affourtit JP, Piper KR, Guccione L, Hariharan J, Ford MJ, Powell SW, Krishnaswamy H, Lane J, Guccione L, Intrieri G, Merkel JS,

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Nature biotechnology 22(4):418-26, 2004 Apr - Who cited this? | PubMed ID: 15024387 | Fulltext

T cell receptors: affinities, cross-reactivities, and a conformer model.

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Holler PD and Kranz DM

Molecular immunology 40(14-15):1027-31, 2004 Feb - Who cited this? | PubMed ID: 15036906 | Fulltext

A conjugate of a tumor-targeting ligand and a T cell costimulatory antibody to treat brain tumors.

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Gawlick U, Kranz DM, Schepkin VD, and Roy EJ

Bioconjugate chemistry 15(5):1137-45, 2004 - Who cited this? | PubMed ID: 15366970 | Fulltext

Dissecting cooperative and additive binding energetics in the affinity maturation pathway of a protein-protein interface.

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Yang J, Swaminathan CP, Huang Y, Guan R, Cho S, Kieke MC, Kranz DM, Mariuzza RA, and Sundberg EJ

The Journal of biological chemistry 278(50):50412-21, 2003 Dec 12 - Who cited this? | PubMed ID: 14514664 | Fulltext

The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexes.

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Leifert JA, Holler PD, Harkins S, Kranz DM, and Whitton JL

Gene therapy 10(25):2067-73, 2003 Dec - Who cited this? | PubMed ID: 14595379 | Fulltext

Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).

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Dam J, Guan R, Natarajan K, Dimasi N, Chlewicki LK, Kranz DM, Schuck P, Margulies DH, and Mariuzza RA

Nature immunology 4(12):1213-22, 2003 Dec - Who cited this? | PubMed ID: 14595439 | Fulltext

A model T-cell receptor system for studying memory T-cell development.

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Chen J, Eisen HN, and Kranz DM

Microbes and infection / Institut Pasteur 5(3):233-40, 2003 Mar - Who cited this? | PubMed ID: 12681413 | Fulltext

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation.

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Holler PD and Kranz DM

Immunity 18(2):255-64, 2003 Feb - Who cited this? | PubMed ID: 12594952 | Fulltext

Directed evolution of a single-chain class II MHC product by yeast display.

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Starwalt SE, Masteller EL, Bluestone JA, and Kranz DM

Protein engineering 16(2):147-56, 2003 Feb - Who cited this? | PubMed ID: 12676983 | Fulltext

A yeast display system for engineering functional peptide-MHC complexes.

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Brophy SE, Holler PD, and Kranz DM

Journal of immunological methods 272(1-2):235-46, 2003 Jan 15 - Who cited this? | PubMed ID: 12505727 | Fulltext

Directed evolution of T-cell receptors for binding superantigens.

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Churchill HR and Kranz DM

Methods in molecular biology (Clifton, N.J.) 214:87-99, 2003 - Who cited this? | PubMed ID: 12489456 | Fulltext

Analysis of superantigen binding to soluble T-cell receptors.

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Churchill HR and Kranz DM

Methods in molecular biology (Clifton, N.J.) 214:101-11, 2003 - Who cited this? | PubMed ID: 12489457 | Fulltext

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