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Papers authored by Koeffler HP

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Chromosomal abnormalities and novel disease-related regions in progression from Barrett's esophagus to esophageal adenocarcinoma.

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Akagi T, Ito T, Kato M, Jin Z, Cheng Y, Kan T, Yamamoto G, Olaru A, Kawamata N, Boult J, Soukiasian HJ, Miller CW, Ogawa S, Meltzer SJ, and Koeffler HP

International journal of cancer. Journal international du cancer 125(10):2349-59, 2009 Nov 15 - Who cited this? | PubMed ID: 19670330 | Fulltext

Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells.

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Nishioka C, Ikezoe T, Yang J, Gery S, Koeffler HP, and Yokoyama A

International journal of cancer. Journal international du cancer 125(7):1710-20, 2009 Oct 1 - Who cited this? | PubMed ID: 19507250 | Fulltext

A role for the clock gene per1 in prostate cancer.

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Cao Q, Gery S, Dashti A, Yin D, Zhou Y, Gu J, and Koeffler HP

Cancer research 69(19):7619-25, 2009 Oct 1 - Who cited this? | PubMed ID: 19752089 | Fulltext

Blockade of MEK signaling potentiates 5-Aza-2'-deoxycytidine-induced apoptosis and upregulation of p21(waf1) in acute myelogenous leukemia cells.

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Nishioka C, Ikezoe T, Yang J, Komatsu N, Koeffler HP, and Yokoyama A

International journal of cancer. Journal international du cancer 125(5):1168-76, 2009 Sep 1 - Who cited this? | PubMed ID: 19422044 | Fulltext

Single nucleotide polymorphism genomic arrays analysis of t(8;21) acute myeloid leukemia cells.

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Akagi T, Shih LY, Ogawa S, Gerss J, Moore SR, Schreck R, Kawamata N, Liang DC, Sanada M, Nannya Y, Deneberg S, Zachariadis V, Nordgren A, Song JH, Dugas M, Lehmann S,

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Haematologica 94(9):1301-6, 2009 Sep - Who cited this? | PubMed ID: 19734423 | Fulltext

A novel treatment strategy targeting polo-like kinase 1 in hematological malignancies.

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Ikezoe T, Yang J, Nishioka C, Takezaki Y, Tasaka T, Togitani K, Koeffler HP, and Yokoyama A

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 23(9):1564-76, 2009 Sep - Who cited this? | PubMed ID: 19421227 | Fulltext

Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.

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Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N,

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Nature 460(7257):904-8, 2009 Aug 13 - Who cited this? | PubMed ID: 19620960 | Fulltext

Identified hidden genomic changes in mantle cell lymphoma using high-resolution single nucleotide polymorphism genomic array.

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Kawamata N, Ogawa S, Gueller S, Ross SH, Huynh T, Chen J, Chang A, Nabavi-Nouis S, Megrabian N, Siebert R, Martinez-Climent JA, and Koeffler HP

Experimental hematology 37(8):937-46, 2009 Aug - Who cited this? | PubMed ID: 19477219 | Fulltext

Induction of endoplasmic reticulum stress response by TZD18, a novel dual ligand for peroxisome proliferator-activated receptor alpha/gamma, in human breast cancer cells.

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Zang C, Liu H, Bertz J, Possinger K, Koeffler HP, Elstner E, and Eucker J

Molecular cancer therapeutics 8(8):2296-307, 2009 Aug - Who cited this? | PubMed ID: 19671747 | Fulltext

Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells.

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Thoennissen NH, Iwanski GB, Doan NB, Okamoto R, Lin P, Abbassi S, Song JH, Yin D, Toh M, Xie WD, Said JW, and Koeffler HP

Cancer research 69(14):5876-84, 2009 Jul 15 - Who cited this? | PubMed ID: 19605406 | Fulltext

Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells.

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Akagi T, Yin D, Kawamata N, Bartram CR, Hofmann WK, Song JH, Miller CW, den Boer ML, and Koeffler HP

Leukemia research 33(7):991-6, 2009 Jul - Who cited this? | PubMed ID: 19054556 | Fulltext

Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia.

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Kawamata N, Ogawa S, Seeger K, Kirschner-Schwabe R, Huynh T, Chen J, Megrabian N, Harbott J, Zimmermann M, Henze G, Schrappe M, Bartram CR, and Koeffler HP

International journal of oncology 34(6):1603-12, 2009 Jun - Who cited this? | PubMed ID: 19424578 | Fulltext

Lnk inhibits myeloproliferative disorder-associated JAK2 mutant, JAK2V617F.

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Gery S, Cao Q, Gueller S, Xing H, Tefferi A, and Koeffler HP

Journal of leukocyte biology 85(6):957-65, 2009 Jun - Who cited this? | PubMed ID: 19293402 | Fulltext

Expression of the adaptor protein Lnk in leukemia cells.

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Gery S, Gueller S, Nowak V, Sohn J, Hofmann WK, and Koeffler HP

Experimental hematology 37(5):585-592.e2, 2009 May - Who cited this? | PubMed ID: 19375649 | Fulltext

High-resolution genomic copy number profiling of glioblastoma multiforme by single nucleotide polymorphism DNA microarray.

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Yin D, Ogawa S, Kawamata N, Tunici P, Finocchiaro G, Eoli M, Ruckert C, Huynh T, Liu G, Kato M, Sanada M, Jauch A, Dugas M, Black KL, and Koeffler HP

Molecular cancer research : MCR 7(5):665-77, 2009 May - Who cited this? | PubMed ID: 19435819 | Fulltext

Differentiation therapy of leukemia: 3 decades of development.

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Nowak D, Stewart D, and Koeffler HP

Blood 113(16):3655-65, 2009 Apr 16 - Who cited this? | PubMed ID: 19221035 | Fulltext

Molecular allelokaryotyping of T-cell prolymphocytic leukemia cells with high density single nucleotide polymorphism arrays identifies novel common genomic lesions and acquired uniparental disomy.

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Nowak D, Le Toriellec E, Stern MH, Kawamata N, Akagi T, Dyer MJ, Hofmann WK, Ogawa S, and Koeffler HP

Haematologica 94(4):518-27, 2009 Apr - Who cited this? | PubMed ID: 19278963 | Fulltext

Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterations.

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Akagi T, Shih LY, Kato M, Kawamata N, Yamamoto G, Sanada M, Okamoto R, Miller CW, Liang DC, Ogawa S, and Koeffler HP

Blood 113(8):1741-8, 2009 Feb 19 - Who cited this? | PubMed ID: 19109227 | Fulltext

Epigenetic regulation and molecular characterization of C/EBPalpha in pancreatic cancer cells.

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Kumagai T, Akagi T, Desmond JC, Kawamata N, Gery S, Imai Y, Song JH, Gui D, Said J, and Koeffler HP

International journal of cancer. Journal international du cancer 124(4):827-33, 2009 Feb 15 - Who cited this? | PubMed ID: 19035457 | Fulltext

Low plasma level of cathelicidin antimicrobial peptide (hCAP18) predicts increased infectious disease mortality in patients undergoing hemodialysis.

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Gombart AF, Bhan I, Borregaard N, Tamez H, Camargo CA, Koeffler HP, and Thadhani R

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 48(4):418-24, 2009 Feb 15 - Who cited this? | PubMed ID: 19133797 | Fulltext

Frequent genomic abnormalities in acute myeloid leukemia/myelodysplastic syndrome with normal karyotype.

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Akagi T, Ogawa S, Dugas M, Kawamata N, Yamamoto G, Nannya Y, Sanada M, Miller CW, Yung A, Schnittger S, Haferlach T, Haferlach C, and Koeffler HP

Haematologica 94(2):213-23, 2009 Feb - Who cited this? | PubMed ID: 19144660 | Fulltext

Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primates.

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Gombart AF, Saito T, and Koeffler HP

BMC genomics 10:321, 2009 - Who cited this? | PubMed ID: 19607716 | Fulltext

Genome-wide loss of heterozygosity and uniparental disomy in BRCA1/2-associated ovarian carcinomas.

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Walsh CS, Ogawa S, Scoles DR, Miller CW, Kawamata N, Narod SA, Koeffler HP, and Karlan BY

Clinical cancer research : an official journal of the American Association for Cancer Research 14(23):7645-51, 2008 Dec 1 - Who cited this? | PubMed ID: 19047089 | Fulltext

Novel acyl sulfonamide LY573636-sodium: Effect on hematopoietic malignant cells.

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Haritunians T, Gueller S, O'Kelly J, Ilaria R, and Koeffler HP

Oncology reports 20(5):1237-42, 2008 Nov - Who cited this? | PubMed ID: 18949427 | Fulltext

Novel Gemini vitamin D(3) analogs have potent antitumor activity.

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Saito T, Okamoto R, Haritunians T, O'Kelly J, Uskokovic M, Maehr H, Marczak S, Jankowski P, Badr R, and Koeffler HP

The Journal of steroid biochemistry and molecular biology 112(1-3):151-6, 2008 Nov - Who cited this? | PubMed ID: 18938245 | Fulltext

Chronic phase of ETV6-ABL1 positive CML responds to imatinib.

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Kawamata N, Dashti A, Lu D, Miller B, Koeffler HP, Schreck R, Moore S, and Ogawa S

Genes, chromosomes & cancer 47(10):919-21, 2008 Oct - Who cited this? | PubMed ID: 18615681 | Fulltext

Double minute chromosomes containing MYB gene and NUP214-ABL1 fusion gene in T-cell leukemia detected by single nucleotide polymorphism DNA microarray and fluorescence in situ hybridization.

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Kawamata N, Zhang L, Ogawa S, Nannya Y, Dashti A, Lu D, Lim S, Schreck R, and Koeffler HP

Leukemia research, 2008 Sep 15 - Who cited this? | PubMed ID: 18799215 | Fulltext

Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme.

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Yin D, Wakimoto N, Xing H, Lu D, Huynh T, Wang X, Black KL, and Koeffler HP

International journal of cancer. Journal international du cancer 123(6):1364-75, 2008 Sep 15 - Who cited this? | PubMed ID: 18561312 | Fulltext

Blockade of mTOR signaling potentiates the ability of histone deacetylase inhibitor to induce growth arrest and differentiation of acute myelogenous leukemia cells.

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Nishioka C, Ikezoe T, Yang J, Koeffler HP, and Yokoyama A

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 2008 Sep 11 - Who cited this? | PubMed ID: 18784743 | Fulltext

Induction of sodium iodide symporter gene and molecular characterisation of HNF3 beta/FoxA2, TTF-1 and C/EBP beta in thyroid carcinoma cells.

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Akagi T, Luong QT, Gui D, Said J, Selektar J, Yung A, Bunce CM, Braunstein GD, and Koeffler HP

British journal of cancer 99(5):781-8, 2008 Sep 2 - Who cited this? | PubMed ID: 18682709 | Fulltext

Nonsteroidal Anti-inflammatory Drugs Suppress Glioma via 15-Hydroxyprostaglandin Dehydrogenase.

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Wakimoto N, Wolf I, Yin D, O'Kelly J, Akagi T, Abramovitz L, Black KL, Tai HH, and Koeffler HP

Cancer research 68(17):6978, 2008 Sep 1 - Who cited this? | PubMed ID: 18757412 | Fulltext

Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer.

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Wolf I, Levanon-Cohen S, Bose S, Ligumsky H, Sredni B, Kanety H, Kuro-o M, Karlan B, Kaufman B, Koeffler HP, and Rubinek T

Oncogene, 2008 Sep 1 - Who cited this? | PubMed ID: 18762812 | Fulltext

Identification of marker genes including RUNX3 (AML2) that discriminate between different myeloproliferative neoplasms and normal individuals.

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Müller CI, Luong QT, Shih LY, Jones LC, Desmond JC, Kawamata N, Tcherniantchouk O, Liu Q, Ito K, Osato M, Ito Y, Tefferi A, de Vos S, and Koeffler HP

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 22(9):1773, 2008 Sep - Who cited this? | PubMed ID: 18323800 | Fulltext

Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells.

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Haritunians T, Gueller S, Zhang L, Badr R, Yin D, Xing H, Fung MC, and Koeffler HP

Leukemia research 32(9):1366, 2008 Sep - Who cited this? | PubMed ID: 18405967 | Fulltext

Genetic profiling of myeloproliferative disorders by single-nucleotide polymorphism oligonucleotide microarray.

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Kawamata N, Ogawa S, Yamamoto G, Lehmann S, Levine RL, Pikman Y, Nannya Y, Sanada M, Miller CW, Gilliland DG, and Koeffler HP

Experimental hematology, 2008 Aug 22 - Who cited this? | PubMed ID: 18723266 | Fulltext

Advances in the treatment of acute myeloid leukemia: from chromosomal aberrations to biologically targeted therapy.

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Lübbert M, Müller-Tidow C, Hofmann WK, and Koeffler HP

Journal of cellular biochemistry 104(6):2059, 2008 Aug 15 - Who cited this? | PubMed ID: 18613031 | Fulltext

Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray.

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Kawamata N, Ogawa S, Zimmermann M, Niebuhr B, Stocking C, Sanada M, Hemminki K, Yamatomo G, Nannya Y, Koehler R, Flohr T, Miller CW, Harbott J, Ludwig WD, Stanulla M, Schrappe M,

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Proceedings of the National Academy of Sciences of the United States of America, 2008 Aug 12 - Who cited this? | PubMed ID: 18697940 | Fulltext

Cucurbitacin B has a potent antiproliferative effect on breast cancer cells in vitro and in vivo.

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Wakimoto N, Yin D, O'Kelly J, Haritunians T, Karlan B, Said J, Xing H, and Koeffler HP

Cancer science, 2008 Jul 7 - Who cited this? | PubMed ID: 18627377 | Fulltext

Functional domains of CCN1 (Cyr61) regulate breast cancer progression.

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O'Kelly J, Chung A, Lemp N, Chumakova K, Yin D, Wang HJ, Said J, Gui D, Miller CW, Karlan BY, and Koeffler HP

International journal of oncology 33(1):59, 2008 Jul - Who cited this? | PubMed ID: 18575751 | Fulltext

Inhibition of MEK/ERK signaling synergistically potentiates histone deacetylase inhibitor-induced growth arrest, apoptosis and acetylation of histone H3 on p21waf1 promoter in acute myelogenous leukemia cell.

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Nishioka C, Ikezoe T, Yang J, Koeffler HP, and Yokoyama A

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 22(7):1449, 2008 Jul - Who cited this? | PubMed ID: 18185526 | Fulltext

Adaptor protein Lnk associates with Y568 in c-Kit.

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Gueller S, Gery S, Nowak V, Liu L, Serve H, and Koeffler HP

The Biochemical journal, 2008 Jun 30 - Who cited this? | PubMed ID: 18588518 | Fulltext

ERCC5 is a novel biomarker of ovarian cancer prognosis.

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Walsh CS, Ogawa S, Karahashi H, Scoles DR, Pavelka JC, Tran H, Miller CW, Kawamata N, Ginther C, Dering J, Sanada M, Nannya Y, Slamon DJ, Koeffler HP, and Karlan BY

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26(18):2952, 2008 Jun 20 - Who cited this? | PubMed ID: 18565881 | Fulltext

Blockade of MEK/ERK signaling enhances sunitinib-induced growth inhibition and apoptosis of leukemia cells possessing activating mutations of the FLT3 gene.

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Nishioka C, Ikezoe T, Yang J, Takeshita A, Taniguchi A, Komatsu N, Togitani K, Koeffler HP, and Yokoyama A

Leukemia research 32(6):865-72, 2008 Jun - Who cited this? | PubMed ID: 17983653 | Fulltext

Ki11502, a novel multitargeted receptor tyrosine kinase inhibitor, induces growth arrest and apoptosis of human leukemia cells in vitro and in vivo.

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Nishioka C, Ikezoe T, Yang J, Miwa A, Tasaka T, Kuwayama Y, Togitani K, Koeffler HP, and Yokoyama A

Blood 111(10):5086-92, 2008 May 15 - Who cited this? | PubMed ID: 18309036 | Fulltext

Molecular allelokaryotyping of early-stage, untreated chronic lymphocytic leukemia.

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Lehmann S, Ogawa S, Raynaud SD, Sanada M, Nannya Y, Ticchioni M, Bastard C, Kawamata N, and Koeffler HP

Cancer 112(6):1296, 2008 Mar 15 - Who cited this? | PubMed ID: 18246537 | Fulltext

Impaired response to GM-CSF and G-CSF, and enhanced apoptosis in C/EBPbeta-deficient hematopoietic cells.

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Akagi T, Saitoh T, O'Kelly J, Akira S, Gombart AF, and Koeffler HP

Blood 111(6):2999, 2008 Mar 15 - Who cited this? | PubMed ID: 18056834 | Fulltext

Negative Feedback Regulation of IFN-{gamma} Pathway by IFN Regulatory Factor 2 in Esophageal Cancers.

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Wang Y, Liu D, Chen P, Koeffler HP, Tong X, and Xie D

Cancer research 68(4):1136-43, 2008 Feb 15 - Who cited this? | PubMed ID: 18281489 | Fulltext

Histone deacetylase inhibitors induce growth arrest and apoptosis of HTLV-1-infected T-cells via blockade of signaling by nuclear factor kappaB.

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Nishioka C, Ikezoe T, Yang J, Komatsu N, Bandobashi K, Taniguchi A, Kuwayama Y, Togitani K, Koeffler HP, and Taguchi H

Leukemia research 32(2):287, 2008 Feb - Who cited this? | PubMed ID: 17644177 | Fulltext

Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray.

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Kawamata N, Ogawa S, Zimmermann M, Kato M, Sanada M, Hemminki K, Yamatomo G, Nannya Y, Koehler R, Flohr T, Miller CW, Harbott J, Ludwig WD, Stanulla M, Schrappe M, Bartram CR,

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Blood 111(2):776, 2008 Jan 15 - Who cited this? | PubMed ID: 17890455 | Fulltext

A Role for the PPARgamma in Cancer Therapy.

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Campbell MJ, Carlberg C, and Koeffler HP

PPAR research 2008:314974, 2008 - Who cited this? | PubMed ID: 18528521 | Fulltext

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