Papers authored by Knick VB

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2,3,5-Trisubstituted pyridines as selective AKT inhibitors-Part I: Substitution at 2-position of the core pyridine for ROCK1 selectivity.
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Lin H, Yamashita DS, Zeng J, Xie R, Wang W, Nidarmarthy S, Luengo JI, Rhodes N, Knick VB, Choudhry AE, Lai Z, Minthorn EA, Strum SL, Wood ER, Elkins PA, Concha NO, 
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Bioorganic & medicinal chemistry letters 20(2):673-8, 2010 Jan 15 - Who cited this? | PubMed ID: 20006497 | Fulltext
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Discovery of thiophene inhibitors of polo-like kinase.
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Emmitte KA, Andrews CW, Badiang JG, Davis-Ward RG, Dickson HD, Drewry DH, Emerson HK, Epperly AH, Hassler DF, Knick VB, Kuntz KW, Lansing TJ, Linn JA, Mook RA, Nailor KE, Salovich JM, 
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Bioorganic & medicinal chemistry letters 19(3):1018-21, 2009 Feb 1 - Who cited this? | PubMed ID: 19097784 | Fulltext
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Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors.
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Stevens KL, Reno MJ, Alberti JB, Price DJ, Kane-Carson LS, Knick VB, Shewchuk LM, Hassell AM, Veal JM, Davis ST, Griffin RJ, and Peel MR
Bioorganic & medicinal chemistry letters 18(21):5758-62, 2008 Nov 1 - Who cited this? | PubMed ID: 18835709 | Fulltext
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Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a Novel Inhibitor of AKT Kinase.
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Heerding DA, Rhodes N, Leber JD, Clark TJ, Keenan RM, Lafrance LV, Li M, Safonov IG, Takata DT, Venslavsky JW, Yamashita DS, Choudhry AE, Copeland RA, Lai Z, Schaber MD, Tummino PJ, 
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Journal of medicinal chemistry 51(18):5663-79, 2008 Sep 25 - Who cited this? | PubMed ID: 18800763 | Fulltext
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Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor.
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Harris PA, Boloor A, Cheung M, Kumar R, Crosby RM, Davis-Ward RG, Epperly AH, Hinkle KW, Hunter RN, Johnson JH, Knick VB, Laudeman CP, Luttrell DK, Mook RA, Nolte RT, Rudolph SK, 
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Journal of medicinal chemistry 51(15):4632-40, 2008 Aug 14 - Who cited this? | PubMed ID: 18620382 | Fulltext
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Characterization of an Akt kinase inhibitor with potent pharmacodynamic and antitumor activity.
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Rhodes N, Heerding DA, Duckett DR, Eberwein DJ, Knick VB, Lansing TJ, McConnell RT, Gilmer TM, Zhang SY, Robell K, Kahana JA, Geske RS, Kleymenova EV, Choudhry AE, Lai Z, Leber JD, 
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Cancer research 68(7):2366-74, 2008 Apr 1 - Who cited this? | PubMed ID: 18381444 | Fulltext
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Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity.
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Kumar R, Knick VB, Rudolph SK, Johnson JH, Crosby RM, Crouthamel MC, Hopper TM, Miller CG, Harrington LE, Onori JA, Mullin RJ, Gilmer TM, Truesdale AT, Epperly AH, Boloor A, Stafford JA, 
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Molecular cancer therapeutics 6(7):2012-21, 2007 Jul - Who cited this? | PubMed ID: 17620431 | Fulltext
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In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1.
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Lansing TJ, McConnell RT, Duckett DR, Spehar GM, Knick VB, Hassler DF, Noro N, Furuta M, Emmitte KA, Gilmer TM, Mook RA, and Cheung M
Molecular cancer therapeutics 6(2):450, 2007 Feb - Who cited this? | PubMed ID: 17267659 | Fulltext
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Discovery of a novel and potent series of dianilinopyrimidineurea and urea isostere inhibitors of VEGFR2 tyrosine kinase.
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Sammond DM, Nailor KE, Veal JM, Nolte RT, Wang L, Knick VB, Rudolph SK, Truesdale AT, Nartey EN, Stafford JA, Kumar R, and Cheung M
Bioorganic & medicinal chemistry letters 15(15):3519-23, 2005 Aug 1 - Who cited this? | PubMed ID: 15990302 | Fulltext
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Retraction.
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Davis ST, Benson BG, Bramson HN, Chapman DE, Dickerson SH, Dold KM, Eberwein DJ, Edelstein M, Frye SV, Gampe RT, Grifffen RJ, Harris PA, Hassell AM, Holmes WD, Hunter RN, Knick VB, 
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Science (New York, N.Y.) 298(5602):2327, 2002 Dec 20 - Who cited this? | PubMed ID: 12526115 | Fulltext
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Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors.
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Davis ST, Benson BG, Bramson HN, Chapman DE, Dickerson SH, Dold KM, Eberwein DJ, Edelstein M, Frye SV, Gampe Jr RT, Griffin RJ, Harris PA, Hassell AM, Holmes WD, Hunter RN, Knick VB, 
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Science (New York, N.Y.) 291(5501):134-7, 2001 Jan 5 - Who cited this? | PubMed ID: 11141566 | Fulltext
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Clinical experience with leucovorin and 5-fluorouracil.
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Laufman LR, Brenckman WD, Stydnicki KA, Morgan ED, Collier M, Knick VB, Duch DS, Mullin R, and Ferone R
Cancer 63(6 Suppl):1031-5, 1989 Mar 15 - Who cited this? | PubMed ID: 2783880 | Fulltext
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Clinical experience with CF-FUra.
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Laufman LR, Brenckman WD, Stydnicki KA, Morgan ED, Collier M, Knick VB, Duch DS, Mullin R, and Ferone R
Advances in experimental medicine and biology 244:201-11, 1988 - Who cited this? | PubMed ID: 3073655 | Fulltext
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Antibacterial activity and mechanism of action of 3'-azido-3'-deoxythymidine (BW A509U).
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Elwell LP, Ferone R, Freeman GA, Fyfe JA, Hill JA, Ray PH, Richards CA, Singer SC, Knick VB, and Rideout JL
Antimicrobial agents and chemotherapy 31(2):274-80, 1987 Feb - Who cited this? | PubMed ID: 3551832 | Fulltext
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In vitro and in vivo efficacy of the combination trimethoprim-sulfamethoxazole against clinical isolates of methicillin-resistant Staphylococcus aureus.
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Elwell LP, Wilson HR, Knick VB, and Keith BR
Antimicrobial agents and chemotherapy 29(6):1092-4, 1986 Jun - Who cited this? | PubMed ID: 3488022 | Fulltext
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