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Papers authored by Kirby GM

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Expression of cytochrome P450 2A5 in a glucose-6-phosphate dehydrogenase-deficient mouse model of oxidative stress.

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Nichols KD and Kirby GM

Biochemical pharmacology 75(5):1230-9, 2008 Mar 1 - Who cited this? | PubMed ID: 18068688 | Fulltext

Dexamethasone-Mediated Up-Regulation of Human CYP2A6 Involves the Glucocorticoid Receptor and Increased Binding of Hepatic Nuclear Factor 4{alpha} to the Proximal Promoter.

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Onica T, Nichols K, Larin M, Ng L, Maslen A, Dvorak Z, Pascussi JM, Vilarem MJ, Maurel P, and Kirby GM

Molecular pharmacology 73(2):451-60, 2008 Feb - Who cited this? | PubMed ID: 17978169 | Fulltext

Microarray analysis of hepatic gene expression in pyrazole-mediated hepatotoxicity: Identification of potential stimuli of Cyp2a5 induction.

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Nichols KD and Kirby GM

Biochemical pharmacology 75(2):538-51, 2008 Jan 15 - Who cited this? | PubMed ID: 17945193 | Fulltext

Proteomic analysis of ovomucoid hypersensitivity in mice by two-dimensional difference gel electrophoresis (2D-DIGE).

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Hobson DJ, Rupa P, Diaz GJ, Zhang H, Yang M, Mine Y, Turner PV, and Kirby GM

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 45(12):2372-80, 2007 Dec - Who cited this? | PubMed ID: 17897766 | Fulltext

Repression of human GSTA1 by interleukin-1beta is mediated by variant hepatic nuclear factor-1C.

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Ng L, Nichols K, O'Rourke K, Maslen A, and Kirby GM

Molecular pharmacology 71(1):201-8, 2007 Jan - Who cited this? | PubMed ID: 17021248 | Fulltext

Chemical inducers of rodent glutathione s-transferases down-regulate human GSTA1 transcription through a mechanism involving variant hepatic nuclear factor 1-C.

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Romero L, Ng L, and Kirby GM

Molecular pharmacology 70(1):277, 2006 Jul - Who cited this? | PubMed ID: 16608922 | Fulltext

Gender-dependent reductions in vertebrae length, bone mineral density and content by doxorubicin are not reduced by dexrazoxane in young rats: effect on growth plate and intervertebral discs.

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Mwale F, Antoniou J, Héon S, Servant N, Wang C, Kirby GM, Demers CN, and Chalifour LE

Calcified tissue international 76(3):214-21, 2005 Mar - Who cited this? | PubMed ID: 15570399 | Fulltext

Endoplasmic reticulum stress due to altered cellular redox status positively regulates murine hepatic CYP2A5 expression.

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Gilmore WJ and Kirby GM

The Journal of pharmacology and experimental therapeutics 308(2):600-8, 2004 Feb - Who cited this? | PubMed ID: 14610226 | Fulltext

Dexrazoxane does not protect against doxorubicin-induced damage in young rats.

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Héon S, Bernier M, Servant N, Dostanic S, Wang C, Kirby GM, Alpert L, and Chalifour LE

American journal of physiology. Heart and circulatory physiology 285(2):H499-506, 2003 Aug - Who cited this? | PubMed ID: 12714334 | Fulltext

Effects of lipopolysaccharide-stimulated inflammation and pyrazole-mediated hepatocellular injury on mouse hepatic Cyp2a5 expression.

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Gilmore WJ, Hartmann G, Piquette-Miller M, Marriott J, and Kirby GM

Toxicology 184(2-3):211-26, 2003 Mar 3 - Who cited this? | PubMed ID: 12499123 | Fulltext

Down-regulation of alpha class glutathione S-transferase by interleukin-1beta in human intestinal epithelial cells (Caco-2) in culture.

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Romero L, Higgins MA, Gilmore J, Boudreau K, Maslen A, Barker HJ, and Kirby GM

Drug metabolism and disposition: the biological fate of chemicals 30(11):1186-93, 2002 Nov - Who cited this? | PubMed ID: 12386123 | Fulltext

Loss of glutathione S-transferase (GST) mu phenotype in colorectal adenocarcinomas from patients with a GSTM1 positive genotype.

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Barker HJ, Alpert LC, Compton CC, Maslen A, and Kirby GM

Cancer letters 177(1):65-74, 2002 Mar 8 - Who cited this? | PubMed ID: 11809532 | Fulltext

Identification of a 43-kDa protein in human liver cytosol that binds to the 3'-untranslated region of CYP2A6 mRNA.

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Gilmore J, Rotondo F, Pelletier AM, LaMarre J, Alaoui-Jamali M, and Kirby GM

Biochemical pharmacology 62(6):669-78, 2001 Sep 15 - Who cited this? | PubMed ID: 11551511 | Fulltext

Diminished molecular response to doxorubicin and loss of cardioprotective effect of dexrazoxane in Egr-1 deficient female mice.

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Saadane N, Yue P, Alpert L, Mitmaker B, Kirby GM, and Chalifour LE

Canadian journal of physiology and pharmacology 79(6):533-44, 2001 Jun - Who cited this? | PubMed ID: 11430591 | Fulltext

Allele-specific PCR analysis of p53 codon 249 AGT transversion in liver tissues from patients with viral hepatitis.

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Kirby GM, Batist G, Fotouhi-Ardakani N, Nakazawa H, Yamasaki H, Kew M, Cameron RG, and Alaoui-Jamali MA

International journal of cancer. Journal international du cancer 68(1):21-5, 1996 Sep 27 - Who cited this? | PubMed ID: 8895534 | Fulltext

Overexpression of cytochrome P-450 isoforms involved in aflatoxin B1 bioactivation in human liver with cirrhosis and hepatitis.

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Kirby GM, Batist G, Alpert L, Lamoureux E, Cameron RG, and Alaoui-Jamali MA

Toxicologic pathology 24(4):458-67, 1996 - Who cited this? | PubMed ID: 8864187 | Fulltext

Influences of chronic cholangiohepatitis and cholestasis on hepatic metabolism of benzo[a]pyrene in white suckers (Catostomus commersoni) from industrially polluted areas of Lake Ontario.

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Kirby GM, Stalker MJ, Gordon S, Quinn BA, van Schooten FJ, and Hayes MA

Carcinogenesis 16(12):2923-9, 1995 Dec - Who cited this? | PubMed ID: 8603465 | Fulltext

Enhanced hexachloro-1:3-butadiene nephrotoxicity in rats with a preexisting adriamycin-induced nephrotic syndrome.

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Kirby GM and Bach PH

Toxicologic pathology 23(3):303-12, 1995 - Who cited this? | PubMed ID: 7659954 | Fulltext

Metabolism of nitrosamines and aflatoxin B1 by hamster liver CYP2A enzymes.

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Pelkonen P, Kirby GM, Wild CP, Bartsch H, and Lang MA

Chemico-biological interactions 93(1):41-50, 1994 Oct - Who cited this? | PubMed ID: 8069948 | Fulltext

Induction of specific cytochrome P450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice.

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Kirby GM, Chemin I, Montesano R, Chisari FV, Lang MA, and Wild CP

Molecular carcinogenesis 11(2):74-80, 1994 Oct - Who cited this? | PubMed ID: 7916995 | Fulltext

Association of liver fluke (Opisthorchis viverrini) infestation with increased expression of cytochrome P450 and carcinogen metabolism in male hamster liver.

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Kirby GM, Pelkonen P, Vatanasapt V, Camus AM, Wild CP, and Lang MA

Molecular carcinogenesis 11(2):81-9, 1994 Oct - Who cited this? | PubMed ID: 7916996 | Fulltext

In vitro metabolism of aflatoxin B1 by normal and tumorous liver tissue from Thailand.

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Kirby GM, Wolf CR, Neal GE, Judah DJ, Henderson CJ, Srivatanakul P, and Wild CP

Carcinogenesis 14(12):2613-20, 1993 Dec - Who cited this? | PubMed ID: 8269634 | Fulltext

Loss of glutathione S-transferases in pollution-associated liver neoplasms in white suckers (Catostomus commersoni) from Lake Ontario.

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Stalker MJ, Kirby GM, Kocal TE, Smith IR, and Hayes MA

Carcinogenesis 12(12):2221-6, 1991 Dec - Who cited this? | PubMed ID: 1660792 | Fulltext

Expression of immunoreactive glutathione S-transferases in hepatic neoplasms induced by aflatoxin B1 or 1,2-dimethylbenzanthracene in rainbow trout (Oncorhynchus mykiss).

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Kirby GM, Stalker M, Metcalfe C, Kocal T, Ferguson H, and Hayes MA

Carcinogenesis 11(12):2255-7, 1990 Dec - Who cited this? | PubMed ID: 1702371 | Fulltext

The role of glutathione S-transferases in the hepatic metabolism of benzo[a]pyrene in white suckers (Catostomus commersoni) from polluted and reference sites in the Great Lakes.

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Kirby GM, Bend JR, Smith IR, and Hayes MA

Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 95(1):25-30, 1990 - Who cited this? | PubMed ID: 1971553 | Fulltext

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