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Papers authored by Keats J

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Spontaneous remission in a patient with t(4;14) translocation multiple myeloma.

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Puig N, Trudel S, Keats JJ, Li ZH, Braggio E, Ahmann GJ, Zeng S, Fonseca R, and Kukreti V

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(33):e194-7, 2009 Nov 20 - Who cited this? | PubMed ID: 19805681 | Fulltext

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance.

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O'Hare T, Shakespeare WC, Zhu X, Eide CA, Rivera VM, Wang F, Adrian LT, Zhou T, Huang WS, Xu Q, Metcalf CA, Tyner JW, Loriaux MM, Corbin AS, Wardwell S, Ning Y,

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Cancer cell 16(5):401-12, 2009 Nov 6 - Who cited this? | PubMed ID: 19878872 | Fulltext

Rearrangements and amplification of IER3 (IEX-1) represent a novel and recurrent molecular abnormality in myelodysplastic syndromes.

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Steensma DP, Neiger JD, Porcher JC, Keats JJ, Bergsagel PL, Dennis TR, Knudson RA, Jenkins RB, Santana-Davila R, Kumar R, and Ketterling RP

Cancer research 69(19):7518-23, 2009 Oct 1 - Who cited this? | PubMed ID: 19773435 | Fulltext

The start of everything.

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Musser G, Rusting R, Wong K, Nicholson C, Castelvecchi D, Soares C, Grierson B, Sachs JS, Moyer M, Collins GP, Brown P, Stix G, Wenner M, Hvistendahl M, Yam P, and Keats J

Scientific American 301(3):70-94, 96-98, 100, 2009 Sep - Who cited this? | PubMed ID: 19708530 | Fulltext

9-(Arenethenyl)purines as dual Src/Abl kinase inhibitors targeting the inactive conformation: design, synthesis, and biological evaluation.

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Huang WS, Zhu X, Wang Y, Azam M, Wen D, Sundaramoorthi R, Thomas RM, Liu S, Banda G, Lentini SP, Das S, Xu Q, Keats J, Wang F, Wardwell S, Ning Y,

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Journal of medicinal chemistry 52(15):4743-56, 2009 Aug 13 - Who cited this? | PubMed ID: 19572547 | Fulltext

Identification of a potent natural triterpenoid inhibitor of proteosome chymotrypsin-like activity and NF-kappaB with antimyeloma activity in vitro and in vivo.

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Tiedemann RE, Schmidt J, Keats JJ, Shi CX, Zhu YX, Palmer SE, Mao X, Schimmer AD, and Stewart AK

Blood 113(17):4027-37, 2009 Apr 23 - Who cited this? | PubMed ID: 19096011 | Fulltext

Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-kappaB signaling pathways in Waldenstrom's macroglobulinemia.

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Braggio E, Keats JJ, Leleu X, Van Wier S, Jimenez-Zepeda VH, Valdez R, Schop RF, Price-Troska T, Henderson K, Sacco A, Azab F, Greipp P, Gertz M, Hayman S, Rajkumar SV, Carpten J,

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Cancer research 69(8):3579-88, 2009 Apr 15 - Who cited this? | PubMed ID: 19351844 | Fulltext

High-Resolution Genomic Analysis in Waldenström's Macroglobulinemia Identifies Disease-Specific and Common Abnormalities with Marginal Zone Lymphomas.

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Braggio E, Keats JJ, Leleu X, Wier SV, Jimenez-Zepeda VH, Schop RF, Chesi M, Barrett M, Stewart AK, Dogan A, Bergsagel PL, Ghobrial IM, and Fonseca R

Clinical lymphoma & myeloma 9(1):39-42, 2009 Feb - Who cited this? | PubMed ID: 19362969 | Fulltext

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.

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Vallabhapurapu S, Matsuzawa A, Zhang W, Tseng PH, Keats JJ, Wang H, Vignali DA, Bergsagel PL, and Karin M

Nature immunology 9(12):1364-70, 2008 Dec - Who cited this? | PubMed ID: 18997792 | Fulltext

Novel N9-arenethenyl purines as potent dual Src/Abl tyrosine kinase inhibitors.

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Wang Y, Shakespeare WC, Huang WS, Sundaramoorthi R, Lentini S, Das S, Liu S, Banda G, Wen D, Zhu X, Xu Q, Keats J, Wang F, Wardwell S, Ning Y, Snodgrass JT,

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Bioorganic & medicinal chemistry letters 18(17):4907-12, 2008 Sep 1 - Who cited this? | PubMed ID: 18691885 | Fulltext

Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2.

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Arendt BK, Ramirez-Alvarado M, Sikkink LA, Keats JJ, Ahmann GJ, Dispenzieri A, Fonseca R, Ketterling RP, Knudson RA, Mulvihill EM, Tschumper RC, Wu X, Zeldenrust SR, and Jelinek DF

Blood, 2008 Jun 20 - Who cited this? | PubMed ID: 18567838 | Fulltext

Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells.

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Evans R, Naber C, Steffler T, Checkland T, Keats J, Maxwell C, Perry T, Chau H, Belch A, Pilarski L, and Reiman T

Leukemia & lymphoma 49(3):559, 2008 Mar - Who cited this? | PubMed ID: 18297535 | Fulltext

The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma.

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Evans RP, Naber C, Steffler T, Checkland T, Maxwell CA, Keats JJ, Belch AR, Pilarski LM, Lai R, and Reiman T

British journal of haematology 140(3):295-302, 2008 Feb - Who cited this? | PubMed ID: 18076711 | Fulltext

SAR of carbon-linked, 2-substituted purines: synthesis and characterization of AP23451 as a novel bone-targeted inhibitor of Src tyrosine kinase with in vivo anti-resorptive activity.

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Shakespeare WC, Wang Y, Bohacek R, Keenan T, Sundaramoorthi R, Metcalf C, Dilauro A, Roeloffzen S, Liu S, Saltmarsh J, Paramanathan G, Dalgarno D, Narula S, Pradeepan S, van Schravendijk MR, Keats J,

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Chemical biology & drug design 71(2):97-105, 2008 Feb - Who cited this? | PubMed ID: 18179464 | Fulltext

Diagnostic evaluation of t(4;14) in multiple myeloma and evidence for clonal evolution.

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Stewart AK, Chang H, Trudel S, Anderson KC, Richardson P, Alsina M, Reece D, Young S, Sable-Hunt A, Li Z, Keats J, Van Wier S, Ahmann G, Price-Troska T, Giusti K, Bergsagel PL,

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Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 21(11):2358-9, 2007 Nov - Who cited this? | PubMed ID: 17568814 | Fulltext

Crystal structure of the T315I mutant of AbI kinase.

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Zhou T, Parillon L, Li F, Wang Y, Keats J, Lamore S, Xu Q, Shakespeare W, Dalgarno D, and Zhu X

Chemical biology & drug design 70(3):171-81, 2007 Sep - Who cited this? | PubMed ID: 17718712 | Fulltext

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

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Keats JJ, Fonseca R, Chesi M, Schop R, Baker A, Chng WJ, Van Wier S, Tiedemann R, Shi CX, Sebag M, Braggio E, Henry T, Zhu YX, Fogle H, Price-Troska T, Ahmann G,

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Cancer cell 12(2):131, 2007 Aug - Who cited this? | PubMed ID: 17692805 | Fulltext

Ten years and counting: so what do we know about t(4;14)(p16;q32) multiple myeloma.

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Keats JJ, Reiman T, Belch AR, and Pilarski LM

Leukemia & lymphoma 47(11):2289-300, 2006 Nov - Who cited this? | PubMed ID: 17107900 | Fulltext

Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds.

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Dalgarno D, Stehle T, Narula S, Schelling P, van Schravendijk MR, Adams S, Andrade L, Keats J, Ram M, Jin L, Grossman T, MacNeil I, Metcalf C, Shakespeare W, Wang Y, Keenan T,

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Chemical biology & drug design 67(1):46-57, 2006 Jan - Who cited this? | PubMed ID: 16492148 | Fulltext

AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes.

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Summy JM, Trevino JG, Lesslie DP, Baker CH, Shakespeare WC, Wang Y, Sundaramoorthi R, Metcalf CA, Keats JA, Sawyer TK, and Gallick GE

Molecular cancer therapeutics 4(12):1900, 2005 Dec - Who cited this? | PubMed ID: 16373705 | Fulltext

Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients.

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Keats JJ, Maxwell CA, Taylor BJ, Hendzel MJ, Chesi M, Bergsagel PL, Larratt LM, Mant MJ, Reiman T, Belch AR, and Pilarski LM

Blood 105(10):4060-9, 2005 May 15 - Who cited this? | PubMed ID: 15677557 | Fulltext

Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity.

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Maxwell CA, Keats JJ, Belch AR, Pilarski LM, and Reiman T

Cancer research 65(3):850-60, 2005 Feb 1 - Who cited this? | PubMed ID: 15705883 | Fulltext

SSX cancer testis antigens are expressed in most multiple myeloma patients: co-expression of SSX1, 2, 4, and 5 correlates with adverse prognosis and high frequencies of SSX-positive PCs.

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Taylor BJ, Reiman T, Pittman JA, Keats JJ, de Bruijn DR, Mant MJ, Belch AR, and Pilarski LM

Journal of immunotherapy (Hagerstown, Md. : 1997) 28(6):564-75, 2005 - Who cited this? | PubMed ID: 16224274 | Fulltext

Inhibition of wild-type and mutant Bcr-Abl by AP23464, a potent ATP-based oncogenic protein kinase inhibitor: implications for CML.

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O'Hare T, Pollock R, Stoffregen EP, Keats JA, Abdullah OM, Moseson EM, Rivera VM, Tang H, Metcalf CA, Bohacek RS, Wang Y, Sundaramoorthi R, Shakespeare WC, Dalgarno D, Clackson T, Sawyer TK,

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Blood 104(8):2532, 2004 Oct 15 - Who cited this? | PubMed ID: 15256422 | Fulltext

RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma.

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Maxwell CA, Rasmussen E, Zhan F, Keats JJ, Adamia S, Strachan E, Crainie M, Walker R, Belch AR, Pilarski LM, Barlogie B, Shaughnessy J, and Reiman T

Blood 104(4):1151-8, 2004 Aug 15 - Who cited this? | PubMed ID: 15105292 | Fulltext

Bone-targeted Src kinase inhibitors: novel pyrrolo- and pyrazolopyrimidine analogues.

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Sundaramoorthi R, Shakespeare WC, Keenan TP, Metcalf CA, Wang Y, Mani U, Taylor M, Liu S, Bohacek RS, Narula SS, Dalgarno DC, van Schravandijk MR, Violette SM, Liou S, Adams S, Ram MK,

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Bioorganic & medicinal chemistry letters 13(18):3063-6, 2003 Sep 15 - Who cited this? | PubMed ID: 12941334 | Fulltext

Bone-targeted 2,6,9-trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases.

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Wang Y, Metcalf CA, Shakespeare WC, Sundaramoorthi R, Keenan TP, Bohacek RS, van Schravendijk MR, Violette SM, Narula SS, Dalgarno DC, Haraldson C, Keats J, Liou S, Mani U, Pradeepan S, Ram M,

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Bioorganic & medicinal chemistry letters 13(18):3067-70, 2003 Sep 15 - Who cited this? | PubMed ID: 12941335 | Fulltext

Bone-targeted pyrido[2,3-d]pyrimidin-7-ones: potent inhibitors of Src tyrosine kinase as novel antiresorptive agents.

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Vu CB, Luke GP, Kawahata N, Shakespeare WC, Wang Y, Sundaramoorthi R, Metcalf CA, Keenan TP, Pradeepan S, Corpuz E, Merry T, Bohacek RS, Dalgarno DC, Narula SS, van Schravendijk MR, Ram MK,

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Bioorganic & medicinal chemistry letters 13(18):3071-4, 2003 Sep 15 - Who cited this? | PubMed ID: 12941336 | Fulltext

RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability.

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Maxwell CA, Keats JJ, Crainie M, Sun X, Yen T, Shibuya E, Hendzel M, Chan G, and Pilarski LM

Molecular biology of the cell 14(6):2262, 2003 Jun - Who cited this? | PubMed ID: 12808028 | Fulltext

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression.

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Keats JJ, Reiman T, Maxwell CA, Taylor BJ, Larratt LM, Mant MJ, Belch AR, and Pilarski LM

Blood 101(4):1520-9, 2003 Feb 15 - Who cited this? | PubMed ID: 12393535 | Fulltext

Leukemic B cells clonally identical to myeloma plasma cells are myelomagenic in NOD/SCID mice.

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Pilarski LM, Seeberger K, Coupland RW, Eshpeter A, Keats JJ, Taylor BJ, and Belch AR

Experimental hematology 30(3):221-8, 2002 Mar - Who cited this? | PubMed ID: 11882359 | Fulltext

Evaluating the effects of a peer support programme on adolescents' knowledge, attitudes and use of alcohol and tobacco.

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Webster RA, Hunter M, and Keats JA

Drug and alcohol review 21(1):7-16, 2002 Mar - Who cited this? | PubMed ID: 12219738 | Fulltext

Patient comfort rounds are an excellent idea.

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Keats J

British journal of nursing (Mark Allen Publishing) 11(8):530, 2002 - Who cited this? | PubMed ID: 12019527 | Fulltext

VIII International Myeloma Workshop, Banff Springs Hotel, Banff, Alberta, Canada, 4-8 May 2001.

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Reiman T and Keats J

European journal of haematology 67(3):199-202, 2001 Sep - Who cited this? | PubMed ID: 11737255 | Fulltext

Paying the piper--calling the tune?.

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Keats J and Rothwell H

Midwives : official journal of the Royal College of Midwives 110(1314):162, 1997 Jul - Who cited this? | PubMed ID: 9256758 | Fulltext

Wales shows the way.

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Keats J

Modern midwife 5(9):28-9, 1995 Sep - Who cited this? | PubMed ID: 7552441 | Fulltext

Personality and sociodemographic influences on adolescents' substance use: a path analysis.

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Webster RA, Hunter M, and Keats JA

The International journal of the addictions 29(7):941-56, 1994 May - Who cited this? | PubMed ID: 8050836 | Fulltext

Peer and parental influences on adolescents' substance use: a path analysis.

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Webster RA, Hunter M, and Keats JA

The International journal of the addictions 29(5):647-57, 1994 Apr - Who cited this? | PubMed ID: 8034377 | Fulltext

Mapping the Friedreich ataxia locus (FRDA) by linkage disequilibrium analysis with highly polymorphic microsatellites.

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Sirugo G, Duclos F, Fujita R, Keats JB, Pandolfo M, Mandel JL, and Koenig M

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 48(5-6):219-24, 1994 - Who cited this? | PubMed ID: 7999982 | Fulltext

The team approach to giving midwifery care for the 1990s.

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Keats J

Midwives chronicle 106(1261):46-8, 1993 Feb - Who cited this? | PubMed ID: 8469186 | Fulltext

Tom.

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Keats J

Midwives chronicle 101(1211):378-80, 1988 Dec - Who cited this? | PubMed ID: 3060703 | Fulltext

Intravenous cholangiography and sonography in acute cholecystitis: prospective evaluation.

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Sherman M, Ralls PW, Quinn M, Halls J, and Keats JB

AJR. American journal of roentgenology 135(2):311-3, 1980 Aug - Who cited this? | PubMed ID: 6773333 | Fulltext

Nonketotic hyperglycinemia. Effects of therapy with strychnine.

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Warburton D, Boyle RJ, Keats JP, Vohr B, Peuschel S, and Oh W

American journal of diseases of children (1960) 134(3):273-5, 1980 Mar - Who cited this? | PubMed ID: 6767393 | Fulltext

Primary meningococcal pericarditis complicated by acute renal failure.

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Jones RH, Shuhaiber H, Noble C, Keats J, and Parsons V

Thorax 34(5):688-9, 1979 Oct - Who cited this? | PubMed ID: 515995 | Fulltext

Test theory.

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Keats JA

Annual review of psychology 18:217-38, 1967 - Who cited this? | PubMed ID: 5333423 | Fulltext

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