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Papers authored by Kanesaka M

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Discovery of trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H),1'-cyclohexane]-4'-carboxamide, a potent and orally active neuropeptide Y Y5 receptor antagonist.

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Haga Y, Sakamoto T, Shibata T, Nonoshita K, Ishikawa M, Suga T, Takahashi H, Takahashi T, Takahashi H, Ando M, Murai T, Gomori A, Oda Z, Kitazawa H, Mitobe Y, Kanesaka M,

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Bioorganic & medicinal chemistry 17(19):6971-82, 2009 Oct 1 - Who cited this? | PubMed ID: 19720539 | Fulltext

Synthesis, structure-activity relationships, and biological profiles of a dihydrobenzoxathiin class of histamine H(3) receptor inverse agonists.

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Sasaki T, Takahashi T, Nagase T, Mizutani T, Ito S, Mitobe Y, Miyamoto Y, Kanesaka M, Yoshimoto R, Tanaka T, Takenaga N, Tokita S, and Sato N

Bioorganic & medicinal chemistry letters 19(15):4232-6, 2009 Aug 1 - Who cited this? | PubMed ID: 19520574 | Fulltext

Synthesis and evaluation of a novel 2-azabicyclo[2.2.2]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

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Sasaki T, Nagase T, Takahashi T, Nagumo A, Shimamura K, Miyamoto Y, Kitazawa H, Kanesaka M, Yoshimoto R, Aragane K, Tokita S, and Sato N

Bioorganic & medicinal chemistry 17(15):5639-47, 2009 Aug 1 - Who cited this? | PubMed ID: 19596583 | Fulltext

Synthesis and biological evaluation of a novel 3-sulfonyl-8-azabicyclo[3.2.1]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

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Nagase T, Takahashi T, Sasaki T, Nagumo A, Shimamura K, Miyamoto Y, Kitazawa H, Kanesaka M, Yoshimoto R, Aragane K, Tokita S, and Sato N

Journal of medicinal chemistry 52(14):4111-4, 2009 Jul 23 - Who cited this? | PubMed ID: 19522500 | Fulltext

5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a Potent Inhibitor for Mammalian Elongase of Long-Chain Fatty Acids Family 6: Examination of Its Potential Utility as a Pharmacological Tool.

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Shimamura K, Kitazawa H, Miyamoto Y, Kanesaka M, Nagumo A, Yoshimoto R, Aragane K, Morita N, Ohe T, Takahashi T, Nagase T, Sato N, and Tokita S

The Journal of pharmacology and experimental therapeutics 330(1):249-56, 2009 Jul - Who cited this? | PubMed ID: 19359527 | Fulltext

Synthesis and evaluation of a novel indoledione class of long chain fatty acid elongase 6 (ELOVL6) inhibitors.

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Takahashi T, Nagase T, Sasaki T, Nagumo A, Shimamura K, Miyamoto Y, Kitazawa H, Kanesaka M, Yoshimoto R, Aragane K, Tokita S, and Sato N

Journal of medicinal chemistry 52(10):3142-5, 2009 May 28 - Who cited this? | PubMed ID: 19388647 | Fulltext

Design, syntheses, and structure-activity relationships of novel NPY Y5 receptor antagonists: 2-{3-Oxospiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl}benzimidazole derivatives.

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Ogino Y, Ohtake N, Nagae Y, Matsuda K, Moriya M, Suga T, Ishikawa M, Kanesaka M, Mitobe Y, Ito J, Kanno T, Ishihara A, Iwaasa H, Ohe T, Kanatani A, and Fukami T

Bioorganic & medicinal chemistry letters 18(18):5010-4, 2008 Sep 15 - Who cited this? | PubMed ID: 18723347 | Fulltext

Syntheses and structure-activity relationships of novel, potent, and selective trans-2-[3-oxospiro[isobenzofuran-1(3H),1'-cyclohexan]-4'-yl]benzimidazole NPY Y5 receptor antagonists.

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Ogino Y, Ohtake N, Nagae Y, Matsuda K, Ishikawa M, Moriya M, Kanesaka M, Mitobe Y, Ito J, Kanno T, Ishihara A, Iwaasa H, Ohe T, Kanatani A, and Fukami T

Bioorganic & medicinal chemistry letters 18(18):4997-5001, 2008 Sep 15 - Who cited this? | PubMed ID: 18752943 | Fulltext

Development of a potent and selective GPR7 (NPBW1) agonist: a systematic structure-activity study of neuropeptide B.

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Kanesaka M, Matsuda M, Hirano A, Tanaka K, Kanatani A, and Tokita S

Journal of peptide science : an official publication of the European Peptide Society 13(6):379-85, 2007 Jun - Who cited this? | PubMed ID: 17486669 | Fulltext

Blockade of body weight gain and plasma corticosterone levels in Zucker fatty rats using an orally active neuropeptide Y Y1 antagonist.

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Ishihara A, Kanatani A, Okada M, Hidaka M, Tanaka T, Mashiko S, Gomori A, Kanno T, Hata M, Kanesaka M, Tominaga Y, Sato NA, Kobayashi M, Murai T, Watanabe K, Ishii Y,

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British journal of pharmacology 136(3):341-6, 2002 Jun - Who cited this? | PubMed ID: 12023935 | Fulltext

[Effect of water on toothbrush bristle stiffness].

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Naganuma S, Kanesaka M, Seki Y, Rokukawa Y, and Omori T

Shigaku. Odontology; journal of Nippon Dental College 55(1):43-8, 1967 Jun - Who cited this? | PubMed ID: 5238163 | Fulltext

[Stiffness of individual toothbrush bristles].

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Kanesaka M, Seki Y, Rokukawa Y, Omori T, and Naganuma S

Shigaku. Odontology; journal of Nippon Dental College 55(1):49-54, 1967 Jun - Who cited this? | PubMed ID: 5238164 | Fulltext

[Reevaluation of homosulfamin (Marfanil) as a topical medication].

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Kanesaka M

Shigaku. Odontology; journal of Nippon Dental College 54(4):343-62, 1967 Mar - Who cited this? | PubMed ID: 4867772 | Fulltext

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