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Papers authored by Kakumu S

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Distribution of hepatitis B virus genotypes among patients with chronic infection in Japan shifting toward an increase of genotype A.

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Matsuura K, Tanaka Y, Hige S, Yamada G, Murawaki Y, Komatsu M, Kuramitsu T, Kawata S, Tanaka E, Izumi N, Okuse C, Kakumu S, Okanoue T, Hino K, Hiasa Y, Sata M,

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Journal of clinical microbiology 47(5):1476-83, 2009 May - Who cited this? | PubMed ID: 19297602 | Fulltext

Inflammatory cytokines modulate chemokine production patterns of HepG2 cells toward initially inclined direction.

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Ohashi T, Tanabe J, Ishikawa T, Okumura A, Sato K, Ayada M, Hotta N, Kuzuya T, Ito H, Nakao H, Yoneda M, and Kakumu S

Hepatology research : the official journal of the Japan Society of Hepatology 39(5):510-9, 2009 May - Who cited this? | PubMed ID: 19207593 | Fulltext

Usefulness of radiofrequency ablation with micro-convex probe for hepatocellular carcinoma.

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Hotta N, Ayada M, Matsumoto E, Okumura A, Ishikawa T, Sato K, Oohashi T, and Kakumu S

Hepato-gastroenterology 56(93):1127-32, 2009 - Who cited this? | PubMed ID: 19760955 | Fulltext

Changes in intrahepatic gene expression profiles from chronic hepatitis to hepatocellular carcinoma in patients with hepatitis C virus infection.

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Furuta K, Sato S, Yamauchi T, and Kakumu S

Hepatology research : the official journal of the Japan Society of Hepatology 38(7):673-82, 2008 Jul - Who cited this? | PubMed ID: 18328064 | Fulltext

Deficiency of forkhead box P3 and cytotoxic T-lymphocyte-associated antigen-4 gene expressions and impaired suppressor function of CD4CD25 T cells in patients with autoimmune hepatitis.

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Okumura A, Ishikawa T, Sato S, Yamauchi T, Oshima H, Ohashi T, Sato K, Ayada M, Hotta N, and Kakumu S

Hepatology research : the official journal of the Japan Society of Hepatology, 2008 Jun 19 - Who cited this? | PubMed ID: 18624718 | Fulltext

Role of V{alpha}14+ NKT cells in the development of Hepatitis B virus-specific CTL: activation of V{alpha}14+ NKT cells promotes the breakage of CTL tolerance.

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Ito H, Ando K, Ishikawa T, Nakayama T, Taniguchi M, Saito K, Imawari M, Moriwaki H, Yokochi T, Kakumu S, and Seishima M

International immunology, 2008 May 16 - Who cited this? | PubMed ID: 18487227 | Fulltext

Early decline of hemoglobin can predict progression of hemolytic anemia during pegylated interferon and ribavirin combination therapy in patients with chronic hepatitis C.

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Hiramatsu N, Kurashige N, Oze T, Takehara T, Tamura S, Kasahara A, Oshita M, Katayama K, Yoshihara H, Imai Y, Kato M, Kawata S, Tsubouchi H, Kumada H, Okanoue T, Kakumu S,

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Hepatology research : the official journal of the Japan Society of Hepatology 38(1):52-9, 2008 Jan - Who cited this? | PubMed ID: 17714473 | Fulltext

Intrahepatic gene expression profiles in chronic hepatitis B and autoimmune liver disease.

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Furuta K, Sato S, Yamauchi T, Ozawa T, Harada M, and Kakumu S

Journal of gastroenterology 43(11):866-74, 2008 - Who cited this? | PubMed ID: 19012040 | Fulltext

Expression of Toll-like receptors in chronic hepatitis C virus infection.

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Sato K, Ishikawa T, Okumura A, Yamauchi T, Sato S, Ayada M, Matsumoto E, Hotta N, Oohashi T, Fukuzawa Y, and Kakumu S

Journal of gastroenterology and hepatology 22(10):1627-32, 2007 Oct - Who cited this? | PubMed ID: 17845690 | Fulltext

Use of hepatitis B vaccine for the treatment of chronic hepatitis B.

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Ishikawa T and Kakumu S

Hepatology research : the official journal of the Japan Society of Hepatology 37 Suppl 3:S347-50, 2007 Oct - Who cited this? | PubMed ID: 17931185 | Fulltext

Double filtration plasmapheresis and interferon combination therapy for chronic hepatitis C patients with genotype 1 and high viral load.

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Fujiwara K, Kaneko S, Kakumu S, Sata M, Hige S, Tomita E, Mochida S, and The Virus Reduction Therapy Study Group

Hepatology research : the official journal of the Japan Society of Hepatology 37(9):701-10, 2007 Sep - Who cited this? | PubMed ID: 17573947 | Fulltext

Combination therapy with lamivudine and HB vaccine on chronic hepatitis B.

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Ishikawa T and Kakumu S

Hepatology research : the official journal of the Japan Society of Hepatology 37(s1):S62-6, 2007 Jul - Who cited this? | PubMed ID: 17627638 | Fulltext

Noninvasive assessment of liver disease - measurement of hepatic fibrosis using tissue strain imaging.

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Hotta N, Ayada M, Okumura A, Ishikawa T, Sato K, Oohashi T, Hijikata Y, Murayama S, Ido M, and Kakumu S

Clinical imaging 31(2):87-92, 2007 - Who cited this? | PubMed ID: 17320774 | Fulltext

Usefulness of live 3D echocardiography during radiofrequency ablation in a case of hepatocellular carcinoma.

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Hotta N, Ayada M, Okumura A, Ishikawa T, and Kakumu S

Clinical imaging 31(4):283-6, 2007 - Who cited this? | PubMed ID: 17599626 | Fulltext

Effect of vitamin K2 on the recurrence in patients with hepatocellular carcinoma.

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Hotta N, Ayada M, Sato K, Ishikawa T, Okumura A, Matsumoto E, Ohashi T, and Kakumu S

Hepato-gastroenterology 54(79):2073-7, 2007 - Who cited this? | PubMed ID: 18251162 | Fulltext

[Strategy for acid suppressant-resistant NERD].

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Konagaya T, Kaneko H, Funaki Y, and Kakumu S

Nippon Shokakibyo Gakkai zasshi The Japanese journal of gastro-enterology 103(11):1223-32, 2006 Nov - Who cited this? | PubMed ID: 17085902 | Fulltext

[Pathophysiology of functional dyspepsia].

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Kaneko H, Konagaya T, Iida A, and Kakumu S

Nippon Shokakibyo Gakkai zasshi The Japanese journal of gastro-enterology 103(9):1031-8, 2006 Sep - Who cited this? | PubMed ID: 16953099 | Fulltext

Influence of genotypes and precore mutations on fulminant or chronic outcome of acute hepatitis B virus infection.

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Ozasa A, Tanaka Y, Orito E, Sugiyama M, Kang JH, Hige S, Kuramitsu T, Suzuki K, Tanaka E, Okada S, Tokita H, Asahina Y, Inoue K, Kakumu S, Okanoue T, Murawaki Y,

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Hepatology (Baltimore, Md.) 44(2):326-34, 2006 Aug - Who cited this? | PubMed ID: 16871568 | Fulltext

Alteration of serum cytokine balances among different phases of chronic hepatitis B virus infection.

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Ayada M, Ishikawa T, Okumura A, Tanabe J, Ito H, Ohashi T, Matsumoto E, Sato K, Hotta N, Fukuzawa Y, and Kakumu S

Hepatology research : the official journal of the Japan Society of Hepatology 34(4):214-21, 2006 Apr - Who cited this? | PubMed ID: 16469532 | Fulltext

Lethal endotoxic shock using alpha-galactosylceramide sensitization as a new experimental model of septic shock.

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Ito H, Koide N, Hassan F, Islam S, Tumurkhuu G, Mori I, Yoshida T, Kakumu S, Moriwaki H, and Yokochi T

Laboratory investigation; a journal of technical methods and pathology 86(3):254-61, 2006 Mar - Who cited this? | PubMed ID: 16446706 | Fulltext

Plasma amino acid profiles applied for diagnosis of advanced liver fibrosis in patients with chronic hepatitis C infection.

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Zhang Q, Takahashi M, Noguchi Y, Sugimoto T, Kimura T, Okumura A, Ishikawa T, and Kakumu S

Hepatology research : the official journal of the Japan Society of Hepatology 34(3):170-7, 2006 Mar - Who cited this? | PubMed ID: 16436332 | Fulltext

The SHAP-hyaluronan complex in serum from patients with chronic liver diseases caused by hepatitis virus infection.

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Shen L, Zhuo L, Okumura A, Ishikawa T, Miyachi M, Owa Y, Ishizawa T, Sugiura N, Nagata Y, Nonami T, Kakumu S, and Kimata K

Hepatology research : the official journal of the Japan Society of Hepatology 34(3):178-86, 2006 Mar - Who cited this? | PubMed ID: 16448842 | Fulltext

Successful treatment of severe pouchitis with rebamipide refractory to antibiotics and corticosteroids: a case report.

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Miyata M, Konagaya T, Kakumu S, and Mori T

World journal of gastroenterology : WJG 12(4):656, 2006 Jan 28 - Who cited this? | PubMed ID: 16489687 | Fulltext

Four-dimensional ultrasonography for therapeutic radiofrequency ablation for hepatocellular carcinoma.

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Hotta N, Maeno T, Ayada M, Sato K, Ishikawa T, Okumura A, Matsumoto E, Fukuzawa Y, and Kakumu S

Hepato-gastroenterology 53(70):521-5, 2006 - Who cited this? | PubMed ID: 16995453 | Fulltext

Timing of interferon therapy and sources of infection in patients with acute hepatitis C.

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Ogata K, Ide T, Kumashiro R, Kumada H, Yotsuyanagi H, Okita K, Akahane Y, Kaneko S, Tsubouchi H, Tanaka E, Moriwaki H, Nishiguchi S, Kakumu S, Mizokami M, Iino S, and Sata M

Hepatology research : the official journal of the Japan Society of Hepatology 34(1):35-40, 2006 Jan - Who cited this? | PubMed ID: 16359917 | Fulltext

Rebamipide enemas-new effective treatment for patients with corticosteroid dependent or resistant ulcerative colitis.

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Miyata M, Kasugai K, Ishikawa T, Kakumu S, Onishi M, and Mori T

Digestive diseases and sciences 50 Suppl 1:S119-23, 2005 Oct - Who cited this? | PubMed ID: 16184413 | Fulltext

Changes in natural killer T cells subsets during therapy in type C hepatitis and hepatocellular carcinoma.

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Okumura A, Ishikawa T, Maeno T, Sato K, Ayada M, Hotta N, Yamauchi T, Fukuzawa Y, and Kakumu S

Hepatology research : the official journal of the Japan Society of Hepatology 32(4):213-7, 2005 Aug - Who cited this? | PubMed ID: 15905121 | Fulltext

Continued ribavirin monotherapy following interferon-ribavirin combination therapy is not effective for chronic hepatitis C.

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Kakumu S

Hepatology research : the official journal of the Japan Society of Hepatology 32(2):77-8, 2005 Jun - Who cited this? | PubMed ID: 15857808 | Fulltext

The efficacy and safety of thymosin alpha-1 in Japanese patients with chronic hepatitis B; results from a randomized clinical trial.

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Iino S, Toyota J, Kumada H, Kiyosawa K, Kakumu S, Sata M, Suzuki H, and Martins EB

Journal of viral hepatitis 12(3):300-6, 2005 May - Who cited this? | PubMed ID: 15850471 | Fulltext

Impact of daily high-dose IFNalpha-2b plus ribavirin combination therapy on reduction of ALT levels in patients with chronic hepatitis C with genotype 1 and high HCV RNA levels.

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Iino S, Tomita E, Kumada H, Suzuki H, Toyota J, Kiyosawa K, Tanikawa K, Sata M, Hayashi N, Kakumu S, Matsushima T, and Mizokami M

Hepatology research : the official journal of the Japan Society of Hepatology 31(2):88-94, 2005 Feb - Who cited this? | PubMed ID: 15777649 | Fulltext

Differential diagnosis of pancreatic cancer and focal pancreatitis by using EUS-guided FNA.

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Takahashi K, Yamao K, Okubo K, Sawaki A, Mizuno N, Ashida R, Koshikawa T, Ueyama Y, Kasugai K, Hase S, and Kakumu S

Gastrointestinal endoscopy 61(1):76-9, 2005 Jan - Who cited this? | PubMed ID: 15672060 | Fulltext

Advanced dynamic flow imaging with contrast-enhanced ultrasonography for the evaluation of tumor vascularity in liver tumors.

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Hotta N, Tagaya T, Maeno T, Ayada M, Sato K, Ishikawa T, Okumura A, Fukuzawa Y, and Kakumu S

Clinical imaging 29(1):34-41, 2005 - Who cited this? | PubMed ID: 15859016 | Fulltext

A case of hepatocellular carcinoma (HCC) treated with radiofrequency ablation (RFA) using 4D real-time ultrasound system.

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Hotta N, Fukuzawa Y, Ayada M, Sato K, Maeno T, Tagaya T, Okumura A, Ishikawa T, Ito Y, and Kakumu S

Hepato-gastroenterology 52(64):1224-7, 2005 - Who cited this? | PubMed ID: 16001667 | Fulltext

Augmentation of lipopolysaccharide-induced nitric oxide production by alpha-galactosylceramide in mouse peritoneal cells.

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Ito H, Koide N, Morikawa A, Hassan F, Islam S, Tumurkhuu G, Mori I, Yoshida T, Kakumu S, Moriwaki H, and Yokochi T

Journal of endotoxin research 11(4):213-9, 2005 - Who cited this? | PubMed ID: 16176657 | Fulltext

Interferon therapy for aged patients with chronic hepatitis C: improved survival in patients exhibiting a biochemical response.

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Imai Y, Kasahara A, Tanaka H, Okanoue T, Hiramatsu N, Tsubouchi H, Yoshioka K, Kawata S, Tanaka E, Hino K, Hayashi K, Tamura S, Itoh Y, Sasaki Y, Kiyosawa K, Kakumu S,

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Journal of gastroenterology 39(11):1069-77, 2004 Nov - Who cited this? | PubMed ID: 15580400 | Fulltext

Is mortality from liver disease associated with normal serum aminotransferase concentrations?.

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Kakumu S

Nature clinical practice. Gastroenterology & hepatology 1(1):22-3, 2004 Nov - Who cited this? | PubMed ID: 16265039 | Fulltext

Characteristics of patients with chronic hepatitis C who develop hepatocellular carcinoma after a sustained response to interferon therapy.

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Makiyama A, Itoh Y, Kasahara A, Imai Y, Kawata S, Yoshioka K, Tsubouchi H, Kiyosawa K, Kakumu S, Okita K, Hayashi N, and Okanoue T

Cancer 101(7):1616-22, 2004 Oct 1 - Who cited this? | PubMed ID: 15378504 | Fulltext

[Interferon therapy for chronic hepatitis B].

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Kakumu S

Nippon rinsho. Japanese journal of clinical medicine 62 Suppl 8:315-20, 2004 Aug - Who cited this? | PubMed ID: 15453337 | Fulltext

[Combination therapy of lamivudine and HB vaccine for the treatment of chronic hepatitis B].

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Ishikawa T and Kakumu S

Nippon rinsho. Japanese journal of clinical medicine 62 Suppl 8:331-5, 2004 Aug - Who cited this? | PubMed ID: 15453340 | Fulltext

[Relationship between the dynamics of cytokines and the phenotypes of the disease in chronic HCV infection].

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Okumura A and Kakumu S

Nippon rinsho. Japanese journal of clinical medicine 62 Suppl 7(Pt 1):164-9, 2004 Jul - Who cited this? | PubMed ID: 15359786 | Fulltext

[Clinical significance of measuring HCV-RNA levels in patients with chronic hepatitis C by IFN treatment, including combination therapy with ribavirin].

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Kakumu S

Nippon rinsho. Japanese journal of clinical medicine 62 Suppl 7(Pt 1):507-10, 2004 Jul - Who cited this? | PubMed ID: 15359851 | Fulltext

[Selection of therapy in patients with chronic hepatitis C showing features like autoimmune hepatitis].

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Kakumu S

Nippon rinsho. Japanese journal of clinical medicine 62 Suppl 7(Pt 1):663-6, 2004 Jul - Who cited this? | PubMed ID: 15359881 | Fulltext

A significant reduction in serum alanine aminotransferase levels after 3-month iron reduction therapy for chronic hepatitis C: a multicenter, prospective, randomized, controlled trial in Japan.

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Yano M, Hayashi H, Yoshioka K, Kohgo Y, Saito H, Niitsu Y, Kato J, Iino S, Yotsuyanagi H, Kobayashi Y, Kawamura K, Kakumu S, Kaito M, Ikoma J, Wakusawa S, Okanoue T,

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Journal of gastroenterology 39(6):570-4, 2004 Jun - Who cited this? | PubMed ID: 15235875 | Fulltext

Interferon treatment improves survival in chronic hepatitis C patients showing biochemical as well as virological responses by preventing liver-related death.

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Kasahara A, Tanaka H, Okanoue T, Imai Y, Tsubouchi H, Yoshioka K, Kawata S, Tanaka E, Hino K, Hayashi K, Tamura S, Itoh Y, Kiyosawa K, Kakumu S, Okita K, and Hayashi N

Journal of viral hepatitis 11(2):148-56, 2004 Mar - Who cited this? | PubMed ID: 14996350 | Fulltext

Mechanisms of increased insulin resistance in non-cirrhotic patients with chronic hepatitis C virus infection.

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Maeno T, Okumura A, Ishikawa T, Kato K, Sakakibara F, Sato K, Ayada M, Hotta N, Tagaya T, Fukuzawa Y, and Kakumu S

Journal of gastroenterology and hepatology 18(12):1358-63, 2003 Dec - Who cited this? | PubMed ID: 14675263 | Fulltext

Enhanced somatostatin secretion into the gastric juice with recovery of basal acid output after Helicobacter pylori eradication in gastric ulcers.

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Hayakawa T, Kaneko H, Konagaya T, Shinozaki K, Kasahara A, Funaki Y, Mori S, Yokoi T, Hirooka Y, Kusugami K, and Kakumu S

Journal of gastroenterology and hepatology 18(5):505-11, 2003 May - Who cited this? | PubMed ID: 12702041 | Fulltext

Epidemiologic and virologic characteristics of hepatitis B virus genotype B having the recombination with genotype C.

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Sugauchi F, Orito E, Ichida T, Kato H, Sakugawa H, Kakumu S, Ishida T, Chutaputti A, Lai CL, Gish RG, Ueda R, Miyakawa Y, and Mizokami M

Gastroenterology 124(4):925-32, 2003 Apr - Who cited this? | PubMed ID: 12671889 | Fulltext

Lack of tumor necrosis factor alpha induces impaired proliferation of hepatitis B virus-specific cytotoxic T lymphocytes.

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Kasahara S, Ando K, Saito K, Sekikawa K, Ito H, Ishikawa T, Ohnishi H, Seishima M, Kakumu S, and Moriwaki H

Journal of virology 77(4):2469-76, 2003 Feb - Who cited this? | PubMed ID: 12551985 | Fulltext

Usefulness of contrast-enhanced ultrasonography with dynamic flow imaging to evaluate therapeutic effects for hepatocellular carcinoma.

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Hotta N, Tagaya T, Maeno T, Ishikawa T, Okumura A, Fukuzawa Y, and Kakumu S

Hepato-gastroenterology 50(54):1867-71, 2003 - Who cited this? | PubMed ID: 14696421 | Fulltext

Prevalence of diabetes mellitus in Japanese patients infected chronically with hepatitis C virus.

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Arao M, Murase K, Kusakabe A, Yoshioka K, Fukuzawa Y, Ishikawa T, Tagaya T, Yamanouchi K, Ichimiya H, Sameshima Y, and Kakumu S

Journal of gastroenterology 38(4):355-60, 2003 - Who cited this? | PubMed ID: 12743775 | Fulltext

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