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Papers authored by Ikuta M

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Reduced red blood cell velocity in nail-fold capillaries as a sensitive and specific indicator of microcirculation injury in systemic sclerosis.

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Mugii N, Hasegawa M, Hamaguchi Y, Tanaka C, Kaji K, Komura K, Ueda-Hayakawa I, Horie S, Ikuta M, Tachino K, Ogawa F, Sato S, Fujimoto M, and Takehara K

Rheumatology (Oxford, England) 48(6):696-703, 2009 Jun - Who cited this? | PubMed ID: 19439504 | Fulltext

Synthesis and Pharmacological Evaluation of New 1-Hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines as Norepinephrine Potentiators.

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Ikeuchi M, Ikuta M, Hariki M, Ikeuchi M, Maruyama S, Nakase M, Sakamoto K, Yoshioka Y, Yamauchi A, and Kihara M

Chemical & pharmaceutical bulletin 57(5):443-5, 2009 May - Who cited this? | PubMed ID: 19420772 | Fulltext

Crystal structures of the N-terminal kinase domain of human RSK1 bound to three different ligands: Implications for the design of RSK1 specific inhibitors.

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Ikuta M, Kornienko M, Byrne N, Reid JC, Mizuarai S, Kotani H, and Munshi SK

Protein science : a publication of the Protein Society 16(12):2626-35, 2007 Dec - Who cited this? | PubMed ID: 17965187 | Fulltext

Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinase.

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Garbaccio RM, Huang S, Tasber ES, Fraley ME, Yan Y, Munshi S, Ikuta M, Kuo L, Kreatsoulas C, Stirdivant S, Drakas B, Rickert K, Walsh ES, Hamilton KA, Buser CA, Hardwick J,

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Bioorganic & medicinal chemistry letters 17(22):6280-5, 2007 Nov 15 - Who cited this? | PubMed ID: 17900896 | Fulltext

Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors.

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Brnardic EJ, Garbaccio RM, Fraley ME, Tasber ES, Steen JT, Arrington KL, Dudkin VY, Hartman GD, Stirdivant SM, Drakas BA, Rickert K, Walsh ES, Hamilton K, Buser CA, Hardwick J, Tao W,

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Bioorganic & medicinal chemistry letters 17(21):5989-94, 2007 Nov 1 - Who cited this? | PubMed ID: 17804227 | Fulltext

3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6.

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Fraley ME, Steen JT, Brnardic EJ, Arrington KL, Spencer KL, Hanney BA, Kim Y, Hartman GD, Stirdivant SM, Drakas BA, Rickert K, Walsh ES, Hamilton K, Buser CA, Hardwick J, Tao W,

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Bioorganic & medicinal chemistry letters 16(23):6049-53, 2006 Dec 1 - Who cited this? | PubMed ID: 16978863 | Fulltext

Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors.

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Huang S, Garbaccio RM, Fraley ME, Steen J, Kreatsoulas C, Hartman G, Stirdivant S, Drakas B, Rickert K, Walsh E, Hamilton K, Buser CA, Hardwick J, Mao X, Abrams M, Beck S,

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Bioorganic & medicinal chemistry letters 16(22):5907-12, 2006 Nov 15 - Who cited this? | PubMed ID: 16990002 | Fulltext

Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure.

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Kawanishi N, Sugimoto T, Shibata J, Nakamura K, Masutani K, Ikuta M, and Hirai H

Bioorganic & medicinal chemistry letters 16(19):5122-6, 2006 Oct 1 - Who cited this? | PubMed ID: 16876403 | Fulltext

The efficacy of self-administered stretching for finger joint motion in Japanese patients with systemic sclerosis.

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Mugii N, Hasegawa M, Matsushita T, Kondo M, Orito H, Yanaba K, Komura K, Hayakawa I, Hamaguchi Y, Ikuta M, Tachino K, Fujimoto M, Takehara K, and Sato S

The Journal of rheumatology 33(8):1586-92, 2006 Aug - Who cited this? | PubMed ID: 16881115 | Fulltext

Promotor hypermethylation of p14ARF is a key alteration for progression of oral squamous cell carcinoma.

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Ishida E, Nakamura M, Ikuta M, Shimada K, Matsuyoshi S, Kirita T, and Konishi N

Oral oncology 41(6):614-22, 2005 Jul - Who cited this? | PubMed ID: 15975525 | Fulltext

Genetic and epigenetic alteration profiles for multiple genes in salivary gland carcinomas.

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Kishi M, Nakamura M, Nishimine M, Ikuta M, Kirita T, and Konishi N

Oral oncology 41(2):161-9, 2005 Feb - Who cited this? | PubMed ID: 15695118 | Fulltext

Syntheses of hexakis(4-functionalized-phenyl)benzenes and hexakis[4-(4'-functionalized- phenylethynyl)phenyl]benzenes directed to host molecules for guest-inclusion networks.

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Kobayashi K, Kobayashi N, Ikuta M, Therrien B, Sakamoto S, and Yamaguchi K

The Journal of organic chemistry 70(2):749-52, 2005 Jan 21 - Who cited this? | PubMed ID: 15651837 | Fulltext

Hypoxia-induced activation of the retinoic acid receptor-related orphan receptor alpha4 gene by an interaction between hypoxia-inducible factor-1 and Sp1.

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Miki N, Ikuta M, and Matsui T

The Journal of biological chemistry 279(15):15025-31, 2004 Apr 9 - Who cited this? | PubMed ID: 14742449 | Fulltext

Heparanase and tumor invasion patterns in human oral squamous cell carcinoma xenografts.

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Kurokawa H, Katsube K, Podyma KA, Ikuta M, Iseki H, Nakajima M, Akashi T, Omura K, Takagi M, and Yanagishita M

Cancer science 94(3):277-85, 2003 Mar - Who cited this? | PubMed ID: 12824922 | Fulltext

Characterization of heparanase from a rat parathyroid cell line.

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Podyma-Inoue KA, Yokote H, Sakaguchi K, Ikuta M, and Yanagishita M

The Journal of biological chemistry 277(36):32459-65, 2002 Sep 6 - Who cited this? | PubMed ID: 12077130 | Fulltext

Design and synthesis of novel tetra-peptide motilin agonists.

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Haramura M, Tsuzuki K, Okamachi A, Yogo K, Ikuta M, Kozono T, Takanashi H, and Murayama E

Bioorganic & medicinal chemistry 10(6):1805-11, 2002 Jun - Who cited this? | PubMed ID: 11937338 | Fulltext

Full-color imaging through a turbid medium by use of photorefractive coherence gating and a technique to separate the recording spaces.

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Ikuta M, Hagari R, Obara M, Tokida Y, Oda M, and Shiratori A

Applied optics 41(10):1882-7, 2002 Apr 1 - Who cited this? | PubMed ID: 11936785 | Fulltext

Syntheses and characterizations of 4-(3,17beta-dihydroxyestra-1,3,5(10)-trien-6alpha- and 6beta-yl)amino-7-nitro-2,1,3-benzoxadiazoles as fluorescent probes.

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Oe T, Ikuta M, and Toyo'oka T

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 18(2):161-5, 2002 Feb - Who cited this? | PubMed ID: 11874119 | Fulltext

Design and synthesis of motilin antagonists derived from the [1-4] fragment of porcine motilin.

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Haramura M, Okamachi A, Tsuzuki K, Yogo K, Ikuta M, Kozono T, Takanashi H, and Murayama E

Journal of medicinal chemistry 45(3):670-5, 2002 Jan 31 - Who cited this? | PubMed ID: 11806718 | Fulltext

Structure-based generation of a new class of potent Cdk4 inhibitors: new de novo design strategy and library design.

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Honma T, Hayashi K, Aoyama T, Hashimoto N, Machida T, Fukasawa K, Iwama T, Ikeura C, Ikuta M, Suzuki-Takahashi I, Iwasawa Y, Hayama T, Nishimura S, and Morishima H

Journal of medicinal chemistry 44(26):4615-27, 2001 Dec 20 - Who cited this? | PubMed ID: 11741479 | Fulltext

A novel approach for the development of selective Cdk4 inhibitors: library design based on locations of Cdk4 specific amino acid residues.

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Honma T, Yoshizumi T, Hashimoto N, Hayashi K, Kawanishi N, Fukasawa K, Takaki T, Ikeura C, Ikuta M, Suzuki-Takahashi I, Hayama T, Nishimura S, and Morishima H

Journal of medicinal chemistry 44(26):4628-40, 2001 Dec 20 - Who cited this? | PubMed ID: 11741480 | Fulltext

Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA.

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Tanaka Y, Nureki O, Kurumizaka H, Fukai S, Kawaguchi S, Ikuta M, Iwahara J, Okazaki T, and Yokoyama S

The EMBO journal 20(23):6612-8, 2001 Dec 3 - Who cited this? | PubMed ID: 11726497 | Fulltext

Two new steroidal derivatives from the fruit body of Chlorophyllum molybdites.

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Yoshikawa K, Ikuta M, Arihara S, Matsumura E, and Katayama S

Chemical & pharmaceutical bulletin 49(8):1030-2, 2001 Aug - Who cited this? | PubMed ID: 11515573 | Fulltext

Crystallographic approach to identification of cyclin-dependent kinase 4 (CDK4)-specific inhibitors by using CDK4 mimic CDK2 protein.

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Ikuta M, Kamata K, Fukasawa K, Honma T, Machida T, Hirai H, Suzuki-Takahashi I, Hayama T, and Nishimura S

The Journal of biological chemistry 276(29):27548-54, 2001 Jul 20 - Who cited this? | PubMed ID: 11335721 | Fulltext

Expression of heparanase in oral cancer cell lines and oral cancer tissues.

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Ikuta M, Podyma KA, Maruyama K, Enomoto S, and Yanagishita M

Oral oncology 37(2):177-84, 2001 Feb - Who cited this? | PubMed ID: 11167146 | Fulltext

Design and synthesis of N-terminal cyclic motilin partial peptides: a novel pure motilin antagonist.

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Haramura M, Okamachi A, Tsuzuki K, Yogo K, Ikuta M, Kozono T, Takanashi H, and Murayama E

Chemical & pharmaceutical bulletin 49(1):40-3, 2001 Jan - Who cited this? | PubMed ID: 11201222 | Fulltext

Structure-activity study of intact porcine motilin.

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Haramura M, Tsuzuki K, Okamachi A, Yogo K, Ikuta M, Kozono T, Takanashi H, and Murayama E

Chemical & pharmaceutical bulletin 47(11):1555-9, 1999 Nov - Who cited this? | PubMed ID: 10605054 | Fulltext

Insulin and glucagon secretion in goats (Capra hircus Linnaeus) exposed to cold.

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Oda S, Ikuta M, Kuhara T, Ohneda A, and Sasaki Y

Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 111(2):303-7, 1995 Jun - Who cited this? | PubMed ID: 8521249 | Fulltext

GM-109: a novel, selective motilin receptor antagonist in the smooth muscle of the rabbit small intestine.

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Takanashi H, Yogo K, Ozaki K, Ikuta M, Akima M, Koga H, and Nabata H

The Journal of pharmacology and experimental therapeutics 273(2):624-8, 1995 May - Who cited this? | PubMed ID: 7752063 | Fulltext

Determination of amino acids in human plasma by liquid chromatography with postcolumn ninhydrin derivatization using a hydroxyapatite cartridge for precolumn deproteination.

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Iwase H, Ozawa S, Ikuta M, and Ono I

Journal of chromatography. B, Biomedical applications 663(1):15-24, 1995 Jan 6 - Who cited this? | PubMed ID: 7704203 | Fulltext

Renal handling of phosphate can predict height velocity during growth hormone therapy for short children.

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Nishiyama S, Ikuta M, Nakamura T, Tomoeda S, and Matsuda I

The Journal of clinical endocrinology and metabolism 74(4):906-9, 1992 Apr - Who cited this? | PubMed ID: 1548358 | Fulltext

Interleukin 6 inhibits delayed-type hypersensitivity and the development of adjuvant arthritis.

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Mihara M, Ikuta M, Koishihara Y, and Ohsugi Y

European journal of immunology 21(10):2327-31, 1991 Oct - Who cited this? | PubMed ID: 1915548 | Fulltext

UMC, another Cromer-related blood group antigen.

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Daniels GL, Okubo Y, Yamaguchi H, Seno T, and Ikuta M

Transfusion 29(9):794-7, 1989 - Who cited this? | PubMed ID: 2480010 | Fulltext

Effect of serum magnesium concentration on renal handling of phosphate in a patient with primary hypomagnesemia.

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Nishiyama S, Mitsubuchi H, Ikuta M, Ohta T, and Matsuda I

Endocrinologia japonica 35(1):159-64, 1988 Feb - Who cited this? | PubMed ID: 3396512 | Fulltext

Alpha-2-HS-glycoprotein (A2HS) polymorphism in a Japanese population: existence of two new variants.

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Umetsu K, Yuasa I, Ikuta M, and Suzuki T

Jinrui idengaku zasshi. The Japanese journal of human genetics 32(3):263-6, 1987 Sep - Who cited this? | PubMed ID: 3448309 | Fulltext

Long-dormant invasive mole associated with multiple malignancies.

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Sato H, Matsuda M, Ikuta M, Hada Y, Kusumoto G, and Kirimoto K

Gynecologic oncology 22(2):240-3, 1985 Oct - Who cited this? | PubMed ID: 2996995 | Fulltext

[Nursing of a schizophrenic patient with accentuated stereotyped behaviors and a difficulty in participating in group activities].

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Matsuo M and Ikuta M

Kurinikaru sutadi = Clinical study 6(10):1210-5, 1985 Oct - Who cited this? | PubMed ID: 3853693 | Fulltext

[Antihypertensive effect of nasal nifedipine and its plasma concentration during anesthesia and surgery].

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Yamaoka H, Komatsu T, Tomemori N, Fujise K, Hayama K, Ikuta M, and Izutani R

Masui. The Japanese journal of anesthesiology 34(5):632-6, 1985 May - Who cited this? | PubMed ID: 4032692 | Fulltext

Q value in bacterial hemagglutination.

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Hashimoto M, Horiuchi S, Misawa H, Ikuta M, and Suzuki S

The Bulletin of Tokyo Medical and Dental University 18(4):247-68, 1971 Dec - Who cited this? | PubMed ID: 4948563 | Fulltext

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