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Papers authored by Ikeno Y

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Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.

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Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, and Van Remmen H

The journals of gerontology. Series A, Biological sciences and medical sciences 64(12):1212-20, 2009 Dec - Who cited this? | PubMed ID: 19776219 | Fulltext

Overexpression of mn superoxide dismutase does not increase life span in mice.

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Jang YC, Pérez VI, Song W, Lustgarten MS, Salmon AB, Mele J, Qi W, Liu Y, Liang H, Chaudhuri A, Ikeno Y, Epstein CJ, Van Remmen H, and Richardson A

The journals of gerontology. Series A, Biological sciences and medical sciences 64(11):1114-25, 2009 Nov - Who cited this? | PubMed ID: 19633237 | Fulltext

Efficiency of cell-penetrating peptides on the nasal and intestinal absorption of therapeutic peptides and proteins.

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Khafagy el-S, Morishita M, Kamei N, Eda Y, Ikeno Y, and Takayama K

International journal of pharmaceutics 381(1):49-55, 2009 Oct 20 - Who cited this? | PubMed ID: 19646515 | Fulltext

Is the oxidative stress theory of aging dead?.

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Pérez VI, Bokov A, Remmen HV, Mele J, Ran Q, Ikeno Y, and Richardson A

Biochimica et biophysica acta 1790(10):1005-14, 2009 Oct - Who cited this? | PubMed ID: 19524016 | Fulltext

Lifespan extension in genetically modified mice.

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Ladiges W, Van Remmen H, Strong R, Ikeno Y, Treuting P, Rabinovitch P, and Richardson A

Aging cell 8(4):346-52, 2009 Aug - Who cited this? | PubMed ID: 19485964 | Fulltext

Reduced incidence and delayed occurrence of fatal neoplastic diseases in growth hormone receptor/binding protein knockout mice.

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Ikeno Y, Hubbard GB, Lee S, Cortez LA, Lew CM, Webb CR, Berryman DE, List EO, Kopchick JJ, and Bartke A

The journals of gerontology. Series A, Biological sciences and medical sciences 64(5):522-9, 2009 May - Who cited this? | PubMed ID: 19228785 | Fulltext

Lysophosphatidylcholine protects cerebellar granule neurons from apoptotic cell death.

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Ikeno Y, Cheon SH, Konno N, Nakamura A, Kitamoto K, and Arioka M

Journal of neuroscience research 87(1):190-9, 2009 Jan - Who cited this? | PubMed ID: 18711725 | Fulltext

Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span.

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Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK, Perez E, Jamieson HA, Zhang Y, Dunn SR, Sharma K, Pleshko N, Woollett LA,

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Cell metabolism, 2008 Jul 2 - Who cited this? | PubMed ID: 18599363 | Fulltext

Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress.

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Pérez VI, Lew CM, Cortez LA, Webb CR, Rodriguez M, Liu Y, Qi W, Li Y, Chaudhuri A, Van Remmen H, Richardson A, and Ikeno Y

Free radical biology & medicine 44(5):882-92, 2008 Mar 1 - Who cited this? | PubMed ID: 18164269 | Fulltext

Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells.

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Kagawa T, Watanabe N, Mochizuki K, Numari A, Ikeno Y, Itoh J, Tanaka H, Arias IM, and Mine T

American journal of physiology. Gastrointestinal and liver physiology 294(1):G58-67, 2008 Jan - Who cited this? | PubMed ID: 17947449 | Fulltext

Novel neurotrophic effects of sphingosylphosphorylcholine in cerebellar granule neurons and in PC12 cells.

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Konno N, Nakamura A, Ikeno Y, Cheon SH, Kitamoto K, and Arioka M

Biochemical and biophysical research communications 364(1):163-8, 2007 Dec 7 - Who cited this? | PubMed ID: 17935698 | Fulltext

Plasma glucose and the action of calorie restriction on aging.

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McCarter R, Mejia W, Ikeno Y, Monnier V, Kewitt K, Gibbs M, McMahan A, and Strong R

The journals of gerontology. Series A, Biological sciences and medical sciences 62(10):1059-70, 2007 Oct - Who cited this? | PubMed ID: 17921417 | Fulltext

Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis.

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Ran Q, Liang H, Ikeno Y, Qi W, Prolla TA, Roberts LJ, Wolf N, VanRemmen H, and Richardson A

The journals of gerontology. Series A, Biological sciences and medical sciences 62(9):932-42, 2007 Sep - Who cited this? | PubMed ID: 17895430 | Fulltext

Caspase-2 deficiency enhances aging-related traits in mice.

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Zhang Y, Padalecki SS, Chaudhuri AR, De Waal E, Goins BA, Grubbs B, Ikeno Y, Richardson A, Mundy GR, and Herman B

Mechanisms of ageing and development 128(2):213-21, 2007 Feb - Who cited this? | PubMed ID: 17188333 | Fulltext

Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate.

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Cabelof DC, Ikeno Y, Nyska A, Busuttil RA, Anyangwe N, Vijg J, Matherly LH, Tucker JD, Wilson SH, Richardson A, and Heydari AR

Cancer research 66(15):7460, 2006 Aug 1 - Who cited this? | PubMed ID: 16885342 | Fulltext

Do long-lived mutant and calorie-restricted mice share common anti-aging mechanisms?-a pathological point of view.

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Ikeno Y, Lew CM, Cortez LA, Webb CR, Lee S, and Hubbard GB

Age (Dordrecht, Netherlands) 28(2):163-71, 2006 Jun - Who cited this? | PubMed ID: 19943137 | Fulltext

Housing density does not influence the longevity effect of calorie restriction.

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Ikeno Y, Hubbard GB, Lee S, Richardson A, Strong R, Diaz V, and Nelson JF

The journals of gerontology. Series A, Biological sciences and medical sciences 60(12):1510-7, 2005 Dec - Who cited this? | PubMed ID: 16424282 | Fulltext

Secretory phospholipases A2 induce neurite outgrowth in PC12 cells through lysophosphatidylcholine generation and activation of G2A receptor.

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Ikeno Y, Konno N, Cheon SH, Bolchi A, Ottonello S, Kitamoto K, and Arioka M

The Journal of biological chemistry 280(30):28044-52, 2005 Jul 29 - Who cited this? | PubMed ID: 15927955 | Fulltext

Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span.

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Sonntag WE, Carter CS, Ikeno Y, Ekenstedt K, Carlson CS, Loeser RF, Chakrabarty S, Lee S, Bennett C, Ingram R, Moore T, and Ramsey M

Endocrinology 146(7):2920-32, 2005 Jul - Who cited this? | PubMed ID: 15790724 | Fulltext

A novel neurotrophic role of secretory phospholipases A2 for cerebellar granule neurons.

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Arioka M, Cheon SH, Ikeno Y, Nakashima S, and Kitamoto K

FEBS letters 579(12):2693-701, 2005 May 9 - Who cited this? | PubMed ID: 15862311 | Fulltext

MRG15 regulates embryonic development and cell proliferation.

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Tominaga K, Kirtane B, Jackson JG, Ikeno Y, Ikeda T, Hawks C, Smith JR, Matzuk MM, and Pereira-Smith OM

Molecular and cellular biology 25(8):2924-37, 2005 Apr - Who cited this? | PubMed ID: 15798182 | Fulltext

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging.

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Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, and Richardson A

Physiological genomics 16(1):29-37, 2003 Dec 16 - Who cited this? | PubMed ID: 14679299 | Fulltext

Secretory phospholipases A2 induce neurite outgrowth in PC12 cells.

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Nakashima S, Ikeno Y, Yokoyama T, Kuwana M, Bolchi A, Ottonello S, Kitamoto K, and Arioka M

The Biochemical journal 376(Pt 3):655-66, 2003 Dec 15 - Who cited this? | PubMed ID: 12967323 | Fulltext

Delayed occurrence of fatal neoplastic diseases in ames dwarf mice: correlation to extended longevity.

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Ikeno Y, Bronson RT, Hubbard GB, Lee S, and Bartke A

The journals of gerontology. Series A, Biological sciences and medical sciences 58(4):291-6, 2003 Apr - Who cited this? | PubMed ID: 12663691 | Fulltext

Senescent terminal weight loss in the male F344 rat.

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Black BJ, McMahan CA, Masoro EJ, Ikeno Y, and Katz MS

American journal of physiology. Regulatory, integrative and comparative physiology 284(2):R336-42, 2003 Feb - Who cited this? | PubMed ID: 12388451 | Fulltext

Minimal effects of dietary restriction on neuroendocrine carcinogenesis in Rb+/- mice.

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Sharp ZD, Lee WH, Nikitin AY, Flesken-Nikitin A, Ikeno Y, Reddick R, Richardson AG, and Nelson JF

Carcinogenesis 24(2):179-83, 2003 Feb - Who cited this? | PubMed ID: 12584165 | Fulltext

The influence of long-term Aloe vera ingestion on age-related disease in male Fischer 344 rats.

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Ikeno Y, Hubbard GB, Lee S, Yu BP, and Herlihy JT

Phytotherapy research : PTR 16(8):712-8, 2002 Dec - Who cited this? | PubMed ID: 12458471 | Fulltext

Dietary restriction reduces atherosclerosis and oxidative stress in the aorta of apolipoprotein E-deficient mice.

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Guo Z, Mitchell-Raymundo F, Yang H, Ikeno Y, Nelson J, Diaz V, Richardson A, and Reddick R

Mechanisms of ageing and development 123(8):1121-31, 2002 Apr 30 - Who cited this? | PubMed ID: 12044962 | Fulltext

Age-related changes in redox status of rat serum.

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Kim JW, No JK, Ikeno Y, Yu BP, Choi JS, Yokozawa T, and Chung HY

Archives of gerontology and geriatrics 34(1):9-17, 2002 Feb - Who cited this? | PubMed ID: 14764306 | Fulltext

Spontaneous hepatocellular carcinoma is reduced in transgenic mice overexpressing human O6- methylguanine-DNA methyltransferase.

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Zhou ZQ, Manguino D, Kewitt K, Intano GW, McMahan CA, Herbert DC, Hanes M, Reddick R, Ikeno Y, and Walter CA

Proceedings of the National Academy of Sciences of the United States of America 98(22):12566-71, 2001 Oct 23 - Who cited this? | PubMed ID: 11606727 | Fulltext

Gene expression of cyclooxygenase in the aging heart.

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Kim JW, Baek BS, Kim YK, Herlihy JT, Ikeno Y, Yu BP, and Chung HY

The journals of gerontology. Series A, Biological sciences and medical sciences 56(8):B350-5, 2001 Aug - Who cited this? | PubMed ID: 11487593 | Fulltext

Health span and life span in transgenic mice with modulated DNA repair.

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Walter CA, Zhou ZQ, Manguino D, Ikeno Y, Reddick R, Nelson J, Intano G, Herbert DC, McMahan CA, and Hanes M

Annals of the New York Academy of Sciences 928:132-40, 2001 Apr - Who cited this? | PubMed ID: 11795504 | Fulltext

Effects of aging and caloric restriction on IGF-I, IGF-I receptor, IGFBP-3 and IGFBP-4 gene expression in the rat stomach and colon.

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Hallberg LM, Ikeno Y, Englander E, and Greeley GH

Regulatory peptides 89(1-3):37-44, 2000 May 10 - Who cited this? | PubMed ID: 10771311 | Fulltext

Regional difference of ROS generation, lipid peroxidation, and antioxidant enzyme activity in rat brain and their dietary modulation.

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Baek BS, Kwon HJ, Lee KH, Yoo MA, Kim KW, Ikeno Y, Yu BP, and Chung HY

Archives of pharmacal research 22(4):361-6, 1999 Aug - Who cited this? | PubMed ID: 10489874 | Fulltext

Downregulation of telomerase in rat during the aging process.

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Kang HK, Kim MS, Kim ND, Yoo MA, Kim KW, Kim J, Ikeno Y, Yu BP, and Chung HY

Molecules and cells 9(3):286-91, 1999 Jun 30 - Who cited this? | PubMed ID: 10420988 | Fulltext

Modulation of renal xanthine oxidoreductase in aging: gene expression and reactive oxygen species generation.

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Chung HY, Song SH, Kim HJ, Ikeno Y, and Yu BP

The journal of nutrition, health & aging 3(1):19-23, 1999 - Who cited this? | PubMed ID: 10888479 | Fulltext

Oxidant-mediated repression of mitochondrial transcription in diabetic rats.

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Kristal BS, Koopmans SJ, Jackson CT, Ikeno Y, Park BJ, and Yu BP

Free radical biology & medicine 22(5):813-22, 1997 - Who cited this? | PubMed ID: 9119250 | Fulltext

Physical activity as a factor in the action of dietary restriction on aging: effects in Fischer 344 rats.

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McCarter RJ, Shimokawa I, Ikeno Y, Higami Y, Hubbard GB, Yu BP, and McMahan CA

Aging (Milan, Italy) 9(1-2):73-9, 1997 - Who cited this? | PubMed ID: 9177588 | Fulltext

[An autopsy case of urinary bladder carcinoma with pulmonary infarction and subacute cor pulmonale caused by tumor embolization].

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Suyama N, Mashimoto H, Araki J, Asai S, Ikeno Y, and Ikeda T

Nihon Kyobu Shikkan Gakkai zasshi 32(5):491-6, 1994 May - Who cited this? | PubMed ID: 8084107 | Fulltext

GFAP expression in the subcutaneous tumors of immature glial cell line (HITS glioma) derived from ENU-induced rat glioma.

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Ikeno Y, Shimokawa I, Higami Y, and Ikeda T

Journal of neuro-oncology 17(3):191-204, 1993 Sep - Who cited this? | PubMed ID: 8164056 | Fulltext

[A case of pulmonary asbestosis with slightly increased serum IgE concentration and histopathological changes resembling DIP].

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Ikeno Y, Asai S, Mashimoto H, Shimokawa I, Iwasaki K, Matsuo T, Ikeda T, and Minami H

Nihon Kyobu Shikkan Gakkai zasshi 31(2):219-24, 1993 Feb - Who cited this? | PubMed ID: 8515602 | Fulltext

[A case of interstitial pneumonitis with hemoptysis, BOOP (bronchiolitis obliterans organizing pneumonia) pattern, granulomas and foreign body giant cells in lung biopsy].

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Mashimoto H, Suyama N, Araki J, Asai S, Minami H, and Ikeno Y

Nihon Kyobu Shikkan Gakkai zasshi 30(6):1146-51, 1992 Jun - Who cited this? | PubMed ID: 1507690 | Fulltext

Local formation and degradation of endothelin-1 in guinea pig airway tissues.

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Noguchi K, Fukuroda T, Ikeno Y, Hirose H, Tsukada Y, Nishikibe M, Ikemoto F, Matsuyama K, and Yano M

Biochemical and biophysical research communications 179(2):830-5, 1991 Sep 16 - Who cited this? | PubMed ID: 1898406 | Fulltext

Diffuse infantile fibromatosis.

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Kameda N, Atobe T, Akima M, Fukuoka Y, Ikeno Y, and Saito M

Acta pathologica japonica 28(6):957-62, 1978 Nov - Who cited this? | PubMed ID: 735826 | Fulltext

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