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Papers authored by Ikai A

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Improvement of Determination Technique for Extracting Centerline in Coronary Artery with Calcification on CTA.

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Ikai A, Lee Y, Tsai DY, Yamamoto I, Matsumoto K, and Kimura M

Nippon Hoshasen Gijutsu Gakkai zasshi 65(9):1313-23, 2009 Sep 20 - Who cited this? | PubMed ID: 19828929 | Fulltext

Single molecular dynamic interactions between glycophorin A and lectin as probed by atomic force microscopy.

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Yan C, Yersin A, Afrin R, Sekiguchi H, and Ikai A

Biophysical chemistry 144(1-2):72-7, 2009 Sep - Who cited this? | PubMed ID: 19619933 | Fulltext

High-sensitivity detection of proteins using gel electrophoresis and atomic force microscopy.

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Sekiguchi H, Hidaka A, Shiga Y, Ikai A, and Osada T

Ultramicroscopy 109(8):916-22, 2009 Jul - Who cited this? | PubMed ID: 19345497 | Fulltext

Unfolding study of native bacteriorhodopsin under acidic condition.

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Kodama T, Koyanagi T, Sekiguchi H, Ikai A, and Ohtani H

Ultramicroscopy 109(8):948-51, 2009 Jul - Who cited this? | PubMed ID: 19446397 | Fulltext

Tensile mechanics of alanine-based helical polypeptide: force spectroscopy versus computer simulations.

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Afrin R, Takahashi I, Shiga K, and Ikai A

Biophysical journal 96(3):1105-14, 2009 Feb - Who cited this? | PubMed ID: 19186146 | Fulltext

Detection of mRNA in Single Living Cells Using AFM Nanoprobes.

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Uehara H, Ikai A, and Osada T

Methods in molecular biology (Clifton, N.J.) 544:599-608, 2009 - Who cited this? | PubMed ID: 19488726 | Fulltext

Atomic force microscopy for cellular level manipulation: imaging intracellular structures and DNA delivery through a membrane hole.

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Afrin R, Zohora US, Uehara H, Watanabe-Nakayama T, and Ikai A

Journal of molecular recognition : JMR 22(5):363-72, 2009 - Who cited this? | PubMed ID: 19623603 | Fulltext

Reply to the editor:.

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Ikai A and Sakamoto K

The Journal of thoracic and cardiovascular surgery 136(5):1393-4, 2008 Nov - Who cited this? | PubMed ID: 19026850 | Fulltext

Nanobiomechanics of proteins and biomembrane.

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Ikai A

Philosophical transactions of the Royal Society of London. Series B, Biological sciences 363(1500):2163-71, 2008 Jun 27 - Who cited this? | PubMed ID: 18339603 | Fulltext

Feasibility of the extracardiac conduit Fontan procedure in patients weighing less than 10 kilograms.

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Ikai A, Fujimoto Y, Hirose K, Ota N, Tosaka Y, Nakata T, Ide Y, and Sakamoto K

The Journal of thoracic and cardiovascular surgery 135(5):1145-52, 2008 May - Who cited this? | PubMed ID: 18455596 | Fulltext

Distribution of olfactory marker protein on a tissue section of vomeronasal organ measured by AFM.

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Kim H, Asgari F, Kato-Negishi M, Ohkura S, Okamura H, Arakawa H, Osada T, and Ikai A

Colloids and surfaces. B, Biointerfaces 61(2):311, 2008 Feb 15 - Who cited this? | PubMed ID: 17923395 | Fulltext

Exploring transferrin-receptor interactions at the single-molecule level.

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Yersin A, Osada T, and Ikai A

Biophysical journal 94(1):230-40, 2008 Jan 1 - Who cited this? | PubMed ID: 17872962 | Fulltext

Novel surgical approach 'intrapulmonary-artery septation' for Fontan candidates with unilateral pulmonary arterial hypoplasia or pulmonary venous obstruction.

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Sakamoto K, Ikai A, Fujimoto Y, and Ota N

Interactive cardiovascular and thoracic surgery 6(2):150-4, 2007 Apr - Who cited this? | PubMed ID: 17669796 | Fulltext

Granular tau oligomers as intermediates of tau filaments.

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Maeda S, Sahara N, Saito Y, Murayama M, Yoshiike Y, Kim H, Miyasaka T, Murayama S, Ikai A, and Takashima A

Biochemistry 46(12):3856-61, 2007 Mar 27 - Who cited this? | PubMed ID: 17338548 | Fulltext

Retrospective analysis of stage I Norwood procedures with tricuspid valve insufficiency in the past 5 years.

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Ota N, Ikai A, Hirose K, and Sakamoto K

Interactive cardiovascular and thoracic surgery 6(1):121-3, 2007 Feb - Who cited this? | PubMed ID: 17669787 | Fulltext

mRNA detection of individual cells with the single cell nanoprobe method compared with in situ hybridization.

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Uehara H, Kunitomi Y, Ikai A, and Osada T

Journal of nanobiotechnology 5:7, 2007 - Who cited this? | PubMed ID: 17925043 | Fulltext

Force profiles of protein pulling with or without cytoskeletal links studied by AFM.

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Afrin R and Ikai A

Biochemical and biophysical research communications 348(1):238-44, 2006 Sep 15 - Who cited this? | PubMed ID: 16876121 | Fulltext

Quantification of the number of EP3 receptors on a living CHO cell surface by the AFM.

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Kim H, Arakawa H, Hatae N, Sugimoto Y, Matsumoto O, Osada T, Ichikawa A, and Ikai A

Ultramicroscopy 106(8-9):652 - Who cited this? | PubMed ID: 16677763 | Fulltext

AFM observation of immobilized self-oscillating polymer.

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Ito Y, Hara Y, Uetsuka H, Hasuda H, Onishi H, Arakawa H, Ikai A, and Yoshida R

The journal of physical chemistry. B 110(11):5170-3, 2006 Mar 23 - Who cited this? | PubMed ID: 16539442 | Fulltext

Increased levels of granular tau oligomers: an early sign of brain aging and Alzheimer's disease.

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Maeda S, Sahara N, Saito Y, Murayama S, Ikai A, and Takashima A

Neuroscience research 54(3):197-201, 2006 Mar - Who cited this? | PubMed ID: 16406150 | Fulltext

Local rigidity of a protein molecule.

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Ikai A

Biophysical chemistry 116(3):187-91, 2005 Aug 1 - Who cited this? | PubMed ID: 15882923 | Fulltext

Pretransition and progressive softening of bovine carbonic anhydrase II as probed by single molecule atomic force microscopy.

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Afrin R, Alam MT, and Ikai A

Protein science : a publication of the Protein Society 14(6):1447-57, 2005 Jun - Who cited this? | PubMed ID: 15929995 | Fulltext

Preliminary results of fetal cardiac bypass in nonhuman primates.

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Ikai A, Riemer RK, Ramamoorthy C, Malhotra S, Cassorla L, Amir G, Hanley FL, and Reddy VM

The Journal of thoracic and cardiovascular surgery 129(1):175-81, 2005 Jan - Who cited this? | PubMed ID: 15632840 | Fulltext

Maintenance of pulmonary vasculature tone by blood derived from the inferior vena cava in a rabbit model of cavopulmonary shunt.

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Ikai A, Shirai M, Nishimura K, Ikeda T, Kameyama T, Ueyama K, and Komeda M

The Journal of thoracic and cardiovascular surgery 129(1):199-206, 2005 Jan - Who cited this? | PubMed ID: 15632843 | Fulltext

Origin of mechanical strength of bovine carbonic anhydrase studied by molecular dynamics simulation.

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Ohta S, Alam MT, Arakawa H, and Ikai A

Biophysical journal 87(6):4007-20, 2004 Dec - Who cited this? | PubMed ID: 15377514 | Fulltext

Analysis of force curves obtained on the live cell membrane using chemically modified AFM probes.

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Afrin R, Yamada T, and Ikai A

Ultramicroscopy 100(3-4):187-95, 2004 Aug - Who cited this? | PubMed ID: 15231309 | Fulltext

Quantitative measurement of mRNA at different loci within an individual living cell.

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Uehara H, Osada T, and Ikai A

Ultramicroscopy 100(3-4):197-201, 2004 Aug - Who cited this? | PubMed ID: 15231310 | Fulltext

Quantitative analysis of the number of antigens immobilized on a glass surface by AFM.

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Kim H, Tsuruta S, Arakawa H, Osada T, and Ikai A

Ultramicroscopy 100(3-4):203-10, 2004 Aug - Who cited this? | PubMed ID: 15231311 | Fulltext

[Methods for the analysis of surface adsorbed proteins].

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Ikai A

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 49(11 Suppl):1740-4, 2004 Aug - Who cited this? | PubMed ID: 15377009 | Fulltext

High sensitivity detection of protein molecules picked up on a probe of atomic force microscope based on the fluorescence detection by a total internal reflection fluorescence microscope.

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Yamada T, Afrin R, Arakawa H, and Ikai A

FEBS letters 569(1-3):59, 2004 Jul 2 - Who cited this? | PubMed ID: 15225609 | Fulltext

Pharmacological assessment of composite arterial conduits using angiography early in the postoperative period.

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Ueyama K, Nishimura K, Ikai A, Koyama T, Nishina T, Ikeda T, and Komeda M

The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi 52(6):279-85, 2004 Jun - Who cited this? | PubMed ID: 15242080 | Fulltext

Pulmonary expression of the hepatocyte growth factor receptor c-Met shifts from medial to intimal layer after cavopulmonary anastomosis.

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Ikai A, Riemer RK, Ma X, Reinhartz O, Hanley FL, and Reddy VM

The Journal of thoracic and cardiovascular surgery 127(5):1442-9, 2004 May - Who cited this? | PubMed ID: 15116006 | Fulltext

Hypoxic pulmonary vasoconstriction disappears in a rabbit model of cavopulmonary shunt.

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Ikai A, Shirai M, Nishimura K, Ikeda T, Kameyama T, Ueyama K, and Komeda M

The Journal of thoracic and cardiovascular surgery 127(5):1450-7, 2004 May - Who cited this? | PubMed ID: 15116007 | Fulltext

Fetal development of vomeronasal system in the goat.

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Takigami S, Wakabayashi Y, Ohsako S, Ohkura S, Okamura H, Ikai A, Ichikawa M, and Osada T

Brain research. Developmental brain research 149(2):113-20, 2004 Apr 19 - Who cited this? | PubMed ID: 15063091 | Fulltext

Structure of bovine carbonic anhydrase II at 1.95 A resolution.

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Saito R, Sato T, Ikai A, and Tanaka N

Acta crystallographica. Section D, Biological crystallography 60(Pt 4):792-5, 2004 Apr - Who cited this? | PubMed ID: 15039588 | Fulltext

Dynamics of a partially stretched protein molecule studied using an atomic force microscope.

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Okajima T, Arakawa H, Alam MT, Sekiguchi H, and Ikai A

Biophysical chemistry 107(1):51-61, 2004 Jan 1 - Who cited this? | PubMed ID: 14871600 | Fulltext

Clinical laboratory implications of single living cell mRNA analysis.

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Osada T, Uehara H, Kim H, and Ikai A

Advances in clinical chemistry 38:239-57, 2004 - Who cited this? | PubMed ID: 15521194 | Fulltext

Unfolding mechanics of multiple OspA substructures investigated with single molecule force spectroscopy.

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Hertadi R, Gruswitz F, Silver L, Koide A, Koide S, Arakawa H, and Ikai A

Journal of molecular biology 333(5):993-1002, 2003 Nov 7 - Who cited this? | PubMed ID: 14583195 | Fulltext

Specific interaction between GroEL and denatured protein measured by compression-free force spectroscopy.

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Sekiguchi H, Arakawa H, Taguchi H, Ito T, Kokawa R, and Ikai A

Biophysical journal 85(1):484-90, 2003 Jul - Who cited this? | PubMed ID: 12829503 | Fulltext

Inhibition of human pepsin and gastricsin by alpha2-macroglobulin.

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Athauda SB, Nishigai M, Arakawa H, Ikai A, Ukai M, and Takahashi K

Journal of enzyme inhibition and medicinal chemistry 18(3):219-24, 2003 Jun - Who cited this? | PubMed ID: 14506912 | Fulltext

Nano-mechanical methods in biochemistry using atomic force microscopy.

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Ikai A, Afrin R, Sekiguchi H, Okajima T, Alam MT, and Nishida S

Current protein & peptide science 4(3):181-93, 2003 Jun - Who cited this? | PubMed ID: 12769717 | Fulltext

Mapping of the receptor-associated protein (RAP) binding proteins on living fibroblast cells using an atomic force microscope.

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Osada T, Itoh A, and Ikai A

Ultramicroscopy 97(1-4):353-7, 2003 - Who cited this? | PubMed ID: 12801688 | Fulltext

Quantification of cell adhesion force with AFM: distribution of vitronectin receptors on a living MC3T3-E1 cell.

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Kim H, Arakawa H, Osada T, and Ikai A

Ultramicroscopy 97(1-4):359-63, 2003 - Who cited this? | PubMed ID: 12801689 | Fulltext

Extraction of membrane proteins from a living cell surface using the atomic force microscope and covalent crosslinkers.

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Afrin R, Arakawa H, Osada T, and Ikai A

Cell biochemistry and biophysics 39(2):101-17, 2003 - Who cited this? | PubMed ID: 14515017 | Fulltext

Toward mechanical manipulations of cell membranes and membrane proteins using an atomic force microscope: an invited review.

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Ikai A and Afrin R

Cell biochemistry and biophysics 39(3):257-77, 2003 - Who cited this? | PubMed ID: 14716080 | Fulltext

Molecular cloning and structural characterization of the hagfish proteinase inhibitor of the alpha-2-macroglobulin family.

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Idiris A, Ohtsubo K, Yoza K, Osada T, Nakamichi N, Matsumura T, and Ikai A

Journal of protein chemistry 22(1):89-98, 2003 Jan - Who cited this? | PubMed ID: 12739901 | Fulltext

A comparative immunocytochemical study of development and regeneration of chemosensory neurons in the rat vomeronasal system.

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Matsuoka M, Osada T, Yoshida-Matsuoka J, Ikai A, Ichikawa M, Norita M, and Costanzo RM

Brain research 946(1):52-63, 2002 Aug 9 - Who cited this? | PubMed ID: 12133594 | Fulltext

Unfolding mechanics of holo- and apocalmodulin studied by the atomic force microscope.

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Hertadi R and Ikai A

Protein science : a publication of the Protein Society 11(6):1532-8, 2002 Jun - Who cited this? | PubMed ID: 12021451 | Fulltext

The importance of being knotted: effects of the C-terminal knot structure on enzymatic and mechanical properties of bovine carbonic anhydrase II.

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Alam MT, Yamada T, Carlsson U, and Ikai A

FEBS letters 519(1-3):35-40, 2002 May 22 - Who cited this? | PubMed ID: 12023014 | Fulltext

[Mechanical unfolding of proteins by forced stretching].

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Ikai A

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 47(6):690-9, 2002 May - Who cited this? | PubMed ID: 11995336 | Fulltext

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