Please enable Javascript

Labmeeting uses lots of Javascript - basically you can't use the site without it. So please enable Javascript in your browser. If your browser does not support Javascript, we recommend Firefox.

Papers authored by Ieiri I

Collect these papers and discover other ones on Labmeeting. Learn more.

Quantitative Population Pharmacokinetic Analysis of Pravastatin Using an Enterohepatic Circulation Model Combined With Pharmacogenomic Information on SLCO1B1 and ABCC2 Polymorphisms.

+ cite this

+ View Abstract

Ide T, Sasaki T, Maeda K, Higuchi S, Sugiyama Y, and Ieiri I

Journal of clinical pharmacology 49(11):1309-17, 2009 Nov - Who cited this? | PubMed ID: 19776292 | Fulltext

Warfarin-dosing algorithm based on a population pharmacokinetic/pharmacodynamic model combined with Bayesian forecasting.

+ cite this

+ View Abstract

Sasaki T, Tabuchi H, Higuchi S, and Ieiri I

Pharmacogenomics 10(8):1257-66, 2009 Aug - Who cited this? | PubMed ID: 19663670 | Fulltext

Effect of smoking and CYP2D6 polymorphisms on the extent of fluvoxamine-alprazolam interaction in patients with psychosomatic disease.

+ cite this

+ View Abstract

Sugahara H, Maebara C, Ohtani H, Handa M, Ando K, Mine K, Kubo C, Ieiri I, and Sawada Y

European journal of clinical pharmacology 65(7):699-704, 2009 Jul - Who cited this? | PubMed ID: 19225771 | Fulltext

Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs.

+ cite this

+ View Abstract

Ieiri I, Higuchi S, and Sugiyama Y

Expert opinion on drug metabolism & toxicology 5(7):703-29, 2009 Jul - Who cited this? | PubMed ID: 19442037 | Fulltext

Life-threatening toxicities in a patient with UGT1A1*6/*28 and SLCO1B1*15/*15 genotypes after irinotecan-based chemotherapy.

+ cite this

+ View Abstract

Takane H, Kawamoto K, Sasaki T, Moriki K, Moriki K, Kitano H, Higuchi S, Otsubo K, and Ieiri I

Cancer chemotherapy and pharmacology 63(6):1165-9, 2009 May - Who cited this? | PubMed ID: 18998132 | Fulltext

Influence of dosing schedules on toxicity and antitumour effects of combined cisplatin and docetaxel treatment in mice.

+ cite this

+ View Abstract

Kodama A, To H, Kinoshita T, Ieiri I, and Higuchi S

The Journal of pharmacy and pharmacology 61(5):615-21, 2009 May - Who cited this? | PubMed ID: 19406000 | Fulltext

Pharmacogenomics: Inter-ethnic and Intra-ethnic Differences in Pharmacokinetic and Pharmacodynamic Profiles of Clinically Relevant Drugs.

+ cite this

+ View Abstract

Ieiri I and Higuchi S

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 129(2):231-5, 2009 Feb - Who cited this? | PubMed ID: 19182452 | Fulltext

Novel Large-scale Deletion (whole Exon 7) in the ABCC2 Gene in a Patient with the Dubin-Johnson Syndrome.

+ cite this

+ View Abstract

Kanda D, Takagi H, Kawahara Y, Yata Y, Takakusagi T, Hatanaka T, Yoshinaga T, Iesaki K, Kashiwabara K, Higuchi T, Mori M, Hirota T, Higuchi S, and Ieiri I

Drug metabolism and pharmacokinetics 24(5):464-8, 2009 - Who cited this? | PubMed ID: 19881259 | Fulltext

Pharmacokinetic interaction between pravastatin and olmesartan in relation to SLCO1B1 polymorphism.

+ cite this

+ View Abstract

Suwannakul S, Ieiri I, Kimura M, Kawabata K, Kusuhara H, Hirota T, Irie S, Sugiyama Y, and Higuchi S

Journal of human genetics, 2008 Jul 19 - Who cited this? | PubMed ID: 18641915 | Fulltext

Pharmacogenetic characterization of sulfasalazine disposition based on NAT2 and ABCG2 (BCRP) gene polymorphisms in humans.

+ cite this

+ View Abstract

Yamasaki Y, Ieiri I, Kusuhara H, Sasaki T, Kimura M, Tabuchi H, Ando Y, Irie S, Ware J, Nakai Y, Higuchi S, and Sugiyama Y

Clinical pharmacology and therapeutics 84(1):95-103, 2008 Jul - Who cited this? | PubMed ID: 18167504 | Fulltext

Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea.

+ cite this

+ View Abstract

Tanaka M, Kobayashi D, Murakami Y, Ozaki N, Suzuki T, Iwata N, Haraguchi K, Ieiri I, Kinukawa N, Hosoi M, Ohtani H, Sawada Y, and Mine K

The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 11(2):261-7, 2008 Apr - Who cited this? | PubMed ID: 17697394 | Fulltext

Polymorphism in human organic cation transporters and metformin action.

+ cite this

+ View Abstract

Takane H, Shikata E, Otsubo K, Higuchi S, and Ieiri I

Pharmacogenomics 9(4):415-22, 2008 Apr - Who cited this? | PubMed ID: 18384255 | Fulltext

Epigenetic regulation of genes encoding drug-metabolizing enzymes and transporters; DNA methylation and other mechanisms.

+ cite this

+ View Abstract

Hirota T, Takane H, Higuchi S, and Ieiri I

Current drug metabolism 9(1):34-8, 2008 Jan - Who cited this? | PubMed ID: 18220569 | Fulltext

SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers.

+ cite this

+ View Abstract

Ieiri I, Suwannakul S, Maeda K, Uchimaru H, Hashimoto K, Kimura M, Fujino H, Hirano M, Kusuhara H, Irie S, Higuchi S, and Sugiyama Y

Clinical pharmacology and therapeutics 82(5):541-7, 2007 Nov - Who cited this? | PubMed ID: 17460607 | Fulltext

Severe toxicities after irinotecan-based chemotherapy in a patient with lung cancer: a homozygote for the SLCO1B1*15 allele.

+ cite this

+ View Abstract

Takane H, Miyata M, Burioka N, Kurai J, Fukuoka Y, Suyama H, Shigeoka Y, Otsubo K, Ieiri I, and Shimizu E

Therapeutic drug monitoring 29(5):666-8, 2007 Oct - Who cited this? | PubMed ID: 17898662 | Fulltext

Human organic cation transporter (OCT1 and OCT2) gene polymorphisms and therapeutic effects of metformin.

+ cite this

+ View Abstract

Shikata E, Yamamoto R, Takane H, Shigemasa C, Ikeda T, Otsubo K, and Ieiri I

Journal of human genetics 52(2):117-22, 2007 - Who cited this? | PubMed ID: 17111267 | Fulltext

Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy.

+ cite this

+ View Abstract

Ieiri I, Takane H, Hirota T, Otsubo K, and Higuchi S

Expert opinion on drug metabolism & toxicology 2(5):651-74, 2006 Oct - Who cited this? | PubMed ID: 17014387 | Fulltext

Multiple gene polymorphisms and warfarin sensitivity.

+ cite this

Shikata E, Ieiri I, Ishiguro S, Takane H, Ohgi S, and Otsubo K

European journal of clinical pharmacology 62(10):881-3, 2006 Oct - Who cited this? | PubMed ID: 16821005 | Fulltext

Evaluation of in vivo P-glycoprotein function at the blood-brain barrier among MDR1 gene polymorphisms by using 11C-verapamil.

+ cite this

+ View Abstract

Takano A, Kusuhara H, Suhara T, Ieiri I, Morimoto T, Lee YJ, Maeda J, Ikoma Y, Ito H, Suzuki K, and Sugiyama Y

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 47(9):1427-33, 2006 Sep - Who cited this? | PubMed ID: 16954549 | Fulltext

Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril.

+ cite this

+ View Abstract

Maeda K, Ieiri I, Yasuda K, Fujino A, Fujiwara H, Otsubo K, Hirano M, Watanabe T, Kitamura Y, Kusuhara H, and Sugiyama Y

Clinical pharmacology and therapeutics 79(5):427-39, 2006 May - Who cited this? | PubMed ID: 16678545 | Fulltext

Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans.

+ cite this

+ View Abstract

Takahashi H, Wilkinson GR, Nutescu EA, Morita T, Ritchie MD, Scordo MG, Pengo V, Barban M, Padrini R, Ieiri I, Otsubo K, Kashima T, Kimura S, Kijima S, and Echizen H

Pharmacogenetics and genomics 16(2):101-10, 2006 Feb - Who cited this? | PubMed ID: 16424822 | Fulltext

Pharmacogenetic determinants of variability in lipid-lowering response to pravastatin therapy.

+ cite this

+ View Abstract

Takane H, Miyata M, Burioka N, Shigemasa C, Shimizu E, Otsubo K, and Ieiri I

Journal of human genetics 51(9):822-6, 2006 - Who cited this? | PubMed ID: 16917677 | Fulltext

Interaction magnitude, pharmacokinetics and pharmacodynamics of ticlopidine in relation to CYP2C19 genotypic status.

+ cite this

+ View Abstract

Ieiri I, Kimura M, Irie S, Urae A, Otsubo K, and Ishizaki T

Pharmacogenetics and genomics 15(12):851-9, 2005 Dec - Who cited this? | PubMed ID: 16272957 | Fulltext

Rifampin reduces the analgesic effect of transdermal fentanyl.

+ cite this

Takane H, Nosaka A, Wakushima H, Hosokawa K, and Ieiri I

The Annals of pharmacotherapy 39(12):2139-40, 2005 Dec - Who cited this? | PubMed ID: 16288064 | Fulltext

Functional assessment of ABCG2 (BCRP) gene polymorphisms to protein expression in human placenta.

+ cite this

+ View Abstract

Kobayashi D, Ieiri I, Hirota T, Takane H, Maegawa S, Kigawa J, Suzuki H, Nanba E, Oshimura M, Terakawa N, Otsubo K, Mine K, and Sugiyama Y

Drug metabolism and disposition: the biological fate of chemicals 33(1):94-101, 2005 Jan - Who cited this? | PubMed ID: 15475413 | Fulltext

Allelic expression imbalance of the human CYP3A4 gene and individual phenotypic status.

+ cite this

+ View Abstract

Hirota T, Ieiri I, Takane H, Maegawa S, Hosokawa M, Kobayashi K, Chiba K, Nanba E, Oshimura M, Sato T, Higuchi S, and Otsubo K

Human molecular genetics 13(23):2959-69, 2004 Dec 1 - Who cited this? | PubMed ID: 15459178 | Fulltext

Haplotype-oriented genetic analysis and functional assessment of promoter variants in the MDR1 (ABCB1) gene.

+ cite this

+ View Abstract

Takane H, Kobayashi D, Hirota T, Kigawa J, Terakawa N, Otsubo K, and Ieiri I

The Journal of pharmacology and experimental therapeutics 311(3):1179-87, 2004 Dec - Who cited this? | PubMed ID: 15280437 | Fulltext

Functional analysis of single nucleotide polymorphisms of hepatic organic anion transporter OATP1B1 (OATP-C).

+ cite this

+ View Abstract

Iwai M, Suzuki H, Ieiri I, Otsubo K, and Sugiyama Y

Pharmacogenetics 14(11):749-57, 2004 Nov - Who cited this? | PubMed ID: 15564882 | Fulltext

Functional analysis of SNPs variants of BCRP/ABCG2.

+ cite this

+ View Abstract

Kondo C, Suzuki H, Itoda M, Ozawa S, Sawada J, Kobayashi D, Ieiri I, Mine K, Ohtsubo K, and Sugiyama Y

Pharmaceutical research 21(10):1895-903, 2004 Oct - Who cited this? | PubMed ID: 15553238 | Fulltext

Characterization of the cellular localization, expression level, and function of SNP variants of MRP2/ABCC2.

+ cite this

+ View Abstract

Hirouchi M, Suzuki H, Itoda M, Ozawa S, Sawada J, Ieiri I, Ohtsubo K, and Sugiyama Y

Pharmaceutical research 21(5):742-8, 2004 May - Who cited this? | PubMed ID: 15180328 | Fulltext

5'-Flanking region polymorphisms of CYP2C9 and their relationship to S-warfarin metabolism in white and Japanese patients.

+ cite this

+ View Abstract

Takahashi H, Ieiri I, Wilkinson GR, Mayo G, Kashima T, Kimura S, Otsubo K, and Echizen H

Blood 103(8):3055-7, 2004 Apr 15 - Who cited this? | PubMed ID: 15070684 | Fulltext

Association of pharmacokinetic (CYP2C9) and pharmacodynamic (factors II, VII, IX, and X; proteins S and C; and gamma-glutamyl carboxylase) gene variants with warfarin sensitivity.

+ cite this

+ View Abstract

Shikata E, Ieiri I, Ishiguro S, Aono H, Inoue K, Koide T, Ohgi S, and Otsubo K

Blood 103(7):2630-5, 2004 Apr 1 - Who cited this? | PubMed ID: 14656880 | Fulltext

The MDR1 (ABCB1) gene polymorphism and its clinical implications.

+ cite this

+ View Abstract

Ieiri I, Takane H, and Otsubo K

Clinical pharmacokinetics 43(9):553-76, 2004 - Who cited this? | PubMed ID: 15217301 | Fulltext

Formation of highly analgesic morphine-6-glucuronide following physiologic concentration of morphine in human brain.

+ cite this

+ View Abstract

Yamada H, Ishii K, Ishii Y, Ieiri I, Nishio S, Morioka T, and Oguri K

The Journal of toxicological sciences 28(5):395-401, 2003 Dec - Who cited this? | PubMed ID: 14746343 | Fulltext

A CYP2D6 phenotype-genotype mismatch in Japanese psychiatric patients.

+ cite this

+ View Abstract

Ieiri I, Yamada S, Seto K, Morita T, Kaneda T, Mamiya K, Tashiro N, Higuchi S, and Otsubo K

Pharmacopsychiatry 36(5):192-6, 2003 Sep - Who cited this? | PubMed ID: 14571354 | Fulltext

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics.

+ cite this

+ View Abstract

Nishizato Y, Ieiri I, Suzuki H, Kimura M, Kawabata K, Hirota T, Takane H, Irie S, Kusuhara H, Urasaki Y, Urae A, Higuchi S, Otsubo K, and Sugiyama Y

Clinical pharmacology and therapeutics 73(6):554-65, 2003 Jun - Who cited this? | PubMed ID: 12811365 | Fulltext

Sequence variability and candidate gene analysis in two cancer patients with complex clinical outcomes during morphine therapy.

+ cite this

+ View Abstract

Hirota T, Ieiri I, Takane H, Sano H, Kawamoto K, Aono H, Yamasaki A, Takeuchi H, Masada M, Shimizu E, Higuchi S, and Otsubo K

Drug metabolism and disposition: the biological fate of chemicals 31(5):677-80, 2003 May - Who cited this? | PubMed ID: 12695358 | Fulltext

[Simultaneous determination of carbaryl and propanil in human serum and urine by on-line column-switching technique followed by automatic reversed-phase HPLC].

+ cite this

+ View Abstract

Ichinoki S, Takido N, Fujii Y, Morita T, Ieiri I, Otsubo K, and Saitoh N

Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 16(2):171-8, 2003 Apr - Who cited this? | PubMed ID: 12856628 | Fulltext

The antiplatelet aggregation effects of aspirin suppositories.

+ cite this

+ View Abstract

Nakayasu H, Maeda M, Soda T, Iijima K, Ishimoto M, Ieiri I, Tabuchi F, Otsubo K, and Nakashima K

Cerebrovascular diseases (Basel, Switzerland) 16(1):31-5, 2003 - Who cited this? | PubMed ID: 12766359 | Fulltext

Neurotoxicity induced by tacrolimus after liver transplantation: relation to genetic polymorphisms of the ABCB1 (MDR1) gene.

+ cite this

+ View Abstract

Yamauchi A, Ieiri I, Kataoka Y, Tanabe M, Nishizaki T, Oishi R, Higuchi S, Otsubo K, and Sugimachi K

Transplantation 74(4):571-2, 2002 Aug 27 - Who cited this? | PubMed ID: 12352921 | Fulltext

Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

+ cite this

+ View Abstract

Kurata Y, Ieiri I, Kimura M, Morita T, Irie S, Urae A, Ohdo S, Ohtani H, Sawada Y, Higuchi S, and Otsubo K

Clinical pharmacology and therapeutics 72(2):209-19, 2002 Aug - Who cited this? | PubMed ID: 12189368 | Fulltext

Polymorphism of MDR1 gene in healthy japanese subjects: a novel SNP with an amino acid substitution (Glu108Lys).

+ cite this

+ View Abstract

Honda T, Dan Y, Koyabu N, Ieiri I, Otsubo K, Higuchi S, Ohtani H, and Sawada Y

Drug metabolism and pharmacokinetics 17(5):479-81, 2002 - Who cited this? | PubMed ID: 15618700 | Fulltext

Comparison of the kinetic disposition of and serum gastrin change by lansoprazole versus rabeprazole during an 8-day dosing scheme in relation to CYP2C19 polymorphism.

+ cite this

+ View Abstract

Ieiri I, Kishimoto Y, Okochi H, Momiyama K, Morita T, Kitano M, Morisawa T, Fukushima Y, Nakagawa K, Hasegawa J, Otsubo K, and Ishizaki T

European journal of clinical pharmacology 57(6-7):485-92, 2001 Sep - Who cited this? | PubMed ID: 11699613 | Fulltext

Genetic polymorphisms and functional characterization of the 5'-flanking region of the human CYP2C9 gene: in vitro and in vivo studies.

+ cite this

+ View Abstract

Shintani M, Ieiri I, Inoue K, Mamiya K, Ninomiya H, Tashiro N, Higuchi S, and Otsubo K

Clinical pharmacology and therapeutics 70(2):175-82, 2001 Aug - Who cited this? | PubMed ID: 11503012 | Fulltext

Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene.

+ cite this

+ View Abstract

Tanabe M, Ieiri I, Nagata N, Inoue K, Ito S, Kanamori Y, Takahashi M, Kurata Y, Kigawa J, Higuchi S, Terakawa N, and Otsubo K

The Journal of pharmacology and experimental therapeutics 297(3):1137-43, 2001 Jun - Who cited this? | PubMed ID: 11356939 | Fulltext

P-hydroxylation of phenobarbital: relationship to (S)-mephenytoin hydroxylation (CYP2C19) polymorphism.

+ cite this

+ View Abstract

Hadama A, Ieiri I, Morita T, Kimura M, Urae A, Irie S, Kaneda T, Mamiya K, Tashiro N, Higuchi S, and Otsubo K

Therapeutic drug monitoring 23(2):115-8, 2001 Apr - Who cited this? | PubMed ID: 11294510 | Fulltext

Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects.

+ cite this

Ito S, Ieiri I, Tanabe M, Suzuki A, Higuchi S, and Otsubo K

Pharmacogenetics 11(2):175-84, 2001 Mar - Who cited this? | PubMed ID: 11266082 | Fulltext

Phenytoin intoxication induced by fluvoxamine.

+ cite this

+ View Abstract

Mamiya K, Kojima K, Yukawa E, Higuchi S, Ieiri I, Ninomiya H, and Tashiro N

Therapeutic drug monitoring 23(1):75-7, 2001 Feb - Who cited this? | PubMed ID: 11206048 | Fulltext

Catalytic activity of three variants (Ile, Leu, and Thr) at amino acid residue 359 in human CYP2C9 gene and simultaneous detection using single-strand conformation polymorphism analysis.

+ cite this

+ View Abstract

Ieiri I, Tainaka H, Morita T, Hadama A, Mamiya K, Hayashibara M, Ninomiya H, Ohmori S, Kitada M, Tashiro N, Higuchi S, and Otsubo K

Therapeutic drug monitoring 22(3):237-44, 2000 Jun - Who cited this? | PubMed ID: 10850388 | Fulltext

Genetic polymorphism of the CYP2C subfamily and excessive serum phenytoin concentration with central nervous system intoxication.

+ cite this

+ View Abstract

Ninomiya H, Mamiya K, Matsuo S, Ieiri I, Higuchi S, and Tashiro N

Therapeutic drug monitoring 22(2):230-2, 2000 Apr - Who cited this? | PubMed ID: 10774639 | Fulltext

Search Google Scholar for Ieiri I

Join Labmeeting

Organize and search your PDF collection
Collect papers
Search millions of papers
Keep up to date with paper alerts
Read your papers from anywhere
Recommend papers to colleagues
Manage your lab

Labmeeting is a web service for researchers. Sign up with your academic email address.

Individuals or corporations not affiliated with an academic institution can request a trial subscription.

Got a question?
The Labmeeting Network
has the answer.
Ask scientists at top universities like Harvard, Stanford, and MIT for their expert opinion!