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Papers authored by Humbles A

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Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells.

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Jones TG, Hallgren J, Humbles A, Burwell T, Finkelman FD, Alcaide P, Austen KF, and Gurish MF

Journal of immunology (Baltimore, Md. : 1950) 183(8):5251-60, 2009 Oct 15 - Who cited this? | PubMed ID: 19783672 | Fulltext

CCR3 is a target for age-related macular degeneration diagnosis and therapy.

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Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG,

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Nature 460(7252):225-30, 2009 Jul 9 - Who cited this? | PubMed ID: 19525930 | Fulltext

Capillary defects and exaggerated inflammatory response in the airways of EphA2-deficient mice.

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Okazaki T, Ni A, Baluk P, Ayeni OA, Kearley J, Coyle AJ, Humbles A, and McDonald DM

The American journal of pathology 174(6):2388-99, 2009 Jun - Who cited this? | PubMed ID: 19443703 | Fulltext

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis.

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Lee CG, Hartl D, Lee GR, Koller B, Matsuura H, Da Silva CA, Sohn MH, Cohn L, Homer RJ, Kozhich AA, Humbles A, Kearley J, Coyle A, Chupp G, Reed J, Flavell RA,

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The Journal of experimental medicine 206(5):1149-66, 2009 May 11 - Who cited this? | PubMed ID: 19414556 | Fulltext

Macrophage impairment underlies airway occlusion in primary respiratory syncytial virus bronchiolitis.

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Reed JL, Brewah YA, Delaney T, Welliver T, Burwell T, Benjamin E, Kuta E, Kozhich A, McKinney L, Suzich J, Kiener PA, Avendano L, Velozo L, Humbles A, Welliver RC, and Coyle AJ

The Journal of infectious diseases 198(12):1783-93, 2008 Dec 15 - Who cited this? | PubMed ID: 18980502 | Fulltext

Strain-specific requirement for eosinophils in the recruitment of T cells to the lung during the development of allergic asthma.

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Walsh ER, Sahu N, Kearley J, Benjamin E, Kang BH, Humbles A, and August A

The Journal of experimental medicine 205(6):1285, 2008 Jun 9 - Who cited this? | PubMed ID: 18490489 | Fulltext

Pulmonary CXCR2 regulates VCAM-1 and antigen-induced recruitment of mast cell progenitors.

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Hallgren J, Jones TG, Abonia JP, Xing W, Humbles A, Austen KF, and Gurish MF

Proceedings of the National Academy of Sciences of the United States of America 104(51):20478-83, 2007 Dec 18 - Who cited this? | PubMed ID: 18077323 | Fulltext

C5 modulates airway hyperreactivity and pulmonary eosinophilia during enhanced respiratory syncytial virus disease by decreasing C3a receptor expression.

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Melendi GA, Hoffman SJ, Karron RA, Irusta PM, Laham FR, Humbles A, Schofield B, Pan CH, Rabold R, Thumar B, Thumar A, Gerard NP, Mitzner W, Barnum SR, Gerard C, Kleeberger SR,

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Journal of virology 81(2):991-9, 2007 Jan - Who cited this? | PubMed ID: 17079327 | Fulltext

Deletion of CCR1 attenuates pathophysiologic responses during respiratory syncytial virus infection.

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Miller AL, Gerard C, Schaller M, Gruber AD, Humbles AA, and Lukacs NW

Journal of immunology (Baltimore, Md. : 1950) 176(4):2562-7, 2006 Feb 15 - Who cited this? | PubMed ID: 16456018 | Fulltext

Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle.

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Abonia JP, Friend DS, Austen WG, Moore FD, Carroll MC, Chan R, Afnan J, Humbles A, Gerard C, Knight P, Kanaoka Y, Yasuda S, Morokawa N, Austen KF, Stevens RL, and Gurish MF

Journal of immunology (Baltimore, Md. : 1950) 174(11):7285-91, 2005 Jun 1 - Who cited this? | PubMed ID: 15905575 | Fulltext

Respiratory syncytial virus-induced exaggeration of allergic airway disease is dependent upon CCR1-associated immune responses.

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John AE, Gerard CJ, Schaller M, Miller AL, Berlin AA, Humbles AA, and Lukacs NW

European journal of immunology 35(1):108-16, 2005 Jan - Who cited this? | PubMed ID: 15593301 | Fulltext

A critical role for eosinophils in allergic airways remodeling.

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Humbles AA, Lloyd CM, McMillan SJ, Friend DS, Xanthou G, McKenna EE, Ghiran S, Gerard NP, Yu C, Orkin SH, and Gerard C

Science (New York, N.Y.) 305(5691):1776-9, 2004 Sep 17 - Who cited this? | PubMed ID: 15375268 | Fulltext

The anaphylatoxin C3a downregulates the Th2 response to epicutaneously introduced antigen.

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Kawamoto S, Yalcindag A, Laouini D, Brodeur S, Bryce P, Lu B, Humbles AA, Oettgen H, Gerard C, and Geha RS

The Journal of clinical investigation 114(3):399-407, 2004 Aug - Who cited this? | PubMed ID: 15286806 | Fulltext

C5L2, a nonsignaling C5A binding protein.

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Okinaga S, Slattery D, Humbles A, Zsengeller Z, Morteau O, Kinrade MB, Brodbeck RM, Krause JE, Choe HR, Gerard NP, and Gerard C

Biochemistry 42(31):9406-15, 2003 Aug 12 - Who cited this? | PubMed ID: 12899627 | Fulltext

Essential role for the C5a receptor in regulating the effector phase of synovial infiltration and joint destruction in experimental arthritis.

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Grant EP, Picarella D, Burwell T, Delaney T, Croci A, Avitahl N, Humbles AA, Gutierrez-Ramos JC, Briskin M, Gerard C, and Coyle AJ

The Journal of experimental medicine 196(11):1461-71, 2002 Dec 2 - Who cited this? | PubMed ID: 12461081 | Fulltext

CCR3 is required for tissue eosinophilia and larval cytotoxicity after infection with Trichinella spiralis.

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Gurish MF, Humbles A, Tao H, Finkelstein S, Boyce JA, Gerard C, Friend DS, and Austen KF

Journal of immunology (Baltimore, Md. : 1950) 168(11):5730-6, 2002 Jun 1 - Who cited this? | PubMed ID: 12023373 | Fulltext

CCR3 is essential for skin eosinophilia and airway hyperresponsiveness in a murine model of allergic skin inflammation.

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Ma W, Bryce PJ, Humbles AA, Laouini D, Yalcindag A, Alenius H, Friend DS, Oettgen HC, Gerard C, and Geha RS

The Journal of clinical investigation 109(5):621-8, 2002 Mar - Who cited this? | PubMed ID: 11877470 | Fulltext

The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness.

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Humbles AA, Lu B, Friend DS, Okinaga S, Lora J, Al-Garawi A, Martin TR, Gerard NP, and Gerard C

Proceedings of the National Academy of Sciences of the United States of America 99(3):1479-84, 2002 Feb 5 - Who cited this? | PubMed ID: 11830666 | Fulltext

Macrophage inflammatory protein-1alpha uses a novel receptor for primitive hemopoietic cell inhibition.

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Ottersbach K, Cook DN, Kuziel WA, Humbles A, Lu B, Gerard C, Proudfoot AE, and Graham GJ

Blood 98(12):3476-8, 2001 Dec 1 - Who cited this? | PubMed ID: 11719391 | Fulltext

A role for the C3a anaphylatoxin receptor in the effector phase of asthma.

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Humbles AA, Lu B, Nilsson CA, Lilly C, Israel E, Fujiwara Y, Gerard NP, and Gerard C

Nature 406(6799):998-1001, 2000 Aug 31 - Who cited this? | PubMed ID: 10984054 | Fulltext

Lymph node trafficking and antigen presentation by endobronchial eosinophils.

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Shi HZ, Humbles A, Gerard C, Jin Z, and Weller PF

The Journal of clinical investigation 105(7):945-53, 2000 Apr - Who cited this? | PubMed ID: 10749574 | Fulltext

Structure and function of the murine chemokine receptor CXCR3.

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Lu B, Humbles A, Bota D, Gerard C, Moser B, Soler D, Luster AD, and Gerard NP

European journal of immunology 29(11):3804-12, 1999 Nov - Who cited this? | PubMed ID: 10556837 | Fulltext

Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis.

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Bozza M, Satoskar AR, Lin G, Lu B, Humbles AA, Gerard C, and David JR

The Journal of experimental medicine 189(2):341-6, 1999 Jan 18 - Who cited this? | PubMed ID: 9892616 | Fulltext

Kinetics of eotaxin generation and its relationship to eosinophil accumulation in allergic airways disease: analysis in a guinea pig model in vivo.

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Humbles AA, Conroy DM, Marleau S, Rankin SM, Palframan RT, Proudfoot AE, Wells TN, Li D, Jeffery PK, Griffiths-Johnson DA, Williams TJ, and Jose PJ

The Journal of experimental medicine 186(4):601-12, 1997 Aug 18 - Who cited this? | PubMed ID: 9254658 | Fulltext

The role of the eosinophil-selective chemokine, eotaxin, in allergic and non-allergic airways inflammation.

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Conroy DM, Humbles AA, Rankin SM, Palframan RT, Collins PD, Griffiths-Johnson DA, Jose PJ, and Williams TJ

Memorias do Instituto Oswaldo Cruz 92 Suppl 2:183-91, 1997 - Who cited this? | PubMed ID: 9698931 | Fulltext

Formoterol on airway smooth muscle and human lung mast cells: a comparison with salbutamol and salmeterol.

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Nials AT, Ball DI, Butchers PR, Coleman RA, Humbles AA, Johnson M, and Vardey CJ

European journal of pharmacology 251(2-3):127-35, 1994 Jan 14 - Who cited this? | PubMed ID: 8149969 | Fulltext

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