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Papers authored by Hughes AD

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Impaired recovery of intracellular calcium and force after activation in isolated myometrial and subcutaneous resistance arteries from women with preeclampsia.

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Wimalasundera RC, Wijetunge S, Thom SM, Regan L, and Hughes AD

Journal of hypertension 28(3):568-74, 2010 Mar - Who cited this? | PubMed ID: 20090555 | Fulltext

Calcium channel regulation in vascular smooth muscle cells: synergistic effects of statins and calcium channel blockers.

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Clunn GF, Sever PS, and Hughes AD

International journal of cardiology 139(1):2-6, 2010 Feb 18 - Who cited this? | PubMed ID: 19523699 | Fulltext

The arterial reservoir pressure increases with aging and is the major determinant of the aortic augmentation index.

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Davies JE, Baksi J, Francis DP, Hadjiloizou N, Whinnett ZI, Manisty CH, Aguado-Sierra J, Foale RA, Malik IS, Tyberg JV, Parker KH, Mayet J, and Hughes AD

American journal of physiology. Heart and circulatory physiology 298(2):H580-6, 2010 Feb - Who cited this? | PubMed ID: 20008272 | Fulltext

Caution using brachial systolic pressure to calibrate radial tonometric pressure waveforms: lessons from invasive study.

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Davies JE, Shanmuganathan M, Francis DP, Mayet J, Hackett DR, and Hughes AD

Hypertension 55(1):e4, 2010 Jan - Who cited this? | PubMed ID: 19948982 | Fulltext

Identification of immune parameters to differentiate disease states among sheep infected with Mycobacterium avium subsp. paratuberculosis.

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Gillan S, O'Brien R, Hughes AD, and Griffin JF

Clinical and vaccine immunology : CVI 17(1):108-17, 2010 Jan - Who cited this? | PubMed ID: 19923568 | Fulltext

Attenuation of microvascular function in those with cardiovascular disease is similar in patients of Indian Asian and European descent.

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Strain WD, Hughes AD, Mayet J, Wright AR, Kooner J, Chaturvedi N, and Shore AC

BMC cardiovascular disorders 10:3, 2010 - Who cited this? | PubMed ID: 20078879 | Fulltext

A meta-analysis of the mechanism of blood pressure change with aging.

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Baksi AJ, Treibel TA, Davies JE, Hadjiloizou N, Foale RA, Parker KH, Francis DP, Mayet J, and Hughes AD

Journal of the American College of Cardiology 54(22):2087-92, 2009 Nov 24 - Who cited this? | PubMed ID: 19926018 | Fulltext

Atorvastatin treatment is associated with less augmentation of the carotid pressure waveform in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT).

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Manisty C, Mayet J, Tapp RJ, Sever PS, Poulter N, McG Thom SA, Hughes AD, and ASCOT Investigators

Hypertension 54(5):1009-13, 2009 Nov - Who cited this? | PubMed ID: 19720956 | Fulltext

NS11021, a novel opener of large-conductance Ca(2+)-activated K(+) channels, enhances erectile responses in rats.

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Kun A, Matchkov VV, Stankevicius E, Nardi A, Hughes AD, Kirkeby HJ, Demnitz J, and Simonsen U

British journal of pharmacology 158(6):1465-76, 2009 Nov - Who cited this? | PubMed ID: 19845682 | Fulltext

Computational analysis of oxygen transport in the retinal arterial network.

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Liu D, Wood NB, Witt N, Hughes AD, Thom SA, and Xu XY

Current eye research 34(11):945-56, 2009 Nov - Who cited this? | PubMed ID: 19958111 | Fulltext

Effects of blood pressure lowering and intensive glucose control on the incidence and progression of retinopathy in patients with type 2 diabetes mellitus: a randomised controlled trial.

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Beulens JW, Patel A, Vingerling JR, Cruickshank JK, Hughes AD, Stanton A, Lu J, McG Thom SA, Grobbee DE, Stolk RP, AdRem project team, and ADVANCE management committee

Diabetologia 52(10):2027-36, 2009 Oct - Who cited this? | PubMed ID: 19633827 | Fulltext

Differences in the magnitude of wave reflection account for differential effects of amlodipine- versus atenolol-based regimens on central blood pressure: an Anglo-Scandinavian cardiac outcome trial substudy.

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Manisty CH, Zambanini A, Parker KH, Davies JE, Francis DP, Mayet J, McG Thom SA, Hughes AD, and Anglo-Scandinavian Cardiac Outcome Trial Investigators

Hypertension 54(4):724-30, 2009 Oct - Who cited this? | PubMed ID: 19704107 | Fulltext

Comparison of the retinal microvasculature in European and African-Caribbean people with diabetes.

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Mahal S, Strain WD, Martinez-Perez ME, Thom SA, Chaturvedi N, and Hughes AD

Clinical science (London, England : 1979) 117(6):229-36, 2009 Sep - Who cited this? | PubMed ID: 19173676 | Fulltext

Dynamic CO2 therapy in periodic breathing: a modeling study to determine optimal timing and dosage regimes.

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Mebrate Y, Willson K, Manisty CH, Baruah R, Mayet J, Hughes AD, Parker KH, and Francis DP

Journal of applied physiology (Bethesda, Md. : 1985) 107(3):696-706, 2009 Sep - Who cited this? | PubMed ID: 19628721 | Fulltext

[In Process Citation].

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Davies J, Parker KH, Francis DP, Hughes AD, and Mayet J

Heart (British Cardiac Society) 95(11):937-8, 2009 Jun - Who cited this? | PubMed ID: 19443480 | Fulltext

Serum amyloid A, C-reactive protein, and retinal microvascular changes in hypertensive diabetic and nondiabetic individuals: an Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) substudy.

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Stettler C, Witt N, Tapp RJ, Thom S, Allemann S, Tillin T, Stanton A, O'Brien E, Poulter N, Gallimore JR, Hughes AD, and Chaturvedi N

Diabetes care 32(6):1098-100, 2009 Jun - Who cited this? | PubMed ID: 19244088 | Fulltext

Pharmacological properties of TD-6301, a novel bladder selective muscarinic receptor antagonist.

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McNamara A, Pulido-Rios MT, Sweazey S, Obedencio GP, Thibodeaux H, Renner T, Armstrong SR, Steinfeld T, Hughes AD, Wilson RD, Jasper JR, Mammen M, and Hegde SS

European journal of pharmacology 605(1-3):145-52, 2009 Mar 1 - Who cited this? | PubMed ID: 19168050 | Fulltext

Stress phase angle depicts differences in coronary artery hemodynamics due to changes in flow and geometry after percutaneous coronary intervention.

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Torii R, Wood NB, Hadjiloizou N, Dowsey AW, Wright AR, Hughes AD, Davies J, Francis DP, Mayet J, Yang GZ, Thom SA, and Xu XY

American journal of physiology. Heart and circulatory physiology 296(3):H765-76, 2009 Mar - Who cited this? | PubMed ID: 19151251 | Fulltext

Efficacy of novel lipid-formulated whole bacterial cell vaccines against Mycobacterium avium subsp. paratuberculosis in sheep.

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Griffin JF, Hughes AD, Liggett S, Farquhar PA, Mackintosh CG, and Bakker D

Vaccine 27(6):911-8, 2009 Feb 5 - Who cited this? | PubMed ID: 19059295 | Fulltext

Computational Modeling of LDL and Albumin Transport in an In Vivo CT Image-Based Human Right Coronary Artery.

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Sun N, Torii R, Wood NB, Hughes AD, Thom SA, and Xu XY

Journal of biomechanical engineering 131(2):021003, 2009 Feb - Who cited this? | PubMed ID: 19102562 | Fulltext

Evidence of improved regional myocardial function in patients with chronic stable angina and apparent normal ventricular function-a tissue Doppler study before and after percutaneous coronary intervention.

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Diller GP, Wasan BS, Thom SA, Foale RA, Hughes AD, Francis DP, and Mayet J

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 22(2):177-82, 2009 Feb - Who cited this? | PubMed ID: 19022622 | Fulltext

Determinants of retinal microvascular architecture in normal subjects.

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Hughes AD, Wong TY, Witt N, Evans R, Thom SA, Klein BE, Chaturvedi N, and Klein R

Microcirculation (New York, N.Y. : 1994) 16(2):159-66, 2009 Feb - Who cited this? | PubMed ID: 19206002 | Fulltext

Wave intensity analysis and the development of the reservoir-wave approach.

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Tyberg JV, Davies JE, Wang Z, Whitelaw WA, Flewitt JA, Shrive NG, Francis DP, Hughes AD, Parker KH, and Wang JJ

Medical & biological engineering & computing 47(2):221-32, 2009 Feb - Who cited this? | PubMed ID: 19189147 | Fulltext

Forward and backward waves in the arterial system: impedance or wave intensity analysis?.

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Hughes AD and Parker KH

Medical & biological engineering & computing 47(2):207-10, 2009 Feb - Who cited this? | PubMed ID: 19198913 | Fulltext

Impact of statin therapy on central aortic pressures and hemodynamics: principal results of the Conduit Artery Function Evaluation-Lipid-Lowering Arm (CAFE-LLA) Study.

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Williams B, Lacy PS, Cruickshank JK, Collier D, Hughes AD, Stanton A, Thom S, Thurston H, and CAFE and ASCOT Investigators

Circulation 119(1):53-61, 2009 Jan 6 - Who cited this? | PubMed ID: 19103995 | Fulltext

What is the role of the aorta in directing coronary blood flow?.

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Davies JE, Parker KH, Francis DP, Hughes AD, and Mayet J

Heart (British Cardiac Society) 94(12):1545-7, 2008 Dec - Who cited this? | PubMed ID: 18632832 | Fulltext

Efficiency, reproducibility and agreement of five different hemodynamic measures for optimization of cardiac resynchronization therapy.

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Whinnett ZI, Davies JE, Nott G, Willson K, Manisty CH, Peters NS, Kanagaratnam P, Davies DW, Hughes AD, Mayet J, and Francis DP

International journal of cardiology 129(2):216-26, 2008 Sep 26 - Who cited this? | PubMed ID: 17881070 | Fulltext

Ethnicity and Left Ventricular Diastolic Function in Hypertension An ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) Substudy.

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Sharp A, Tapp R, Francis DP, McG Thom SA, Hughes AD, Stanton AV, Zambanini A, Chaturvedi N, Byrd S, Poulter NR, Sever PS, and Mayet J

Journal of the American College of Cardiology 52(12):1015-21, 2008 Sep 16 - Who cited this? | PubMed ID: 18786484 | Fulltext

Ethnic differences in retinal microvascular structure.

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Tillin T, Evans RM, Witt NW, Sharp PS, McKeigue PM, Chaturvedi N, and Hughes AD

Diabetologia 51(9):1719-22, 2008 Sep - Who cited this? | PubMed ID: 18626625 | Fulltext

Differences in cardiac microcirculatory wave patterns between the proximal left mainstem and proximal right coronary artery.

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Hadjiloizou N, Davies JE, Malik IS, Aguado-Sierra J, Willson K, Foale RA, Parker KH, Hughes AD, Francis DP, and Mayet J

American journal of physiology. Heart and circulatory physiology 295(3):H1198-205, 2008 Sep - Who cited this? | PubMed ID: 18641272 | Fulltext

Effect of antihypertensive treatment on retinal microvascular changes in hypertension.

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Hughes AD, Stanton AV, Jabbar AS, Chapman N, Martinez-Perez ME, and McG Thom SA

Journal of hypertension 26(8):1703-7, 2008 Aug - Who cited this? | PubMed ID: 18622251 | Fulltext

Induction of oscillatory ventilation pattern using dynamic modulation of heart rate through a pacemaker.

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Manisty CH, Willson K, Davies JE, Whinnett ZI, Baruah R, Mebrate Y, Kanagaratnam P, Peters NS, Hughes AD, Mayet J, and Francis DP

American journal of physiology. Regulatory, integrative and comparative physiology 295(1):R219-27, 2008 Jul - Who cited this? | PubMed ID: 18463195 | Fulltext

Peripheral augmentation index and wave reflection in the radial artery.

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Hughes AD, Davies JE, Francis D, Mayet J, and Parker KH

Hypertension 51(6):e45-6, 2008 Jun - Who cited this? | PubMed ID: 18443231 | Fulltext

Effects of elastic compression stockings on wall shear stress in deep and superficial veins of the calf.

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Downie SP, Raynor SM, Firmin DN, Wood NB, Thom SA, Hughes AD, Parker KH, Wolfe JH, and Xu XY

American journal of physiology. Heart and circulatory physiology 294(5):H2112-20, 2008 May - Who cited this? | PubMed ID: 18326802 | Fulltext

The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression.

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Achour M, Jacq X, Rondé P, Alhosin M, Charlot C, Chataigneau T, Jeanblanc M, Macaluso M, Giordano A, Hughes AD, Schini-Kerth VB, and Bronner C

Oncogene 27(15):2187-97, 2008 Apr 3 - Who cited this? | PubMed ID: 17934516 | Fulltext

Retinal vascular lesions in patients of Caucasian and Asian origin with type 2 diabetes: baseline results from the ADVANCE Retinal Measurements (AdRem) study.

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Stolk RP, van Schooneveld MJ, Cruickshank JK, Hughes AD, Stanton A, Lu J, Patel A, Thom SA, Grobbee DE, Vingerling JR, and AdRem Project Team and ADVANCE Management Committee

Diabetes care 31(4):708-13, 2008 Apr - Who cited this? | PubMed ID: 18184903 | Fulltext

The atrioventricular delay of cardiac resynchronization can be optimized hemodynamically during exercise and predicted from resting measurements.

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Whinnett ZI, Briscoe C, Davies JE, Willson K, Manisty CH, Davies DW, Peters NS, Kanagaratnam P, Hughes AD, Mayet J, and Francis DP

Heart rhythm : the official journal of the Heart Rhythm Society 5(3):378-86, 2008 Mar - Who cited this? | PubMed ID: 18313595 | Fulltext

A pattern recognition based fluorescence quenching assay for the detection and identification of nitrated explosive analytes.

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Hughes AD, Glenn IC, Patrick AD, Ellington A, and Anslyn EV

Chemistry (Weinheim an der Bergstrasse, Germany) 14(6):1822, 2008 - Who cited this? | PubMed ID: 18161712 | Fulltext

Reservoir-wave separation and wave intensity analysis applied to carotid arteries: A hybrid 1D model to understand haemodynamics.

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Aguado-Sierra J, Davies JE, Hadjiloizou N, Francis D, Mayet J, Hughes AD, and Parker KH

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 1:1381-4, 2008 - Who cited this? | PubMed ID: 19162925 | Fulltext

Left ventricular hypertrophy induced by aortic banding impairs relaxation of isolated coronary arteries.

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McGoldrick RB, Kingsbury M, Turner MA, Sheridan DJ, and Hughes AD

Clinical science (London, England : 1979) 113(12):473-8, 2007 Dec - Who cited this? | PubMed ID: 17635104 | Fulltext

Impact of size at birth on the microvasculature: the Avon Longitudinal Study of Parents and Children.

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Tapp RJ, Williams C, Witt N, Chaturvedi N, Evans R, Thom SA, Hughes AD, and Ness A

Pediatrics 120(5), 2007 Nov - Who cited this? | PubMed ID: 17974715 | Fulltext

Influence of pulsatile flow on LDL transport in the arterial wall.

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Sun N, Wood NB, Hughes AD, Thom SA, and Xu XY

Annals of biomedical engineering 35(10):1782-90, 2007 Oct - Who cited this? | PubMed ID: 17629792 | Fulltext

Platelet and leukocyte activation, atherosclerosis and inflammation in European and South Asian men.

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Dotsenko O, Chaturvedi N, Thom SA, Wright AR, Mayet J, Shore A, Schalkwijk C, and Hughes AD

Journal of thrombosis and haemostasis : JTH 5(10):2036-42, 2007 Oct - Who cited this? | PubMed ID: 17883700 | Fulltext

Src family tyrosine kinases mediate contraction of rat isolated tail arteries in response to a hyposmotic stimulus.

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Wijetunge S and Hughes AD

Journal of hypertension 25(9):1871-8, 2007 Sep - Who cited this? | PubMed ID: 17762651 | Fulltext

Analysis of complex flow and the relationship between blood pressure, wall shear stress, and intima-media thickness in the human carotid artery.

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Augst AD, Ariff B, McG Thom SA, Xu XY, and Hughes AD

American journal of physiology. Heart and circulatory physiology 293(2):H1031-7, 2007 Aug - Who cited this? | PubMed ID: 17449549 | Fulltext

Indian Asian men have less peripheral arterial disease than European men for equivalent levels of coronary disease.

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Chaturvedi N, Coady E, Mayet J, Wright AR, Shore AC, Byrd S, McG Thom SA, Kooner JS, Schalkwijk CG, and Hughes AD

Atherosclerosis 193(1):204-12, 2007 Jul - Who cited this? | PubMed ID: 16860806 | Fulltext

Drug effects on the mechanical properties of large arteries in humans.

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Hope SA and Hughes AD

Clinical and experimental pharmacology & physiology 34(7):688-93, 2007 Jul - Who cited this? | PubMed ID: 17581231 | Fulltext

Reduced systolic wave generation and increased peripheral wave reflection in chronic heart failure.

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Curtis SL, Zambanini A, Mayet J, McG Thom SA, Foale R, Parker KH, and Hughes AD

American journal of physiology. Heart and circulatory physiology 293(1):H557-62, 2007 Jul - Who cited this? | PubMed ID: 17400718 | Fulltext

Role of MRI in investigating the effects of elastic compression stockings on the deformation of the superficial and deep veins in the lower leg.

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Downie SP, Firmin DN, Wood NB, Thom SA, Hughes AD, Wolfe JN, and Xu XY

Journal of magnetic resonance imaging : JMRI 26(1):80-5, 2007 Jul - Who cited this? | PubMed ID: 17659543 | Fulltext

Effects of transmural pressure and wall shear stress on LDL accumulation in the arterial wall: a numerical study using a multilayered model.

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Sun N, Wood NB, Hughes AD, Thom SA, and Yun Xu X

American journal of physiology. Heart and circulatory physiology 292(6):H3148-57, 2007 Jun - Who cited this? | PubMed ID: 17277019 | Fulltext

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