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Papers authored by Hruz PW

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Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice.

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Tu P, Bhasin S, Hruz PW, Herbst KL, Castellani LW, Hua N, Hamilton JA, and Guo W

Diabetes 58(8):1739-48, 2009 Aug - Who cited this? | PubMed ID: 19509018 | Fulltext

The Role of Protease Inhibitors in the Pathogenesis of HIV-Associated Lipodystrophy: Cellular Mechanisms and Clinical Implications.

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Flint OP, Noor MA, Hruz PW, Hylemon PB, Yarasheski K, Kotler DP, Parker RA, and Bellamine A

Toxicologic pathology 37(1):65-77, 2009 - Who cited this? | PubMed ID: 19171928 | Fulltext

HIV protease inhibitors and insulin resistance: lessons from in-vitro, rodent and healthy human volunteer models.

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Hruz PW

Current opinion in HIV and AIDS 3(6):660-5, 2008 Nov - Who cited this? | PubMed ID: 19373039 | Fulltext

HIV protease inhibitors that block GLUT4 precipitate acute, decompensated heart failure in a mouse model of dilated cardiomyopathy.

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Hruz PW, Yan Q, Struthers H, and Jay PY

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22(7):2161-7, 2008 Jul - Who cited this? | PubMed ID: 18256305 | Fulltext

Tipranavir without ritonavir does not acutely induce peripheral insulin resistance in a rodent model.

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Hruz PW and Yan Q

Journal of acquired immune deficiency syndromes (1999) 43(5):624-5, 2006 Dec 15 - Who cited this? | PubMed ID: 17133213 | Fulltext

Rosiglitazone inhibits mouse liver regeneration.

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Turmelle YP, Shikapwashya O, Tu S, Hruz PW, Yan Q, and Rudnick DA

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20(14):2609, 2006 Dec - Who cited this? | PubMed ID: 17077279 | Fulltext

Direct comparison of the acute in vivo effects of HIV protease inhibitors on peripheral glucose disposal.

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Yan Q and Hruz PW

Journal of acquired immune deficiency syndromes (1999) 40(4):398, 2005 Dec 1 - Who cited this? | PubMed ID: 16280693 | Fulltext

A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity.

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Hertel J, Struthers H, Horj CB, and Hruz PW

The Journal of biological chemistry 279(53):55147-52, 2004 Dec 31 - Who cited this? | PubMed ID: 15496402 | Fulltext

Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice.

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Shteyer E, Liao Y, Muglia LJ, Hruz PW, and Rudnick DA

Hepatology (Baltimore, Md.) 40(6):1322-32, 2004 Dec - Who cited this? | PubMed ID: 15565660 | Fulltext

Delayed hepatocellular mitotic progression and impaired liver regeneration in early growth response-1-deficient mice.

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Liao Y, Shikapwashya ON, Shteyer E, Dieckgraefe BK, Hruz PW, and Rudnick DA

The Journal of biological chemistry 279(41):43107-16, 2004 Oct 8 - Who cited this? | PubMed ID: 15265859 | Fulltext

HIV protease inhibitors acutely impair glucose-stimulated insulin release.

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Koster JC, Remedi MS, Qiu H, Nichols CG, and Hruz PW

Diabetes 52(7):1695-700, 2003 Jul - Who cited this? | PubMed ID: 12829635 | Fulltext

Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations.

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Murata H, Hruz PW, and Mueckler M

AIDS (London, England) 16(6):859-63, 2002 Apr 12 - Who cited this? | PubMed ID: 11919487 | Fulltext

Indinavir induces acute and reversible peripheral insulin resistance in rats.

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Hruz PW, Murata H, Qiu H, and Mueckler M

Diabetes 51(4):937-42, 2002 Apr - Who cited this? | PubMed ID: 11916910 | Fulltext

Investigating the cellular targets of HIV protease inhibitors: implications for metabolic disorders and improvements in drug therapy.

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Murata H, Hruz PW, and Mueckler M

Current drug targets. Infectious disorders 2(1):1-8, 2002 Mar - Who cited this? | PubMed ID: 12462148 | Fulltext

Adverse metabolic consequences of HIV protease inhibitor therapy: the search for a central mechanism.

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Hruz PW, Murata H, and Mueckler M

American journal of physiology. Endocrinology and metabolism 280(4):E549-53, 2001 Apr - Who cited this? | PubMed ID: 11254460 | Fulltext

Structural analysis of the GLUT1 facilitative glucose transporter (review).

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Hruz PW and Mueckler MM

Molecular membrane biology 18(3):183-93, 2001 - Who cited this? | PubMed ID: 11681785 | Fulltext

Cysteine-scanning mutagenesis of transmembrane segment 11 of the GLUT1 facilitative glucose transporter.

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Hruz PW and Mueckler MM

Biochemistry 39(31):9367-72, 2000 Aug 8 - Who cited this? | PubMed ID: 10924131 | Fulltext

The mechanism of insulin resistance caused by HIV protease inhibitor therapy.

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Murata H, Hruz PW, and Mueckler M

The Journal of biological chemistry 275(27):20251-4, 2000 Jul 7 - Who cited this? | PubMed ID: 10806189 | Fulltext

Cysteine-scanning mutagenesis of transmembrane segment 7 of the GLUT1 glucose transporter.

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Hruz PW and Mueckler MM

The Journal of biological chemistry 274(51):36176-80, 1999 Dec 17 - Who cited this? | PubMed ID: 10593902 | Fulltext

3-Hydroxy-3-methylglutaryl-CoA lyase: expression and isolation of the recombinant human enzyme and investigation of a mechanism for regulation of enzyme activity.

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Roberts JR, Narasimhan C, Hruz PW, Mitchell GA, and Miziorko HM

The Journal of biological chemistry 269(27):17841-6, 1994 Jul 8 - Who cited this? | PubMed ID: 8027038 | Fulltext

3-Hydroxy-3-methylglutaryldithio-CoA: utility of an alternative substrate in elucidation of a role for HMG-CoA lyase's cation activator.

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Hruz PW, Anderson VE, and Miziorko HM

Biochimica et biophysica acta 1162(1-2):149-54, 1993 Mar 5 - Who cited this? | PubMed ID: 8095409 | Fulltext

3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL). Cloning of human and chicken liver HL cDNAs and characterization of a mutation causing human HL deficiency.

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Mitchell GA, Robert MF, Hruz PW, Wang S, Fontaine G, Behnke CE, Mende-Mueller LM, Schappert K, Lee C, and Gibson KM

The Journal of biological chemistry 268(6):4376-81, 1993 Feb 25 - Who cited this? | PubMed ID: 8440722 | Fulltext

Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines.

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Hruz PW and Miziorko HM

Protein science : a publication of the Protein Society 1(9):1144-53, 1992 Sep - Who cited this? | PubMed ID: 1304393 | Fulltext

3-Hydroxy-3-methylglutaryl coenzyme A lyase: affinity labeling of the Pseudomonas mevalonii enzyme and assignment of cysteine-237 to the active site.

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Hruz PW, Narasimhan C, and Miziorko HM

Biochemistry 31(29):6842-7, 1992 Jul 28 - Who cited this? | PubMed ID: 1637819 | Fulltext

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