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Papers authored by Hruz P

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Changes in mRNA expression levels of solute carrier transporters in inflammatory bowel disease patients.

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Wojtal KA, Eloranta JJ, Hruz P, Gutmann H, Drewe J, Staumann A, Beglinger C, Fried M, Kullak-Ublick GA, and Vavricka SR

Drug metabolism and disposition: the biological fate of chemicals 37(9):1871-7, 2009 Sep - Who cited this? | PubMed ID: 19487253 | Fulltext

CXCR2-dependent mucosal neutrophil influx protects against colitis-associated diarrhea caused by an attaching/effacing lesion-forming bacterial pathogen.

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Spehlmann ME, Dann SM, Hruz P, Hanson E, McCole DF, and Eckmann L

Journal of immunology (Baltimore, Md. : 1950) 183(5):3332-43, 2009 Sep 1 - Who cited this? | PubMed ID: 19675161 | Fulltext

NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation.

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Hruz P, Zinkernagel AS, Jenikova G, Botwin GJ, Hugot JP, Karin M, Nizet V, and Eckmann L

Proceedings of the National Academy of Sciences of the United States of America 106(31):12873-8, 2009 Aug 4 - Who cited this? | PubMed ID: 19541630 | Fulltext

Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice.

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Tu P, Bhasin S, Hruz PW, Herbst KL, Castellani LW, Hua N, Hamilton JA, and Guo W

Diabetes 58(8):1739-48, 2009 Aug - Who cited this? | PubMed ID: 19509018 | Fulltext

Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia.

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Valdez CA, Tripp JC, Miyamoto Y, Kalisiak J, Hruz P, Andersen YS, Brown SE, Kangas K, Arzu LV, Davids BJ, Gillin FD, Upcroft JA, Upcroft P, Fokin VV, Smith DK, Sharpless KB,

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Journal of medicinal chemistry 52(13):4038-53, 2009 Jul 9 - Who cited this? | PubMed ID: 19480409 | Fulltext

What's new in the diagnosis and therapy of eosinophilic esophagitis?.

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Straumann A and Hruz P

Current opinion in gastroenterology 25(4):366-71, 2009 Jul - Who cited this? | PubMed ID: 19444097 | Fulltext

The Role of Protease Inhibitors in the Pathogenesis of HIV-Associated Lipodystrophy: Cellular Mechanisms and Clinical Implications.

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Flint OP, Noor MA, Hruz PW, Hylemon PB, Yarasheski K, Kotler DP, Parker RA, and Bellamine A

Toxicologic pathology 37(1):65-77, 2009 - Who cited this? | PubMed ID: 19171928 | Fulltext

HIV protease inhibitors and insulin resistance: lessons from in-vitro, rodent and healthy human volunteer models.

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Hruz PW

Current opinion in HIV and AIDS 3(6):660-5, 2008 Nov - Who cited this? | PubMed ID: 19373039 | Fulltext

Contribution of metabolic and anthropometric abnormalities to cardiovascular disease risk factors.

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Grunfeld C, Kotler DP, Arnett DK, Falutz JM, Haffner SM, Hruz P, Masur H, Meigs JB, Mulligan K, Reiss P, Samaras K, and for Working Group 1

Circulation 118(2):e20-8, 2008 Jul 8 - Who cited this? | PubMed ID: 18566314 | Fulltext

Identification of brain structures involved in micturition with functional magnetic resonance imaging (fMRI).

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Hruz P, Lövblad KO, Nirkko AC, Thoeny H, El-Koussy M, and Danuser H

Journal of neuroradiology. Journal de neuroradiologie 35(3):144, 2008 Jul - Who cited this? | PubMed ID: 18243317 | Fulltext

HIV protease inhibitors that block GLUT4 precipitate acute, decompensated heart failure in a mouse model of dilated cardiomyopathy.

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Hruz PW, Yan Q, Struthers H, and Jay PY

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22(7):2161-7, 2008 Jul - Who cited this? | PubMed ID: 18256305 | Fulltext

Caspase recruitment domain-containing sensors and adaptors in intestinal innate immunity.

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Hruz P and Eckmann L

Current opinion in gastroenterology 24(2):108-14, 2008 Mar - Who cited this? | PubMed ID: 18301258 | Fulltext

Breast cancer resistance protein and P-glycoprotein expression in patients with newly diagnosed and therapy-refractory ulcerative colitis compared with healthy controls.

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Gutmann H, Hruz P, Zimmermann C, Straumann A, Terracciano L, Hammann F, Lehmann F, Beglinger C, and Drewe J

Digestion 78(2-3):154-62, 2008 - Who cited this? | PubMed ID: 19052456 | Fulltext

[Enuresis in therapy with psychotropic drugs].

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Zahno A, Ramseier E, and Hruz P

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis 96(36):1357-8, 2007 Sep 5 - Who cited this? | PubMed ID: 17894120 | Fulltext

[Urticaria after subcutaneous administration of Insulatard].

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Hruz P, Stöckli R, and Bircher A

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis 96(19):781-2, 2007 May 9 - Who cited this? | PubMed ID: 17571635 | Fulltext

Tipranavir without ritonavir does not acutely induce peripheral insulin resistance in a rodent model.

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Hruz PW and Yan Q

Journal of acquired immune deficiency syndromes (1999) 43(5):624-5, 2006 Dec 15 - Who cited this? | PubMed ID: 17133213 | Fulltext

Rosiglitazone inhibits mouse liver regeneration.

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Turmelle YP, Shikapwashya O, Tu S, Hruz PW, Yan Q, and Rudnick DA

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20(14):2609, 2006 Dec - Who cited this? | PubMed ID: 17077279 | Fulltext

Adaptive regulation of the ileal apical sodium dependent bile acid transporter (ASBT) in patients with obstructive cholestasis.

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Hruz P, Zimmermann C, Gutmann H, Degen L, Beuers U, Terracciano L, Drewe J, and Beglinger C

Gut 55(3):395-402, 2006 Mar - Who cited this? | PubMed ID: 16150853 | Fulltext

Glucagon-like peptide-1 is involved in sodium and water homeostasis in humans.

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Gutzwiller JP, Hruz P, Huber AR, Hamel C, Zehnder C, Drewe J, Gutmann H, Stanga Z, Vogel D, and Beglinger C

Digestion 73(2-3):142-50, 2006 - Who cited this? | PubMed ID: 16809911 | Fulltext

Decreased expression of breast cancer resistance protein in the duodenum in patients with obstructive cholestasis.

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Zimmermann C, Hruz P, Gutmann H, Terracciano L, Beuers U, Lehmann F, Beglinger C, and Drewe J

Digestion 74(2):101-8, 2006 - Who cited this? | PubMed ID: 17159348 | Fulltext

Direct comparison of the acute in vivo effects of HIV protease inhibitors on peripheral glucose disposal.

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Yan Q and Hruz PW

Journal of acquired immune deficiency syndromes (1999) 40(4):398, 2005 Dec 1 - Who cited this? | PubMed ID: 16280693 | Fulltext

[Foot drop paralysis after intoxicated state].

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Hruz P and Zeller A

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis 94(46):1823-4, 2005 Nov 16 - Who cited this? | PubMed ID: 16329405 | Fulltext

Distribution of breast cancer resistance protein (BCRP/ABCG2) mRNA expression along the human GI tract.

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Gutmann H, Hruz P, Zimmermann C, Beglinger C, and Drewe J

Biochemical pharmacology 70(5):695-9, 2005 Sep 1 - Who cited this? | PubMed ID: 15998509 | Fulltext

[A small virus among the large].

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Hruz P, Hirsch HH, and Zeller A

Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis 94(19):785-7, 2005 May 11 - Who cited this? | PubMed ID: 15940912 | Fulltext

Mapping of multidrug resistance gene 1 and multidrug resistance-associated protein isoform 1 to 5 mRNA expression along the human intestinal tract.

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Zimmermann C, Gutmann H, Hruz P, Gutzwiller JP, Beglinger C, and Drewe J

Drug metabolism and disposition: the biological fate of chemicals 33(2):219-24, 2005 Feb - Who cited this? | PubMed ID: 15523049 | Fulltext

A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity.

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Hertel J, Struthers H, Horj CB, and Hruz PW

The Journal of biological chemistry 279(53):55147-52, 2004 Dec 31 - Who cited this? | PubMed ID: 15496402 | Fulltext

Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice.

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Shteyer E, Liao Y, Muglia LJ, Hruz PW, and Rudnick DA

Hepatology (Baltimore, Md.) 40(6):1322-32, 2004 Dec - Who cited this? | PubMed ID: 15565660 | Fulltext

Delayed hepatocellular mitotic progression and impaired liver regeneration in early growth response-1-deficient mice.

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Liao Y, Shikapwashya ON, Shteyer E, Dieckgraefe BK, Hruz PW, and Rudnick DA

The Journal of biological chemistry 279(41):43107-16, 2004 Oct 8 - Who cited this? | PubMed ID: 15265859 | Fulltext

Non-inflammatory chronic pelvic pain syndrome can be caused by bladder neck hypertrophy.

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Hruz P, Danuser H, Studer UE, and Hochreiter WW

European urology 44(1):106-10; discussion 110, 2003 Jul - Who cited this? | PubMed ID: 12814683 | Fulltext

HIV protease inhibitors acutely impair glucose-stimulated insulin release.

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Koster JC, Remedi MS, Qiu H, Nichols CG, and Hruz PW

Diabetes 52(7):1695-700, 2003 Jul - Who cited this? | PubMed ID: 12829635 | Fulltext

[Evaluation of symptoms in men with chronic pelvic pain].

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Hochreiter WW, Hruz P, Danuser H, Weidner W, and Studer UE

Der Urologe. Ausg. A 42(1):38-40, 2003 Jan - Who cited this? | PubMed ID: 12574882 | Fulltext

Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations.

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Murata H, Hruz PW, and Mueckler M

AIDS (London, England) 16(6):859-63, 2002 Apr 12 - Who cited this? | PubMed ID: 11919487 | Fulltext

Indinavir induces acute and reversible peripheral insulin resistance in rats.

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Hruz PW, Murata H, Qiu H, and Mueckler M

Diabetes 51(4):937-42, 2002 Apr - Who cited this? | PubMed ID: 11916910 | Fulltext

Fanconi's syndrome, acute renal failure, and tonsil ulcerations after colloidal bismuth subcitrate intoxication.

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Hruz P, Mayr M, Löw R, Drewe J, and Huber G

American journal of kidney diseases : the official journal of the National Kidney Foundation 39(3):E18, 2002 Mar - Who cited this? | PubMed ID: 11877598 | Fulltext

Investigating the cellular targets of HIV protease inhibitors: implications for metabolic disorders and improvements in drug therapy.

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Murata H, Hruz PW, and Mueckler M

Current drug targets. Infectious disorders 2(1):1-8, 2002 Mar - Who cited this? | PubMed ID: 12462148 | Fulltext

Intranasal administration of delta sleep-inducing peptide increases P300.

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Hruz P, Zechner S, Heimberg D, Hobi V, Schönenberger GA, Scheffler K, Müller-Spahn F, and Seifritz E

Journal of clinical psychopharmacology 21(6):626-8, 2001 Dec - Who cited this? | PubMed ID: 11763019 | Fulltext

Adverse metabolic consequences of HIV protease inhibitor therapy: the search for a central mechanism.

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Hruz PW, Murata H, and Mueckler M

American journal of physiology. Endocrinology and metabolism 280(4):E549-53, 2001 Apr - Who cited this? | PubMed ID: 11254460 | Fulltext

Structural analysis of the GLUT1 facilitative glucose transporter (review).

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Hruz PW and Mueckler MM

Molecular membrane biology 18(3):183-93, 2001 - Who cited this? | PubMed ID: 11681785 | Fulltext

Cysteine-scanning mutagenesis of transmembrane segment 11 of the GLUT1 facilitative glucose transporter.

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Hruz PW and Mueckler MM

Biochemistry 39(31):9367-72, 2000 Aug 8 - Who cited this? | PubMed ID: 10924131 | Fulltext

The mechanism of insulin resistance caused by HIV protease inhibitor therapy.

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Murata H, Hruz PW, and Mueckler M

The Journal of biological chemistry 275(27):20251-4, 2000 Jul 7 - Who cited this? | PubMed ID: 10806189 | Fulltext

Cysteine-scanning mutagenesis of transmembrane segment 7 of the GLUT1 glucose transporter.

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Hruz PW and Mueckler MM

The Journal of biological chemistry 274(51):36176-80, 1999 Dec 17 - Who cited this? | PubMed ID: 10593902 | Fulltext

3-Hydroxy-3-methylglutaryl-CoA lyase: expression and isolation of the recombinant human enzyme and investigation of a mechanism for regulation of enzyme activity.

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Roberts JR, Narasimhan C, Hruz PW, Mitchell GA, and Miziorko HM

The Journal of biological chemistry 269(27):17841-6, 1994 Jul 8 - Who cited this? | PubMed ID: 8027038 | Fulltext

3-Hydroxy-3-methylglutaryldithio-CoA: utility of an alternative substrate in elucidation of a role for HMG-CoA lyase's cation activator.

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Hruz PW, Anderson VE, and Miziorko HM

Biochimica et biophysica acta 1162(1-2):149-54, 1993 Mar 5 - Who cited this? | PubMed ID: 8095409 | Fulltext

3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL). Cloning of human and chicken liver HL cDNAs and characterization of a mutation causing human HL deficiency.

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Mitchell GA, Robert MF, Hruz PW, Wang S, Fontaine G, Behnke CE, Mende-Mueller LM, Schappert K, Lee C, and Gibson KM

The Journal of biological chemistry 268(6):4376-81, 1993 Feb 25 - Who cited this? | PubMed ID: 8440722 | Fulltext

3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL): cloning and characterization of a mouse liver HL cDNA and subchromosomal mapping of the human and mouse HL genes.

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Wang S, Nadeau JH, Duncan A, Robert MF, Fontaine G, Schappert K, Johnson KR, Zietkiewicz E, Hruz P, and Miziorko H

Mammalian genome : official journal of the International Mammalian Genome Society 4(7):382-7, 1993 - Who cited this? | PubMed ID: 8102917 | Fulltext

Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines.

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Hruz PW and Miziorko HM

Protein science : a publication of the Protein Society 1(9):1144-53, 1992 Sep - Who cited this? | PubMed ID: 1304393 | Fulltext

3-Hydroxy-3-methylglutaryl coenzyme A lyase: affinity labeling of the Pseudomonas mevalonii enzyme and assignment of cysteine-237 to the active site.

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Hruz PW, Narasimhan C, and Miziorko HM

Biochemistry 31(29):6842-7, 1992 Jul 28 - Who cited this? | PubMed ID: 1637819 | Fulltext

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