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Papers authored by Hotchandani R

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Identification of an orally efficacious matrix metalloprotease 12 inhibitor for potential treatment of asthma.

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Li W, Li J, Wu Y, Rancati F, Vallese S, Raveglia L, Wu J, Hotchandani R, Fuller N, Cunningham K, Morgan P, Fish S, Krykbaev R, Xu X, Tam S, Goldman SJ,

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Journal of medicinal chemistry 52(17):5408-19, 2009 Sep 10 - Who cited this? | PubMed ID: 19725580 | Fulltext

3,4-Disubstituted benzofuran P1' MMP-13 inhibitors: optimization of selectivity and reduction of protein binding.

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Li W, Hu Y, Li J, Thomason JR, DeVincentis D, Du X, Wu J, Hotchandani R, Rush TS, Skotnicki JS, Tam S, Chockalingam PS, Morris EA, and Levin JI

Bioorganic & medicinal chemistry letters 19(16):4546-50, 2009 Aug 15 - Who cited this? | PubMed ID: 19625186 | Fulltext

Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-alpha production in human whole blood.

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Wu J, Green N, Hotchandani R, Hu Y, Condon J, Huang A, Kaila N, Li HQ, Guler S, Li W, Tam SY, Wang Q, Pelker J, Marusic S, Hsu S, Perry Hall J,

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Bioorganic & medicinal chemistry letters 19(13):3485-8, 2009 Jul 1 - Who cited this? | PubMed ID: 19464884 | Fulltext

A Selective Matrix Metalloprotease 12 Inhibitor for Potential Treatment of Chronic Obstructive Pulmonary Disease (COPD): Discovery of (S)-2-(8-(Methoxycarbonylamino)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid (MMP408).

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Li W, Li J, Wu Y, Wu J, Hotchandani R, Cunningham K, McFadyen I, Bard J, Morgan P, Schlerman F, Xu X, Tam S, Goldman SJ, Williams C, Sypek J, and Mansour TS

Journal of medicinal chemistry 52(7):1799-802, 2009 Apr 9 - Who cited this? | PubMed ID: 19278250 | Fulltext

Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24.

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Wan ZK, Lee J, Hotchandani R, Moretto A, Binnun E, Wilson DP, Kirincich SJ, Follows BC, Ipek M, Xu W, Joseph-McCarthy D, Zhang YL, Tam M, Erbe DV, Tobin JF, Li W,

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ChemMedChem 3(10):1525-9, 2008 Oct - Who cited this? | PubMed ID: 18798205 | Fulltext

Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor alpha (TNF-alpha) production: selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3-carbonitriles.

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Green N, Hu Y, Janz K, Li HQ, Kaila N, Guler S, Thomason J, Joseph-McCarthy D, Tam SY, Hotchandani R, Wu J, Huang A, Wang Q, Leung L, Pelker J, Marusic S,

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Journal of medicinal chemistry 50(19):4728-45, 2007 Sep 20 - Who cited this? | PubMed ID: 17715908 | Fulltext

Identification of potent and selective MMP-13 inhibitors.

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Wu J, Rush TS, Hotchandani R, Du X, Geck M, Collins E, Xu ZB, Skotnicki J, Levin JI, and Lovering FE

Bioorganic & medicinal chemistry letters 15(18):4105-9, 2005 Sep 15 - Who cited this? | PubMed ID: 16005220 | Fulltext

Situs inversus: a rare extrarenal association of Alport's syndrome.

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Mittal R, Saxena S, Hotchandani RK, Agarwal SK, Tiwari SC, and Dash SC

Nephron 68(3):390, 1994 - Who cited this? | PubMed ID: 7838269 | Fulltext

Bilateral renal stones associated with nail-patella syndrome.

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Mittal R, Saxena S, Hotchandani RK, Agarwal SK, Tiwari SC, and Dash SC

Nephron 68(4):509, 1994 - Who cited this? | PubMed ID: 7870239 | Fulltext

Membranous glomerulonephritis associated with autosomal dominant polycystic kidney disease.

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Saxena S, Hotchandani RK, Bhuyan UN, Agarwal SK, Tiwari SC, and Dash SC

Nephron 65(2):316-7, 1993 - Who cited this? | PubMed ID: 8247200 | Fulltext

Reduced incidence of left ventricular thrombi with intravenous streptokinase in acute anterior myocardial infarction: prospective evaluation by cross-sectional echocardiography.

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Natarajan D, Hotchandani RK, and Nigam PD

International journal of cardiology 20(2):201-7, 1988 Aug - Who cited this? | PubMed ID: 3209251 | Fulltext

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