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Papers authored by Holt PR

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Western-style diets induce oxidative stress and dysregulate immune responses in the colon in a mouse model of sporadic colon cancer.

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Erdelyi I, Levenkova N, Lin EY, Pinto JT, Lipkin M, Quimby FW, and Holt PR

The Journal of nutrition 139(11):2072-8, 2009 Nov - Who cited this? | PubMed ID: 19759248 | Fulltext

Chemoprevention of colorectal neoplasia by estrogen: potential role of vitamin D activity.

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Protiva P, Cross HS, Hopkins ME, Kállay E, Bises G, Dreyhaupt E, Augenlicht L, Lipkin M, Lesser M, Livote E, and Holt PR

Cancer prevention research (Philadelphia, Pa.) 2(1):43-51, 2009 Jan - Who cited this? | PubMed ID: 19139017 | Fulltext

Colon cancer and the elderly: From screening to treatment in management of GI disease in the elderly.

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Holt PR, Kozuch P, and Mewar S

Best practice & research. Clinical gastroenterology 23(6):889-907, 2009 - Who cited this? | PubMed ID: 19942166 | Fulltext

Chemoprevention of colorectal neoplasia.

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Holick MF and Holt PR

Gastroenterology 135(4):1427-8, 2008 Oct - Who cited this? | PubMed ID: 18789938 | Fulltext

Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response.

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Protiva P, Hopkins ME, Baggett S, Yang H, Lipkin M, Holt PR, Kennelly EJ, and Bernard WI

International journal of cancer. Journal international du cancer 123(3):687, 2008 Aug 1 - Who cited this? | PubMed ID: 18470880 | Fulltext

New insights into calcium, dairy and colon cancer.

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Holt PR

World journal of gastroenterology : WJG 14(28):4429, 2008 Jul 28 - Who cited this? | PubMed ID: 18680219 | Fulltext

Re: Severe toxic hepatitis.

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Pinillos H, Holt PR, and Thung S

Digestive diseases and sciences 52(9):2460-1, 2007 Sep - Who cited this? | PubMed ID: 17415657 | Fulltext

Intestinal malabsorption in the elderly.

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Holt PR

Digestive diseases (Basel, Switzerland) 25(2):144-50, 2007 - Who cited this? | PubMed ID: 17468550 | Fulltext

Soy isoflavone intake and estrogen excretion patterns in young women: effect of probiotic administration.

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Cohen LA, Crespin JS, Wolper C, Zang EA, Pittman B, Zhao Z, and Holt PR

In vivo (Athens, Greece) 21(3):507-12, 2007 - Who cited this? | PubMed ID: 17591361 | Fulltext

Non-steroidal anti-inflammatory drugs have bacteriostatic and bactericidal activity against Helicobacter pylori.

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Shirin H, Moss SF, Kancherla S, Kancherla K, Holt PR, Weinstein IB, and Sordillo EM

Journal of gastroenterology and hepatology 21(9):1388-93, 2006 Sep - Who cited this? | PubMed ID: 16911681 | Fulltext

Effects of aging of the population.

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Holt PR

Gastroenterology 130(4):1371; author reply 1371-2, 2006 Apr - Who cited this? | PubMed ID: 16618435 | Fulltext

Calcium plus vitamin D alters preneoplastic features of colorectal adenomas and rectal mucosa.

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Holt PR, Bresalier RS, Ma CK, Liu KF, Lipkin M, Byrd JC, and Yang K

Cancer 106(2):287-96, 2006 Jan 15 - Who cited this? | PubMed ID: 16353199 | Fulltext

Curcumin therapy in inflammatory bowel disease: a pilot study.

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Holt PR, Katz S, and Kirshoff R

Digestive diseases and sciences 50(11):2191-3, 2005 Nov - Who cited this? | PubMed ID: 16240238 | Fulltext

Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells.

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Agarwal B, Swaroop P, Protiva P, Raj SV, Shirin H, and Holt PR

Apoptosis : an international journal on programmed cell death 8(6):649-54, 2003 Dec - Who cited this? | PubMed ID: 14739610 | Fulltext

Gastrointestinal diseases in the elderly.

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Holt PR

Current opinion in clinical nutrition and metabolic care 6(1):41-8, 2003 Jan - Who cited this? | PubMed ID: 12496679 | Fulltext

Colorectal cancer prevention: prospects for the first decade of the 21st century.

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Holt PR

Preventive medicine 34(6):563-6, 2002 Jun - Who cited this? | PubMed ID: 12052014 | Fulltext

Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells.

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Agarwal B, Halmos B, Feoktistov AS, Protiva P, Ramey WG, Chen M, Pothoulakis C, Lamont JT, and Holt PR

Carcinogenesis 23(3):521-8, 2002 Mar - Who cited this? | PubMed ID: 11895868 | Fulltext

Colonic epithelial cell proliferation decreases with increasing levels of serum 25-hydroxy vitamin D.

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Holt PR, Arber N, Halmos B, Forde K, Kissileff H, McGlynn KA, Moss SF, Kurihara N, Fan K, Yang K, and Lipkin M

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 11(1):113-9, 2002 Jan - Who cited this? | PubMed ID: 11815408 | Fulltext

p21(WAF1/cip1) is an important determinant of intestinal cell response to sulindac in vitro and in vivo.

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Yang W, Velcich A, Mariadason J, Nicholas C, Corner G, Houston M, Edelmann W, Kucherlapati R, Holt PR, and Augenlicht LH

Cancer research 61(16):6297-302, 2001 Aug 15 - Who cited this? | PubMed ID: 11507085 | Fulltext

Diarrhea and malabsorption in the elderly.

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Holt PR

Gastroenterology clinics of North America 30(2):427-44, 2001 Jun - Who cited this? | PubMed ID: 11432299 | Fulltext

25-hydroxyvitamin D-1alpha-hydroxylase in normal and malignant colon tissue.

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Tangpricha V, Flanagan JN, Whitlatch LW, Tseng CC, Chen TC, Holt PR, Lipkin MS, and Holick MF

Lancet 357(9269):1673-4, 2001 May 26 - Who cited this? | PubMed ID: 11425375 | Fulltext

Increased gastric epithelial cell apoptosis associated with colonization with cagA + Helicobacter pylori strains.

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Moss SF, Sordillo EM, Abdalla AM, Makarov V, Hanzely Z, Perez-Perez GI, Blaser MJ, and Holt PR

Cancer research 61(4):1406-11, 2001 Feb 15 - Who cited this? | PubMed ID: 11245442 | Fulltext

Antiproliferative effects of S-allylmercaptocysteine on colon cancer cells when tested alone or in combination with sulindac sulfide.

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Shirin H, Pinto JT, Kawabata Y, Soh JW, Delohery T, Moss SF, Murty V, Rivlin RS, Holt PR, and Weinstein IB

Cancer research 61(2):725-31, 2001 Jan 15 - Who cited this? | PubMed ID: 11212275 | Fulltext

Comparison of calcium supplementation or low-fat dairy foods on epithelial cell proliferation and differentiation.

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Holt PR, Wolper C, Moss SF, Yang K, and Lipkin M

Nutrition and cancer 41(1-2):150-5, 2001 - Who cited this? | PubMed ID: 12094618 | Fulltext

Peptic disease in elderly patients.

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Khaghan N and Holt PR

Canadian journal of gastroenterology = Journal canadien de gastroenterologie 14(11):922-8, 2000 Dec - Who cited this? | PubMed ID: 11125182 | Fulltext

Ziprasidone and the pharmacokinetics of a combined oral contraceptive.

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Muirhead GJ, Harness J, Holt PR, Oliver S, and Anziano RJ

British journal of clinical pharmacology 49 Suppl 1:49S-56S, 2000 - Who cited this? | PubMed ID: 10771454 | Fulltext

Gastrin-mediated alterations in gastric epithelial apoptosis and proliferation in a mastomys rodent model of gastric neoplasia.

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Kidd M, Tang LH, Modlin IM, Zhang T, Chin K, Holt PR, and Moss SF

Digestion 62(2-3):143-51, 2000 - Who cited this? | PubMed ID: 11025361 | Fulltext

Abnormalities in the expression of cell cycle-related proteins in tumors of the small bowel.

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Arber N, Hibshoosh H, Yasui W, Neugut AI, Hibshoosh A, Yao Y, Sgambato A, Yamamoto H, Shapira I, Rosenman D, Fabian I, Weinstein IB, Tahara E, and Holt PR

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 8(12):1101-5, 1999 Dec - Who cited this? | PubMed ID: 10613343 | Fulltext

Decreased and aberrant nuclear lamin expression in gastrointestinal tract neoplasms.

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Moss SF, Krivosheyev V, de Souza A, Chin K, Gaetz HP, Chaudhary N, Worman HJ, and Holt PR

Gut 45(5):723-9, 1999 Nov - Who cited this? | PubMed ID: 10517909 | Fulltext

Role of thyroid hormone in stimulating liver repopulation in the rat by transplanted hepatocytes.

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Oren R, Dabeva MD, Karnezis AN, Petkov PM, Rosencrantz R, Sandhu JP, Moss SF, Wang S, Hurston E, Laconi E, Holt PR, Thung SN, Zhu L, and Shafritz DA

Hepatology (Baltimore, Md.) 30(4):903-13, 1999 Oct - Who cited this? | PubMed ID: 10498641 | Fulltext

Lovastatin augments sulindac-induced apoptosis in colon cancer cells and potentiates chemopreventive effects of sulindac.

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Agarwal B, Rao CV, Bhendwal S, Ramey WR, Shirin H, Reddy BS, and Holt PR

Gastroenterology 117(4):838-47, 1999 Oct - Who cited this? | PubMed ID: 10500066 | Fulltext

Dairy foods and prevention of colon cancer: human studies.

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Holt PR

Journal of the American College of Nutrition 18(5 Suppl):379S-391S, 1999 Oct - Who cited this? | PubMed ID: 10511318 | Fulltext

Overexpression of cyclin D1 occurs in both squamous carcinomas and adenocarcinomas of the esophagus and in adenocarcinomas of the stomach.

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Arber N, Gammon MD, Hibshoosh H, Britton JA, Zhang Y, Schonberg JB, Roterdam H, Fabian I, Holt PR, and Weinstein IB

Human pathology 30(9):1087-92, 1999 Sep - Who cited this? | PubMed ID: 10492044 | Fulltext

Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells.

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Agarwal B, Bhendwal S, Halmos B, Moss SF, Ramey WG, and Holt PR

Clinical cancer research : an official journal of the American Association for Cancer Research 5(8):2223-9, 1999 Aug - Who cited this? | PubMed ID: 10473109 | Fulltext

Human right and left colon differ in epithelial cell apoptosis and in expression of Bak, a pro-apoptotic Bcl-2 homologue.

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Liu LU, Holt PR, Krivosheyev V, and Moss SF

Gut 45(1):45-50, 1999 Jul - Who cited this? | PubMed ID: 10369703 | Fulltext

Association of K-ras mutations with p16 methylation in human colon cancer.

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Guan RJ, Fu Y, Holt PR, and Pardee AB

Gastroenterology 116(5):1063-71, 1999 May - Who cited this? | PubMed ID: 10220498 | Fulltext

Calcium intake and colon cancer biomarkers.

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Holt PR, Lipkin M, and Newmark H

JAMA : the journal of the American Medical Association 281(13):1172-3, 1999 Apr 7 - Who cited this? | PubMed ID: 10199422 | Fulltext

Studies of calcium in food supplements in humans.

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Holt PR

Annals of the New York Academy of Sciences 889:128-37, 1999 - Who cited this? | PubMed ID: 10668489 | Fulltext

Insensitivity of the CLOtest for H. pylori, especially in the elderly.

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Abdalla AM, Sordillo EM, Hanzely Z, Perez-Perez GI, Blaser MJ, Holt PR, and Moss SF

Gastroenterology 115(1):243-4, 1998 Jul - Who cited this? | PubMed ID: 9659344 | Fulltext

Dairy product-rich diets and cytotoxicity of fecal water.

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Newmark HL and Holt PR

The American journal of clinical nutrition 67(5):946-7, 1998 May - Who cited this? | PubMed ID: 9583855 | Fulltext

Diet restriction increases apoptosis in the gut of aging rats.

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Holt PR, Moss SF, Heydari AR, and Richardson A

The journals of gerontology. Series A, Biological sciences and medical sciences 53(3):B168-72, 1998 May - Who cited this? | PubMed ID: 9597039 | Fulltext

Amaranthin lectin binding in the rat colon: response to dietary manipulation.

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Atillasoy EO, Kapetanakis A, Itzkowitz SH, and Holt PR

The Mount Sinai journal of medicine, New York 65(2):146-53, 1998 Mar - Who cited this? | PubMed ID: 9520519 | Fulltext

Modulation of abnormal colonic epithelial cell proliferation and differentiation by low-fat dairy foods: a randomized controlled trial.

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Holt PR, Atillasoy EO, Gilman J, Guss J, Moss SF, Newmark H, Fan K, Yang K, and Lipkin M

JAMA : the journal of the American Medical Association 280(12):1074-9, 1998 - Who cited this? | PubMed ID: 9757855 | Fulltext

A K-ras oncogene increases resistance to sulindac-induced apoptosis in rat enterocytes.

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Arber N, Han EK, Sgambato A, Piazza GA, Delohery TM, Begemann M, Weghorst CM, Kim NH, Pamukcu R, Ahnen DJ, Reed JC, Weinstein IB, and Holt PR

Gastroenterology 113(6):1892-900, 1997 Dec - Who cited this? | PubMed ID: 9394728 | Fulltext

Apoptosis in gastric epithelial cells is induced by Helicobacter pylori and accompanied by increased expression of BAK.

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Chen G, Sordillo EM, Ramey WG, Reidy J, Holt PR, Krajewski S, Reed JC, Blaser MJ, and Moss SF

Biochemical and biophysical research communications 239(2):626-32, 1997 Oct 20 - Who cited this? | PubMed ID: 9344882 | Fulltext

Helicobacter pylori cagA+ strains and dissociation of gastric epithelial cell proliferation from apoptosis.

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Peek RM, Moss SF, Tham KT, Pérez-Pérez GI, Wang S, Miller GG, Atherton JC, Holt PR, and Blaser MJ

Journal of the National Cancer Institute 89(12):863-8, 1997 Jun 18 - Who cited this? | PubMed ID: 9196252 | Fulltext

Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells.

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Arber N, Doki Y, Han EK, Sgambato A, Zhou P, Kim NH, Delohery T, Klein MG, Holt PR, and Weinstein IB

Cancer research 57(8):1569-74, 1997 Apr 15 - Who cited this? | PubMed ID: 9108461 | Fulltext

Is Ki-67 a better proliferative marker in the colon than proliferating cell nuclear antigen?.

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Holt PR, Moss SF, Kapetanakis AM, Petrotos A, and Wang S

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 6(2):131-5, 1997 Feb - Who cited this? | PubMed ID: 9037564 | Fulltext

Are right- and left-sided colon neoplasms distinct tumors?.

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Distler P and Holt PR

Digestive diseases (Basel, Switzerland) 15(4-5):302-11, 1997 - Who cited this? | PubMed ID: 9359018 | Fulltext

Inward growth of colonic adenomatous polyps.

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Moss SF, Liu TC, Petrotos A, Hsu TM, Gold LI, and Holt PR

Gastroenterology 111(6):1425-32, 1996 Dec - Who cited this? | PubMed ID: 8942720 | Fulltext

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