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Papers authored by Hollingshead MG

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Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction.

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Stockwin LH, Han B, Yu SX, Hollingshead MG, Elsohly MA, Gul W, Slade D, Galal AM, and Newton DL

International journal of cancer. Journal international du cancer 125(6):1266-75, 2009 Sep 15 - Who cited this? | PubMed ID: 19533749 | Fulltext

Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity.

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Galal AM, Gul W, Slade D, Ross SA, Feng S, Hollingshead MG, Alley MC, Kaur G, and Elsohly MA

Bioorganic & medicinal chemistry 17(2):741-51, 2009 Jan 15 - Who cited this? | PubMed ID: 19084416 | Fulltext

ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC.

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Stockwin LH, Yu SX, Stotler H, Hollingshead MG, and Newton DL

BMC cancer 9:63, 2009 - Who cited this? | PubMed ID: 19232100 | Fulltext

Antitumor efficacy testing in rodents.

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Hollingshead MG

Journal of the National Cancer Institute 100(21):1500-10, 2008 Nov 5 - Who cited this? | PubMed ID: 18957675 | Fulltext

Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1.

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Wright MH, Robles AI, Herschkowitz JI, Hollingshead MG, Anver MR, Perou CM, and Varticovski L

Molecular cancer 7:29, 2008 - Who cited this? | PubMed ID: 18394172 | Fulltext

Advantage of combining NLCQ-1 (NSC 709257) with radiation in treatment of human head and neck xenografts.

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Papadopoulou MV, Bloomer WD, Taylor AP, Hernandez M, Blumenthal RD, and Hollingshead MG

Radiation research 168(1):65, 2007 Jul - Who cited this? | PubMed ID: 17722994 | Fulltext

Proteomic analysis identifies oxidative stress induction by adaphostin.

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Stockwin LH, Bumke MA, Yu SX, Webb SP, Collins JR, Hollingshead MG, and Newton DL

Clinical cancer research : an official journal of the American Association for Cancer Research 13(12):3667, 2007 Jun 15 - Who cited this? | PubMed ID: 17575232 | Fulltext

Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models.

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Varticovski L, Hollingshead MG, Robles AI, Wu X, Cherry J, Munroe DJ, Lukes L, Anver MR, Carter JP, Borgel SD, Stotler H, Bonomi CA, Nunez NP, Hursting SD, Qiao W, Deng CX,

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Clinical cancer research : an official journal of the American Association for Cancer Research 13(7):2168, 2007 Apr 1 - Who cited this? | PubMed ID: 17404101 | Fulltext

Inhibition of Akt by the alkylphospholipid perifosine does not enhance the radiosensitivity of human glioma cells.

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de la Peña L, Burgan WE, Carter DJ, Hollingshead MG, Satyamitra M, Camphausen K, and Tofilon PJ

Molecular cancer therapeutics 5(6):1504, 2006 Jun - Who cited this? | PubMed ID: 16818509 | Fulltext

In vitro and in vivo radiosensitization induced by the ribonucleotide reductase inhibitor Triapine (3-aminopyridine-2-carboxaldehyde-thiosemicarbazone).

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Barker CA, Burgan WE, Carter DJ, Cerna D, Gius D, Hollingshead MG, Camphausen K, and Tofilon PJ

Clinical cancer research : an official journal of the American Association for Cancer Research 12(9):2912, 2006 May 1 - Who cited this? | PubMed ID: 16675588 | Fulltext

NLCQ-1 (NSC 709257) in combination with radiation against human glioma U251 xenografts.

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Papadopoulou MV, Bloomer WD, and Hollingshead MG

Anticancer research 25(3B):1865 - Who cited this? | PubMed ID: 16158918 | Fulltext

A new synthetic agent with potent but selective cytotoxic activity against cancer.

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Cholody WM, Kosakowska-Cholody T, Hollingshead MG, Hariprakasha HK, and Michejda CJ

Journal of medicinal chemistry 48(13):4474-81, 2005 Jun 30 - Who cited this? | PubMed ID: 15974599 | Fulltext

Enhancement of in vitro and in vivo tumor cell radiosensitivity by the DNA methylation inhibitor zebularine.

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Dote H, Cerna D, Burgan WE, Carter DJ, Cerra MA, Hollingshead MG, Camphausen K, and Tofilon PJ

Clinical cancer research : an official journal of the American Association for Cancer Research 11(12):4571-9, 2005 Jun 15 - Who cited this? | PubMed ID: 15958643 | Fulltext

Synthesis, structure-activity relationship, and p210(bcr-abl) protein tyrosine kinase activity of novel AG 957 analogs.

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Kaur G, Narayanan VL, Risbood PA, Hollingshead MG, Stinson SF, Varma RK, and Sausville EA

Bioorganic & medicinal chemistry 13(5):1749-61, 2005 Mar 1 - Who cited this? | PubMed ID: 15698792 | Fulltext

Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin.

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Bull EE, Dote H, Brady KJ, Burgan WE, Carter DJ, Cerra MA, Oswald KA, Hollingshead MG, Camphausen K, and Tofilon PJ

Clinical cancer research : an official journal of the American Association for Cancer Research 10(23):8077-84, 2004 Dec 1 - Who cited this? | PubMed ID: 15585643 | Fulltext

SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity.

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Hartley JA, Spanswick VJ, Brooks N, Clingen PH, McHugh PJ, Hochhauser D, Pedley RB, Kelland LR, Alley MC, Schultz R, Hollingshead MG, Schweikart KM, Tomaszewski JE, Sausville EA, Gregson SJ, Howard PW,

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Cancer research 64(18):6693, 2004 Sep 15 - Who cited this? | PubMed ID: 15374986 | Fulltext

SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 2: efficacy evaluations.

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Alley MC, Hollingshead MG, Pacula-Cox CM, Waud WR, Hartley JA, Howard PW, Gregson SJ, Thurston DE, and Sausville EA

Cancer research 64(18):6700-6, 2004 Sep 15 - Who cited this? | PubMed ID: 15374987 | Fulltext

Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents.

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Adams BK, Ferstl EM, Davis MC, Herold M, Kurtkaya S, Camalier RF, Hollingshead MG, Kaur G, Sausville EA, Rickles FR, Snyder JP, Liotta DC, and Shoji M

Bioorganic & medicinal chemistry 12(14):3871-83, 2004 Jul 15 - Who cited this? | PubMed ID: 15210154 | Fulltext

A potential role for imaging technology in anticancer efficacy evaluations.

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Hollingshead MG, Bonomi CA, Borgel SD, Carter JP, Shoemaker R, Melillo G, and Sausville EA

European journal of cancer (Oxford, England : 1990) 40(6):890-8, 2004 Apr - Who cited this? | PubMed ID: 15120044 | Fulltext

"Vasocrine" formation of tumor cell-lined vascular spaces: implications for rational design of antiangiogenic therapies.

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Rybak SM, Sanovich E, Hollingshead MG, Borgel SD, Newton DL, Melillo G, Kong D, Kaur G, and Sausville EA

Cancer research 63(11):2812-9, 2003 Jun 1 - Who cited this? | PubMed ID: 12782586 | Fulltext

Therapeutic advantage from combining paclitaxel with the hypoxia-selective cytotoxin NLCQ-1 in murine tumor- or human xenograft-bearing mice.

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Papadopoulou MV, Ji M, Ji X, Bloomer WD, and Hollingshead MG

Cancer chemotherapy and pharmacology 50(6):501, 2002 Dec - Who cited this? | PubMed ID: 12451478 | Fulltext

Testing of new agents in childhood cancer preclinical models: meeting summary.

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Houghton PJ, Adamson PC, Blaney S, Fine HA, Gorlick R, Haber M, Helman L, Hirschfeld S, Hollingshead MG, Israel MA, Lock RB, Maris JM, Merlino G, Patterson W, Reynolds CP, Shannon K,

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Clinical cancer research : an official journal of the American Association for Cancer Research 8(12):3646-57, 2002 Dec - Who cited this? | PubMed ID: 12473573 | Fulltext

Enhancement of the antitumor effect of cyclophosphamide with the hypoxia-selective cytotoxin NLCQ-1 against murine tumors and human xenografts.

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Papadopoulou MV, Ji M, Bloomer WD, and Hollingshead MG

Journal of experimental therapeutics & oncology 2(5):298 - Who cited this? | PubMed ID: 12416033 | Fulltext

Pervilleines B and C, new tropane alkaloid aromatic esters that reverse the multidrug-resistance in the hollow fiber assay.

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Mi Q, Cui B, Silva GL, Lantvit D, Lim E, Chai H, Hollingshead MG, Mayo JG, Kinghorn AD, and Pezzuto JM

Cancer letters 184(1):13-20, 2002 Oct 8 - Who cited this? | PubMed ID: 12104043 | Fulltext

Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests.

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Mi Q, Lantvit D, Reyes-Lim E, Chai H, Zhao W, Lee IS, Peraza-Sánchez S, Ngassapa O, Kardono LB, Riswan S, Hollingshead MG, Mayo JG, Farnsworth NR, Cordell GA, Kinghorn AD, and Pezzuto JM

Journal of natural products 65(6):842-50, 2002 Jun - Who cited this? | PubMed ID: 12088425 | Fulltext

Pervilleine A, a novel tropane alkaloid that reverses the multidrug-resistance phenotype.

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Mi Q, Cui B, Silva GL, Lantvit D, Lim E, Chai H, You M, Hollingshead MG, Mayo JG, Kinghorn AD, and Pezzuto JM

Cancer research 61(10):4030-7, 2001 May 15 - Who cited this? | PubMed ID: 11358822 | Fulltext

Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol.

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Lam LT, Pickeral OK, Peng AC, Rosenwald A, Hurt EM, Giltnane JM, Averett LM, Zhao H, Davis RE, Sathyamoorthy M, Wahl LM, Harris ED, Mikovits JA, Monks AP, Hollingshead MG, Sausville EA,

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Genome biology 2(10):RESEARCH0041, 2001 - Who cited this? | PubMed ID: 11597333 | Fulltext

The hollow fiber assay: continued characterization with novel approaches.

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Hall LA, Krauthauser CM, Wexler RS, Hollingshead MG, Slee AM, and Kerr JS

Anticancer research 20(2A):903-11, 2000 - Who cited this? | PubMed ID: 10810375 | Fulltext

Murine pharmacokinetics of 6-aminonicotinamide (NSC 21206), a novel biochemical modulating agent.

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Walker DL, Reid JM, Svingen PA, Rios R, Covey JM, Alley MC, Hollingshead MG, Budihardjo II, Eckdahl S, Boerner SA, Kaufmann SH, and Ames MM

Biochemical pharmacology 58(6):1057-66, 1999 Sep 15 - Who cited this? | PubMed ID: 10509758 | Fulltext

Alertenone, a dimer of suberosenone from Alertigorgia sp.

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Bokesch HR, Blunt JW, Westergaard CK, Cardellina JH, Johnson TR, Michael JA, McKee TC, Hollingshead MG, and Boyd MR

Journal of natural products 62(4):633-5, 1999 Apr - Who cited this? | PubMed ID: 10217729 | Fulltext

In vivo anti-HIV activity of (+)-calanolide A in the hollow fiber mouse model.

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Xu ZQ, Hollingshead MG, Borgel S, Elder C, Khilevich A, and Flavin MT

Bioorganic & medicinal chemistry letters 9(2):133-8, 1999 Jan 18 - Who cited this? | PubMed ID: 10021914 | Fulltext

Synthesis and antiviral evaluation of analogs of adenosine-N1-oxide and 1-(Benzyloxy)adenosine.

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Kwong CD, Krauth CA, Shortnacy-Fowler AT, Arnett G, Hollingshead MG, Shannon WM, Montgomery JA, and Secrist JA

Nucleosides & nucleotides 17(8):1409-43, 1998 Aug - Who cited this? | PubMed ID: 9672703 | Fulltext

Inhibition of in vitro and in vivo HIV replication by a distamycin analogue that interferes with chemokine receptor function: a candidate for chemotherapeutic and microbicidal application.

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Howard OM, Oppenheim JJ, Hollingshead MG, Covey JM, Bigelow J, McCormack JJ, Buckheit RW, Clanton DJ, Turpin JA, and Rice WG

Journal of medicinal chemistry 41(13):2184-93, 1998 Jun 18 - Who cited this? | PubMed ID: 9632350 | Fulltext

2-Chloroethyl-3-sarcosinamide-1-nitrosourea, a novel chloroethylnitrosourea analogue with enhanced antitumor activity against human glioma xenografts.

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Marcantonio D, Panasci LC, Hollingshead MG, Alley MC, Camalier RF, Sausville EA, Dykes DJ, Carter CA, and Malspeis L

Cancer research 57(18):3895, 1997 Sep 15 - Who cited this? | PubMed ID: 9307267 | Fulltext

Identification of compounds with preferential inhibitory activity against low-Nm23-expressing human breast carcinoma and melanoma cell lines.

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Freije JM, Lawrence JA, Hollingshead MG, De la Rosa A, Narayanan V, Grever M, Sausville EA, Paull K, and Steeg PS

Nature medicine 3(4):395-401, 1997 Apr - Who cited this? | PubMed ID: 9095172 | Fulltext

Optimization of the reverse transcriptase assay for the detection of viral burden in mice infected with Rauscher murine leukemia virus.

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White EL, Westbrook L, Hollingshead MG, and Shannon WM

Journal of virological methods 62(1):63-70, 1996 Oct - Who cited this? | PubMed ID: 8910649 | Fulltext

In vitro and in vivo enhancement of ddI activity against Rauscher murine leukemia virus by ribavirin.

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Allen LB, Quenelle DC, Westbrook L, Taylor BA, Prichard MN, Brazier AD, Hollingshead MG, and Shannon WM

Antiviral research 27(3):317-23, 1995 Jun - Who cited this? | PubMed ID: 8540752 | Fulltext

In vivo cultivation of tumor cells in hollow fibers.

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Hollingshead MG, Alley MC, Camalier RF, Abbott BJ, Mayo JG, Malspeis L, and Grever MR

Life sciences 57(2):131-41, 1995 - Who cited this? | PubMed ID: 7603295 | Fulltext

Growth and chemotherapeutic response of cells in a hollow-fiber in vitro solid tumor model.

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Casciari JJ, Hollingshead MG, Alley MC, Mayo JG, Malspeis L, Miyauchi S, Grever MR, and Weinstein JN

Journal of the National Cancer Institute 86(24):1846-52, 1994 Dec 21 - Who cited this? | PubMed ID: 7990159 | Fulltext

Differential antiviral activity of two TIBO derivatives against the human immunodeficiency and murine leukemia viruses alone and in combination with other anti-HIV agents.

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Buckheit RW, Germany-Decker J, Hollingshead MG, Allen LB, Shannon WM, Janssen PA, and Chirigos MA

AIDS research and human retroviruses 9(11):1097-106, 1993 Nov - Who cited this? | PubMed ID: 7508723 | Fulltext

Thiazolobenzimidazole: biological and biochemical anti-retroviral activity of a new nonnucleoside reverse transcriptase inhibitor.

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Buckheit RW, Hollingshead MG, Germany-Decker J, White EL, McMahon JB, Allen LB, Ross LJ, Decker WD, Westbrook L, and Shannon WM

Antiviral research 21(3):247-65, 1993 Jul - Who cited this? | PubMed ID: 7692815 | Fulltext

An ELISA system for evaluating antiretroviral activity against Rauscher murine leukemia virus.

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Hollingshead MG, Westbrook L, Ross MJ, Bailey J, Qualls KJ, and Allen LB

Antiviral research 18(3-4):267-74, 1992 Jun - Who cited this? | PubMed ID: 1416908 | Fulltext

Sulfonic acid dyes: inhibition of the human immunodeficiency virus and mechanism of action.

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Clanton DJ, Moran RA, McMahon JB, Weislow OS, Buckheit RW, Hollingshead MG, Ciminale V, Felber BK, Pavlakis GN, and Bader JP

Journal of acquired immune deficiency syndromes 5(8):771-81, 1992 - Who cited this? | PubMed ID: 1517963 | Fulltext

Novel method for evaluating antiviral drugs against human cytomegalovirus in mice.

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Allen LB, Li SX, Arnett G, Toyer B, Shannon WM, and Hollingshead MG

Antimicrobial agents and chemotherapy 36(1):206-8, 1992 Jan - Who cited this? | PubMed ID: 1317146 | Fulltext

A method for the accurate determination of the specificity of monoclonal antibodies reactive with porcine immunoglobulins.

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Hollingshead MG, Tonkonogy SL, and De Buysscher EV

Veterinary immunology and immunopathology 10(2-3):167-75, 1985 Nov - Who cited this? | PubMed ID: 3878620 | Fulltext

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