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Papers authored by Hoffman HM

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Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.

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Lamkanfi M, Mueller JL, Vitari AC, Misaghi S, Fedorova A, Deshayes K, Lee WP, Hoffman HM, and Dixit VM

The Journal of cell biology 187(1):61-70, 2009 Oct 5 - Who cited this? | PubMed ID: 19805629 | Fulltext

Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.

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Brydges SD, Mueller JL, McGeough MD, Pena CA, Misaghi A, Gandhi C, Putnam CD, Boyle DL, Firestein GS, Horner AA, Soroosh P, Watford WT, O'Shea JJ, Kastner DL, and Hoffman HM

Immunity 30(6):875-87, 2009 Jun 19 - Who cited this? | PubMed ID: 19501000 | Fulltext

NLRP3/Cryopyrin Is Necessary for Interleukin-1{beta} (IL-1{beta}) Release in Response to Hyaluronan, an Endogenous Trigger of Inflammation in Response to Injury.

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Yamasaki K, Muto J, Taylor KR, Cogen AL, Audish D, Bertin J, Grant EP, Coyle AJ, Misaghi A, Hoffman HM, and Gallo RL

The Journal of biological chemistry 284(19):12762-71, 2009 May 8 - Who cited this? | PubMed ID: 19258328 | Fulltext

Recurrent febrile syndromes-what a rheumatologist needs to know.

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Hoffman HM and Simon A

Nature reviews. Rheumatology 5(5):249-56, 2009 May - Who cited this? | PubMed ID: 19412191 | Fulltext

Rilonacept for the treatment of cryopyrin-associated periodic syndromes (CAPS).

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Hoffman HM

Expert opinion on biological therapy 9(4):519-31, 2009 Apr - Who cited this? | PubMed ID: 19344287 | Fulltext

Cryopyrin-associated periodic syndromes: development of a patient-reported outcomes instrument to assess the pattern and severity of clinical disease activity.

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Hoffman HM, Wolfe F, Belomestnov P, and Mellis SJ

Current medical research and opinion 24(9):2531-43, 2008 Sep - Who cited this? | PubMed ID: 18667113 | Fulltext

Initial description of the human NLRP3 promoter.

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Anderson JP, Mueller JL, Misaghi A, Anderson S, Sivagnanam M, Kolodner RD, and Hoffman HM

Genes and immunity, 2008 Aug 21 - Who cited this? | PubMed ID: 18719602 | Fulltext

Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies.

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Hoffman HM, Throne ML, Amar NJ, Sebai M, Kivitz AJ, Kavanaugh A, Weinstein SP, Belomestnov P, Yancopoulos GD, Stahl N, and Mellis SJ

Arthritis and rheumatism 58(8):2443, 2008 Aug - Who cited this? | PubMed ID: 18668535 | Fulltext

The infevers autoinflammatory mutation online registry: update with new genes and functions.

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Milhavet F, Cuisset L, Hoffman HM, Slim R, El-Shanti H, Aksentijevich I, Lesage S, Waterham H, Wise C, Sarrauste de Menthiere C, and Touitou I

Human mutation 29(6):803-8, 2008 Jun - Who cited this? | PubMed ID: 18409191 | Fulltext

Identification of EpCAM as the Gene for Congenital Tufting Enteropathy.

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Sivagnanam M, Mueller JL, Lee H, Chen Z, Nelson SF, Turner D, Zlotkin SH, Pencharz PB, Ngan BY, Libiger O, Schork NJ, Lavine JE, Taylor S, Newbury RO, Kolodner RD, and Hoffman HM

Gastroenterology, 2008 May 15 - Who cited this? | PubMed ID: 18572020 | Fulltext

The NLR gene family: a standard nomenclature.

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Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, Flavell RA, Girardin SE, Godzik A, Harton JA, Hoffman HM, Hugot JP, Inohara N, MacKenzie A, Maltais LJ, Nunez G,

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Immunity 28(3):285, 2008 Mar - Who cited this? | PubMed ID: 18341998 | Fulltext

Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC.

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Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, Barnoy S, Venkatesan MM, Flavell RA, Deshmukh M, Hoffman HM, and Ting JP

Cell host & microbe 2(3):147-59, 2007 Sep 13 - Who cited this? | PubMed ID: 18005730 | Fulltext

Hereditary immunologic disorders caused by pyrin and cryopyrin.

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Hoffman HM

Current allergy and asthma reports 7(5):323-30, 2007 Sep - Who cited this? | PubMed ID: 17697637 | Fulltext

MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.

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Pan Q, Mathison J, Fearns C, Kravchenko VV, Da Silva Correia J, Hoffman HM, Kobayashi KS, Bertin J, Grant EP, Coyle AJ, Sutterwala FS, Ogura Y, Flavell RA, and Ulevitch RJ

Journal of leukocyte biology 82(1):177-83, 2007 Jul - Who cited this? | PubMed ID: 17403772 | Fulltext

Monocytes from familial cold autoinflammatory syndrome patients are activated by mild hypothermia.

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Rosengren S, Mueller JL, Anderson JP, Niehaus BL, Misaghi A, Anderson S, Boyle DL, and Hoffman HM

The Journal of allergy and clinical immunology 119(4):991-6, 2007 Apr - Who cited this? | PubMed ID: 17320940 | Fulltext

The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model.

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Aksentijevich I, D Putnam C, Remmers EF, Mueller JL, Le J, Kolodner RD, Moak Z, Chuang M, Austin F, Goldbach-Mansky R, Hoffman HM, and Kastner DL

Arthritis and rheumatism 56(4):1273-85, 2007 Apr - Who cited this? | PubMed ID: 17393462 | Fulltext

Successful treatment of renal amyloidosis due to familial cold autoinflammatory syndrome using an interleukin 1 receptor antagonist.

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Thornton BD, Hoffman HM, Bhat A, and Don BR

American journal of kidney diseases : the official journal of the National Kidney Foundation 49(3):477-81, 2007 Mar - Who cited this? | PubMed ID: 17336710 | Fulltext

Response to IL-1-receptor antagonist in a child with familial cold autoinflammatory syndrome.

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O'Connell SM, O'Regan GM, Bolger T, Hoffman HM, Cant A, Irvine AD, and Watson RM

Pediatric dermatology 24(1):85-9, 2007 - Who cited this? | PubMed ID: 17300660 | Fulltext

Association between celiac sprue and cryopyrin associated autoinflammatory disorders: a case report.

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Shaker M, Edwards S, Chionuma H, Shamansky E, and Hoffman HM

Pediatric rheumatology online journal 5:12, 2007 - Who cited this? | PubMed ID: 17550587 | Fulltext

Educating medical students as competent users of health information technologies: the MSOP data.

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McGowan JJ, Passiment M, and Hoffman HM

Medinfo. MEDINFO 12(Pt 2):1414-8, 2007 - Who cited this? | PubMed ID: 17911947 | Fulltext

Corneal epithelial testing strategies for safety evaluation of ophthalmic formulations.

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Hoffman HM, Choi JH, Clousing DP, Ubels JL, McCarey BE, and Edelhauser HF

Cutaneous and ocular toxicology 26(4):311-27, 2007 - Who cited this? | PubMed ID: 18058306 | Fulltext

Anakinra for the treatment of neonatal-onset multisystem inflammatory disease.

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Hoffman HM and Firestein GS

Nature clinical practice. Rheumatology 2(12):646-7, 2006 Dec - Who cited this? | PubMed ID: 17133246 | Fulltext

Anakinra prevents symptoms of familial cold autoinflammatory syndrome and Raynaud's disease.

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Metyas SK and Hoffman HM

The Journal of rheumatology 33(10):2085-7, 2006 Oct - Who cited this? | PubMed ID: 16981288 | Fulltext

Familial Mediterranean fever (FMF) and beyond: a new horizon. Fourth International Congress on the Systemic Autoinflammatory Diseases held in Bethesda, USA, 6-10 November 2005.

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Ozen S, Hoffman HM, Frenkel J, and Kastner D

Annals of the rheumatic diseases 65(7):961-4, 2006 Jul - Who cited this? | PubMed ID: 16606647 | Fulltext

A severe case of chronic infantile neurologic, cutaneous, articular syndrome treated with biologic agents.

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Matsubara T, Hasegawa M, Shiraishi M, Hoffman HM, Ichiyama T, Tanaka T, Ueda H, Ishihara T, and Furukawa S

Arthritis and rheumatism 54(7):2314-20, 2006 Jul - Who cited this? | PubMed ID: 16802372 | Fulltext

Gene expression in rat lacrimal gland duct cells collected using laser capture microdissection: evidence for K+ secretion by duct cells.

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Ubels JL, Hoffman HM, Srikanth S, Resau JH, and Webb CP

Investigative ophthalmology & visual science 47(5):1876, 2006 May - Who cited this? | PubMed ID: 16638994 | Fulltext

CATERPILLERs, pyrin and hereditary immunological disorders.

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Ting JP, Kastner DL, and Hoffman HM

Nature reviews. Immunology 6(3):183-95, 2006 Mar - Who cited this? | PubMed ID: 16498449 | Fulltext

Autoinflammatory syndromes.

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Galeazzi M, Gasbarrini G, Ghirardello A, Grandemange S, Hoffman HM, Manna R, Podswiadek M, Punzi L, Sebastiani GD, Touitou I, and Doria A

Clinical and experimental rheumatology 24(1 Suppl 40):S79-85, 2006 - Who cited this? | PubMed ID: 16466630 | Fulltext

IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients.

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Stack JH, Beaumont K, Larsen PD, Straley KS, Henkel GW, Randle JC, and Hoffman HM

Journal of immunology (Baltimore, Md. : 1950) 175(4):2630, 2005 Aug 15 - Who cited this? | PubMed ID: 16081838 | Fulltext

Staphylococcus aureus golden pigment impairs neutrophil killing and promotes virulence through its antioxidant activity.

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Liu GY, Essex A, Buchanan JT, Datta V, Hoffman HM, Bastian JF, Fierer J, and Nizet V

The Journal of experimental medicine 202(2):209, 2005 Jul 18 - Who cited this? | PubMed ID: 16009720 | Fulltext

Expression and regulation of cryopyrin and related proteins in rheumatoid arthritis synovium.

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Rosengren S, Hoffman HM, Bugbee W, and Boyle DL

Annals of the rheumatic diseases 64(5):708, 2005 May - Who cited this? | PubMed ID: 15498798 | Fulltext

The clinical course of a child with CINCA/NOMID syndrome improved during and after treatment with thalidomide.

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Kallinich T, Hoffman HM, Roth J, and Keitzer R

Scandinavian journal of rheumatology 34(3):246-9, 2005 - Who cited this? | PubMed ID: 16134734 | Fulltext

Structural, expression, and evolutionary analysis of mouse CIAS1.

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Anderson JP, Mueller JL, Rosengren S, Boyle DL, Schaner P, Cannon SB, Goodyear CS, and Hoffman HM

Gene 338(1):25, 2004 Aug 18 - Who cited this? | PubMed ID: 15302403 | Fulltext

Allelic variants in genes associated with hereditary periodic fever syndromes as susceptibility factors for reactive systemic AA amyloidosis.

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Aganna E, Hawkins PN, Ozen S, Pettersson T, Bybee A, McKee SA, Lachmann HJ, Karenko L, Ranki A, Bakkaloglu A, Besbas N, Topaloglu R, Hoffman HM, Hitman GA, Woo P, and McDermott MF

Genes and immunity 5(4):289-93, 2004 Jun - Who cited this? | PubMed ID: 15071491 | Fulltext

The spectrum of acquired and familial cold-induced urticaria/urticaria-like syndromes.

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Wanderer AA and Hoffman HM

Immunology and allergy clinics of North America 24(2):259-86, vii, 2004 May - Who cited this? | PubMed ID: 15120151 | Fulltext

A case of familial cold autoinflammatory syndrome confirmed by the presence of a CIAS1 mutation.

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Shpall RL, Jeffes EW, and Hoffman HM

The British journal of dermatology 150(5):1029-31, 2004 May - Who cited this? | PubMed ID: 15149524 | Fulltext

Genomic-based therapy: targeting interleukin-1 for autoinflammatory diseases.

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Hoffman HM and Patel DD

Arthritis and rheumatism 50(2):345-9, 2004 Feb - Who cited this? | PubMed ID: 14872474 | Fulltext

Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist.

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Hoffman HM, Rosengren S, Boyle DL, Cho JY, Nayar J, Mueller JL, Anderson JP, Wanderer AA, and Firestein GS

Lancet 364(9447):1779-85, 2004 - Who cited this? | PubMed ID: 15541451 | Fulltext

Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P.

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Hoffman HM, Gregory SG, Mueller JL, Tresierras M, Broide DH, Wanderer AA, and Kolodner RD

Human genetics 112(2):209-16, 2003 Feb - Who cited this? | PubMed ID: 12522564 | Fulltext

A large kindred with familial cold autoinflammatory syndrome.

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Johnstone RF, Dolen WK, and Hoffman HM

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 90(2):233-7, 2003 Feb - Who cited this? | PubMed ID: 12602672 | Fulltext

The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy.

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Knöll R, Hoshijima M, Hoffman HM, Person V, Lorenzen-Schmidt I, Bang ML, Hayashi T, Shiga N, Yasukawa H, Schaper W, McKenna W, Yokoyama M, Schork NJ, Omens JH, McCulloch AD, Kimura A,

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Cell 111(7):943, 2002 Dec 27 - Who cited this? | PubMed ID: 12507422 | Fulltext

Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome.

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Hoffman HM, Mueller JL, Broide DH, Wanderer AA, and Kolodner RD

Nature genetics 29(3):301-5, 2001 Nov - Who cited this? | PubMed ID: 11687797 | Fulltext

Familial cold autoinflammatory syndrome: phenotype and genotype of an autosomal dominant periodic fever.

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Hoffman HM, Wanderer AA, and Broide DH

The Journal of allergy and clinical immunology 108(4):615-20, 2001 Oct - Who cited this? | PubMed ID: 11590390 | Fulltext

Humoral immunodeficiency with facial dysmorphology and limb anomalies: a new syndrome.

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Hoffman HM, Bastian JF, and Bird LM

Clinical dysmorphology 10(1):1-8, 2001 Jan - Who cited this? | PubMed ID: 11152140 | Fulltext

Development of an experimental paradigm in which to examine human learning using two computer-based formats.

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Hoffman HM, Colt HG, and Haas A

Studies in health technology and informatics 81:187-91, 2001 - Who cited this? | PubMed ID: 11317737 | Fulltext

Identification of a locus on chromosome 1q44 for familial cold urticaria.

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Hoffman HM, Wright FA, Broide DH, Wanderer AA, and Kolodner RD

American journal of human genetics 66(5):1693-8, 2000 May - Who cited this? | PubMed ID: 10741953 | Fulltext

Teaching and learning with virtual reality.

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Hoffman HM

Studies in health technology and informatics 79:285-91, 2000 - Who cited this? | PubMed ID: 11151619 | Fulltext

Mast cell adenosine induced calcium mobilization via Gi3 and Gq proteins.

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Hoffman HM, Walker LL, and Marquardt DL

Inflammation 21(1):55-68, 1997 Feb - Who cited this? | PubMed ID: 9179622 | Fulltext

Cultural safety and renal care.

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Hoffman HM

EDTNA/ERCA journal (English ed.) 23(2):44-6, 1997 - Who cited this? | PubMed ID: 9663996 | Fulltext

Developing a virtual reality-multimedia system for anatomy training.

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Hoffman HM, Murray M, Irwin AE, and McCracken T

Studies in health technology and informatics 29:204-10, 1996 - Who cited this? | PubMed ID: 10163751 | Fulltext

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