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Papers authored by Hirayama N

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All-trans-retinoic acid inhibits tumour growth of malignant pleural mesothelioma in mice.

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Tabata C, Tabata R, Hirayama N, Yasumitsu A, Yamada S, Murakami A, Iida S, Tamura K, Terada T, Kuribayashi K, Fukuoka K, and Nakano T

The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 34(5):1159-67, 2009 Nov - Who cited this? | PubMed ID: 19443527 | Fulltext

Organic-solvent/water/ionic-liquid triphasic system for the fractional extraction of divalent metal cations.

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Takata T and Hirayama N

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 25(11):1269-70, 2009 Nov - Who cited this? | PubMed ID: 19907081 | Fulltext

Cooperative intramolecular interaction of diazacrown ether bearing beta-diketone fragments on an ionic liquid extraction system.

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Shimojo K, Okamura H, Hirayama N, Umetani S, Imura H, and Naganawa H

Dalton transactions (Cambridge, England : 2003)(25):4850-2, 2009 Jul 7 - Who cited this? | PubMed ID: 19662274 | Fulltext

Simultaneous determination of azaperone and azaperol in animal tissues by HPLC with confirmation by electrospray ionization mass spectrometry.

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Aoki Y, Hakamata H, Igarashi Y, Uchida K, Kobayashi H, Hirayama N, Kotani A, and Kusu F

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 877(3):166-72, 2009 Jan 15 - Who cited this? | PubMed ID: 19111512 | Fulltext

Extraction Behavior of Divalent Metal Cations in Ionic Liquid Chelate Extraction Systems Using 1-Alkyl-3-methylimidazolium Bis(trifluoromethanesulfonyl)imides and Thenoyltrifluoroacetone.

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Kidani K, Hirayama N, and Imura H

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 24(10):1251-4, 2008 Oct - Who cited this? | PubMed ID: 18845882 | Fulltext

Hepatic Lesions Caused by Migrating Larvae of Ascaris suum in chickens.

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Yoshihara S, Hattori J, Nishizono K, Kawamura A, Shimozaki K, Nishida Y, Oda K, Tsuji N, and Hirayama N

The Journal of veterinary medical science / the Japanese Society of Veterinary Science 70(10):1129-31, 2008 Oct - Who cited this? | PubMed ID: 18981674 | Fulltext

Validation and standardization of virus neutralizing test using indirect immunoperoxidase technique for the quantification of antibodies to rabies virus.

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Ogawa T, Gamoh K, Aoki H, Kobayashi R, Etoh M, Senda M, Hirayama N, Nishimura M, Shiraishi R, Servat A, and Cliquet F

Zoonoses and public health 55(6):323-7, 2008 Aug - Who cited this? | PubMed ID: 18489544 | Fulltext

Chemocavity: specific concavity in protein reserved for the binding of biologically functional small molecules.

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Soga S, Shirai H, Kobori M, and Hirayama N

Journal of chemical information and modeling 48(8):1679-85, 2008 Aug - Who cited this? | PubMed ID: 18642867 | Fulltext

Ionic Liquid Synergistic Cation-Exchange System for the Selective Extraction of Lanthanum(III) Using 2-Thenoyltrifluoroacetone and 18-Crown-6.

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Hirayama N, Okamura H, Kidani K, and Imura H

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 24(6):697-9, 2008 Jun - Who cited this? | PubMed ID: 18544855 | Fulltext

Up-regulation of p21CIP1 expression mediated by ERK-dependent and -independent pathways contributes to hepatocyte growth factor-induced inhibition of HepG2 hepatoma cell proliferation.

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Shirako E, Hirayama N, Tsukada Y, Tanaka T, and Kitamura N

Journal of cellular biochemistry 104(1):176-88, 2008 May 1 - Who cited this? | PubMed ID: 18004740 | Fulltext

Inhibition of plasminogen activator inhibitor-1: its mechanism and effectiveness on coagulation and fibrosis.

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Izuhara Y, Takahashi S, Nangaku M, Takizawa S, Ishida H, Kurokawa K, van Ypersele de Strihou C, Hirayama N, and Miyata T

Arteriosclerosis, thrombosis, and vascular biology 28(4):672-7, 2008 Apr - Who cited this? | PubMed ID: 18239154 | Fulltext

ASEDock-Docking Based on Alpha Spheres and Excluded Volumes.

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Goto J, Kataoka R, Muta H, and Hirayama N

Journal of chemical information and modeling 48(3):583-90, 2008 Mar - Who cited this? | PubMed ID: 18278891 | Fulltext

Coupling of Grb2 to Gab1 Mediates Hepatocyte Growth Factor-induced High Intensity ERK Signal Required for Inhibition of HepG2 Hepatoma Cell Proliferation.

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Kondo A, Hirayama N, Sugito Y, Shono M, Tanaka T, and Kitamura N

The Journal of biological chemistry 283(3):1428-36, 2008 Jan 18 - Who cited this? | PubMed ID: 18003605 | Fulltext

Use of 8-sulfonamidoquinoline derivatives as chelate extraction reagents in ionic liquid extraction system.

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Ajioka T, Oshima S, and Hirayama N

Talanta 74(4):903-8, 2008 Jan 15 - Who cited this? | PubMed ID: 18371726 | Fulltext

A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts organ protection against ischemia.

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Nangaku M, Izuhara Y, Takizawa S, Yamashita T, Fujii-Kuriyama Y, Ohneda O, Yamamoto M, van Ypersele de Strihou C, Hirayama N, and Miyata T

Arteriosclerosis, thrombosis, and vascular biology 27(12):2548-54, 2007 Dec - Who cited this? | PubMed ID: 17932321 | Fulltext

Severe brainstem compression by an unruptured giant vertebral aneurysm--an autopsy case.

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Hayashi T, Hirayama N, Ro A, Kageyama N, Ishida Y, Tsuneyama K, Kimura A, Fukunaga T, and Kondo T

Legal medicine (Tokyo, Japan) 9(6):322-5, 2007 Nov - Who cited this? | PubMed ID: 17562378 | Fulltext

Liquid chromatography-tandem mass spectrometric method for determination of mosapride citrate in equine tissues.

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Aoki Y, Hakamata H, Igarashi Y, Uchida K, Kobayashi H, Hirayama N, Kotani A, and Kusu F

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 858(1-2):135-42, 2007 Oct 15 - Who cited this? | PubMed ID: 17851144 | Fulltext

A simple method to improve the odds in finding 'lead-like' compounds from chemical libraries.

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Horio K, Muta H, Goto J, and Hirayama N

Chemical & pharmaceutical bulletin 55(7):980-4, 2007 Jul - Who cited this? | PubMed ID: 17603185 | Fulltext

Megsin gene: its genomic analysis, pathobiological functions, and therapeutic perspectives.

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Miyata T, Li M, Yu X, and Hirayama N

Current genomics 8(3):203-8, 2007 May - Who cited this? | PubMed ID: 18645605 | Fulltext

[Virtual screening based on protein-ligand interactions].

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Hirayama N

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 127(1):101-2, 2007 Jan - Who cited this? | PubMed ID: 17202789 | Fulltext

[Docking method for drug discovery].

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Hirayama N

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 127(1):113-22, 2007 Jan - Who cited this? | PubMed ID: 17202791 | Fulltext

Use of amino acid composition to predict ligand-binding sites.

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Soga S, Shirai H, Kobori M, and Hirayama N

Journal of chemical information and modeling 47(2):400-6, 2007 - Who cited this? | PubMed ID: 17243757 | Fulltext

Identification of the druggable concavity in homology models using the PLB index.

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Soga S, Shirai H, Kobori M, and Hirayama N

Journal of chemical information and modeling 47(6):2287-92, 2007 - Who cited this? | PubMed ID: 17935312 | Fulltext

Construction of an additional metal-binding site in human metallothionein-2.

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Toyama M, Sasaki M, Hirayama N, Murooka Y, and Yamashita M

Journal of bioscience and bioengineering 101(4):354-60, 2006 Apr - Who cited this? | PubMed ID: 16716945 | Fulltext

G-CSF receptor-binding cyclic peptides designed with artificial amino-acid linkers.

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Shibata K, Maruyama-Takahashi K, Yamasaki M, and Hirayama N

Biochemical and biophysical research communications 341(2):483-8, 2006 Mar 10 - Who cited this? | PubMed ID: 16427611 | Fulltext

Halogen-free water-immiscible ionic liquids based on tetraoctylammonium cation and dodecylsulfate and dodecylbenzenesulfonate anions, and their application as chelate extraction solvent.

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Tsukatani T, Katano H, Tatsumi H, Deguchi M, and Hirayama N

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 22(2):199-200, 2006 Feb - Who cited this? | PubMed ID: 16512407 | Fulltext

Prediction of solvents suitable for crystallization of small organic molecules.

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Hosokawa K, Goto J, and Hirayama N

Chemical & pharmaceutical bulletin 53(10):1296-9, 2005 Oct - Who cited this? | PubMed ID: 16204986 | Fulltext

Regimen of tacrolimus-based immunosuppression with basiliximab, mycophenolate mofetil, and low-dose steroid reduces acute rejection in kidney transplants.

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Hoshinaga K, Aikawa A, Murai M, Yamamoto H, Hirayama N, Shishido S, and Hasegawa A

Transplantation proceedings 37(4):1762-3, 2005 May - Who cited this? | PubMed ID: 15919457 | Fulltext

Reversibility from delayed hyperacute rejection in ABO-incompatible renal transplantation: histopathological findings of renal allograft biopsy.

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Sugiyama K, Arai K, Aikawa A, Miyagi M, Ohara T, Hasegawa A, Muramatsu M, Hirayama N, Tajima E, Kawamura T, Ogihara H, Hadano T, and Nakano H

Transplantation proceedings 37(2):701-4, 2005 Mar - Who cited this? | PubMed ID: 15848507 | Fulltext

Prediction of solubility of drugs by conductor-like screening model for real solvents.

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Ikeda H, Chiba K, Kanou A, and Hirayama N

Chemical & pharmaceutical bulletin 53(2):253-5, 2005 Feb - Who cited this? | PubMed ID: 15684531 | Fulltext

Molecular mechanism of dielectrically controlled optical resolution (DCR).

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Sakai K, Sakurai R, Akimoto T, and Hirayama N

Organic & biomolecular chemistry 3(2):360-5, 2005 Jan 21 - Who cited this? | PubMed ID: 15632979 | Fulltext

Use of 1-alkyl-3-methylimidazolium hexafluorophosphate room temperature ionic liquids as chelate extraction solvent with 4,4,4-trifluoro-1-(2-thienyl)-1,3-butanedione.

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Hirayama N, Deguchi M, Kawasumi H, and Honjo T

Talanta 65(1):255-60, 2005 Jan 15 - Who cited this? | PubMed ID: 18969792 | Fulltext

Investigating serum factors promoting erythrocytic growth of Plasmodium falciparum.

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Asahi H, Kanazawa T, Hirayama N, and Kajihara Y

Experimental parasitology 109(1):7-15, 2005 Jan - Who cited this? | PubMed ID: 15639134 | Fulltext

Inhibitory remnant stomach motility by duodenal distention after B-I gastrectomy.

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Hirayama N, Gunji Y, Miyazaki S, Kaiho T, Shimada H, Matsubara H, Nabeya Y, Aoki T, Kobayashi S, and Ochiai T

Hepato-gastroenterology 52(62):633-8, 2005 - Who cited this? | PubMed ID: 15816494 | Fulltext

High en bloc resection rate achieved by endoscopic mucosal resection with IT knife for early gastric cancer.

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Miyazaki S, Gunji Y, Aoki T, Nakajima K, Nabeya Y, Hayashi H, Shimada H, Uesato M, Hirayama N, Karube T, Akai T, Nikaidou T, Kouzu T, and Ochiai T

Hepato-gastroenterology 52(63):954-8, 2005 - Who cited this? | PubMed ID: 15966240 | Fulltext

Antitumor effects of synthetic VEGF-receptor binding antagonist, VGA1155.

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Ueda Y, Yamagishi T, Samata K, Hirayama N, Aozuka Y, Tanaka M, Nakaike S, and Saiki I

Anticancer research 25(6B):3973-7, 2005 - Who cited this? | PubMed ID: 16309186 | Fulltext

Ph4Dock: pharmacophore-based protein-ligand docking.

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Goto J, Kataoka R, and Hirayama N

Journal of medicinal chemistry 47(27):6804-11, 2004 Dec 30 - Who cited this? | PubMed ID: 15615529 | Fulltext

A novel low molecular weight VEGF receptor-binding antagonist, VGA1102, inhibits the function of VEGF and in vivo tumor growth.

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Ueda Y, Yamagishi T, Samata K, Ikeya H, Hirayama N, Okazaki T, Nishihara S, Arai K, Yamaguchi S, Shibuya M, Nakaike S, and Tanaka M

Cancer chemotherapy and pharmacology 54(1):16-24, 2004 Jul - Who cited this? | PubMed ID: 15064856 | Fulltext

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.

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Takeuchi T, Kushida M, Hirayama N, Kitayama M, Fujita A, and Hata F

British journal of pharmacology 142(4):657-66, 2004 Jun - Who cited this? | PubMed ID: 15159278 | Fulltext

Effect of the anastomosis-site after Billroth I gastrectomy on the motility of the remnant stomach.

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Kaiho T, Gunji Y, Hirayama N, Hayashi H, Miyazaki S, Shimada H, Nabeya Y, Matsubara H, Kobayashi S, and Ochiai T

Hepato-gastroenterology 51(57):906-11, 2004 - Who cited this? | PubMed ID: 15143944 | Fulltext

VGA1155, a novel binding antagonist of VEGF, inhibits angiogenesis in vitro and in vivo.

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Ueda Y, Yamagishi T, Ikeya H, Hirayama N, Itokawa T, Aozuka Y, Samata K, Nakaike S, Tanaka M, Ono M, and Saiki I

Anticancer research 24(5A):3009-17, 2004 - Who cited this? | PubMed ID: 15517909 | Fulltext

Cardiac amyloidosis associated with a novel transthyretin aspartic acid-18 glutamic acid de novo mutation.

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Imamura T, Nakazato M, Date Y, Komatsu H, Ashizuka S, Aoyama F, Sumi M, Tsuruda T, Ishikawa T, Hirayama N, Matsuo T, and Eto T

Circulation journal : official journal of the Japanese Circulation Society 67(11):965-8, 2003 Nov - Who cited this? | PubMed ID: 14578606 | Fulltext

A novel low molecular weight antagonist of vascular endothelial growth factor receptor binding: VGA1155.

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Ueda Y, Yamagishi T, Samata K, Ikeya H, Hirayama N, Takashima H, Nakaike S, Tanaka M, and Saiki I

Molecular cancer therapeutics 2(11):1105-11, 2003 Nov - Who cited this? | PubMed ID: 14617783 | Fulltext

Establishment of a potency test by ELISA for a rabies vaccine for animal use in Japan.

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Gamoh K, Shimazaki Y, Senda M, Makie H, Itoh O, Muramatsu M, Hirayama N, and Hatakeyama H

The Journal of veterinary medical science / the Japanese Society of Veterinary Science 65(6):685-8, 2003 Jun - Who cited this? | PubMed ID: 12867727 | Fulltext

Ion-pair extraction behavior of divalent metal cations using neutral di-Schiff base ligands derived from 1,2-cyclohexanediamine and o-phenylenediamine.

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Oshima S, Hirayama N, Kubono K, Kokusen H, and Honjo T

Talanta 59(5):867-74, 2003 Apr 10 - Who cited this? | PubMed ID: 18968974 | Fulltext

Crystal structure of [1,4-bis[1-(3,5-dichlorophenolato-2-ylmethyl)-ylpropylamino-kappa2N,O]piperazine-kappa2N,N']cobalt(II).

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Kubono K, Hirayama N, Kokusen H, and Yokoi K

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 19(4):645-6, 2003 Apr - Who cited this? | PubMed ID: 12725412 | Fulltext

Endoscopic mucosal resection of adenocarcinoma arising in ectopic gastric mucosa in the cervical esophagus: case report.

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Hirayama N, Arima M, Miyazaki S, Shimada H, Okazumi S, Matsubara H, Suzuki T, Ochiai T, and Kouzu T

Gastrointestinal endoscopy 57(2):263-6, 2003 Feb - Who cited this? | PubMed ID: 12556801 | Fulltext

"Substituent on benzenesulfonyl group" effect in use of 8-benzenesulfonamidoquinoline derivatives as chelate extractant.

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Hirayama N, Sugisaka N, Taga J, Oshima S, and Honjo T

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 19(2):321-4, 2003 Feb - Who cited this? | PubMed ID: 12608768 | Fulltext

Crude oil bioremediation field experiment in the Sea of Japan.

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Maki H, Hirayama N, Hiwatari T, Kohata K, Uchiyama H, Watanabe M, Yamasaki F, and Furuki M

Marine pollution bulletin 47(1-6):74-7, 2003 - Who cited this? | PubMed ID: 12787600 | Fulltext

Structural control of Schiff base ligands for selective extraction of copper(II).

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Oshima S, Hirayama N, Kubono K, Kokusen H, and Honjo T

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 18(12):1351-5, 2002 Dec - Who cited this? | PubMed ID: 12502088 | Fulltext

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