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Papers authored by Hangoc G

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Experimental basis of cord blood transplantation.

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Broxmeyer HE, Cooper S, Hass DM, Hathaway JK, Stehman FB, and Hangoc G

Bone marrow transplantation 44(10):627-33, 2009 Nov - Who cited this? | PubMed ID: 19802026 | Fulltext

Overexpression of Rheb2 enhances mouse hematopoietic progenitor cell growth while impairing stem cell repopulation.

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Campbell TB, Basu S, Hangoc G, Tao W, and Broxmeyer HE

Blood 114(16):3392-401, 2009 Oct 15 - Who cited this? | PubMed ID: 19690340 | Fulltext

Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis.

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Stumpo DJ, Broxmeyer HE, Ward T, Cooper S, Hangoc G, Chung YJ, Shelley WC, Richfield EK, Ray MK, Yoder MC, Aplan PD, and Blackshear PJ

Blood 114(12):2401-10, 2009 Sep 17 - Who cited this? | PubMed ID: 19633199 | Fulltext

Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34(+) NOD/SCID-repopulating cells.

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Liu Y, Hangoc G, Campbell TB, Goodman M, Tao W, Pollok K, Srour EF, and Broxmeyer HE

Experimental hematology 36(8):947, 2008 Aug - Who cited this? | PubMed ID: 18640494 | Fulltext

SDF-1/CXCL12 enhances in vitro replating capacity of murine and human multipotential and macrophage progenitor cells.

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Broxmeyer HE, Mejia JA, Hangoc G, Barese C, Dinauer M, and Cooper S

Stem cells and development 16(4):589-96, 2007 Aug - Who cited this? | PubMed ID: 17784832 | Fulltext

Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice.

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Campbell TB, Hangoc G, Liu Y, Pollok K, and Broxmeyer HE

Stem cells and development 16(3):347, 2007 Jun - Who cited this? | PubMed ID: 17610364 | Fulltext

AMD3100 and CD26 modulate mobilization, engraftment, and survival of hematopoietic stem and progenitor cells mediated by the SDF-1/CXCL12-CXCR4 axis.

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Broxmeyer HE, Hangoc G, Cooper S, Campbell T, Ito S, and Mantel C

Annals of the New York Academy of Sciences 1106:1, 2007 Jun - Who cited this? | PubMed ID: 17360804 | Fulltext

Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31.

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Broxmeyer HE, Li J, Hangoc G, Cooper S, Tao W, Mantel C, Graham-Evans B, Ghilardi N, and de Sauvage FJ

Experimental hematology 35(4 Suppl 1):78-86, 2007 Apr - Who cited this? | PubMed ID: 17379091 | Fulltext

A role for natural killer T cells and CD1d molecules in counteracting suppression of hematopoiesis in mice induced by infection with murine cytomegalovirus.

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Broxmeyer HE, Dent A, Cooper S, Hangoc G, Wang ZY, Du W, Gervay-Haque J, Sriram V, Renukaradhya GJ, and Brutkiewicz RR

Experimental hematology 35(4 Suppl 1):87-93, 2007 Apr - Who cited this? | PubMed ID: 17379092 | Fulltext

Enhanced green fluorescent protein is a nearly ideal long-term expression tracer for hematopoietic stem cells, whereas DsRed-express fluorescent protein is not.

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Tao W, Evans BG, Yao J, Cooper S, Cornetta K, Ballas CB, Hangoc G, and Broxmeyer HE

Stem cells (Dayton, Ohio) 25(3):670, 2007 Mar - Who cited this? | PubMed ID: 17138958 | Fulltext

Synergistic inhibition in vivo of bone marrow myeloid progenitors by myelosuppressive chemokines and chemokine-accelerated recovery of progenitors after treatment of mice with Ara-C.

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Broxmeyer HE, Pelus LM, Kim CH, Hangoc G, Cooper S, and Hromas R

Experimental hematology 34(8):1069-77, 2006 Aug - Who cited this? | PubMed ID: 16863913 | Fulltext

Class II transactivator-mediated regulation of major histocompatibility complex class II antigen expression is important for hematopoietic progenitor cell suppression by chemokines and iron-binding proteins.

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Broxmeyer HE, Cooper S, Hangoc G, and Chang CH

Experimental hematology 34(8):1078-84, 2006 Aug - Who cited this? | PubMed ID: 16863914 | Fulltext

Enhanced functional response to CXCL12/SDF-1 through retroviral overexpression of CXCR4 on M07e cells: implications for hematopoietic stem cell transplantation.

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Porecha NK, English K, Hangoc G, Broxmeyer HE, and Christopherson KW

Stem cells and development 15(3):325, 2006 Jun - Who cited this? | PubMed ID: 16846371 | Fulltext

SDF-1/CXCL12 enhances survival and chemotaxis of murine embryonic stem cells and production of primitive and definitive hematopoietic progenitor cells.

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Guo Y, Hangoc G, Bian H, Pelus LM, and Broxmeyer HE

Stem cells (Dayton, Ohio) 23(9):1324, 2005 Oct - Who cited this? | PubMed ID: 16210409 | Fulltext

Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist.

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Broxmeyer HE, Orschell CM, Clapp DW, Hangoc G, Cooper S, Plett PA, Liles WC, Li X, Graham-Evans B, Campbell TB, Calandra G, Bridger G, Dale DC, and Srour EF

The Journal of experimental medicine 201(8):1307-18, 2005 Apr 18 - Who cited this? | PubMed ID: 15837815 | Fulltext

Stromal cell-derived factor-1/CXCL12 selectively counteracts inhibitory effects of myelosuppressive chemokines on hematopoietic progenitor cell proliferation in vitro.

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Broxmeyer HE, Cooper S, Hangoc G, and Kim CH

Stem cells and development 14(2):199-203, 2005 Apr - Who cited this? | PubMed ID: 15910246 | Fulltext

Constitutive expression of CIITA directs CD4 T cells to produce Th2 cytokines in the thymus.

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Patel DR, Li W, Park JS, Sofi MH, Gourley TS, Hangoc G, Kaplan MH, and Chang CH

Cellular immunology 233(1):30-40, 2005 Jan - Who cited this? | PubMed ID: 15876426 | Fulltext

Interleukin-10 in combination with M-CSF and IL-4 contributes to development of the rare population of CD14+CD16++ cells derived from human monocytes.

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Li G, Hangoc G, and Broxmeyer HE

Biochemical and biophysical research communications 322(2):637-43, 2004 Sep 17 - Who cited this? | PubMed ID: 15325277 | Fulltext

Modulation of hematopoietic stem cell homing and engraftment by CD26.

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Christopherson KW, Hangoc G, Mantel CR, and Broxmeyer HE

Science (New York, N.Y.) 305(5686):1000-3, 2004 Aug 13 - Who cited this? | PubMed ID: 15310902 | Fulltext

Leukocytosis and Mobilization of CD34+ Hematopoietic Progenitor Cells by AMD3100, a CXCR4 Antagonist.

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Hübel K, Liles WC, Broxmeyer HE, Rodger E, Wood B, Cooper S, Hangoc G, Macfarland R, Bridger GJ, Henson GW, Calandra G, and Dale DC

Supportive cancer therapy 1(3):165-72, 2004 Apr 1 - Who cited this? | PubMed ID: 18628138 | Fulltext

SDF-1alpha/CXCL12 enhances retroviral-mediated gene transfer into immature subsets of human and murine hematopoietic progenitor cells.

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Tao W, Hangoc G, Cooper S, and Broxmeyer HE

Gene therapy 11(1):61-9, 2004 Jan - Who cited this? | PubMed ID: 14681698 | Fulltext

Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20.

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Liu L, Ding C, Zeng W, Heuer JG, Tetreault JW, Noblitt TW, Hangoc G, Cooper S, Brune KA, Sharma G, Fox N, Rowlinson SW, Rogers DP, Witcher DR, Lambooy PK, Wroblewski VJ,

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Blood 102(9):3206-9, 2003 Nov 1 - Who cited this? | PubMed ID: 12855566 | Fulltext

CD26 is essential for normal G-CSF-induced progenitor cell mobilization as determined by CD26-/- mice.

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Christopherson KW, Cooper S, Hangoc G, and Broxmeyer HE

Experimental hematology 31(11):1126-34, 2003 Nov - Who cited this? | PubMed ID: 14585379 | Fulltext

Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist.

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Liles WC, Broxmeyer HE, Rodger E, Wood B, Hübel K, Cooper S, Hangoc G, Bridger GJ, Henson GW, Calandra G, and Dale DC

Blood 102(8):2728-30, 2003 Oct 15 - Who cited this? | PubMed ID: 12855591 | Fulltext

Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and G(alpha)i proteins and enhances engraftment of competitive, repopulating stem cells.

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Broxmeyer HE, Kohli L, Kim CH, Lee Y, Mantel C, Cooper S, Hangoc G, Shaheen M, Li X, and Clapp DW

Journal of leukocyte biology 73(5):630-8, 2003 May - Who cited this? | PubMed ID: 12714578 | Fulltext

Profiling of differentially expressed apoptosis-related genes by cDNA arrays in human cord blood CD34+ cells treated with etoposide.

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Tao W, Hangoc G, Hawes JW, Si Y, Cooper S, and Broxmeyer HE

Experimental hematology 31(3):251-60, 2003 Mar - Who cited this? | PubMed ID: 12644023 | Fulltext

High-efficiency recovery of functional hematopoietic progenitor and stem cells from human cord blood cryopreserved for 15 years.

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Broxmeyer HE, Srour EF, Hangoc G, Cooper S, Anderson SA, and Bodine DM

Proceedings of the National Academy of Sciences of the United States of America 100(2):645-50, 2003 Jan 21 - Who cited this? | PubMed ID: 12518050 | Fulltext

Transgenic expression of stromal cell-derived factor-1/CXC chemokine ligand 12 enhances myeloid progenitor cell survival/antiapoptosis in vitro in response to growth factor withdrawal and enhances myelopoiesis in vivo.

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Broxmeyer HE, Cooper S, Kohli L, Hangoc G, Lee Y, Mantel C, Clapp DW, and Kim CH

Journal of immunology (Baltimore, Md. : 1950) 170(1):421-9, 2003 Jan 1 - Who cited this? | PubMed ID: 12496427 | Fulltext

Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/stromal cell-derived factor-1 alpha-mediated chemotaxis of human cord blood CD34+ progenitor cells.

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Christopherson KW, Hangoc G, and Broxmeyer HE

Journal of immunology (Baltimore, Md. : 1950) 169(12):7000-8, 2002 Dec 15 - Who cited this? | PubMed ID: 12471135 | Fulltext

Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines.

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Lee Y, Gotoh A, Kwon HJ, You M, Kohli L, Mantel C, Cooper S, Hangoc G, Miyazawa K, Ohyashiki K, and Broxmeyer HE

Blood 99(12):4307-17, 2002 Jun 15 - Who cited this? | PubMed ID: 12036856 | Fulltext

Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin M.

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Broxmeyer HE, Bruns HA, Zhang S, Cooper S, Hangoc G, McKenzie AN, Dent AL, Schindler U, Naeger LK, Hoey T, and Kaplan MH

Immunity 16(6):815-25, 2002 Jun - Who cited this? | PubMed ID: 12121663 | Fulltext

Chemokine regulation of hematopoiesis and the involvement of pertussis toxin-sensitive G alpha i proteins.

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Broxmeyer HE, Youn BS, Kim C, Hangoc G, Cooper S, and Mantel C

Annals of the New York Academy of Sciences 938:117-27; discussion 127-8, 2001 Jun - Who cited this? | PubMed ID: 11458498 | Fulltext

Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling.

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Zhang S, Fukuda S, Lee Y, Hangoc G, Cooper S, Spolski R, Leonard WJ, and Broxmeyer HE

The Journal of experimental medicine 192(5):719-28, 2000 Sep 4 - Who cited this? | PubMed ID: 10974037 | Fulltext

The exodus subfamily of CC chemokines inhibits the proliferation of chronic myelogenous leukemia progenitors.

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Hromas R, Cripe L, Hangoc G, Cooper S, and Broxmeyer HE

Blood 95(4):1506-8, 2000 Feb 15 - Who cited this? | PubMed ID: 10666233 | Fulltext

Altered responsiveness to chemokines due to targeted disruption of SHIP.

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Kim CH, Hangoc G, Cooper S, Helgason CD, Yew S, Humphries RK, Krystal G, and Broxmeyer HE

The Journal of clinical investigation 104(12):1751-9, 1999 Dec - Who cited this? | PubMed ID: 10606629 | Fulltext

Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses.

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Kim CH, Qu CK, Hangoc G, Cooper S, Anzai N, Feng GS, and Broxmeyer HE

The Journal of experimental medicine 190(5):681-90, 1999 Sep 6 - Who cited this? | PubMed ID: 10477552 | Fulltext

Dominant myelopoietic effector functions mediated by chemokine receptor CCR1.

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Broxmeyer HE, Cooper S, Hangoc G, Gao JL, and Murphy PM

The Journal of experimental medicine 189(12):1987-92, 1999 Jun 21 - Who cited this? | PubMed ID: 10377195 | Fulltext

Effects of CC, CXC, C, and CX3C chemokines on proliferation of myeloid progenitor cells, and insights into SDF-1-induced chemotaxis of progenitors.

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Broxmeyer HE, Kim CH, Cooper SH, Hangoc G, Hromas R, and Pelus LM

Annals of the New York Academy of Sciences 872:142-62; discussion 163, 1999 Apr 30 - Who cited this? | PubMed ID: 10372118 | Fulltext

Enhanced myeloid progenitor cell cycling and apoptosis in mice lacking the chemokine receptor, CCR2.

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Reid S, Ritchie A, Boring L, Gosling J, Cooper S, Hangoc G, Charo IF, and Broxmeyer HE

Blood 93(5):1524-33, 1999 Mar 1 - Who cited this? | PubMed ID: 10029580 | Fulltext

p21(cip-1/waf-1) deficiency causes deformed nuclear architecture, centriole overduplication, polyploidy, and relaxed microtubule damage checkpoints in human hematopoietic cells.

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Mantel C, Braun SE, Reid S, Henegariu O, Liu L, Hangoc G, and Broxmeyer HE

Blood 93(4):1390-8, 1999 Feb 15 - Who cited this? | PubMed ID: 9949183 | Fulltext

Isolation and characterization of LMC, a novel lymphocyte and monocyte chemoattractant human CC chemokine, with myelosuppressive activity.

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Youn BS, Zhang S, Broxmeyer HE, Antol K, Fraser MJ, Hangoc G, and Kwon BS

Biochemical and biophysical research communications 247(2):217-22, 1998 Jun 18 - Who cited this? | PubMed ID: 9642106 | Fulltext

Multiple inhibitory cytokines induce deregulated progenitor growth and apoptosis in hematopoietic cells from Fac-/- mice.

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Haneline LS, Broxmeyer HE, Cooper S, Hangoc G, Carreau M, Buchwald M, and Clapp DW

Blood 91(11):4092-8, 1998 Jun 1 - Who cited this? | PubMed ID: 9596654 | Fulltext

The contribution of animal models to the development of treatments for hematologic recovery following myeloablative therapy: a review.

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Schneidkraut MJ, Hangoc G, Bender JG, and Huntenburg CC

Journal of hematotherapy 5(6):631-46, 1996 Dec - Who cited this? | PubMed ID: 9117252 | Fulltext

Separation of clinical quantities of CD34+ cells from human marrow using immunomagnetic procedures.

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Burgess J, Traycoff C, Hardwick A, Smith A, Hangoc G, Ishizawa L, Moubayed M, Broun R, Srour E, and Gee A

Progress in clinical and biological research 389:293-302, 1994 - Who cited this? | PubMed ID: 7535434 | Fulltext

Regulation of myelopoiesis by murine fibroblastic and adipogenic cell lines.

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Hangoc G, Daub R, Maze RG, Falkenburg JH, Broxmeyer HE, and Harrington MA

Experimental hematology 21(4):502-7, 1993 Apr - Who cited this? | PubMed ID: 8462659 | Fulltext

Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: an effect enhanced by cord blood plasma.

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Carow CE, Hangoc G, and Broxmeyer HE

Blood 81(4):942-9, 1993 Feb 15 - Who cited this? | PubMed ID: 7679010 | Fulltext

In vivo effects of recombinant interleukin-11 on myelopoiesis in mice.

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Hangoc G, Yin T, Cooper S, Schendel P, Yang YC, and Broxmeyer HE

Blood 81(4):965-72, 1993 Feb 15 - Who cited this? | PubMed ID: 8428003 | Fulltext

Immunomagnetic separation of CD34+ cells from human bone marrow, cord blood, and mobilized peripheral blood.

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Ishizawa L, Hangoc G, Van de Ven C, Cairo M, Burgess J, Mansour V, Gee A, Hardwick A, Traycoff C, and Srour E

Journal of hematotherapy 2(3):333-8, 1993 - Who cited this? | PubMed ID: 7522887 | Fulltext

Effects in vivo of recombinant human inhibin on myelopoiesis in mice.

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Hangoc G, Carow CE, Schwall R, Mason AJ, and Broxmeyer HE

Experimental hematology 20(10):1243-6, 1992 Nov - Who cited this? | PubMed ID: 1426104 | Fulltext

Increased osteoclast development after estrogen loss: mediation by interleukin-6.

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Jilka RL, Hangoc G, Girasole G, Passeri G, Williams DC, Abrams JS, Boyce B, Broxmeyer H, and Manolagas SC

Science (New York, N.Y.) 257(5066):88-91, 1992 Jul 3 - Who cited this? | PubMed ID: 1621100 | Fulltext

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