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Papers authored by Hamatake RK

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Entecavir for treatment of hepatitis B virus displays no in vitro mitochondrial toxicity or DNA polymerase gamma inhibition.

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Mazzucco CE, Hamatake RK, Colonno RJ, and Tenney DJ

Antimicrobial agents and chemotherapy 52(2):598-605, 2008 Feb - Who cited this? | PubMed ID: 18056280 | Fulltext

6-Hydrazinopurine 2'-methyl ribonucleosides and their 5'-monophosphate prodrugs as potent hepatitis C virus inhibitors.

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Gunic E, Chow S, Rong F, Ramasamy K, Raney A, Li DY, Huang J, Hamatake RK, Hong Z, and Girardet JL

Bioorganic & medicinal chemistry letters 17(9):2456-8, 2007 May 1 - Who cited this? | PubMed ID: 17331718 | Fulltext

Cyclic monophosphate prodrugs of base-modified 2'-C-methyl ribonucleosides as potent inhibitors of hepatitis C virus RNA replication.

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Gunic E, Girardet JL, Ramasamy K, Stoisavljevic-Petkov V, Chow S, Yeh LT, Hamatake RK, Raney A, and Hong Z

Bioorganic & medicinal chemistry letters 17(9):2452-5, 2007 May 1 - Who cited this? | PubMed ID: 17331721 | Fulltext

Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: convergence of structure-based drug design and X-ray crystallographic study.

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Yan S, Appleby T, Larson G, Wu JZ, Hamatake RK, Hong Z, and Yao N

Bioorganic & medicinal chemistry letters 17(7):1991-5, 2007 Apr 1 - Who cited this? | PubMed ID: 17276060 | Fulltext

A novel nonnucleoside analogue that inhibits human immunodeficiency virus type 1 isolates resistant to current nonnucleoside reverse transcriptase inhibitors.

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Zhang Z, Xu W, Koh YH, Shim JH, Girardet JL, Yeh LT, Hamatake RK, and Hong Z

Antimicrobial agents and chemotherapy 51(2):429-37, 2007 Feb - Who cited this? | PubMed ID: 17116677 | Fulltext

Novel nonnucleoside inhibitors that select nucleoside inhibitor resistance mutations in human immunodeficiency virus type 1 reverse transcriptase.

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Zhang Z, Walker M, Xu W, Shim JH, Girardet JL, Hamatake RK, and Hong Z

Antimicrobial agents and chemotherapy 50(8):2772, 2006 Aug - Who cited this? | PubMed ID: 16870771 | Fulltext

HEP DART 2003: Frontiers in drug development for viral hepatitis.

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Raney AK, Hamatake RK, and Hong Z

Expert opinion on investigational drugs 13(3):289-93, 2004 Mar - Who cited this? | PubMed ID: 15013947 | Fulltext

The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication.

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Stracker TH, Cassell GD, Ward P, Loo YM, van Breukelen B, Carrington-Lawrence SD, Hamatake RK, van der Vliet PC, Weller SK, Melendy T, and Weitzman MD

Journal of virology 78(1):441-53, 2004 Jan - Who cited this? | PubMed ID: 14671124 | Fulltext

Agents in clinical development for the treatment of chronic hepatitis B.

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Raney AK, Hamatake RK, and Hong Z

Expert opinion on investigational drugs 12(8):1281-95, 2003 Aug - Who cited this? | PubMed ID: 12882617 | Fulltext

De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus.

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Luo G, Hamatake RK, Mathis DM, Racela J, Rigat KL, Lemm J, and Colonno RJ

Journal of virology 74(2):851-63, 2000 Jan - Who cited this? | PubMed ID: 10623748 | Fulltext

In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir.

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Seifer M, Hamatake RK, Colonno RJ, and Standring DN

Antimicrobial agents and chemotherapy 42(12):3200-8, 1998 Dec - Who cited this? | PubMed ID: 9835515 | Fulltext

A functional interaction of ICP8, the herpes simplex virus single-stranded DNA-binding protein, and the helicase-primase complex that is dependent on the presence of the UL8 subunit.

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Hamatake RK, Bifano M, Hurlburt WW, and Tenney DJ

The Journal of general virology 78 ( Pt 4):857-65, 1997 Apr - Who cited this? | PubMed ID: 9129659 | Fulltext

Characterization of monoclonal antibodies recognizing amino- and carboxy-terminal epitopes of the herpes simplex virus UL42 protein.

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Sheaffer AK, Hurlburt WW, Stevens JT, Bifano M, Hamatake RK, Colonno RJ, and Tenney DJ

Virus research 38(2-3):305-14, 1995 Oct - Who cited this? | PubMed ID: 8578868 | Fulltext

Sequence-dependent primer synthesis by the herpes simplex virus helicase-primase complex.

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Tenney DJ, Sheaffer AK, Hurlburt WW, Bifano M, and Hamatake RK

The Journal of biological chemistry 270(16):9129-36, 1995 Apr 21 - Who cited this? | PubMed ID: 7721827 | Fulltext

The UL8 component of the herpes simplex virus helicase-primase complex stimulates primer synthesis by a subassembly of the UL5 and UL52 components.

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Tenney DJ, Hurlburt WW, Micheletti PA, Bifano M, and Hamatake RK

The Journal of biological chemistry 269(7):5030-5, 1994 Feb 18 - Who cited this? | PubMed ID: 8106478 | Fulltext

The herpes simplex virus type 1 DNA polymerase accessory protein, UL42, contains a functional protease-resistant domain.

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Hamatake RK, Bifano M, Tenney DJ, Hurlburt WW, and Cordingley MG

The Journal of general virology 74 ( Pt 10):2181-9, 1993 Oct - Who cited this? | PubMed ID: 8409941 | Fulltext

Deletions of the carboxy terminus of herpes simplex virus type 1 UL42 define a conserved amino-terminal functional domain.

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Tenney DJ, Hurlburt WW, Bifano M, Stevens JT, Micheletti PA, Hamatake RK, and Cordingley MG

Journal of virology 67(4):1959-66, 1993 Apr - Who cited this? | PubMed ID: 8383221 | Fulltext

Mutations in the C terminus of herpes simplex virus type 1 DNA polymerase can affect binding and stimulation by its accessory protein UL42 without affecting basal polymerase activity.

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Tenney DJ, Micheletti PA, Stevens JT, Hamatake RK, Matthews JT, Sanchez AR, Hurlburt WW, Bifano M, and Cordingley MG

Journal of virology 67(1):543-7, 1993 Jan - Who cited this? | PubMed ID: 8380091 | Fulltext

Cloning DPB3, the gene encoding the third subunit of DNA polymerase II of Saccharomyces cerevisiae.

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Araki H, Hamatake RK, Morrison A, Johnson AL, Johnston LH, and Sugino A

Nucleic acids research 19(18):4867-72, 1991 Sep 25 - Who cited this? | PubMed ID: 1923754 | Fulltext

DPB2, the gene encoding DNA polymerase II subunit B, is required for chromosome replication in Saccharomyces cerevisiae.

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Araki H, Hamatake RK, Johnston LH, and Sugino A

Proceedings of the National Academy of Sciences of the United States of America 88(11):4601-5, 1991 Jun 1 - Who cited this? | PubMed ID: 2052544 | Fulltext

Cloning and characterization of DST2, the gene for DNA strand transfer protein beta from Saccharomyces cerevisiae.

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Dykstra CC, Kitada K, Clark AB, Hamatake RK, and Sugino A

Molecular and cellular biology 11(5):2583-92, 1991 May - Who cited this? | PubMed ID: 1850100 | Fulltext

A third essential DNA polymerase in S. cerevisiae.

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Morrison A, Araki H, Clark AB, Hamatake RK, and Sugino A

Cell 62(6):1143-51, 1990 Sep 21 - Who cited this? | PubMed ID: 2169349 | Fulltext

DNA strand transfer protein beta from yeast mitotic cells differs from strand transfer protein alpha from meiotic cells.

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Dykstra CC, Hamatake RK, and Sugino A

The Journal of biological chemistry 265(19):10968-73, 1990 Jul 5 - Who cited this? | PubMed ID: 2141605 | Fulltext

Purification and characterization of DNA polymerase II from the yeast Saccharomyces cerevisiae. Identification of the catalytic core and a possible holoenzyme form of the enzyme.

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Hamatake RK, Hasegawa H, Clark AB, Bebenek K, Kunkel TA, and Sugino A

The Journal of biological chemistry 265(7):4072-83, 1990 Mar 5 - Who cited this? | PubMed ID: 2406268 | Fulltext

Effect of accessory proteins on the fidelity of DNA synthesis by eukaryotic replicative polymerases.

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Roberts JD, Hamatake RK, Fitzgerald MS, Sugino A, and Kunkel TA

Progress in clinical and biological research 340A:91-100, 1990 - Who cited this? | PubMed ID: 2167484 | Fulltext

Fidelity of DNA polymerase I and the DNA polymerase I-DNA primase complex from Saccharomyces cerevisiae.

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Kunkel TA, Hamatake RK, Motto-Fox J, Fitzgerald MP, and Sugino A

Molecular and cellular biology 9(10):4447-58, 1989 Oct - Who cited this? | PubMed ID: 2555694 | Fulltext

Presynapsis and synapsis of DNA promoted by the STP alpha and single-stranded DNA-binding proteins from Saccharomyces cerevisiae.

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Hamatake RK, Dykstra CC, and Sugino A

The Journal of biological chemistry 264(22):13336-42, 1989 Aug 5 - Who cited this? | PubMed ID: 2546954 | Fulltext

The J gene of phi X174: isolation and characterization of a J gene mutant.

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Hamatake RK, Buckley KJ, and Hayashi M

Molecular & general genetics : MGG 211(1):72-7, 1988 Jan - Who cited this? | PubMed ID: 2963945 | Fulltext

The J gene of bacteriophage phi X174: in vitro analysis of J protein function.

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Hamatake RK, Aoyama A, and Hayashi M

Journal of virology 54(2):345-50, 1985 May - Who cited this? | PubMed ID: 3157804 | Fulltext

In vitro synthesis of bacteriophage phi X174 by purified components.

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Aoyama A, Hamatake RK, and Hayashi M

Proceedings of the National Academy of Sciences of the United States of America 80(14):4195-9, 1983 Jul - Who cited this? | PubMed ID: 6224217 | Fulltext

Purification of phi X174 gene C protein.

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Aoyama A, Hamatake RK, Mukai R, and Hayashi M

The Journal of biological chemistry 258(9):5798-803, 1983 May 10 - Who cited this? | PubMed ID: 6222055 | Fulltext

Morphogenesis of phi X174: in vitro synthesis of infectious phage from purified viral components.

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Aoyama A, Hamatake RK, and Hayashi M

Proceedings of the National Academy of Sciences of the United States of America 78(12):7285-9, 1981 Dec - Who cited this? | PubMed ID: 6461002 | Fulltext

Role of DNA gyrase subunits in synthesis of bacteriophage phi X174 viral DNA.

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Hamatake RK, Mukai R, and Hayashi M

Proceedings of the National Academy of Sciences of the United States of America 78(3):1532-6, 1981 Mar - Who cited this? | PubMed ID: 6262812 | Fulltext

Isolation and identification of bacteriophage phi X174 prohead.

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Mukai R, Hamatake RK, and Hayashi M

Proceedings of the National Academy of Sciences of the United States of America 76(10):4877-81, 1979 Oct - Who cited this? | PubMed ID: 159449 | Fulltext

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