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Papers authored by Haines DC

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Paraoxonase 2 is down-regulated by the Pseudomonas aeruginosa quorumsensing signal N-(3-oxododecanoyl)-L-homoserine lactone and attenuates oxidative stress induced by pyocyanin.

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Horke S, Witte I, Altenhöfer S, Wilgenbus P, Goldeck M, Förstermann U, Xiao J, Kramer GL, Haines DC, Chowdhary PK, Haley RW, and Teiber JF

The Biochemical journal 426(1):73-83, 2010 Mar 1 - Who cited this? | PubMed ID: 19925453 | Fulltext

Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.

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Hasumi Y, Baba M, Ajima R, Hasumi H, Valera VA, Klein ME, Haines DC, Merino MJ, Hong SB, Yamaguchi TP, Schmidt LS, and Linehan WM

Proceedings of the National Academy of Sciences of the United States of America 106(44):18722-7, 2009 Nov 3 - Who cited this? | PubMed ID: 19850877 | Fulltext

Urothelial overexpression of insulin-like growth factor-1 increases susceptibility to p-cresidine-induced bladder carcinogenesis in transgenic mice.

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Hursting SD, Perkins SN, Lavigne JA, Beltran L, Haines DC, Hill HL, Alvord WG, Barrett JC, and DiGiovanni J

Molecular carcinogenesis 48(8):671-7, 2009 Aug - Who cited this? | PubMed ID: 19415693 | Fulltext

Exercise effects on tumorigenesis in a p53-deficient mouse model of breast cancer.

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Colbert LH, Westerlind KC, Perkins SN, Haines DC, Berrigan D, Donehower LA, Fuchs-Young R, and Hursting SD

Medicine and science in sports and exercise 41(8):1597-605, 2009 Aug - Who cited this? | PubMed ID: 19568200 | Fulltext

Host-derived tumor endothelial marker 8 promotes the growth of melanoma.

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Cullen M, Seaman S, Chaudhary A, Yang MY, Hilton MB, Logsdon D, Haines DC, Tessarollo L, and St Croix B

Cancer research 69(15):6021-6, 2009 Aug 1 - Who cited this? | PubMed ID: 19622764 | Fulltext

Loss of rad51c leads to embryonic lethality and modulation of Trp53-dependent tumorigenesis in mice.

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Kuznetsov SG, Haines DC, Martin BK, and Sharan SK

Cancer research 69(3):863-72, 2009 Feb 1 - Who cited this? | PubMed ID: 19155299 | Fulltext

Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications.

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Philip S, Swaminathan S, Kuznetsov SG, Kanugula S, Biswas K, Chang S, Loktionova NA, Haines DC, Kaldis P, Pegg AE, and Sharan SK

Cancer research 68(23):9973-81, 2008 Dec 1 - Who cited this? | PubMed ID: 19047179 | Fulltext

A single mutation in P450BM-3 enhances acyl homoserine lactone: Acyl homoserine substrate binding selectivity nearly 250-fold.

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Chowdhary PK, Stewart L, Lopez C, and Haines DC

Journal of biotechnology 135(4):374-6, 2008 Jul 31 - Who cited this? | PubMed ID: 18586345 | Fulltext

Dominant role of paraoxonases in inactivation of the Pseudomonas aeruginosa quorum-sensing signal N-(3-oxododecanoyl)-L-homoserine lactone.

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Teiber JF, Horke S, Haines DC, Chowdhary PK, Xiao J, Kramer GL, Haley RW, and Draganov DI

Infection and immunity 76(6):2512, 2008 Jun - Who cited this? | PubMed ID: 18347034 | Fulltext

Crystal Structure of Inhibitor-Bound P450BM-3 Reveals Open Conformation of Substrate Access Channel(,).

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Haines DC, Chen B, Tomchick DR, Bondlela M, Hegde A, Machius M, and Peterson JA

Biochemistry 47(12):3662-70, 2008 Mar 25 - Who cited this? | PubMed ID: 18298086 | Fulltext

Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.

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Baba M, Furihata M, Hong SB, Tessarollo L, Haines DC, Southon E, Patel V, Igarashi P, Alvord WG, Leighty R, Yao M, Bernardo M, Ileva L, Choyke P, Warren MB, Zbar B,

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Journal of the National Cancer Institute 100(2):140, 2008 Jan 16 - Who cited this? | PubMed ID: 18182616 | Fulltext

Bacillus megaterium CYP102A1 oxidation of acyl homoserine lactones and acyl homoserines.

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Chowdhary PK, Keshavan N, Nguyen HQ, Peterson JA, González JE, and Haines DC

Biochemistry 46(50):14429-37, 2007 Dec 18 - Who cited this? | PubMed ID: 18020460 | Fulltext

Interactions of substrates at the surface of p450s can greatly enhance substrate potency(,).

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Hegde A, Haines DC, Bondlela M, Chen B, Schaffer N, Tomchick DR, Machius M, Nguyen H, Chowdhary PK, Stewart L, Lopez C, and Peterson JA

Biochemistry 46(49):14010-7, 2007 Dec 11 - Who cited this? | PubMed ID: 18004886 | Fulltext

Cloning, expression and characterization of a fast self-sufficient P450: CYP102A5 from Bacillus cereus.

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Chowdhary PK, Alemseghed M, and Haines DC

Archives of biochemistry and biophysics 468(1):32-43, 2007 Dec 1 - Who cited this? | PubMed ID: 17945181 | Fulltext

Obligatory intermolecular electron-transfer from FAD to FMN in dimeric P450BM-3.

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Kitazume T, Haines DC, Estabrook RW, Chen B, and Peterson JA

Biochemistry 46(42):11892-901, 2007 Oct 23 - Who cited this? | PubMed ID: 17902705 | Fulltext

Itch genetically interacts with Notch1 in a mouse autoimmune disease model.

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Matesic LE, Haines DC, Copeland NG, and Jenkins NA

Human molecular genetics 15(24):3485, 2006 Dec 15 - Who cited this? | PubMed ID: 17095521 | Fulltext

A role for the strained phenylalanine ring rotation induced by substrate binding to cytochrome CYP102A1.

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Haines DC

Protein and peptide letters 13(10):977, 2006 - Who cited this? | PubMed ID: 17168818 | Fulltext

L-Canavanine made by Medicago sativa interferes with quorum sensing in Sinorhizobium meliloti.

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Keshavan ND, Chowdhary PK, Haines DC, and González JE

Journal of bacteriology 187(24):8427, 2005 Dec - Who cited this? | PubMed ID: 16321947 | Fulltext

Increased tumorigenicity and sensitivity to ionizing radiation upon loss of chromosomal protein HMGN1.

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Birger Y, Catez F, Furusawa T, Lim JH, Prymakowska-Bosak M, West KL, Postnikov YV, Haines DC, and Bustin M

Cancer research 65(15):6711, 2005 Aug 1 - Who cited this? | PubMed ID: 16061652 | Fulltext

Modulation of zinc- and cobalt-binding affinities through changes in the stability of the zinc ribbon protein L36.

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Kou W, Kolla HS, Ortiz-Acevedo A, Haines DC, Junker M, and Dieckmann GR

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 10(2):167-80, 2005 Mar - Who cited this? | PubMed ID: 15747135 | Fulltext

Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium.

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Nikitin AY, Alcaraz A, Anver MR, Bronson RT, Cardiff RD, Dixon D, Fraire AE, Gabrielson EW, Gunning WT, Haines DC, Kaufman MH, Linnoila RI, Maronpot RR, Rabson AS, Reddick RL, Rehm S,

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Cancer research 64(7):2307, 2004 Apr 1 - Who cited this? | PubMed ID: 15059877 | Fulltext

Exercise and intestinal polyp development in APCMin mice.

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Colbert LH, Mai V, Perkins SN, Berrigan D, Lavigne JA, Wimbrow HH, Alvord WG, Haines DC, Srinivas P, and Hursting SD

Medicine and science in sports and exercise 35(10):1662-9, 2003 Oct - Who cited this? | PubMed ID: 14523302 | Fulltext

Calorie restriction and diet composition modulate spontaneous intestinal tumorigenesis in Apc(Min) mice through different mechanisms.

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Mai V, Colbert LH, Berrigan D, Perkins SN, Pfeiffer R, Lavigne JA, Lanza E, Haines DC, Schatzkin A, and Hursting SD

Cancer research 63(8):1752-5, 2003 Apr 15 - Who cited this? | PubMed ID: 12702556 | Fulltext

pH-induced alteration and oxidative destruction of heme in purified chromaffin granule cytochrome b(561): implications for the oxidative stress in catecholaminergic neurons.

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Wanduragala S, Wimalasena DS, Haines DC, Kahol PK, and Wimalasena K

Biochemistry 42(12):3617-26, 2003 Apr 1 - Who cited this? | PubMed ID: 12653566 | Fulltext

Plausible molecular mechanism for activation by fumarate and electron transfer of the dopamine beta-mono-oxygenase reaction.

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Wimalasena DS, Jayatillake SP, Haines DC, and Wimalasena K

The Biochemical journal 367(Pt 1):77-85, 2002 Oct 1 - Who cited this? | PubMed ID: 12038965 | Fulltext

Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice.

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Kogan SC, Ward JM, Anver MR, Berman JJ, Brayton C, Cardiff RD, Carter JS, de Coronado S, Downing JR, Fredrickson TN, Haines DC, Harris AW, Harris NL, Hiai H, Jaffe ES, MacLennan IC,

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Blood 100(1):238-45, 2002 Jul 1 - Who cited this? | PubMed ID: 12070033 | Fulltext

Bethesda proposals for classification of lymphoid neoplasms in mice.

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Morse HC, Anver MR, Fredrickson TN, Haines DC, Harris AW, Harris NL, Jaffe ES, Kogan SC, MacLennan IC, Pattengale PK, Ward JM, and Hematopathology subcommittee of the Mouse Models of Human Cancers Consortium

Blood 100(1):246-58, 2002 Jul 1 - Who cited this? | PubMed ID: 12070034 | Fulltext

Adult-onset calorie restriction and fasting delay spontaneous tumorigenesis in p53-deficient mice.

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Berrigan D, Perkins SN, Haines DC, and Hursting SD

Carcinogenesis 23(5):817, 2002 May - Who cited this? | PubMed ID: 12016155 | Fulltext

Pivotal role of water in the mechanism of P450BM-3.

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Haines DC, Tomchick DR, Machius M, and Peterson JA

Biochemistry 40(45):13456-65, 2001 Nov 13 - Who cited this? | PubMed ID: 11695892 | Fulltext

Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis.

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Im YH, Kim HT, Kim IY, Factor VM, Hahm KB, Anzano M, Jang JJ, Flanders K, Haines DC, Thorgeirsson SS, Sizeland A, and Kim SJ

Cancer research 61(18):6665-8, 2001 Sep 15 - Who cited this? | PubMed ID: 11559531 | Fulltext

Dimethylbenzanthracene carcinogenesis in Gadd45a-null mice is associated with decreased DNA repair and increased mutation frequency.

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Hollander MC, Kovalsky O, Salvador JM, Kim KE, Patterson AD, Haines DC, and Fornace AJ

Cancer research 61(6):2487-91, 2001 Mar 15 - Who cited this? | PubMed ID: 11289119 | Fulltext

Hyalinosis and Ym1/Ym2 gene expression in the stomach and respiratory tract of 129S4/SvJae and wild-type and CYP1A2-null B6, 129 mice.

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Ward JM, Yoon M, Anver MR, Haines DC, Kudo G, Gonzalez FJ, and Kimura S

The American journal of pathology 158(1):323-32, 2001 Jan - Who cited this? | PubMed ID: 11141507 | Fulltext

Pathology of aging B6;129 mice.

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Haines DC, Chattopadhyay S, and Ward JM

Toxicologic pathology 29(6):653-61, 2001 - Who cited this? | PubMed ID: 11794381 | Fulltext

The FMN-binding domain of cytochrome P450BM-3: resolution, reconstitution, and flavin analogue substitution.

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Haines DC, Sevrioukova IF, and Peterson JA

Biochemistry 39(31):9419-29, 2000 Aug 8 - Who cited this? | PubMed ID: 10924137 | Fulltext

Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice.

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Diwan BA, Riggs CW, Logsdon D, Haines DC, Olivero OA, Rice JM, Yuspa SH, Poirier MC, and Anderson LM

Toxicology and applied pharmacology 161(1):82-99, 1999 Nov 15 - Who cited this? | PubMed ID: 10558926 | Fulltext

Preconception urethane or chromium(III) treatment of male mice: multiple neoplastic and non-neoplastic changes in offspring.

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Yu W, Sipowicz MA, Haines DC, Birely L, Diwan BA, Riggs CW, Kasprzak KS, and Anderson LM

Toxicology and applied pharmacology 158(2):161-76, 1999 Jul 15 - Who cited this? | PubMed ID: 10406931 | Fulltext

Skin tumorigenesis and Ki-ras and Ha-ras mutations in tumors from adult mice exposed in utero to 3'-azido-2',3'-dideoxythymidine.

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Zhang Z, Diwan BA, Anderson LM, Logsdon D, Olivero OA, Haines DC, Rice JM, Yuspa SH, and Poirier MC

Molecular carcinogenesis 23(1):45-51, 1998 Sep - Who cited this? | PubMed ID: 9766437 | Fulltext

Calorie restriction reduces ulcerative dermatitis and infection-related mortality in p53-deficient and wild-type mice.

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Perkins SN, Hursting SD, Phang JM, and Haines DC

The Journal of investigative dermatology 111(2):292-6, 1998 Aug - Who cited this? | PubMed ID: 9699732 | Fulltext

Inflammatory large bowel disease in immunodeficient rats naturally and experimentally infected with Helicobacter bilis.

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Haines DC, Gorelick PL, Battles JK, Pike KM, Anderson RJ, Fox JG, Taylor NS, Shen Z, Dewhirst FE, Anver MR, and Ward JM

Veterinary pathology 35(3):202, 1998 May - Who cited this? | PubMed ID: 9598583 | Fulltext

Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene.

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Böttinger EP, Jakubczak JL, Haines DC, Bagnall K, and Wakefield LM

Cancer research 57(24):5564-70, 1997 Dec 15 - Who cited this? | PubMed ID: 9407968 | Fulltext

Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys.

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Olivero OA, Anderson LM, Diwan BA, Haines DC, Harbaugh SW, Moskal TJ, Jones AB, Rice JM, Riggs CW, Logsdon D, Yuspa SH, and Poirier MC

Journal of the National Cancer Institute 89(21):1602-8, 1997 Nov 5 - Who cited this? | PubMed ID: 9362158 | Fulltext

Calorie restriction induces a p53-independent delay of spontaneous carcinogenesis in p53-deficient and wild-type mice.

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Hursting SD, Perkins SN, Brown CC, Haines DC, and Phang JM

Cancer research 57(14):2843-6, 1997 Jul 15 - Who cited this? | PubMed ID: 9230186 | Fulltext

Chiral multisubstrate inhibitors of dopamine beta-monooxygenase: evidence for dual modes of interaction.

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Wimalasena K, Wimalasena DS, Dharmasena S, Haines DC, and Alliston KR

Biochemistry 36(23):7144-53, 1997 Jun 10 - Who cited this? | PubMed ID: 9188714 | Fulltext

Chemoprevention of spontaneous tumorigenesis in nullizygous p53-deficient mice by dehydroepiandrosterone and its analog 16alpha-fluoro-5-androsten-17-one.

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Perkins SN, Hursting SD, Haines DC, James SJ, Miller BJ, and Phang JM

Carcinogenesis 18(5):989-94, 1997 May - Who cited this? | PubMed ID: 9163685 | Fulltext

A general progress curve method for the kinetic analysis of suicide enzyme inhibitors.

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Wimalasena K and Haines DC

Analytical biochemistry 234(2):175-82, 1996 Feb 15 - Who cited this? | PubMed ID: 8714595 | Fulltext

Inflammatory large bowel disease in immunodeficient mice naturally infected with Helicobacter hepaticus.

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Ward JM, Anver MR, Haines DC, Melhorn JM, Gorelick P, Yan L, and Fox JG

Laboratory animal science 46(1):15-20, 1996 Feb - Who cited this? | PubMed ID: 8699813 | Fulltext

Chemoprevention of spontaneous tumorigenesis in p53-knockout mice.

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Hursting SD, Perkins SN, Haines DC, Ward JM, and Phang JM

Cancer research 55(18):3949-53, 1995 Sep 15 - Who cited this? | PubMed ID: 7664260 | Fulltext

Use of antibiotics to prevent hepatitis and typhlitis in male scid mice spontaneously infected with Helicobacter hepaticus.

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Russell RJ, Haines DC, Anver MR, Battles JK, Gorelick PL, Blumenauer LL, Gonda MA, and Ward JM

Laboratory animal science 45(4):373-8, 1995 Aug - Who cited this? | PubMed ID: 7474875 | Fulltext

Chronic active hepatitis in mice caused by Helicobacter hepaticus.

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Ward JM, Anver MR, Haines DC, and Benveniste RE

The American journal of pathology 145(4):959-68, 1994 Oct - Who cited this? | PubMed ID: 7943185 | Fulltext

Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species.

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Ward JM, Fox JG, Anver MR, Haines DC, George CV, Collins MJ, Gorelick PL, Nagashima K, Gonda MA, and Gilden RV

Journal of the National Cancer Institute 86(16):1222-7, 1994 Aug 17 - Who cited this? | PubMed ID: 8040890 | Fulltext

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