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Papers authored by Groop LC

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GAD antibody positivity predicts type 2 diabetes in an adult population.

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Lundgren VM, Isomaa B, Lyssenko V, Laurila E, Korhonen P, Groop LC, Tuomi T, and Botnia Study Group

Diabetes 59(2):416-22, 2010 Feb - Who cited this? | PubMed ID: 19864397 | Fulltext

Erratum to: Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes.

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Pulizzi N, Lyssenko V, Jonsson A, Osmond C, Laakso M, Kajantie E, Barker DJ, Groop LC, and Eriksson JG

Diabetologia 52(12):2671-2, 2009 Dec - Who cited this? | PubMed ID: 19784616 | Fulltext

Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes.

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Pulizzi N, Lyssenko V, Jonsson A, Osmond C, Laakso M, Kajantie E, Barker DJ, Groop LC, and Eriksson JG

Diabetologia 52(5):825-9, 2009 May - Who cited this? | PubMed ID: 19225753 | Fulltext

Variants in MTNR1B influence fasting glucose levels.

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Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M,

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Nature genetics 41(1):77-81, 2009 Jan - Who cited this? | PubMed ID: 19060907 | Fulltext

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

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Willer CJ, Speliotes EK, Loos RJ, Li S, Lindgren CM, Heid IM, Berndt SI, Elliott AL, Jackson AU, Lamina C, Lettre G, Lim N, Lyon HN, McCarroll SA, Papadakis K, Qi L,

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Nature genetics 41(1):25-34, 2009 Jan - Who cited this? | PubMed ID: 19079261 | Fulltext

Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus.

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Parikh H, Lyssenko V, and Groop LC

BMC medical genomics 2(1):72, 2009 - Who cited this? | PubMed ID: 20043853 | Fulltext

Common variants in the TCF7L2 gene help to differentiate autoimmune from non-autoimmune diabetes in young (15-34 years) but not in middle-aged (40-59 years) diabetic patients.

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Bakhtadze E, Cervin C, Lindholm E, Borg H, Nilsson P, Arnqvist HJ, Bolinder J, Eriksson JW, Gudbjörnsdottir S, Nyström L, Agardh CD, Landin-Olsson M, Sundkvist G, and Groop LC

Diabetologia, 2008 Oct 7 - Who cited this? | PubMed ID: 18839133 | Fulltext

Molecular correlates for maximal oxygen uptake and type 1 fibers.

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Parikh H, Nilsson E, Ling C, Poulsen P, Almgren P, Nittby H, Eriksson KF, Vaag A, and Groop LC

American journal of physiology. Endocrinology and metabolism 294(6), 2008 Jun - Who cited this? | PubMed ID: 18445752 | Fulltext

Identification of ten loci associated with height highlights new biological pathways in human growth.

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Lettre G, Jackson AU, Gieger C, Schumacher FR, Berndt SI, Sanna S, Eyheramendy S, Voight BF, Butler JL, Guiducci C, Illig T, Hackett R, Heid IM, Jacobs KB, Lyssenko V, Uda M,

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Nature genetics 40(5):584, 2008 May - Who cited this? | PubMed ID: 18391950 | Fulltext

A common variant of HMGA2 is associated with adult and childhood height in the general population.

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Weedon MN, Lettre G, Freathy RM, Lindgren CM, Voight BF, Perry JR, Elliott KS, Hackett R, Guiducci C, Shields B, Zeggini E, Lango H, Lyssenko V, Timpson NJ, Burtt NP, Rayner NW,

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Nature genetics 39(10):1245-50, 2007 Oct - Who cited this? | PubMed ID: 17767157 | Fulltext

TXNIP regulates peripheral glucose metabolism in humans.

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Parikh H, Carlsson E, Chutkow WA, Johansson LE, Storgaard H, Poulsen P, Saxena R, Ladd C, Schulze PC, Mazzini MJ, Jensen CB, Krook A, Björnholm M, Tornqvist H, Zierath JR, Ridderstråle M,

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PLoS medicine 4(5), 2007 May - Who cited this? | PubMed ID: 17472435 | Fulltext

Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men.

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Campbell CD, Lyon HN, Nemesh J, Drake JA, Tuomi T, Gaudet D, Zhu X, Cooper RS, Ardlie KG, Groop LC, and Hirschhorn JN

Diabetes 56(5):1460, 2007 May - Who cited this? | PubMed ID: 17325259 | Fulltext

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals.

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Saxena R, Gianniny L, Burtt NP, Lyssenko V, Giuducci C, Sjögren M, Florez JC, Almgren P, Isomaa B, Orho-Melander M, Lindblad U, Daly MJ, Tuomi T, Hirschhorn JN, Ardlie KG, Groop LC,

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Diabetes 55(10):2890, 2006 Oct - Who cited this? | PubMed ID: 17003358 | Fulltext

HLA-DQB1 genotypes, islet antibodies and beta cell function in the classification of recent-onset diabetes among young adults in the nationwide Diabetes Incidence Study in Sweden.

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Bakhtadze E, Borg H, Stenström G, Fernlund P, Arnqvist HJ, Ekbom-Schnell A, Bolinder J, Eriksson JW, Gudbjörnsdottir S, Nyström L, Groop LC, and Sundkvist G

Diabetologia 49(8):1785-94, 2006 Aug - Who cited this? | PubMed ID: 16783473 | Fulltext

A dietary exchange of common bread for tailored bread of low glycaemic index and rich in dietary fibre improved insulin economy in young women with impaired glucose tolerance.

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Ostman EM, Frid AH, Groop LC, and Björck IM

European journal of clinical nutrition 60(3):334-41, 2006 Mar - Who cited this? | PubMed ID: 16234828 | Fulltext

Improved prandial glucose control with lower risk of hypoglycemia with nateglinide than with glibenclamide in patients with maturity-onset diabetes of the young type 3.

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Tuomi T, Honkanen EH, Isomaa B, Sarelin L, and Groop LC

Diabetes care 29(2):189-94, 2006 Feb - Who cited this? | PubMed ID: 16443858 | Fulltext

Demonstrating stratification in a European American population.

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Campbell CD, Ogburn EL, Lunetta KL, Lyon HN, Freedman ML, Groop LC, Altshuler D, Ardlie KG, and Hirschhorn JN

Nature genetics 37(8):868-72, 2005 Aug - Who cited this? | PubMed ID: 16041375 | Fulltext

Effects of morning cortisol replacement on glucose and lipid metabolism in GH-treated subjects.

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Segerlantz M, Bramnert M, Thomasson R, Manhem P, Laurila E, and Groop LC

European journal of endocrinology / European Federation of Endocrine Societies 151(6):701-7, 2004 Dec - Who cited this? | PubMed ID: 15588236 | Fulltext

Inhibition of lipolysis during acute GH exposure increases insulin sensitivity in previously untreated GH-deficient adults.

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Segerlantz M, Bramnert M, Manhem P, Laurila E, and Groop LC

European journal of endocrinology / European Federation of Endocrine Societies 149(6):511, 2003 Dec - Who cited this? | PubMed ID: 14640991 | Fulltext

The insertion/deletion variation in the alpha2B-adrenoceptor does not seem to modify the risk for acute myocardial infarction, but may modify the risk for hypertension in sib-pairs from families with type 2 diabetes.

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Snapir A, Scheinin M, Groop LC, and Orho-Melander M

Cardiovascular diabetology 2:15, 2003 Nov 24 - Who cited this? | PubMed ID: 14633283 | Fulltext

A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes.

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Demenais F, Kanninen T, Lindgren CM, Wiltshire S, Gaget S, Dandrieux C, Almgren P, Sjögren M, Hattersley A, Dina C, Tuomi T, McCarthy MI, Froguel P, and Groop LC

Human molecular genetics 12(15):1865-73, 2003 Aug 1 - Who cited this? | PubMed ID: 12874106 | Fulltext

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes.

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Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P,

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Nature genetics 34(3):267, 2003 Jul - Who cited this? | PubMed ID: 12808457 | Fulltext

A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.

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Frayling TM, Lindgren CM, Chevre JC, Menzel S, Wishart M, Benmezroua Y, Brown A, Evans JC, Rao PS, Dina C, Lecoeur C, Kanninen T, Almgren P, Bulman MP, Wang Y, Mills J,

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Diabetes 52(3):872-81, 2003 Mar - Who cited this? | PubMed ID: 12606533 | Fulltext

Polymorphisms of the HDL receptor gene associated with HDL cholesterol levels in diabetic kindred from three populations.

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McCarthy JJ, Lewitzky S, Reeves C, Permutt A, Glaser B, Groop LC, Lehner T, and Meyer JM

Human heredity 55(4):163-70, 2003 - Who cited this? | PubMed ID: 14566094 | Fulltext

Contribution of known and unknown susceptibility genes to early-onset diabetes in scandinavia: evidence for heterogeneity.

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Lindgren CM, Widén E, Tuomi T, Li H, Almgren P, Kanninen T, Melander O, Weng J, Lehto M, and Groop LC

Diabetes 51(5):1609-17, 2002 May - Who cited this? | PubMed ID: 11978663 | Fulltext

5' flanking variants of resistin are associated with obesity.

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Engert JC, Vohl MC, Williams SM, Lepage P, Loredo-Osti JC, Faith J, Doré C, Renaud Y, Burtt NP, Villeneuve A, Hirschhorn JN, Altshuler D, Groop LC, Després JP, Gaudet D, and Hudson TJ

Diabetes 51(5):1629-34, 2002 May - Who cited this? | PubMed ID: 11978666 | Fulltext

Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study.

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Lindgren CM, Mahtani MM, Widén E, McCarthy MI, Daly MJ, Kirby A, Reeve MP, Kruglyak L, Parker A, Meyer J, Almgren P, Lehto M, Kanninen T, Tuomi T, Groop LC, and Lander ES

American journal of human genetics 70(2):509-16, 2002 Feb - Who cited this? | PubMed ID: 11791216 | Fulltext

Screening for MODY mutations, GAD antibodies, and type 1 diabetes--associated HLA genotypes in women with gestational diabetes mellitus.

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Weng J, Ekelund M, Lehto M, Li H, Ekberg G, Frid A, Aberg A, Groop LC, and Berntorp K

Diabetes care 25(1):68-71, 2002 Jan - Who cited this? | PubMed ID: 11772903 | Fulltext

Inhibition of the rise in FFA by Acipimox partially prevents GH-induced insulin resistance in GH-deficient adults.

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Segerlantz M, Bramnert M, Manhem P, Laurila E, and Groop LC

The Journal of clinical endocrinology and metabolism 86(12):5813-8, 2001 Dec - Who cited this? | PubMed ID: 11739444 | Fulltext

An automated fluorescent single strand conformation polymorphism technique for high throughput mutation screening.

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Weng J, Lehto M, Berglund A, and Groop LC

Chinese medical journal 114(11):1147-50, 2001 Nov - Who cited this? | PubMed ID: 11729508 | Fulltext

Characterization of the annexin I gene and evaluation of its role in type 2 diabetes.

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Lindgren CM, Nilsson A, Orho-Melander M, Almgren P, and Groop LC

Diabetes 50(10):2402-5, 2001 Oct - Who cited this? | PubMed ID: 11574426 | Fulltext

Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height.

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Hirschhorn JN, Lindgren CM, Daly MJ, Kirby A, Schaffner SF, Burtt NP, Altshuler D, Parker A, Rioux JD, Platko J, Gaudet D, Hudson TJ, Groop LC, and Lander ES

American journal of human genetics 69(1):106-16, 2001 Jul - Who cited this? | PubMed ID: 11410839 | Fulltext

Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)--adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes.

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Carlsson M, Orho-Melander M, Hedenbro J, and Groop LC

Diabetologia 44(5):629-36, 2001 May - Who cited this? | PubMed ID: 11380082 | Fulltext

Assessment of beta-cell function during the oral glucose tolerance test by a minimal model of insulin secretion.

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Cretti A, Lehtovirta M, Bonora E, Brunato B, Zenti MG, Tosi F, Caputo M, Caruso B, Groop LC, Muggeo M, and Bonadonna RC

European journal of clinical investigation 31(5):405-16, 2001 May - Who cited this? | PubMed ID: 11380592 | Fulltext

A gene conferring susceptibility to type 2 diabetes in conjunction with obesity is located on chromosome 18p11.

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Parker A, Meyer J, Lewitzky S, Rennich JS, Chan G, Thomas JD, Orho-Melander M, Lehtovirta M, Forsblom C, Hyrkkö A, Carlsson M, Lindgren C, and Groop LC

Diabetes 50(3):675-80, 2001 Mar - Who cited this? | PubMed ID: 11246890 | Fulltext

Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations.

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Weng J, Macfarlane WM, Lehto M, Gu HF, Shepherd LM, Ivarsson SA, Wibell L, Smith T, and Groop LC

Diabetologia 44(2):249-58, 2001 Feb - Who cited this? | PubMed ID: 11270685 | Fulltext

Hypothalamic-pituitary-adrenal response to different tests in type 1 diabetes mellitus.

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Almqvist EG, Groop LC, and Manhem PJ

Scandinavian journal of clinical and laboratory investigation 61(7):557-65, 2001 - Who cited this? | PubMed ID: 11763414 | Fulltext

Characterization, chromosomal localization, and expression during hematopoietic differentiation of the gene encoding Arl6ip, ADP-ribosylation-like factor-6 interacting protein (ARL6).

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Pettersson M, Bessonova M, Gu HF, Groop LC, and Jönsson JI

Genomics 68(3):351-4, 2000 Sep 15 - Who cited this? | PubMed ID: 10995579 | Fulltext

Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis.

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Gu HF, Almgren P, Lindholm E, Frittitta L, Pizzuti A, Trischitta V, and Groop LC

Diabetes 49(9):1601-3, 2000 Sep - Who cited this? | PubMed ID: 10969847 | Fulltext

The T 54 allele of the intestinal fatty acid-binding protein 2 is associated with a parental history of stroke.

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Carlsson M, Orho-Melander M, Hedenbro J, Almgren P, and Groop LC

The Journal of clinical endocrinology and metabolism 85(8):2801-4, 2000 Aug - Who cited this? | PubMed ID: 10946885 | Fulltext

Insulin secretion and insulin sensitivity in relation to glucose tolerance: lessons from the Botnia Study.

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Tripathy D, Carlsson M, Almgren P, Isomaa B, Taskinen MR, Tuomi T, and Groop LC

Diabetes 49(6):975-80, 2000 Jun - Who cited this? | PubMed ID: 10866050 | Fulltext

Hepatocyte nuclear factor-1 beta (MODY5) gene mutations in Scandinavian families with early-onset diabetes or kidney disease or both.

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Weng JP, Lehto M, Forsblom C, Huang X, Li H, and Groop LC

Diabetologia 43(1):131-2, 2000 Jan - Who cited this? | PubMed ID: 10672455 | Fulltext

Angiotensin converting enzyme (ACE) gene polymorphism in sarcoidosis in relation to associated autoimmune diseases.

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Papadopoulos KI, Melander O, Orho-Melander M, Groop LC, Carlsson M, and Hallengren B

Journal of internal medicine 247(1):71-7, 2000 Jan - Who cited this? | PubMed ID: 10672133 | Fulltext

Heritability of albumin excretion rate in families of patients with Type II diabetes.

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Forsblom CM, Kanninen T, Lehtovirta M, Saloranta C, and Groop LC

Diabetologia 42(11):1359-66, 1999 Nov - Who cited this? | PubMed ID: 10550421 | Fulltext

Effect of 6 months of GH treatment on myosin heavy chain composition in GH-deficient patients.

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Daugaard JR, Bramnert M, Manhem P, Endre T, Groop LC, Löfman M, and Richter EA

European journal of endocrinology / European Federation of Endocrine Societies 141(4):342-9, 1999 Oct - Who cited this? | PubMed ID: 10526246 | Fulltext

A paired-sibling analysis of the XbaI polymorphism in the muscle glycogen synthase gene.

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Orho-Melander M, Almgren P, Kanninen T, Forsblom C, and Groop LC

Diabetologia 42(9):1138-45, 1999 Sep - Who cited this? | PubMed ID: 10447527 | Fulltext

Growth hormone response to the insulin tolerance and clonidine tests in type 1 diabetes.

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Almqvist EG, Groop LC, and Manhem PJ

Scandinavian journal of clinical and laboratory investigation 59(5):375-82, 1999 Aug - Who cited this? | PubMed ID: 10533850 | Fulltext

Insulin resistance: the fundamental trigger of type 2 diabetes.

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Groop LC

Diabetes, obesity & metabolism 1 Suppl 1:S1-7, 1999 May - Who cited this? | PubMed ID: 11220283 | Fulltext

Expression of naturally occurring variants in the muscle glycogen synthase gene.

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Orho-Melander M, Shimomura H, Sanke T, Rasmussen SK, Nanjo K, Pedersen O, and Groop LC

Diabetes 48(4):918-20, 1999 Apr - Who cited this? | PubMed ID: 10102713 | Fulltext

Pathogenesis of insulin resistance in type 2 diabetes: a collision between thrifty genes and an affluent environment.

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Groop LC

Drugs 58 Suppl 1:11-2; discussion 75-82, 1999 - Who cited this? | PubMed ID: 10576518 | Fulltext

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