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Papers authored by Grandis JR

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Role of polymorphic Fc gamma receptor IIIa and EGFR expression level in cetuximab mediated, NK cell dependent in vitro cytotoxicity of head and neck squamous cell carcinoma cells.

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López-Albaitero A, Lee SC, Morgan S, Grandis JR, Gooding WE, Ferrone S, and Ferris RL

Cancer immunology, immunotherapy : CII 58(11):1855-64, 2009 Nov - Who cited this? | PubMed ID: 19319529 | Fulltext

Cross-talk between estrogen receptor and epidermal growth factor receptor in head and neck squamous cell carcinoma.

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Egloff AM, Rothstein ME, Seethala R, Siegfried JM, Grandis JR, and Stabile LP

Clinical cancer research : an official journal of the American Association for Cancer Research 15(21):6529-40, 2009 Nov 1 - Who cited this? | PubMed ID: 19825947 | Fulltext

STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitro.

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Lui VW, Wong EY, Ho Y, Hong B, Wong SC, Tao Q, Choi GC, Au TC, Ho K, Yau DM, Ma BB, Hui EP, Chan AS, Tsang CM, Tsao SW, Grandis JR,

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International journal of cancer. Journal international du cancer 125(8):1884-93, 2009 Oct 15 - Who cited this? | PubMed ID: 19588483 | Fulltext

Bortezomib up-regulates activated signal transducer and activator of transcription-3 and synergizes with inhibitors of signal transducer and activator of transcription-3 to promote head and neck squamous cell carcinoma cell death.

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Li C, Zang Y, Sen M, Leeman-Neill RJ, Man DS, Grandis JR, and Johnson DE

Molecular cancer therapeutics 8(8):2211-20, 2009 Aug - Who cited this? | PubMed ID: 19638453 | Fulltext

PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells.

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Sun Q, Ming L, Thomas SM, Wang Y, Chen ZG, Ferris RL, Grandis JR, Zhang L, and Yu J

Oncogene 28(24):2348-57, 2009 Jun 18 - Who cited this? | PubMed ID: 19421143 | Fulltext

HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer.

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Knowles LM, Stabile LP, Egloff AM, Rothstein ME, Thomas SM, Gubish CT, Lerner EC, Seethala RR, Suzuki S, Quesnelle KM, Morgan S, Ferris RL, Grandis JR, and Siegfried JM

Clinical cancer research : an official journal of the American Association for Cancer Research 15(11):3740-50, 2009 Jun 1 - Who cited this? | PubMed ID: 19470725 | Fulltext

ABT-737 synergizes with chemotherapy to kill head and neck squamous cell carcinoma cells via a Noxa-mediated pathway.

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Li R, Zang Y, Li C, Patel NS, Grandis JR, and Johnson DE

Molecular pharmacology 75(5):1231-9, 2009 May - Who cited this? | PubMed ID: 19246337 | Fulltext

Targeting angiogenesis from premalignancy to metastases.

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Grandis JR and Argiris A

Cancer prevention research (Philadelphia, Pa.) 2(4):291-4, 2009 Apr - Who cited this? | PubMed ID: 19336719 | Fulltext

Intratumoral epidermal growth factor receptor antisense DNA therapy in head and neck cancer: first human application and potential antitumor mechanisms.

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Lai SY, Koppikar P, Thomas SM, Childs EE, Egloff AM, Seethala RR, Branstetter BF, Gooding WE, Muthukrishnan A, Mountz JM, Lui VW, Shin DM, Agarwala SS, Johnson R, Couture LA, Myers EN,

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Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27(8):1235-42, 2009 Mar 10 - Who cited this? | PubMed ID: 19204206 | Fulltext

Molecular target approaches in head and neck cancer: epidermal growth factor receptor and beyond.

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Harari PM, Wheeler DL, and Grandis JR

Seminars in radiation oncology 19(1):63-8, 2009 Jan - Who cited this? | PubMed ID: 19028347 | Fulltext

Improving Response Rates to EGFR-Targeted Therapies for Head and Neck Squamous Cell Carcinoma: Candidate Predictive Biomarkers and Combination Treatment with Src Inhibitors.

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Egloff AM and Grandis JR

Journal of oncology 2009:896407, 2009 - Who cited this? | PubMed ID: 19636423 | Fulltext

Constitutive activation of signal transducer and activator of transcription 5 contributes to tumor growth, epithelial-mesenchymal transition, and resistance to epidermal growth factor receptor targeting.

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Koppikar P, Lui VW, Man D, Xi S, Chai RL, Nelson E, Tobey AB, and Grandis JR

Clinical cancer research : an official journal of the American Association for Cancer Research 14(23):7682-90, 2008 Dec 1 - Who cited this? | PubMed ID: 19047094 | Fulltext

Kinin b2 receptor mediates induction of cyclooxygenase-2 and is overexpressed in head and neck squamous cell carcinomas.

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Zhang W, Bhola N, Kalyankrishna S, Gooding W, Hunt J, Seethala R, Grandis JR, and Siegfried JM

Molecular cancer research : MCR 6(12):1946-56, 2008 Dec - Who cited this? | PubMed ID: 19074839 | Fulltext

Genetic screening for oral human papillomavirus infections and cancers of the head and neck.

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Sok JC and Grandis JR

Clinical cancer research : an official journal of the American Association for Cancer Research 14(21):6723-4, 2008 Nov 1 - Who cited this? | PubMed ID: 18980962 | Fulltext

Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells.

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Zou H, Thomas SM, Yan ZW, Grandis JR, Vogt A, and Li LY

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2008 Oct 2 - Who cited this? | PubMed ID: 18832597 | Fulltext

Lack of toxicity of a STAT3 decoy oligonucleotide.

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Sen M, Tosca PJ, Zwayer C, Ryan MJ, Johnson JD, Knostman KA, Giclas PC, Peggins JO, Tomaszewski JE, McMurray TP, Li C, Leibowitz MS, Ferris RL, Gooding WE, Thomas SM, Johnson DE,

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Cancer chemotherapy and pharmacology, 2008 Sep 3 - Who cited this? | PubMed ID: 18766340 | Fulltext

ErbB receptors in the biology and pathology of the aerodigestive tract.

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Morgan S and Grandis JR

Experimental cell research, 2008 Aug 23 - Who cited this? | PubMed ID: 18778701 | Fulltext

Resveratrol causes COX-2- and p53-dependent apoptosis in head and neck squamous cell cancer cells.

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Lin HY, Sun M, Tang HY, Simone TM, Wu YH, Grandis JR, Cao HJ, Davis PJ, and Davis FB

Journal of cellular biochemistry 104(6):2131, 2008 Aug 15 - Who cited this? | PubMed ID: 18446786 | Fulltext

Gefitinib potentiates myeloid cell differentiation by ATRA.

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Miranda MB, Duan R, Thomas SM, Grandis JR, Redner RL, Jones JE, and Johnson DE

Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 22(8):1624-7, 2008 Aug - Who cited this? | PubMed ID: 18305561 | Fulltext

Combined inhibition of c-Src and epidermal growth factor receptor abrogates growth and invasion of head and neck squamous cell carcinoma.

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Koppikar P, Choi SH, Egloff AM, Cai Q, Suzuki S, Freilino M, Nozawa H, Thomas SM, Gooding WE, Siegfried JM, and Grandis JR

Clinical cancer research : an official journal of the American Association for Cancer Research 14(13):4284-91, 2008 Jul 1 - Who cited this? | PubMed ID: 18594011 | Fulltext

Combined Inhibition of PLC{gamma}-1 and c-Src abrogates epidermal growth factor receptor-mediated head and neck squamous cell carcinoma invasion.

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Nozawa H, Howell G, Suzuki S, Zhang Q, Qi Y, Klein-Seetharaman J, Wells A, Grandis JR, and Thomas SM

Clinical cancer research : an official journal of the American Association for Cancer Research 14(13):4336-44, 2008 Jul 1 - Who cited this? | PubMed ID: 18594017 | Fulltext

Bortezomib induces apoptosis via Bim and Bik up-regulation and synergizes with cisplatin in the killing of head and neck squamous cell carcinoma cells.

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Li C, Li R, Grandis JR, and Johnson DE

Molecular cancer therapeutics 7(6):1647, 2008 Jun - Who cited this? | PubMed ID: 18566236 | Fulltext

Targeting epidermal growth factor receptor and SRC pathways in head and neck cancer.

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Egloff AM and Grandis JR

Seminars in oncology 35(3):286, 2008 Jun - Who cited this? | PubMed ID: 18544443 | Fulltext

Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck.

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Boehm AL, Sen M, Seethala R, Gooding WE, Freilino M, Wong SM, Wang S, Johnson DE, and Grandis JR

Molecular pharmacology 73(6):1632, 2008 Jun - Who cited this? | PubMed ID: 18326051 | Fulltext

Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growth.

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Yan Z, Zou H, Tian F, Grandis JR, Mixson AJ, Lu PY, and Li LY

Molecular cancer therapeutics 7(6):1355, 2008 Jun - Who cited this? | PubMed ID: 18524845 | Fulltext

Introduction: head and neck cancer.

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Vokes EE, Cohen EE, and Grandis JR

Seminars in oncology 35(3):196-7, 2008 Jun - Who cited this? | PubMed ID: 18544434 | Fulltext

Emerging perspectives in epidermal growth factor receptor targeting in head and neck cancer.

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Kim S, Grandis JR, Rinaldo A, Takes RP, and Ferlito A

Head & neck 30(5):667-74, 2008 May - Who cited this? | PubMed ID: 18383530 | Fulltext

Antitumor mechanisms of systemically administered epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck.

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Thomas SM, Ogagan MJ, Freilino ML, Strychor S, Walsh DR, Gooding WE, Grandis JR, and Zamboni WC

Molecular pharmacology 73(3):627-38, 2008 Mar - Who cited this? | PubMed ID: 18025070 | Fulltext

Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes.

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Seethala RR, Gooding WE, Handler PN, Collins B, Zhang Q, Siegfried JM, and Grandis JR

Clinical cancer research : an official journal of the American Association for Cancer Research 14(5):1303-9, 2008 Mar 1 - Who cited this? | PubMed ID: 18316548 | Fulltext

Long-term results of a phase III randomized trial of postoperative radiotherapy with or without carboplatin in patients with high-risk head and neck cancer.

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Argiris A, Karamouzis MV, Johnson JT, Heron DE, Myers E, Eibling D, Cano E, Urba S, Gluckman J, Grandis JR, Wang Y, and Agarwala SS

The Laryngoscope 118(3):444-9, 2008 Mar - Who cited this? | PubMed ID: 18091334 | Fulltext

Crosstalk between G-protein-coupled receptors and epidermal growth factor receptor in cancer.

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Bhola NE and Grandis JR

Frontiers in bioscience : a journal and virtual library 13:1857-65, 2008 - Who cited this? | PubMed ID: 17981673 | Fulltext

Clinical applications of gene therapy in head and neck cancer.

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Karamouzis MV, Argiris A, and Grandis JR

Current gene therapy 7(6):446-57, 2007 Dec - Who cited this? | PubMed ID: 18045104 | Fulltext

Targeting antiapoptotic Bcl-2 family members with cell-permeable BH3 peptides induces apoptosis signaling and death in head and neck squamous cell carcinoma cells.

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Li R, Boehm AL, Miranda MB, Shangary S, Grandis JR, and Johnson DE

Neoplasia (New York, N.Y.) 9(10):801, 2007 Oct - Who cited this? | PubMed ID: 17971900 | Fulltext

STAT-mediated EGFR signaling in cancer.

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Quesnelle KM, Boehm AL, and Grandis JR

Journal of cellular biochemistry 102(2):311-9, 2007 Oct 1 - Who cited this? | PubMed ID: 17661350 | Fulltext

NF-kappaB gene signatures and p53 mutations in head and neck squamous cell carcinoma.

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Ferris RL and Grandis JR

Clinical cancer research : an official journal of the American Association for Cancer Research 13(19):5663-4, 2007 Oct 1 - Who cited this? | PubMed ID: 17908953 | Fulltext

Advances and challenges in aerodigestive epithelial cancer: meeting summary and research opportunities.

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Grandis JR, Carbone DP, and Rustgi AK

Cancer research 67(16):7556-8, 2007 Aug 15 - Who cited this? | PubMed ID: 17686829 | Fulltext

Therapies directed against epidermal growth factor receptor in aerodigestive carcinomas.

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Karamouzis MV, Grandis JR, and Argiris A

JAMA : the journal of the American Medical Association 298(1):70, 2007 Jul 4 - Who cited this? | PubMed ID: 17609492 | Fulltext

Multiple cytokine and growth factor serum biomarkers predict therapeutic response and survival in advanced-stage head and neck cancer patients.

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Bigbee WL, Grandis JR, and Siegfried JM

Clinical cancer research : an official journal of the American Association for Cancer Research 13(11):3107-8, 2007 Jun 1 - Who cited this? | PubMed ID: 17545511 | Fulltext

Aberrant kinase signaling: lessons from head and neck cancer.

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Nelson EG and Grandis JR

Future oncology (London, England) 3(3):353-61, 2007 Jun - Who cited this? | PubMed ID: 17547530 | Fulltext

Altered inflammatory gene expression underlies increased susceptibility to murine postoperative ileus with advancing age.

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Moore BA, Albers KM, Davis BM, Grandis JR, Tögel S, and Bauer AJ

American journal of physiology. Gastrointestinal and liver physiology 292(6):G1650-9, 2007 Jun - Who cited this? | PubMed ID: 17363464 | Fulltext

Antiproliferative mechanisms of a transcription factor decoy targeting signal transducer and activator of transcription (STAT) 3: the role of STAT1.

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Lui VW, Boehm AL, Koppikar P, Leeman RJ, Johnson D, Ogagan M, Childs E, Freilino M, and Grandis JR

Molecular pharmacology 71(5):1435-43, 2007 May - Who cited this? | PubMed ID: 17325127 | Fulltext

Association of the EGFR intron 1 CA repeat length with lung cancer risk.

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Zhang W, Weissfeld JL, Romkes M, Land SR, Grandis JR, and Siegfried JM

Molecular carcinogenesis 46(5):372-80, 2007 May - Who cited this? | PubMed ID: 17219440 | Fulltext

Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib.

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Liu X, Carlisle DL, Swick MC, Gaither-Davis A, Grandis JR, and Siegfried JM

Experimental cell research 313(7):1361-72, 2007 Apr 15 - Who cited this? | PubMed ID: 17349623 | Fulltext

Antitumor mechanisms of combined gastrin-releasing peptide receptor and epidermal growth factor receptor targeting in head and neck cancer.

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Zhang Q, Bhola NE, Lui VW, Siwak DR, Thomas SM, Gubish CT, Siegfried JM, Mills GB, Shin D, and Grandis JR

Molecular cancer therapeutics 6(4):1414-24, 2007 Apr - Who cited this? | PubMed ID: 17431120 | Fulltext

Selective inhibition of ADAM metalloproteases as a novel approach for modulating ErbB pathways in cancer.

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Fridman JS, Caulder E, Hansbury M, Liu X, Yang G, Wang Q, Lo Y, Zhou BB, Pan M, Thomas SM, Grandis JR, Zhuo J, Yao W, Newton RC, Friedman SM, Scherle PA,

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Clinical cancer research : an official journal of the American Association for Cancer Research 13(6):1892-902, 2007 Mar 15 - Who cited this? | PubMed ID: 17363546 | Fulltext

Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.

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Lin CJ, Grandis JR, Carey TE, Gollin SM, Whiteside TL, Koch WM, Ferris RL, and Lai SY

Head & neck 29(2):163-88, 2007 Feb - Who cited this? | PubMed ID: 17312569 | Fulltext

The role of CD44 in HNSCC.

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Nelson AD and Grandis JR

Cancer biology & therapy 6(1):125-6, 2007 Jan - Who cited this? | PubMed ID: 17297303 | Fulltext

Established and emerging concepts in epidermal growth factor receptor biology.

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Grandis JR

International journal of radiation oncology, biology, physics 69(2 Suppl):S22-4, 2007 - Who cited this? | PubMed ID: 17848285 | Fulltext

Cross-talk between G protein-coupled receptor and epidermal growth factor receptor signaling pathways contributes to growth and invasion of head and neck squamous cell carcinoma.

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Thomas SM, Bhola NE, Zhang Q, Contrucci SC, Wentzel AL, Freilino ML, Gooding WE, Siegfried JM, Chan DC, and Grandis JR

Cancer research 66(24):11831-9, 2006 Dec 15 - Who cited this? | PubMed ID: 17178880 | Fulltext

Understanding the presence and function of erythropoietin receptors on cancer cells.

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Lai SY and Grandis JR

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 24(29):4675, 2006 Oct 10 - Who cited this? | PubMed ID: 17028292 | Fulltext

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