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Papers authored by Goodyear LJ

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Effects of exercise training on subcutaneous and visceral adipose tissue in normal- and high-fat diet-fed rats.

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Gollisch KS, Brandauer J, Jessen N, Toyoda T, Nayer A, Hirshman MF, and Goodyear LJ

American journal of physiology. Endocrinology and metabolism 297(2):E495-504, 2009 Aug - Who cited this? | PubMed ID: 19491293 | Fulltext

Stretch-stimulated glucose uptake in skeletal muscle is mediated by reactive oxygen species and p38 MAP-kinase.

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Chambers MA, Moylan JS, Smith JD, Goodyear LJ, and Reid MB

The Journal of physiology 587(Pt 13):3363-73, 2009 Jul 1 - Who cited this? | PubMed ID: 19403598 | Fulltext

Estradiol stimulates Akt, AMP-activated protein kinase (AMPK) and TBC1D1/4, but not glucose uptake in rat soleus.

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Rogers NH, Witczak CA, Hirshman MF, Goodyear LJ, and Greenberg AS

Biochemical and biophysical research communications 382(4):646-50, 2009 May 15 - Who cited this? | PubMed ID: 19265681 | Fulltext

Response: skeletal muscle precursor grafts in dystrophic mice.

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Cerletti M, Stevenson K, Neuberg D, Jurga S, Witczak CA, Hirshman MF, Shadrach JL, Goodyear LJ, and Wagers AJ

Cell 135(6):998-9, 2008 Dec 12 - Who cited this? | PubMed ID: 19070566 | Fulltext

Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice.

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Fujii N, Ho RC, Manabe Y, Jessen N, Toyoda T, Holland WL, Summers SA, Hirshman MF, and Goodyear LJ

Diabetes 57(11):2958-66, 2008 Nov - Who cited this? | PubMed ID: 18728234 | Fulltext

The exercise pill--too good to be true?.

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Goodyear LJ

The New England journal of medicine 359(17):1842-4, 2008 Oct 23 - Who cited this? | PubMed ID: 18946072 | Fulltext

AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism.

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Witczak CA, Sharoff CG, and Goodyear LJ

Cellular and molecular life sciences : CMLS, 2008 Sep 22 - Who cited this? | PubMed ID: 18810325 | Fulltext

Endogenous Peroxisome Proliferator-Activated Receptor {gamma} Augments Fatty Acid Uptake in Oxidative Muscle.

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Norris AW, Hirshman MF, Yao J, Jessen N, Musi N, Chen L, Sivitz WI, Goodyear LJ, and Kahn CR

Endocrinology, 2008 Jul 24 - Who cited this? | PubMed ID: 18653710 | Fulltext

Highly Efficient, Functional Engraftment of Skeletal Muscle Stem Cells in Dystrophic Muscles.

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Cerletti M, Jurga S, Witczak CA, Hirshman MF, Shadrach JL, Goodyear LJ, and Wagers AJ

Cell 134(1):37, 2008 Jul 11 - Who cited this? | PubMed ID: 18614009 | Fulltext

LKB1 and AMPK and the regulation of skeletal muscle metabolism.

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Koh HJ, Brandauer J, and Goodyear LJ

Current opinion in clinical nutrition and metabolic care 11(3):227, 2008 May - Who cited this? | PubMed ID: 18403917 | Fulltext

Oxidative stress stimulates skeletal muscle glucose uptake through a phosphatidylinositol 3-kinase-dependent pathway.

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Higaki Y, Mikami T, Fujii N, Hirshman MF, Koyama K, Seino T, Tanaka K, and Goodyear LJ

American journal of physiology. Endocrinology and metabolism 294(5):E889-97, 2008 May - Who cited this? | PubMed ID: 18303121 | Fulltext

Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle.

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Taylor EB, An D, Kramer HF, Yu H, Fujii NL, Roeckl KS, Bowles N, Hirshman MF, Xie J, Feener EP, and Goodyear LJ

The Journal of biological chemistry 283(15):9787, 2008 Apr 11 - Who cited this? | PubMed ID: 18276596 | Fulltext

Signaling mechanisms in skeletal muscle: Acute responses and chronic adaptations to exercise.

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Röckl KS, Witczak CA, and Goodyear LJ

IUBMB life 60(3):145-53, 2008 Mar - Who cited this? | PubMed ID: 18380005 | Fulltext

Large GLUT4 vesicles are stationary while locally and reversibly depleted during transient insulin stimulation of skeletal muscle of living mice: imaging analysis of GLUT4-enhanced green fluorescent protein vesicle dynamics.

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Lauritzen HP, Galbo H, Brandauer J, Goodyear LJ, and Ploug T

Diabetes 57(2):315-24, 2008 Feb - Who cited this? | PubMed ID: 17977960 | Fulltext

Insulin promotes glycogen synthesis in the absence of GSK3 phosphorylation in skeletal muscle.

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Bouskila M, Hirshman MF, Jensen J, Goodyear LJ, and Sakamoto K

American journal of physiology. Endocrinology and metabolism 294(1):E28-35, 2008 Jan - Who cited this? | PubMed ID: 18003720 | Fulltext

Targeting skeletal muscle AMP-activated protein kinase to treat type 2 diabetes.

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Taylor EB and Goodyear LJ

Current diabetes reports 7(6):399, 2007 Dec - Who cited this? | PubMed ID: 18254999 | Fulltext

Calmodulin-binding domain of AS160 regulates contraction- but not insulin-stimulated glucose uptake in skeletal muscle.

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Kramer HF, Taylor EB, Witczak CA, Fujii N, Hirshman MF, and Goodyear LJ

Diabetes 56(12):2854-62, 2007 Dec - Who cited this? | PubMed ID: 17717281 | Fulltext

Dissociation of AMP-activated protein kinase and p38 mitogen-activated protein kinase signaling in skeletal muscle.

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Ho RC, Fujii N, Witters LA, Hirshman MF, and Goodyear LJ

Biochemical and biophysical research communications 362(2):354-9, 2007 Oct 19 - Who cited this? | PubMed ID: 17709097 | Fulltext

Role of AMP-activated protein kinase in exercise capacity, whole body glucose homeostasis, and glucose transport in skeletal muscle -insight from analysis of a transgenic mouse model-.

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Fujii N, Seifert MM, Kane EM, Peter LE, Ho RC, Winstead S, Hirshman MF, and Goodyear LJ

Diabetes research and clinical practice 77 Suppl 1:S92-8, 2007 Sep - Who cited this? | PubMed ID: 17452058 | Fulltext

Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift.

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Röckl KS, Hirshman MF, Brandauer J, Fujii N, Witters LA, and Goodyear LJ

Diabetes 56(8):2062-9, 2007 Aug - Who cited this? | PubMed ID: 17513699 | Fulltext

Exercise, MAPK, and NF-kappaB signaling in skeletal muscle.

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Kramer HF and Goodyear LJ

Journal of applied physiology (Bethesda, Md. : 1985) 103(1):388-95, 2007 Jul - Who cited this? | PubMed ID: 17303713 | Fulltext

Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes.

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Koh HJ, Hirshman MF, He H, Li Y, Manabe Y, Balschi JA, and Goodyear LJ

The Biochemical journal 403(3):473-81, 2007 May 1 - Who cited this? | PubMed ID: 17253964 | Fulltext

Ca2+/calmodulin-dependent protein kinase kinase-alpha regulates skeletal muscle glucose uptake independent of AMP-activated protein kinase and Akt activation.

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Witczak CA, Fujii N, Hirshman MF, and Goodyear LJ

Diabetes 56(5):1403-9, 2007 May - Who cited this? | PubMed ID: 17287469 | Fulltext

Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage.

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Luptak I, Shen M, He H, Hirshman MF, Musi N, Goodyear LJ, Yan J, Wakimoto H, Morita H, Arad M, Seidman CE, Seidman JG, Ingwall JS, Balschi JA, and Tian R

The Journal of clinical investigation 117(5):1432-9, 2007 May - Who cited this? | PubMed ID: 17431505 | Fulltext

Genetic model for the chronic activation of skeletal muscle AMP-activated protein kinase leads to glycogen accumulation.

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Barré L, Richardson C, Hirshman MF, Brozinick J, Fiering S, Kemp BE, Goodyear LJ, and Witters LA

American journal of physiology. Endocrinology and metabolism 292(3):E802-11, 2007 Mar - Who cited this? | PubMed ID: 17106064 | Fulltext

JNK1 deficiency does not enhance muscle glucose metabolism in lean mice.

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Witczak CA, Hirshman MF, Jessen N, Fujii N, Seifert MM, Brandauer J, Hotamisligil GS, and Goodyear LJ

Biochemical and biophysical research communications 350(4):1063-8, 2006 Dec 1 - Who cited this? | PubMed ID: 17045576 | Fulltext

Role of Akt2 in contraction-stimulated cell signaling and glucose uptake in skeletal muscle.

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Sakamoto K, Arnolds DE, Fujii N, Kramer HF, Hirshman MF, and Goodyear LJ

American journal of physiology. Endocrinology and metabolism 291(5):E1031-7, 2006 Nov - Who cited this? | PubMed ID: 16803855 | Fulltext

AMP-activated protein kinase and the regulation of glucose transport.

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Fujii N, Jessen N, and Goodyear LJ

American journal of physiology. Endocrinology and metabolism 291(5):E867-77, 2006 Nov - Who cited this? | PubMed ID: 16822958 | Fulltext

Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3.

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Koh HJ, Arnolds DE, Fujii N, Tran TT, Rogers MJ, Jessen N, Li Y, Liew CW, Ho RC, Hirshman MF, Kulkarni RN, Kahn CR, and Goodyear LJ

Molecular and cellular biology 26(22):8217-27, 2006 Nov - Who cited this? | PubMed ID: 16966378 | Fulltext

AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle.

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Kramer HF, Witczak CA, Taylor EB, Fujii N, Hirshman MF, and Goodyear LJ

The Journal of biological chemistry 281(42):31478-85, 2006 Oct 20 - Who cited this? | PubMed ID: 16935857 | Fulltext

Muscle-specific overexpression of wild type and R225Q mutant AMP-activated protein kinase gamma3-subunit differentially regulates glycogen accumulation.

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Yu H, Hirshman MF, Fujii N, Pomerleau JM, Peter LE, and Goodyear LJ

American journal of physiology. Endocrinology and metabolism 291(3), 2006 Sep - Who cited this? | PubMed ID: 16638825 | Fulltext

Insulin-stimulated insulin receptor substrate-2-associated phosphatidylinositol 3-kinase activity is enhanced in human skeletal muscle after exercise.

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Howlett KF, Sakamoto K, Yu H, Goodyear LJ, and Hargreaves M

Metabolism: clinical and experimental 55(8):1046-52, 2006 Aug - Who cited this? | PubMed ID: 16839840 | Fulltext

Regulation of dishevelled and beta-catenin in rat skeletal muscle: an alternative exercise-induced GSK-3beta signaling pathway.

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Aschenbach WG, Ho RC, Sakamoto K, Fujii N, Li Y, Kim YB, Hirshman MF, and Goodyear LJ

American journal of physiology. Endocrinology and metabolism 291(1), 2006 Jul - Who cited this? | PubMed ID: 16478782 | Fulltext

Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle.

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Kramer HF, Witczak CA, Fujii N, Jessen N, Taylor EB, Arnolds DE, Sakamoto K, Hirshman MF, and Goodyear LJ

Diabetes 55(7):2067, 2006 Jul - Who cited this? | PubMed ID: 16804077 | Fulltext

Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle.

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Kuhl JE, Ruderman NB, Musi N, Goodyear LJ, Patti ME, Crunkhorn S, Dronamraju D, Thorell A, Nygren J, Ljungkvist O, Degerblad M, Stahle A, Brismar TB, Andersen KL, Saha AK, Efendic S,

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American journal of physiology. Endocrinology and metabolism 290(6), 2006 Jun - Who cited this? | PubMed ID: 16434556 | Fulltext

Loss of class IA PI3K signaling in muscle leads to impaired muscle growth, insulin response, and hyperlipidemia.

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Luo J, Sobkiw CL, Hirshman MF, Logsdon MN, Li TQ, Goodyear LJ, and Cantley LC

Cell metabolism 3(5):355, 2006 May - Who cited this? | PubMed ID: 16679293 | Fulltext

Insulin resistance and improvements in signal transduction.

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Musi N and Goodyear LJ

Endocrine 29(1):73-80, 2006 Feb - Who cited this? | PubMed ID: 16622294 | Fulltext

AMP-activated protein kinase alpha2 activity is not essential for contraction- and hyperosmolarity-induced glucose transport in skeletal muscle.

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Fujii N, Hirshman MF, Kane EM, Ho RC, Peter LE, Seifert MM, and Goodyear LJ

The Journal of biological chemistry 280(47):39033-41, 2005 Nov 25 - Who cited this? | PubMed ID: 16186119 | Fulltext

Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy.

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Ahmad F, Arad M, Musi N, He H, Wolf C, Branco D, Perez-Atayde AR, Stapleton D, Bali D, Xing Y, Tian R, Goodyear LJ, Berul CI, Ingwall JS, Seidman CE, and Seidman JG

Circulation 112(20):3140-8, 2005 Nov 15 - Who cited this? | PubMed ID: 16275868 | Fulltext

Muscle-specific deletion of the Glut4 glucose transporter alters multiple regulatory steps in glycogen metabolism.

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Kim YB, Peroni OD, Aschenbach WG, Minokoshi Y, Kotani K, Zisman A, Kahn CR, Goodyear LJ, and Kahn BB

Molecular and cellular biology 25(21):9713-23, 2005 Nov - Who cited this? | PubMed ID: 16227617 | Fulltext

Regulation of IkappaB kinase and NF-kappaB in contracting adult rat skeletal muscle.

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Ho RC, Hirshman MF, Li Y, Cai D, Farmer JR, Aschenbach WG, Witczak CA, Shoelson SE, and Goodyear LJ

American journal of physiology. Cell physiology 289(4), 2005 Oct - Who cited this? | PubMed ID: 15888549 | Fulltext

Contraction signaling to glucose transport in skeletal muscle.

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Jessen N and Goodyear LJ

Journal of applied physiology (Bethesda, Md. : 1985) 99(1):330-7, 2005 Jul - Who cited this? | PubMed ID: 16036906 | Fulltext

Functional role of AMP-activated protein kinase in the heart during exercise.

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Musi N, Hirshman MF, Arad M, Xing Y, Fujii N, Pomerleau J, Ahmad F, Berul CI, Seidman JG, Tian R, and Goodyear LJ

FEBS letters 579(10):2045-50, 2005 Apr 11 - Who cited this? | PubMed ID: 15811316 | Fulltext

Long-term AICAR administration and exercise prevents diabetes in ZDF rats.

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Pold R, Jensen LS, Jessen N, Buhl ES, Schmitz O, Flyvbjerg A, Fujii N, Goodyear LJ, Gotfredsen CF, Brand CL, and Lund S

Diabetes 54(4):928-34, 2005 Apr - Who cited this? | PubMed ID: 15793229 | Fulltext

Beta-cell secretory dysfunction in the pathogenesis of low birth weight-associated diabetes: a murine model.

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Jimenez-Chillaron JC, Hernandez-Valencia M, Reamer C, Fisher S, Joszi A, Hirshman M, Oge A, Walrond S, Przybyla R, Boozer C, Goodyear LJ, and Patti ME

Diabetes 54(3):702-11, 2005 Mar - Who cited this? | PubMed ID: 15734846 | Fulltext

Overexpression or ablation of JNK in skeletal muscle has no effect on glycogen synthase activity.

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Fujii N, Boppart MD, Dufresne SD, Crowley PF, Jozsi AC, Sakamoto K, Yu H, Aschenbach WG, Kim S, Miyazaki H, Rui L, White MF, Hirshman MF, and Goodyear LJ

American journal of physiology. Cell physiology 287(1), 2004 Jul - Who cited this? | PubMed ID: 15013949 | Fulltext

Exercise regulates Akt and glycogen synthase kinase-3 activities in human skeletal muscle.

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Sakamoto K, Arnolds DE, Ekberg I, Thorell A, and Goodyear LJ

Biochemical and biophysical research communications 319(2):419-25, 2004 Jun 25 - Who cited this? | PubMed ID: 15178423 | Fulltext

Regulation of glucose transport by the AMP-activated protein kinase.

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Fujii N, Aschenbach WG, Musi N, Hirshman MF, and Goodyear LJ

The Proceedings of the Nutrition Society 63(2):205-10, 2004 May - Who cited this? | PubMed ID: 15294031 | Fulltext

cDNA cloning and functional characterization of a novel splice variant of c-Cbl-associated protein from mouse skeletal muscle.

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Alcazar O, Ho RC, Fujii N, and Goodyear LJ

Biochemical and biophysical research communications 317(1):285-93, 2004 Apr 23 - Who cited this? | PubMed ID: 15047181 | Fulltext

Cloning and characterization of mouse 5'-AMP-activated protein kinase gamma3 subunit.

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Yu H, Fujii N, Hirshman MF, Pomerleau JM, and Goodyear LJ

American journal of physiology. Cell physiology 286(2):C283-92, 2004 Feb - Who cited this? | PubMed ID: 14512293 | Fulltext

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Papers authored by Goodyear LJ

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