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Papers authored by Goldstein JL

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Lasker Awards and papal portraiture: turning fields upside down.

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Goldstein JL

Nature medicine 15(10):1137-40, 2009 Oct - Who cited this? | PubMed ID: 19812573 | Fulltext

Accelerated Fatty Acid Oxidation in Muscle Averts Fasting-induced Hepatic Steatosis in SJL/J Mice.

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Guan HP, Goldstein JL, Brown MS, and Liang G

The Journal of biological chemistry 284(36):24644-52, 2009 Sep 4 - Who cited this? | PubMed ID: 19581301 | Fulltext

Screening for pompe disease using a rapid dried blood spot method: Experience of a clinical diagnostic laboratory.

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Goldstein JL, Young SP, Changela M, Dickerson GH, Zhang H, Dai J, Peterson D, Millington DS, Kishnani PS, and Bali DS

Muscle & nerve 40(1):32-6, 2009 Jul - Who cited this? | PubMed ID: 19533645 | Fulltext

Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol.

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Kwon HJ, Abi-Mosleh L, Wang ML, Deisenhofer J, Goldstein JL, Brown MS, and Infante RE

Cell 137(7):1213-24, 2009 Jun 26 - Who cited this? | PubMed ID: 19563754 | Fulltext

The LDL receptor.

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Goldstein JL and Brown MS

Arteriosclerosis, thrombosis, and vascular biology 29(4):431-8, 2009 Apr - Who cited this? | PubMed ID: 19299327 | Fulltext

A cochlearlike model of equal loudness levels for impaired and normal hearing: A new basis for hearing-aid gain-compression prescriptions.

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Goldstein JL

The Journal of the Acoustical Society of America 125(4):2724, 2009 Apr - Who cited this? | PubMed ID: 19355455 | Fulltext

Preference and performance for hearing-aid gain-compression prescriptions, based on a preliminary model of impaired sensitivity to tone intensity.

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Goldstein JL, Valente M, Oz M, and Gilchrist P

The Journal of the Acoustical Society of America 125(4):2724, 2009 Apr - Who cited this? | PubMed ID: 19355456 | Fulltext

Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL.

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Brown MS and Goldstein JL

Journal of lipid research 50 Suppl:S15-27, 2009 Apr - Who cited this? | PubMed ID: 18974038 | Fulltext

Switch-like Control of SREBP-2 Transport Triggered by Small Changes in ER Cholesterol: A Delicate Balance.

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Radhakrishnan A, Goldstein JL, McDonald JG, and Brown MS

Cell metabolism 8(6):512-21, 2008 Dec - Who cited this? | PubMed ID: 19041766 | Fulltext

Exuberant unpredictability: sine qua non for priceless and prizeworthy biomedical research.

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Goldstein JL

Nature medicine 14(10):1029-32, 2008 Oct - Who cited this? | PubMed ID: 18841142 | Fulltext

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes.

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Infante RE, Wang ML, Radhakrishnan A, Kwon HJ, Brown MS, and Goldstein JL

Proceedings of the National Academy of Sciences of the United States of America, 2008 Sep 4 - Who cited this? | PubMed ID: 18772377 | Fulltext

Inhibition of ghrelin O-acyltransferase (GOAT) by octanoylated pentapeptides.

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Yang J, Zhao TJ, Goldstein JL, and Brown MS

Proceedings of the National Academy of Sciences of the United States of America, 2008 Jul 31 - Who cited this? | PubMed ID: 18669668 | Fulltext

From fatty streak to fatty liver: 33 years of joint publications in the JCI.

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Goldstein JL and Brown MS

The Journal of clinical investigation 118(4):1220-2, 2008 Apr - Who cited this? | PubMed ID: 18382725 | Fulltext

Evaluation and treatment of osteochondritis dissecans lesions of the knee.

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Detterline AJ, Goldstein JL, Rue JP, and Bach BR

The journal of knee surgery 21(2):106-15, 2008 Apr - Who cited this? | PubMed ID: 18500061 | Fulltext

Endoscopic Ulcer Rates in Healthy Subjects Associated with Use of Aspirin (81 mg q.d.) Alone or Coadministered with Celecoxib or Naproxen: A randomized, 1-Week Trial.

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Goldstein JL, Aisenberg J, Zakko SF, Berger MF, and Dodge WE

Digestive diseases and sciences 53(3):647-56, 2008 Mar - Who cited this? | PubMed ID: 17676393 | Fulltext

Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone.

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Yang J, Brown MS, Liang G, Grishin NV, and Goldstein JL

Cell 132(3):387, 2008 Feb 8 - Who cited this? | PubMed ID: 18267071 | Fulltext

Selective versus Total Insulin Resistance: A Pathogenic Paradox.

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Brown MS and Goldstein JL

Cell metabolism 7(2):95-6, 2008 Feb - Who cited this? | PubMed ID: 18249166 | Fulltext

Purified NPC1 Protein: II. LOCALIZATION OF STEROL BINDING TO A 240-AMINO ACID SOLUBLE LUMINAL LOOP.

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Infante RE, Radhakrishnan A, Abi-Mosleh L, Kinch LN, Wang ML, Grishin NV, Goldstein JL, and Brown MS

The Journal of biological chemistry 283(2):1064-75, 2008 Jan 11 - Who cited this? | PubMed ID: 17989072 | Fulltext

Purified NPC1 Protein: I. BINDING OF CHOLESTEROL AND OXYSTEROLS TO A 1278-AMINO ACID MEMBRANE PROTEIN.

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Infante RE, Abi-Mosleh L, Radhakrishnan A, Dale JD, Brown MS, and Goldstein JL

The Journal of biological chemistry 283(2):1052-63, 2008 Jan 11 - Who cited this? | PubMed ID: 17989073 | Fulltext

Clinical trial: healing of NSAID-associated gastric ulcers in patients continuing NSAID therapy - a randomized study comparing ranitidine with esomeprazole.

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Goldstein JL, Johanson JF, Hawkey CJ, Suchower LJ, and Brown KA

Alimentary pharmacology & therapeutics 26(8):1101-11, 2007 Oct 15 - Who cited this? | PubMed ID: 17894652 | Fulltext

Celecoxib plus aspirin versus naproxen and lansoprazole plus aspirin: a randomized, double-blind, endoscopic trial.

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Goldstein JL, Cryer B, Amer F, and Hunt B

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 5(10):1167-74, 2007 Oct - Who cited this? | PubMed ID: 17916545 | Fulltext

Creation and revelation: two different routes to advancement in the biomedical sciences.

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Goldstein JL

Nature medicine 13(10):1151-4, 2007 Oct - Who cited this? | PubMed ID: 17917663 | Fulltext

Withdrawal of COX-2 selective inhibitors rofecoxib and valdecoxib: impact on NSAID and gastroprotective drug prescribing and utilization.

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Sun SX, Lee KY, Bertram CT, and Goldstein JL

Current medical research and opinion 23(8):1859-66, 2007 Aug - Who cited this? | PubMed ID: 17605893 | Fulltext

Practical management of Lisfranc injuries in athletes.

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Lattermann C, Goldstein JL, Wukich DK, Lee S, and Bach BR

Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine 17(4):311-5, 2007 Jul - Who cited this? | PubMed ID: 17620787 | Fulltext

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.

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Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL, Erdos MR, Stringham HM, Chines PS, Jackson AU, Prokunina-Olsson L, Ding CJ, Swift AJ, Narisu N, Hu T, Pruim R,

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Science (New York, N.Y.) 316(5829):1341-5, 2007 Jun 1 - Who cited this? | PubMed ID: 17463248 | Fulltext

Small bowel mucosal injury is reduced in healthy subjects treated with celecoxib compared with ibuprofen plus omeprazole, as assessed by video capsule endoscopy.

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Goldstein JL, Eisen GM, Lewis B, Gralnek IM, Aisenberg J, Bhadra P, and Berger MF

Alimentary pharmacology & therapeutics 25(10):1211-22, 2007 May 15 - Who cited this? | PubMed ID: 17451567 | Fulltext

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins.

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Sun LP, Seemann J, Goldstein JL, and Brown MS

Proceedings of the National Academy of Sciences of the United States of America 104(16):6519, 2007 Apr 17 - Who cited this? | PubMed ID: 17428919 | Fulltext

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig.

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Radhakrishnan A, Ikeda Y, Kwon HJ, Brown MS, and Goldstein JL

Proceedings of the National Academy of Sciences of the United States of America 104(16):6511, 2007 Apr 17 - Who cited this? | PubMed ID: 17428920 | Fulltext

Efficacy of esomeprazole for resolution of symptoms of heartburn and acid regurgitation in continuous users of non-steroidal anti-inflammatory drugs.

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Hawkey CJ, Jones RH, Yeomans ND, Scheiman JM, Talley NJ, Goldstein JL, Ahlbom H, and Naesdal J

Alimentary pharmacology & therapeutics 25(7):813-21, 2007 Apr 1 - Who cited this? | PubMed ID: 17373920 | Fulltext

The rate of NSAID-induced endoscopic ulcers increases linearly but not exponentially with age: a pooled analysis of 12 randomised trials.

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Boers M, Tangelder MJ, van Ingen H, Fort JG, and Goldstein JL

Annals of the rheumatic diseases 66(3):417-8, 2007 Mar - Who cited this? | PubMed ID: 16887862 | Fulltext

Lateral meniscus allograft biologic glenoid arthroplasty in total shoulder arthroplasty for young shoulders with degenerative joint disease.

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Nicholson GP, Goldstein JL, Romeo AA, Cole BJ, Hayden JK, Twigg SL, McCarty LP, and Detterline AJ

Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.] 16(5 Suppl):S261-6, 2007 - Who cited this? | PubMed ID: 17507244 | Fulltext

Impact of adherence to concomitant gastroprotective therapy on nonsteroidal-related gastroduodenal ulcer complications.

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Goldstein JL, Howard KB, Walton SM, McLaughlin TP, and Kruzikas DT

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 4(11):1337-45, 2006 Nov - Who cited this? | PubMed ID: 17088110 | Fulltext

Venture science: climbing the ladder to telomerase, cognitive therapy and in situ hybridization.

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Goldstein JL

Nature medicine 12(10):1129, 2006 Oct - Who cited this? | PubMed ID: 17024207 | Fulltext

Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin.

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Engelking LJ, Evers BM, Richardson JA, Goldstein JL, Brown MS, and Liang G

The Journal of clinical investigation 116(9):2356, 2006 Sep - Who cited this? | PubMed ID: 16955138 | Fulltext

Alexia without agraphia in a child with acute disseminated encephalomyelitis.

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Little RD and Goldstein JL

Neurology 67(4):725, 2006 Aug 22 - Who cited this? | PubMed ID: 16924040 | Fulltext

The impact of low-dose aspirin on endoscopic gastric and duodenal ulcer rates in users of a non-selective non-steroidal anti-inflammatory drug or a cyclo-oxygenase-2-selective inhibitor.

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Goldstein JL, Lowry SC, Lanza FL, Schwartz HI, and Dodge WE

Alimentary pharmacology & therapeutics 23(10):1489, 2006 May 15 - Who cited this? | PubMed ID: 16669964 | Fulltext

Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis.

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Gong Y, Lee JN, Brown MS, Goldstein JL, and Ye J

Proceedings of the National Academy of Sciences of the United States of America 103(16):6154, 2006 Apr 18 - Who cited this? | PubMed ID: 16606821 | Fulltext

Intragastric acid control in non-steroidal anti-inflammatory drug users: comparison of esomeprazole, lansoprazole and pantoprazole.

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Goldstein JL, Miner PB, Schlesinger PK, Liu S, and Silberg DG

Alimentary pharmacology & therapeutics 23(8):1189, 2006 Apr 15 - Who cited this? | PubMed ID: 16611280 | Fulltext

Biomedicine. Lowering LDL--not only how low, but how long?.

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Brown MS and Goldstein JL

Science (New York, N.Y.) 311(5768):1721-3, 2006 Mar 24 - Who cited this? | PubMed ID: 16556829 | Fulltext

Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESS-I Study.

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Singh G, Fort JG, Goldstein JL, Levy RA, Hanrahan PS, Bello AE, Andrade-Ortega L, Wallemark C, Agrawal NM, Eisen GM, Stenson WF, Triadafilopoulos G, and SUCCESS-I Investigators

The American journal of medicine 119(3):255-66, 2006 Mar - Who cited this? | PubMed ID: 16490472 | Fulltext

A multicenter, randomized, double-blind, active-comparator, placebo-controlled, parallel-group comparison of the incidence of endoscopic gastric and duodenal ulcer rates with valdecoxib or naproxen in healthy subjects aged 65 to 75 years.

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Goldstein JL, Aisenberg J, Lanza F, Schwartz H, Sands GH, Berger MF, and Pan S

Clinical therapeutics 28(3):340-51, 2006 Mar - Who cited this? | PubMed ID: 16750449 | Fulltext

The CRAL/TRIO and GOLD domain protein CGR-1 promotes induction of vulval cell fates in Caenorhabditis elegans and interacts genetically with the Ras signaling pathway.

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Goldstein JL, Glossip D, Nayak S, and Kornfeld K

Genetics 172(2):929-42, 2006 Feb - Who cited this? | PubMed ID: 16219793 | Fulltext

Protein sensors for membrane sterols.

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Goldstein JL, DeBose-Boyd RA, and Brown MS

Cell 124(1):35, 2006 Jan 13 - Who cited this? | PubMed ID: 16413480 | Fulltext

Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake.

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Gong Y, Lee JN, Lee PC, Goldstein JL, Brown MS, and Ye J

Cell metabolism 3(1):15, 2006 Jan - Who cited this? | PubMed ID: 16399501 | Fulltext

A graphical assessment of p-values from sliding window haplotype tests of association to identify asthma susceptibility loci on chromosome 11q.

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Mathias RA, Gao P, Goldstein JL, Wilson AF, Pugh EW, Furbert-Harris P, Dunston GM, Malveaux FJ, Togias A, Barnes KC, Beaty TH, and Huang SK

BMC genetics 7:38, 2006 - Who cited this? | PubMed ID: 16774684 | Fulltext

Healing of gastric ulcers with esomeprazole versus ranitidine in patients who continued to receive NSAID therapy: a randomized trial.

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Goldstein JL, Johanson JF, Suchower LJ, and Brown KA

The American journal of gastroenterology 100(12):2650-7, 2005 Dec - Who cited this? | PubMed ID: 16393215 | Fulltext

Expression and membrane localization of MCT isoforms along the length of the human intestine.

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Gill RK, Saksena S, Alrefai WA, Sarwar Z, Goldstein JL, Carroll RE, Ramaswamy K, and Dudeja PK

American journal of physiology. Cell physiology 289(4):C846-52, 2005 Oct - Who cited this? | PubMed ID: 15901598 | Fulltext

60 years of winged victories for biomedical research.

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Goldstein JL

Nature medicine 11(10):1023-5, 2005 Oct - Who cited this? | PubMed ID: 16211026 | Fulltext

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.

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Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, and Brown MS

The Journal of clinical investigation 115(9):2489, 2005 Sep - Who cited this? | PubMed ID: 16100574 | Fulltext

Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro.

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Sun LP, Li L, Goldstein JL, and Brown MS

The Journal of biological chemistry 280(28):26483, 2005 Jul 15 - Who cited this? | PubMed ID: 15899885 | Fulltext

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